• Korean Journal of Artificial Intelligence
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• v.8 no.2
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• pp.17-22
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• 2020

Purpose: After entering the 21st century, a new industrial revolution, i.e. industrial revolution 4.0, which is characterized by intelligence, automation and networking, has opened the curtain of the "industry 4.0" era. In recent years, "low-carbon economy" has been a development goal that has been paid close attention to and adhered to at home and abroad. As a major economic province, Shandong Province has not only brought about rapid economic growth, but also caused rapid environmental deterioration due to its high energy consumption, high dependence and high environmental pollution. In this environment, low-carbon economy has become an inevitable trend in the development of foreign trade in Shandong Province. Based on the current situation of foreign trade in Shandong Province and various existing problems, this paper explores the relationship between low-carbon economy and foreign trade in Shandong Province under this strategic background. Research design, data and methodology: By selecting the data from 2008 to 2017, using the carbon emission coefficient method to measure the CO2 emissions in the past decade, analyzing the impact of ecological factors on trade, selecting the most representative GDP and total imports for regression analysis, it is proved that they have a real impact on CO2 emissions. The total GDP is positively correlated with carbon emissions, while the total import is negatively correlated with carbon emissions. Results:This paper discusses the impact of low-carbon economy on foreign trade of Shandong Province from the perspective of foreign trade. Especially in today's "low-carbon economy" background. Conclusions:it is helpful for relevant departments to formulate relevant policies and promote the sustainable development of foreign trade in Shandong Province.

• Parasites, Hosts and Diseases
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• v.54 no.4
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• pp.407-414
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• 2016

Malaria remains a serious public health problem in Shandong Province, China; therefore, it is important to explore the characteristics of the current malaria prevalence situation in the province. In this study, data of malaria cases reported in Shandong during 2012-2014 were analyzed, and Plasmodium species were confirmed by smear microscopy and nested-PCR. A total of 374 malaria cases were reported, 80.8% of which were reported from 6 prefectures. Of all cases, P. falciparum was dominant (81.3%), followed by P. vivax (11.8%); P. ovale and P. malariae together accounted for 6.4% of cases. Notably, for the first time since 2012, no indigenous case had been reported in Shandong Province, a situation that continued through 2014. Total 95.2% of cases were imported from Africa. The ratio of male/female was 92.5:1, and 96.8% of cases occurred in people 20-54 years of age. Farmers or laborers represented 77.5% of cases. No significant trends of monthly pattern were found in the reported cases. All patients were in good condition after treatment, except for 3 who died. These results indicate that imported malaria has increased significantly since 2012 in Shandong Province, especially for P. falciparum, and there is an emergence of species diversity.

• Geomechanics and Engineering
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• v.19 no.6
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• pp.499-511
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• 2019

The reliability of reinforced concrete structures is frequently compromised by the deterioration caused by reinforcement corrosion. Evaluating the effect caused by reinforcement corrosion on structural behaviour of corrosion damaged concrete structures is essential for effective and reliable infrastructure management. In lifecycle management of corrosion affected reinforced concrete structures, it is difficult to correctly assess the lifecycle performance due to the uncertainties associated with structural resistance deterioration. This paper presents a stochastic deterioration modelling approach to evaluate the performance deterioration of corroded concrete structures during their service life. The flexural strength deterioration is analytically predicted on the basis of bond strength evolution caused by reinforcement corrosion, which is examined by the experimental and field data available. An assessment criterion is defined to evaluate the flexural strength deterioration for the time-dependent reliability analysis. The results from the worked examples show that the proposed approach is capable of evaluating the structural reliability of corrosion damaged concrete structures.

• Journal of Microbiology and Biotechnology
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• v.26 no.2
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• pp.241-247
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• 2016

Natamycin is a widely used antifungal antibiotic. For natamycin biosynthesis, the gene pimE encodes cholesterol oxidase, which acts as a signalling protein. To confirm the positive effect of the gene pimE on natamycin biosynthesis, an additional copy of the gene pimE was inserted into the genome of Streptomyces gilvosporeus 712 under the control of the ermE* promoter (p_ermE*) using intergeneric conjugation. Overexpression of the target protein engendered 72% and 81% increases in the natamycin production and cell productivity, respectively, compared with the control strain. Further improvement in the antibiotic production was achieved in a 1 L fermenter to 7.0 g/l, which was a 153% improvement after 120 h cultivation. Exconjugants highly expressing pimE and pimM were constructed to investigate the effects of both genes on the increase of natamycin production. However, the co-effect of pimE and pimM did not enhance the antibiotic production obviously, compared with the exconjugants highly expressing pimE only. These results suggest not only a new application of cholesterol oxidase but also a useful strategy to genetically engineer natamycin production.

• Animal Bioscience
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• v.37 no.2
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• pp.193-202
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• 2024

Objective: Oxidative stress (OS) is a pathological process arising from the excessive production of free radicals in the body. It has the potential to alter animal gene expression and cause damage to the jejunum. However, there have been few reports of changes in the expression of long noncoding RNAs (lncRNAs) in the jejunum in piglets under OS. The purpose of this research was to examine how lncRNAs in piglet jejunum change under OS. Methods: The abdominal cavities of piglets were injected with diquat (DQ) to produce OS. Raw reads were downloaded from the SRA database. RNA-seq was utilized to study the expression of lncRNAs in piglets under OS. Additionally, six randomly selected lncRNAs were verified using quantitative real-time polymerase chain reaction (qRT-PCR) to examine the mechanism of oxidative damage. Results: A total of 79 lncRNAs were differentially expressed (DE) in the treatment group compared to the negative control group. The target genes of DE lncRNAs were enriched in gene ontology (GO) terms and Kyoto encyclopedia of genes and genomes (KEGG) signaling pathways. Chemical carcinogenesis-reactive oxygen species, the Foxo signaling pathway, colorectal cancer, and the AMPK signaling pathway were all linked to OS. Conclusion: Our results demonstrated that DQ-induced OS causes differential expression of lncRNAs, laying the groundwork for future research into the processes involved in the jejunum's response to OS.

• Parasites, Hosts and Diseases
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• v.55 no.5
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• pp.555-559
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• 2017

Chigger mites are parasites of rodents and other vertebrates, invertebrates, and other arthropods, and are the only vectors of scrub typhus, in addition to other zoonoses. Therefore, investigating their distribution, diversity, and seasonal abundance is important for public health. Rodent surveillance was conducted at 6 districts in Shandong Province, northern China ($114-112^{\circ}E$, $34-38^{\circ}N$), from January to December 2011. Overall, 225/286 (78.7%) rodents captured were infested with chigger mites. A total of 451 chigger mites were identified as belonging to 5 most commonly collected species and 3 genera in 1 family. Leptotrombidium scutellare and Leptotrombidium intermedia were the most commonly collected chigger mites. L. scutellare (66.2%, 36.7%, and 49.0%) was the most frequently collected chigger mite from Apodemus agrarius, Rattus norvegicus, and Microtus fortis, respectively, whereas L. intermedia (61.5% and 63.2%) was the most frequently collected chigger mite from Cricetulus triton and Mus musculus, respectively. This study demonstrated a relatively high prevalence of chigger mites that varied seasonally in Shandong Province, China.

• Asia-Pacific Journal of Business
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• v.6 no.1
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• pp.59-82
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• 2015

According to the survey on the state of practical usage and present situation of FTAs, conducted among trade companies operating in Shandong province in 2014, more than 90% of companies are believed to be small and medium sized enterprises. Therefore this study tries to test what impact the awareness and utilization of an FTA have on its outcome among trade companies operating in Shandong province as well as partner countries and other trade companies. The research results are as follows. First, we found a positive correlation between 1) a company's global orientation (as measured in export density as a percentage of profit) and 2) its competitiveness (as measured in annual sales), and a company's degree of utilization of FTA provisions. Second, One of the findings is that the more aware of the (exporting) HS code, conventional tariffs and the process of issuing C/O the companies from Shandong province are the more they actually use (utilize) an FTA inpractice. Another interesting finding is that the more aware of the (exporting) HS code and conventional tariffs the enterprises are the higher is their practical usage level of an FTA. Third, however, at the time of this study's completion, FTA utilization was not yet positively correlated with statistically significant performance results. Therefore, to increase the utilization and performance of FTA, the China government have to make a efficient business models for each industry and support the small and mid-size businesses including Shandong province's SMEs.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1609-1614
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• 2013

Objective: To evaluate the effect of intravenous contrast on dose calculation in radiation treatment planning for oesophageal cancer. Methods: A total of 22 intravein-contrasted patients with oesophageal cancer were included. The Hounsfield unit (HU) value of the enhanced blood stream in thoracic great vessels and heart was overridden with 45 HU to simulate the non-contrast CT image, and 145 HU, 245 HU, 345 HU, and 445 HU to model the different contrast-enhanced scenarios. 1000 HU and -1000 HU were used to evaluate two non-physiologic extreme scenarios. Variation in dose distribution of the different scenarios was calculated to quantify the effect of contrast enhancement. Results: In the contrast-enhanced scenarios, the mean variation in dose for planning target volume (PTV) was less than 1.0%, and those for the total lung and spinal cord were less than 0.5%. When the HU value of the blood stream exceeded 245 the average variation exceeded 1.0% for the heart V40. In the non-physiologic extreme scenarios, the dose variation of PTV was less than 1.0%, while the dose calculations of the organs at risk were greater than 2.0%. Conclusions: The use of contrast agent does not significantly influence dose calculation of PTV, lung and spinal cord. However, it does have influence on dose accuracy for heart.

• The Korean Journal of Ecology
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• v.27 no.2
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• pp.57-60
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• 2004

There are 474 species of native vascular plant distributed in offshore islands in Shandong Province, which belong to 262 genera and 82 families. The distribution types of genera of seed plant were classified into 15 types. Temperate characteristic is dominant in the flora of offshore islands and tropical characteristic ranks secondary. Therefore, some islands play the role of stepping islands. Furthermore, 98.85% of the total genera are monotypic or bitypic which shows the offshore habitat heterogeneity in Shandong Province.

• Geomechanics and Engineering
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• v.17 no.4
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• pp.375-383
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• 2019

In underground retreating longwall coal mining, hard roof collapse is one of the most challenging safety problems for mined-out areas. Identifying precursors for hard roof collapse is of great importance for the development of warning systems related to collapse geohazards and ground control. In this case study, the Xinhe mine was chosen because it is a standard mine and the minable coal seam usually lies beneath hard strata. Real-time monitoring of hard roof collapse was performed in longwall face 5301 of the Xinhe mine using support resistance and microseismic (MS) monitoring; five hard roof collapse cases were identified. To reveal the characteristics of MS activity during hard roof collapse development and to identify its precursors, the change in MS parameters, such as MS event rate, energy release, bursting strain energy, b value and the relationships with hard roof collapse, were studied. This research indicates that some MS parameters showed irregularity before hard roof collapse. For the Xinhe coalmine, a substantial decrease in b value and a rapid increase in MS event rate were reliable hard roof collapse precursors. It is suggested that the b value has the highest predictive sensitivity, and the MS event rate has the second highest.