• Asian Pacific Journal of Cancer Prevention
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• 제15권16호
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• pp.6679-6683
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• 2014

Background: Carcinoid crisis is a life-threating syndrome of neuroendocrine tumors (NETs) characterized by dramatic blood pressure fluctuation, arrhythmias, and bronchospasm. In the era of booming anti-tumor therapeutics, this has become more important since associated stresses can trigger carcinoid crisis. Somatostatin analogues (SSTA) have been recommended for prophylactic administration before intervention procedures for functioning NETs. However, the efficacy is still controversial. The aim of this article is to review efficacy of SSTA for preventing carcinoid crisis. Materials and Methods: PubMed, Cochrane Controlled trials Register, and EMBASE were searched using 'carcinoid crisis' as a search term combining terms with 'somatostatin'; 'octreotide'; 'lanreotide' and 'pasireotide' until December 2013. Results: Twenty-eight articles were retrieved with a total of fifty-three unique patients identified for carcinoid crisis. The most common primary sites of NETs were the small intestine and respiratory tract. The triggering factors for carcinoid crisis included anesthesia/surgery (63.5%), interventional therapy (11.5%), radionuclide therapy (9.6%), examination (7.7%), medication (3.8%), biopsy (2%) and spontaneous (2%). No randomized controlled trials (RCTs) were identified and two case-control studies were included to assess the efficacy of SSTA for preventing carcinoid crisis by meta-analysis. The overall pooled risk of perioperative carcinoid crisis was similar despite the prophylactic administration of SSTA (OR 0.44, 95% CI: 0.14 to 1.35, p=0.15). Conclusions: SSTA wasnot helpful for preventing carcinoid crisis based on a meta-analysis of retrospective studies. Attentive monitoring and careful intervention are essential. Future studies with better quality are needed to clarify any effect of SSTA for preventing carcinoid crisis.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2015년도 학술발표회
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• pp.224-224
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• 2015

The East Asia monsoon is one of the most complex atmospheric phenomena caused by Land-Sea thermal contrast. It plays essential role in fulfilling the water needs of the region but also poses stern consequences in terms of flooding and droughts. This study analyzed the influence of Global Sea Surface Temperature Anomalies (SSTA) on occurrence of droughts in the East Asia monsoon region ($20^{\circ}N-50^{\circ}N$, $103^{\circ}E-149^{\circ}E$). Standardized Precipitation Index (SPI) was employed to characterize the droughts over the region using 30-year (1978-2007) gridded rainfall dataset at $0.5^{\circ}$ grid resolution. Due to high variability in intensity and spatial extent of monsoon rainfall the East Asia monsoon region was divided into the homogeneous rainfall zones using cluster analysis method. Seven zones were delineated that showed unique rainfall regimes over the region. The influence of SSTA was assessed by using lagged-correlation between global gridded SSTA ($0.2^{\circ}$ grid resolution) and SPI of each zone. Sea regions with potential influence on droughts in different zones were identified based on significant positive and negative correlation between SSTA and SPI with a lag period of 3-month. The results showed that SSTA have the potential to be used as predictor variables for prediction of droughts with a reasonable lead time. The findings of this study will assist to improve the drought prediction over the region.

• Ocean and Polar Research
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• 제31권1호
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• pp.11-29
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• 2009

Variability of sea surface temperature (SST) in the Japan/East Sea (JES) was studied using complex empirical orthogonal function (CEOF) analysis. Two daily data sets were analyzed: (1) New Generation 0.05o-gridded SST from Tohoku University, Japan (July 2002-July 2006), and (2) 0.25o-gridded SST from the Japan Meteorological Agency (October 1993-November 2006). Linkages with wind stress curl were revealed using 6-h 1o-gridded surface zonal and meridional winds from ancillary data of the Sea- WiFS Project, a special National Centers for Environmental Prediction/National Center for Atmospheric Research (NCEP/NCAR) product (1998-2005). SST anomalies (SSTA) were obtained by removing the seasonal signal, estimated as the leading mode of the CEOF decomposition of the original SST. Leading CEOF modes of residual SSTA obtained from both data sets were consistent with each other and were characterized by annual, semiannual, and quasi-biennial time scales estimated with 95% statistical significance. The Semiannual Mode lagged 2 months behind the increased occurrence of the anticyclonic (AC) wind stress curl over the JES. Links to dynamic processes were investigated by numerical simulations using an oceanic model. The suggested dynamic forcings of SSTA are the inflow of subtropical water into the JES through the Korea Strait, divergence in the surface layer induced by Ekman suction, meridional shifts of the Subarctic Front in the western JES, AC eddy formation, and wind-driven strengthening/weakening of large-scale currents. Events of west-east SSTA movement were identified in July-September. The SSTA moved from the northeastern JES towards the continental coast along the path of the westward branch of the Tsushima Current at a speed consistent with the advective scale.

• 해양환경안전학회지
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• 제25권6호
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• pp.678-686
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• 2019

본 연구에서는 인공위성 해수면온도 편차(Sea Surface Temperature Anomaly, SSTA)를 이용하여 한반도 연안해역의 고수온 해역을 추출하고, 국립수산과학원의 고수온속보 발령 문서와 비교하였다. 일일 SSTA 이미지를 이용하여 임계값을 적용하는 고수온 탐지 알고리즘을 제안하였으며, 고수온 주의보는 2℃ 이상, 경보는 3℃ 이상인 것으로 가정하였다. 2017~2018년 7~9월의 일평균 SST를 기반으로 한 편차자료를 사용하였으며, 고수온속보에 사용되는 지역을 대상으로 위성기반 탐지 결과를 9개 영역으로 구분하고 비교하였다. 해역별 고수온 발생 횟수 비교 결과, 수온 관측 부이가 고르게 분포한 남해 연안은 고수온속보와 위성 탐지 횟수가 유사하게 나타났다. 반면에 다른 해역은 위성 탐지 횟수가 약 2배 이상 많았으며, 이는 고수온속보 발령이 해역의 일부 위치 수온만을 고려하기 때문인 것으로 판단된다. 본 연구 결과는 향후 위성기반 연안해역 고·저수온 모니터링 체계 개발에 활용하고자 한다.

• 한국환경과학회지
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• 제4권5호
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• pp.28-28
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• 1995

The aim of the present study is to investigate the interannual variabilities of the East Asia monsoon rainfall associated with the global sea surface temperature anomaly(SSTA). For this study, the summer rainfall(from June to August) over the twenty-eight period of 1961-1988 were analyzed with being divided by nine-subregions over East Asia including Korea, China and Japan. From the analysis of the principal modes explaining the interannual variation, the interannual variabilities of summer rainfalls in South Japan and Korea are larger than those of the other subregions of the East Asia. There is a strong negative correlation between the summer rainfalls of south China and Korea. In this study, the relationship between the summer monsoon of each subregion and SSTs of the tropical NINO regions, of western Pacific warm pool, and of the subtropical ocean were investigated. The longitudinal sections of the lagged cross correlations of the summer rainfal1 anomaly in (a) Korea and (b) south China, and the monthly SSTA in the equatorial(averaged from 65 to 6N) Pacific were analyzed. The negative maximum correlation pattems of Korea''s stammer rainfal1 and SSTs over the eastern Pacific is transfered to positive maximum conrlation over central Pacific region with a biennial periodicity. In South China, the significant positive correlations are found at -12 month lag over the eastern Pacific and maximum negative correlation at 16 month lag over the central Pacific with the quasi-biennial oscillation. But the correlation coefficient reverses completely to that in Korea. In order to investigate the most prevailing interannual variability of rainfall related to the favored SSTA region, the lagged cross correlations between East Asia rainfall and SSTs over the moO regions(NINO 1+2(0-105, 90W-80W), NINO 3(5N-5S, 150W-90W), NINO 4(5N-5S, 160E-l50W) and the western Pacific worm pool (5N-5S, 120E-l60E) were analyzed. Among the lagged cross-correlation cycles in NINO regions, the maximum correlations for the negative lagged months prevail in NINO 1+2 and NINO 3, and the cross correlations for the positive lagged months NINO 4. It is noteworthy that correlation between the western Pacific warm pool SSTA and the monsoon rainfall in Korea and South China have the maximum value at negative 4 month lag. The evolution of the correlation between the East Asia monsoon rainfall and SSTA is linked to the equatorial convective cluster and related to northward propagating situation, and raising the possibility that the East Asia monsoon precipitation may be more fundamentally related to the interaction of intraseasonal oscillations and the sub-regional characteristics including the surface boundary conditions and the behavior of climatological air mass.

• 한국환경과학회지
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• 제4권5호
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• pp.413-426
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• 1995

The aim of the present study is to investigate the interannual variabilities of the East Asia monsoon rainfall associated with the global sea surface temperature anomaly(SSTA). For this study, the summer rainfall(from June to August) over the twenty-eight period of 1961-1988 were analyzed with being divided by nine-subregions over East Asia including Korea, China and Japan. From the analysis of the principal modes explaining the interannual variation, the interannual variabilities of summer rainfalls in South Japan and Korea are larger than those of the other subregions of the East Asia. There is a strong negative correlation between the summer rainfalls of south China and Korea. In this study, the relationship between the summer monsoon of each subregion and SSTs of the tropical NINO regions, of western Pacific warm pool, and of the subtropical ocean were investigated. The longitudinal sections of the lagged cross correlations of the summer rainfal1 anomaly in (a) Korea and (b) south China, and the monthly SSTA in the equatorial(averaged from 65 to 6N) Pacific were analyzed. The negative maximum correlation pattems of Korea's stammer rainfal1 and SSTs over the eastern Pacific is transfered to positive maximum conrlation over central Pacific region with a biennial periodicity. In South China, the significant positive correlations are found at -12 month lag over the eastern Pacific and maximum negative correlation at 16 month lag over the central Pacific with the quasi-biennial oscillation. But the correlation coefficient reverses completely to that in Korea. In order to investigate the most prevailing interannual variability of rainfall related to the favored SSTA region, the lagged cross correlations between East Asia rainfall and SSTs over the moO regions(NINO 1+2(0-105, 90W-80W), NINO 3(5N-5S, 150W-90W), NINO 4(5N-5S, 160E-l50W) and the western Pacific worm pool (5N-5S, 120E-l60E) were analyzed. Among the lagged cross-correlation cycles in NINO regions, the maximum correlations for the negative lagged months prevail in NINO 1+2 and NINO 3, and the cross correlations for the positive lagged months NINO 4. It is noteworthy that correlation between the western Pacific warm pool SSTA and the monsoon rainfall in Korea and South China have the maximum value at negative 4 month lag. The evolution of the correlation between the East Asia monsoon rainfall and SSTA is linked to the equatorial convective cluster and related to northward propagating situation, and raising the possibility that the East Asia monsoon precipitation may be more fundamentally related to the interaction of intraseasonal oscillations and the sub-regional characteristics including the surface boundary conditions and the behavior of climatological air mass.

• 한국토양비료학회지
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• 제33권3호
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• pp.153-159
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• 2000

토성분석방법으로 사용되고 있는 표준비중계법 (Standard Method ; SM)과 개선비중계법(Simplified for Soil Texture Analysis ; SSTA)및 간이계산법(Simplified Clay Fraction Piocedure;SCFP)간의 $2{\mu}m$ 점토함량을 비교하고자 본 시험을 수행하였다. 사용된 시료는 점토함량이 2~40% 내외의 토양 28점이었다. 현재 국내사용 표준방법은 particle size Distribution을 위한 것이지, 토성판정을 위한 $2{\mu}m$ 점토함량을 계산하는데는 약간의 문제가 있는 것으로 판단되었으며 표준분석법과의 상관을 볼 때는 개선비중계법과 간이계산법 모두 1.0에 가까운 상관계수를 보였으나, 간이계산법의 경우 표준분석 법보다는 $2{\mu}m$ 점토함량이 0~2%정도 높게 평가 되었다. 또한 분석한 시료의 토성판정결과 표준분석법과 개선비중계법은 28점 모두 동일한 결과를 얻었으나, 표준분석법과 비교할 때 간이계산법은 28점중 4점이 다른 토성으로 판정되었다. 그러므로 표준분석법 방법보다는 개선비중계법 방법이 $2{\mu}m$ 점토함량을 측정하는데 더 신속하고 정확한 방법이 될 수 있을 것으로 판단되었다.

• Ocean and Polar Research
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• 제30권3호
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• pp.313-324
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• 2008

In order to understand the variation of ENSO-related oceanic environments in the tropical and North Pacific Ocean, spatio-temporal variations of sea surface temperature anomaly (SSTA) and sea surface height anomaly (SSHA) are analyzed from distributions of complex empirical orthogonal functions (CEOF). Correlations among warm pool variation, southern oscillation index, and ocean surface currents were also examined with respect to interannual variability of the warm pool in western tropical Pacific. Spatio-temporal distributions of the first CEOF modes for SSTA and SSHA indicate that their variabilities are associated with ENSO events, which have a variance over 30% in the North Pacific. The primary reasons for their variabilities are different; SST is predominantly influenced by the change of barrier layer thickness, while SSH fluctuates with the same phase as propagation of an ENSO episode in the zonal direction. Horizontal boundary of warm pool area, which normally centered around $149^{\circ}E$ in the tropics, seemed to be expanded to the middle and eastern tropical regions by strong zonal currents through the mature phase of an ENSO episode.

• 한국지구과학회지
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• 제26권3호
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• pp.268-275
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• 2005

대표적인 엘니뇨 지수인 태평양 Nino 해역의 표층 수온을 예측하기 위해 비선형 통계모델 중의 하나인 신경망 기법을 적용하였다. 신경망 모델 학습 과정의 입력 자료로 1951년부터 1993년까지의 태평양 해역$(120^{\circ}\;E,\;20^{\circ}\;S-20^{\circ}\;N)$ NCEP/NCAR의 재분석 표층 수온 편차의 경험적 직교함수 7개 주모드를 사용하였고, 그 중 1994년부터 2003년까지의 10년 결과를 분석하였다. 모든 해역에서의 9개월까지의 신경망 모델의 예측력은 비교적 우수하였으며, 특히 1997년과 1998년의 강한 엘니뇨의 발달 및 소멸도 잘 예측함을 확인할 수 있었다. 해역별로는 Nino3 지역의 예측성능이 가장 높았으며, 9개월 이후부터는 그 예측력이 급격히 감소하였다. 한편 지역적인 영향이 커 예측력이 낮은 동태평양 연안의 Nino1+2 지역은 9개월 이후에도 예측력의 감소가 관찰되지 않았다.

• 대한전자공학회논문지SD
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• 제43권8호
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• pp.35-43
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• 2006

이 논문에서는 공정 변이의 고려를 위한 통계적 시간 분석(statistical timing analysis)에서 전력감소를 고려한 회로의 최적화를 위해 글리치 및 지연시간의 확률적 모델 및 연산을 이용하여 각 경로 및 경로상의 게이트의 민감도(sensitivity)를 계산하고 이를 이용한 사이징(sizing)을 통해 회로의 지연시간의 증가 없이 글리치를 감소하는 방법을 제시한다. 제안된 알고리즘은 통계적 시간 분석에 근거한 회로의 전후방 탐색을 이용하여 공정 변수를 고려한 확률적 글리치 발생률을 예측한다. 또한 글리치 발생률을 고려한 게이트의 선택 및 사이징 가능한 지연시간의 최적화된 계산을 통해 효율적인 게이트 사이징 기법과 글리치 감소를 위한 경로균등화 방법을 제시한다. 제안된 알고리즘의 효율성은 $0.16{\mu}m$ 모델 파라미터를 이용하여 ISCAS85 벤치마크 회로에 대한 실험을 통해 검증되었다. 실험 결과를 통해 제안된 알고리즘은 글리치 예측에 있어 8.6%의 정확도의 개선을 보였고, 경로균등화에 의한 최적화에 있어 9.5%의 개선을 보였다.