• Investigative Magnetic Resonance Imaging
• /
• v.21 no.1
• /
• pp.9-19
• /
• 2017

Background: Normalized cerebral blood volume (nCBV) can be measured using manual or semiautomatic segmentation method. However, the difference in diagnostic performance on brain tumor differentiation between differently measured nCBV has not been evaluated. Purpose: To compare the diagnostic performance of manually obtained nCBV to that of semiautomatically obtained nCBV on glioblastoma (GBM) and primary central nervous system lymphoma (PCNSL) differentiation. Materials and Methods: Histopathologically confirmed forty GBM and eleven PCNSL patients underwent 3T MR imaging with dynamic susceptibility contrast-enhanced perfusion MR imaging before any treatment or biopsy. Based on the contrast-enhanced T1-weighted imaging, the mean nCBV (mCBV) was measured using the manual method (manual mCBV), random regions of interest (ROIs) placement by the observer, or the semiautomatic segmentation method (semiautomatic mCBV). The volume of enhancing portion of the tumor was also measured during semiautomatic segmentation process. T-test, ROC curve analysis, Fisher's exact test and multivariate regression analysis were performed to compare the value and evaluate the diagnostic performance of each parameter. Results: GBM showed a higher enhancing volume (P = 0.0307), a higher manual mCBV (P = 0.018) and a higher semiautomatic mCBV (P = 0.0111) than that of the PCNSL. Semiautomatic mCBV had the highest value (0.815) for the area under the curve (AUC), however, the AUCs of the three parameters were not significantly different from each other. The semiautomatic mCBV was the best independent predictor for the GBM and PCNSL differential diagnosis according to the stepwise multiple regression analysis. Conclusion: We found that the semiautomatic mCBV could be a better predictor than the manual mCBV for the GBM and PCNSL differentiation. We believe that the semiautomatic segmentation method can contribute to the advancement of perfusion based brain tumor evaluation.

• Proceedings of the IEEK Conference
• /
• 2001.06d
• /
• pp.97-100
• /
• 2001

In this paper, We propose a new semiautomatic segmentation method using spatio-temporal similarity. In the proposed scheme, segmentation is performed using gradual region merging and hi-direction at spatio-temporal refinement. Simulation results show the efficiency of the proposed method in semantic object extraction.

• Investigative Magnetic Resonance Imaging
• /
• v.19 no.2
• /
• pp.88-98
• /
• 2015

Purpose: To compare the interobserver and intraobserver reliability of mean apparent diffusion coefficient (ADC) values using contrast-enhanced (CE) T1 weighted image (WI) and T2WI as structural images between manual and semiautomatic segmentation methods. Materials and Methods: Between January 2011 and May 2013, 28 patients who underwent brain MR with diffusion weighted image (DWI) and were pathologically confirmed as having glioblastoma participated in our study. The ADC values were measured twice in manual and semiautomatic segmentation methods using CE-T1WI and T2WI as structural images to obtain interobserver and intraobserver reliability. Moreover, intraobserver reliabilities of the different segmentation methods were assessed after subgrouping of the patients based on the MR findings. Results: Interobserver and intraobserver reliabilities were high in both manual and semiautomatic segmentation methods on CE-T1WI-based evaluation, while interobserver reliability on T2WI-based evaluation was not high enough to be used in a clinical context. The intraobserver reliability was particularly lower with the T2WI-based semiautomatic segmentation method in the subgroups with involved $lobes{\leq}2$, with partially demarcated tumor borders, poorly demarcated inner margins of the necrotic portion, and with perilesional edema. Conclusion: Both the manual and semiautomatic segmentation methods on CE-T1WI-based evaluation were clinically acceptable in the measurement of mean ADC values with high interobserver and intraobserver reliabilities.

• Genomics & Informatics
• /
• v.7 no.3
• /
• pp.168-170
• /
• 2009

The explosion in biological data resulting from high-throughput experiments requires new software tools to manipulate and display pathways in a way that can integrate disparate sources of information. A visual Java-based CAD tool for drawing and annotating biological pathways with semiautomatic image-processing features is described in this paper. The result of the image-editing process is an XML file for the appropriate links. This tool integrates the pathway images and XML file sources. The system has facilities for linking graphical objects to external databases and is capable of reproducing existing visual representations of pathway maps.

• Proceedings of the KIEE Conference
• /
• 2004.11c
• /
• pp.291-294
• /
• 2004

Semantic video object extraction is important for tracking meaningful objects in video and object-based video coding. We propose a fast semiautomatic video object extraction algorithm which combines a watershed segmentation schemes and chamfer distance transform. Initial object boundaries in the first frame are defined by a human before the tracking, and fast video object tracking can be achieved by tracking only motion-detected regions in a video frame. Experimental results shows that the boundaries of tracking video object arc close to real video object boundaries and the proposed algorithm is promising in terms of speed.

• International Journal of Railway
• /
• v.2 no.3
• /
• pp.127-130
• /
• 2009

The system improves the safety and efficiency of railway transport, combining the advanced axle-counter with single-track semiautomatic block. Using computer, to accomplish relay-based semiautomatic block logic operation and axle-counter to check section status, it will further increase the performance of railway transport. Safety-related communication is one of the important topics in railway signal system. By referring to relevant safety-related communication standards, to research on safety-related communication of Micro-computer automatic block between Railway Stations System, the thesis introduces the basic requirements, concept model, codes, and the process, etc.

• Korean Journal of Geomatics
• /
• v.1 no.1
• /
• pp.7-13
• /
• 2001

Geospatial Information Systems (GIS) have been employed to systematically manage and design land use in urban areas. This has increased the need for more accurate vector and raster data. In Korea, l/l,000-scale digital maps are used as vector data for the facility management in urban areas. This has increased the need for large scale orthoimages. Orthoimages generated from aerial imagery can provide accurate information, making possible the more effective city management. However, there is a large problem in using the orthoimages, i.e., currently available conventional orthoimages have not been generated based on Digital Elevation Model (DEM) that takes into account the building heights. So this causes the displacements of building image in large scale orthoimages. The present study is an attempt to generate the large scale orthoimages based on building DEM. The semiautomatic building extraction method can detect building outlines by mouse clicking on either building roofs or corners. Building DEM, based on the outline and calculated building height, was used to produce the large scale orthoimages with the corrected building occlusion.

• Korean Journal of Veterinary Research
• /
• v.27 no.1
• /
• pp.41-45
• /
• 1987

The present study was carried out to investigate the optimal conditions on blastogenesis of guinea pig lymphocytes. A microculture system in conjuction with a semiautomatic multiple sample harvester was used to study the in vitro optimal condition of guinea pig lymphocytes. Careful analysis of lymphocyte transformation to concanavalin A (Con A) and lipopolysaccharide (LPS) mitogen determined optimal conditions as: (a) 10% fetal bovine serum in RPMI-1640 medium (b) 48-hour culture period.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.17 no.4
• /
• pp.421-429
• /
• 1999

It is estimated that, in the twenty-first century, 70％ of global citizens will live in urban areas. This accelerated urbanization will require a greater need for the building DEM and orthoimagery along with Geographic Information System for urban management. The building DEM requires the detection of outlines showing building shapes. To do this, automatic and semiautomatic building extractions are usually used. However, in cases where automatic extraction is performed directly from the aerial images, accurate building outline extraction is very difficult because of shadow, roof color, and neighboring trees making it hard to discern building roofs. To overcome this problem semiautomatic building extraction was suggested in this paper. When a roof texture was homogeneous, building outline detection was performed by mouse-clicking on a part of the roof. To construct the building outlines when the texture was not homogeneous, a computer program was developed to search out corner points by clicking spots near corner points. The building DEM was generated by taking into account building outlines and heights calculated by image matching.

• Journal of Biomedical Engineering Research
• /
• v.28 no.6
• /
• pp.791-797
• /
• 2007

This paper proposes a semiautomatic vertebra segmentation method that overcomes limitations of both manual segmentation requiring tedious user interactions and fully automatic segmentation that is sensitive to initial conditions. The proposed method extracts fence surfaces between vertebrae, and segments a vertebra using fence-limited region growing. A fence surface is generated by a deformable model utilizing valley information in a valley emphasized Gaussian image. Fence-limited region growing segments a vertebra using gray value homogeneity and fence surfaces acting as barriers. The proposed method has been applied to ten patient data sets, and produced promising results accurately and efficiently with minimal user interaction.