• Title/Summary/Keyword: Shenyang

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Seroprevalence of Toxoplasma gondii Infection in Police Dogs in Shenyang, Northeastern China

  • Liu, Cheng-Wu;Yang, Na;He, Jian-Bin;Mu, Ming-Yang;Yang, Min;Sun, Ning;Li, Hong-Kui
    • Parasites, Hosts and Diseases
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    • v.51 no.5
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    • pp.579-581
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    • 2013
  • In recent years, worldwide surveys of Toxoplasma gondii infection in dogs have been reported. However, only limited surveys of T. gondii infection in police dogs have been available, including China. In the present study, we report the seroprevalence of T. gondii in police dogs in Shenyang, northeastern China. Sera from 291 police dogs were examined for T. gondii antibodies with the modified agglutination test (MAT), and 30.9% animals were tested seropositive. The results of the present study indicated a relatively high prevalence of T. gondii infection in police dogs in Shenyang, China.

Ursolic Acid Promotes Apoptosis of SGC-7901 Gastric Cancer Cells through ROCK/PTEN Mediated Mitochondrial Translocation of Cofilin-1

  • Li, Rui;Wang, Xia;Zhang, Xiao-Hong;Chen, Hong-Hai;Liu, Yan-Dong
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9593-9597
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    • 2014
  • Ursolic acid, extracted from the traditional Chinese medicine bearberry, can induce apoptosis of gastric cancer cells. However, its pro-apoptotic mechanism still needs further investigation. More and more evidence demonstrates that mitochondrial translocation of cofilin-1 appears necessary for the regulation of apoptosis. Here, we report that ursolic acid (UA) potently induces the apoptosis of gastric cancer SGC-7901 cells. Further mechanistic studies revealed that the ROCK1/PTEN signaling pathway plays a critical role in UA-mediated mitochondrial translocation of cofilin-1 and apoptosis. These findings imply that induction of apoptosis by ursolic acid stems primarily from the activation of ROCK1 and PTEN, resulting in the translocation of cofilin-1 from cytoplasm to mitochondria, release of cytochrome c, activation of caspase-3 and caspase-9, and finally inducing apoptosis of gastric cancer SGC-7901 cells.

Prevalence of Dirofilaria immitis in Dogs in Shenyang, Northeastern China

  • Liu, Chengwu;Yang, Na;He, Jianbin;Yang, Min;Sun, Ming
    • Parasites, Hosts and Diseases
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    • v.51 no.3
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    • pp.375-377
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    • 2013
  • In the present study, we first report the seroprevalence of Dirofilaria immitis in dogs in Shenyang, northeastern China. Sera from 528 randomly selected dogs were examined for D. immitis antigen using SNAP$^{(R)}$4Dx test kit; 12.7% tested showed seropositive. No significant difference of infection was observed in different genders and breeds (P>0.05), but the difference was significant in different age groups and rearing conditions (P<0.05). The result suggested that the risk of exposure to D. immitis in dogs is high in Shenyang, and should be given attention.

Lightweight high-precision pedestrian tracking algorithm in complex occlusion scenarios

  • Qiang Gao;Zhicheng He;Xu Jia;Yinghong Xie;Xiaowei Han
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.17 no.3
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    • pp.840-860
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    • 2023
  • Aiming at the serious occlusion and slow tracking speed in pedestrian target tracking and recognition in complex scenes, a target tracking method based on improved YOLO v5 combined with Deep SORT is proposed. By merging the attention mechanism ECA-Net with the Neck part of the YOLO v5 network, using the CIoU loss function and the method of CIoU non-maximum value suppression, connecting the Deep SORT model using Shuffle Net V2 as the appearance feature extraction network to achieve lightweight and fast speed tracking and the purpose of improving tracking under occlusion. A large number of experiments show that the improved YOLO v5 increases the average precision by 1.3% compared with other algorithms. The improved tracking model, MOTA reaches 54.3% on the MOT17 pedestrian tracking data, and the tracking accuracy is 3.7% higher than the related algorithms and The model presented in this paper improves the FPS by nearly 5 on the fps indicator.

Antibacterial Constituents from Fruit Bodies of Ascomyce Bulgaria inquinans

  • Zhang Peng;Li Xian;Li Ning;Xu Jing;Li Zhan-Lin;Wang Yi;Wang Jin-Hui
    • Archives of Pharmacal Research
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    • v.28 no.8
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    • pp.889-891
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    • 2005
  • Two ergosterins and two triterpenoids were isolated from the dried fruit bodies of Ascomyce Bulgaria inquinans. By means of chemical (hydrolysis) and spectroscopic methods (NMR, EIMS), their structures were established as betuinic acid (1), cerevisterol (2), (24R)ergosta-7, $22E­diene-3\beta,\;5\alpha,\;6\beta-triol-3-O-palmitate$ (3) and ursolic acid (4). Compound 3 is a new compound.

Modal analysis and multi-objective optimization of lightweight analysis of the main beam of the concrete spreader

  • Zhang, Shiying;Song, Bo;Zhang, Ke;Chen, Hongliang;Zou, Defang;Liu, Chang;Zhu, Chunxia;Li, Dong;Yu, Wenda
    • Computers and Concrete
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    • v.28 no.5
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    • pp.465-478
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    • 2021
  • On the premise of ensuring that the static performance of the concrete spreader is met, the first-order natural frequency of the concrete spreader is increased, and the weight of the main beam is reduced. ANSYS is used as an analysis tool to perform modal analysis on the concrete spreader. The natural frequency, mode shape and modal test verification will be obtained to ensure the accuracy of finite element model analysis. Using the ANSYS designxplorer module, the size of the main beam is set, and the response surface model between the parameter variables and the optimization objective is established according to the experimental design points. Screening algorithm and MOGA algorithm are used to multi-optimize the stress, first-order natural frequency and girder weight, and the optimal solution is obtained by comparison. The results of modal analysis are consistent with those of the experiment, and a set of optimal solutions is obtained through the optimization algorithm. The optimal solution obtained can meet the purpose of increasing the first-order natural frequency of the concrete spreader and reducing the weight of the main beam under the premise of ensuring the overall dynamic and static performance of the concrete spreader.

Research Progress of the Structure Vibration-Attitude Coordinated Control of Spacecraft

  • Yang, Jingyu;Qu, Shiying;Lin, Jiahui;Liu, Zhiqi;Cui, Xuanming;Wang, Chu;Zhang, Dujiang;gu, Mingcheng;Sun, Zhongrui;Yang, Kang;Zhou, Lanwei;Chen, Guoping
    • International Journal of Aeronautical and Space Sciences
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    • v.16 no.4
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    • pp.590-601
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    • 2015
  • This paper gives an overview of research on the field of structure vibration-attitude coordinated control of spacecraft. First of all, the importance of the technology has been given an introduction, and then later the research progress of space structure dynamics modeling, research progress of structure vibration-attitude coordinated control of flexible spacecraft have been discussed respectively. Finally, future research on application of structure vibration-attitude coordinated control of spacecraft has been recommended.

A novel pattern recognition protein of the Chinese oak silkmoth, Antheraea pernyi, is involved in the pro-PO activating system

  • Wang, Xialu;Zhang, Jinghai;Chen, Ying;Ma, Youlei;Zou, Wenjun;Ding, Guoyuan;Li, Wei;Zhao, Mingyi;Wu, Chunfu;Zhang, Rong
    • BMB Reports
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    • v.46 no.7
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    • pp.358-363
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    • 2013
  • In this paper, we firstly reported a C-type lectin cDNA clone of 1029 bps from the larvae of A. Pernyi (Ap-CTL) using PCR and RACE techniques. The full-length cDNA contains an open reading frame encoding 308 amino acid residues which has two different carbohydrate-recognition domains (CRDs) arranged in tandem. To investigate the biological activities in the innate immunity, recombinant Ap-CTL was expressed in E. coli with a 6-histidine at the amino-terminus (Ap-rCTL). Besides acted as a broad-spectrum recognition protein binding to a wide range of PAMPs and microorganisms, Ap-rCTL also had the ability to recognize and trigger the agglutination of bacteria and fungi. In the proPO activation assay, Ap-rCTL specifically restored the PO activity of hemolymph blocked by anti-Ap-rCTL antibody in the presence of different PAMPs or microorganisms. In summary, Ap-rCTL plays an important role in insect innate immunity as an pattern recognition protein.

A New Triterpenoid Saponin from Pulsatilla cernua

  • Fan, Wenhao;Liu, Jianyu;Gong, Yixia;Ma, Jing;Zhou, Nan;Xu, Yongnan
    • Natural Product Sciences
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    • v.19 no.2
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    • pp.150-154
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    • 2013
  • A new oleanane-type triterpenoid saponin together with six known saponins were isolated from the roots of Pulsatilla cernua. Their structures were elucidated on the basis of spectroscopic data, including 2D NMR spectra and chemical evidence. Compounds 1 and 6 are reported from this genus for the first time.