• Title/Summary/Keyword: Susceptibility test

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The Rapid Drug Susceptibility Testing of Mycobacterium tuberculosis by GenoType$^{(R)}$ MTBDRplus in Contaminated Specimen

  • Heo, Reun;Kim, Yoon-Sik
    • Biomedical Science Letters
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    • v.19 no.4
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    • pp.330-337
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    • 2013
  • There are several methods currently being used to diagnose tuberculosis in patients, such as smear, PCR, tuberculosis culture and X-ray. For a proper medical treatment, antimicrobial susceptibility test and rapid drug susceptibility testing have been operated. Tuberculosis bacilli usually need 3~8 weeks of culture period because of delay in RNA synthesis and require 15~22 hours for generation. After a germ raises in culture, we initiated antimicrobial susceptibility test for a proper treatment. It has some difficulties to give a proper prescription for a tuberculosis patient because antimicrobial susceptibility test requires 4 weeks. To supplement this, we are practicing drug susceptibility testing which allow us to know the sensibility of RMP and INH after 2 or 3 days. But this is only possible when more than 2 positive germ. Therefore, we should practice rapid drug susceptibility testing with culture test. But if media is contaminated by other germs except Mycobacterium tuberculosis, it's hard to interpret result about culture test and to practice antimicrobial susceptibility test and rapid drug susceptibility testing. Because we have to practice again smear, culture test after extracting specimen from the patient, time is consumed and proper patient treatment is postponed. To address these problems and quick patient treatment, rapid drug susceptibility testing is practiced by using GenoType$^{(R)}$ MTDRplus method. As a result of this method we detected sensibility 10 and 7 cases and resistance 0 and 3 cases using RIM and INH respectively with other 1 case toward medicals out of the total 11 test. In conclusion rapid drug susceptibility testing can be used from the contaminated specimen after elimination of contaminated source from culture and proved that it can be practiced for rapid examination of a tuberculosis patient.

Evaluation of Frost Heave Prediction and Frost Susceptibility in Sample using JGS Test Method (일본 동상성판정기준을 적용한 시료의 동상예측 및 동상성 평가)

  • Kim, Young-Chin;Hong, Seung-Seo
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.03a
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    • pp.926-931
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    • 2008
  • This paper show two different standardized test methods(Japanese Geotechnical Society; JGS 2003). One test is a "Test Method for Frost Heave Prediction Test, JGS 0171-2003", and the other test is a "Test Method for Frost Susceptibility, JGS 0172-2003". The purpose of this test is to obtain the freezing rate(freezing speed), frost heave ratio(heave to sample height), frost heave rate(heaving speed), and other parameters to be used for frost heave prediction and determine the frost susceptibility by freezing test with water intake. This method shall be used to predict the frost heave in frozen ground and evaluate the frost susceptibility of natural and replacement materials.

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Stress Corrosion Cracking Susceptibility Evaluation by Small Punch Test (소형펀치시험법에 의한 응력부식균열 감수성평가에 관한 연구)

  • 유효선;이송인;정세희
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.17 no.8
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    • pp.2033-2042
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    • 1993
  • In conventional SCC susceptibility test, there are constant strain test, constant load test, slow strain rate test(SSRT) and K$_{ISCC}$ test. Among them, the SSRT method is much more aggressive in producing SCC than the other tests, so that the test time of it is considerably reduced. But this SSRT method has mostly been worked using the uniaxial tensile specimen untill now. Therefore, the SSRT method using the tensile specimen(Ten-SSRT) has much difficulty in SCC susceptibility evaluation of a localized region like weldment and the advantage material of high order. Recentely, the small punch(SP) test method using miniaturized small specimen is the very effective test method for fracture strength evaluation of a localized region like weldment and fusion reactor wall irradiated in the nuclear power plant. This paper investigated the possibility of SCC susceptibility evaluation by the SP-SSRT method using the miniaturized small specimen. Therefore, we obtained the result that the SP-SSRT had the possibility for the evaluations of SCC susceptibility for shorter time to corrosive environment compare to Ten-SSRT which was conventional method.

A Study on the Stress Corrosion Cracking Behaviors for Weld Joint of Steel with Various pH Values in Synthetic Sea Water (인공해수의 pH에 따른 강 용접부의 응력 부식균열거동에 관한 연구)

  • 유효선;나의균;정세희
    • Journal of Welding and Joining
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    • v.13 no.1
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    • pp.78-88
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    • 1995
  • This paper was performed to study the utility of the SP(small punch) test and the AE(acoustic emission) test in the evaluation of SCC(stress corrosion cracking) susceptibility for parent metal and bond line of HT80 steel-weld joint by SAW(submerged arc welding) with the various pH values. The loading rate used was 3*10$^{-4}$ mm/min and the corrosive environment used was synthetic sea water during the SP test and the AE test. According to the test results, the SCC susceptibility of the parent metal was increased in the order of pH6.0, pH8.2 and pH10.0. On the other hand, the bond line showed almost the same high SCC susceptibility in all pH concentrations. Synthetically, from the results of the SCC susceptibility, the macro- and micro-SEM observation, the microfracture behaviors by AE test and the relationship between SCC susceptibility and displacement at incipient failure, .delta.$_{i.f-AE}$, it can be concluded that the SP test and the AE test are the good test methods to evaluate the SCC susceptibility for parent metal and bond line of the weld joint with the change of environmental factors.

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Proposing a low-frequency radiated magnetic field susceptibility (RS101) test exemption criterion for NPPs

  • Min, Moon-Gi;Lee, Jae-Ki;Lee, Kwang-Hyun;Lee, Dongil
    • Nuclear Engineering and Technology
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    • v.51 no.4
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    • pp.1032-1036
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    • 2019
  • When the equipment which is related to safety or important to power production is installed in nuclear power plant units (NPPs), verification of equipment Electromagnetic Susceptibility (EMS) must be performed. The low-frequency radiated magnetic field susceptibility (RS101) test is one of the EMS tests specified in U.S NRC (Nuclear Regulatory Commission) Regulatory Guide (RG) 1.180 revision 1. The RS101 test verifies the ability of equipment installed in close proximity to sources of large radiated magnetic fields to withstand them. However, RG 1.180 revision 1 allows for an exemption of the low-frequency radiated magnetic susceptibility (RS101) test if the safety-related equipment will not be installed in areas with strong sources of magnetic fields. There is no specific exemption criterion in RG 1.180 revision 1. EPRI TR-102323 revision 4 specifically provides a guide that the low-frequency radiated magnetic field susceptibility (RS101) test can be conservatively exempted for equipment installed at least 1 m away from the sources of large magnetic fields (>300 A/m). But there is no exemption criterion for equipment installed within 1 m of the sources of smaller magnetic fields (<300 A/m). Since some types of equipment radiating magnetic flux are often installed near safety related equipment in an electrical equipment room (EER) and main control room (MCR), the RS101 test exemption criterion needs to be reasonably defined for the cases of installation within 1 m. There is also insufficient data regarding the strength of magnetic fields that can be used in NPPs. In order to ensure confidence in the RS101 test exemption criterion, we measured the strength of low-frequency radiated magnetic fields by distance. This study is expected to provide an insight into the RS101 test exemption criterion that meets the RG 1.180 revision 1. It also provides a margin analysis that can be used to mitigate the influence of low-frequency radiated magnetic field sources in NPPs.

Evaluation of Moisture Susceptibility of Asphalt Mixtures Using Boiling Water Test (보일링 시험을 통한 아스팔트 혼합물의 수분민감성 평가)

  • Kim, Jun;Park, Dae-Wook;Vo, Viet Hai;Kim, Hyeok-Jung;Park, Jun-Sang
    • International Journal of Highway Engineering
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    • v.17 no.1
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    • pp.77-82
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    • 2015
  • PURPOSES : The purpose of this paper is to evaluate the moisture susceptibility of asphalt mixtures containing developed liquid anti-stripping agents using the boiling water test as a screening test. METHODS : The boiling water test was used to evaluate the moisture susceptibility of asphalt mixtures containing different anti-stripping agents. The tensile strength ratio was calculated to compare the moisture susceptibility of the asphalt mixtures after indirect strength tests were performed. Additionally, image analysis techniques were used to calculate and analyze the quantity of stripped area in the asphalt mixtures. RESULTS : In general, the asphalt mixtures containing anti-stripping agents showed a higher resistance of anti-stripping based on the boiling water test and tensile strength ratio. CONCLUSIONS : The boiling water test can be used to differentiate the resistance of moisture susceptibility of asphalt mixtures, except for asphalt mixtures containing hydrated lime. The boiling water test can be used as a screening test for asphalt mixtures before conducting time consuming and expensive indirect tensile strength tests.

ANTIMICROBIAL SUSCEPTIBILITY TEST ON ORAL FLORA FROM DIFFERENT SAMPLING SITES IN CHILDREN (소아에서 구강내 정상세균총에 대한 채취부위별 항균제 감수성 차이에 관한 연구)

  • Shin, Sang-Hun;Kim, Boo-Kyoung;Song, Jung-Ho;Park, Sung-Hwan;Chung, In-Kyo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.26 no.1
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    • pp.40-44
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    • 2000
  • The most proper antibiotic must be selected after antimicrobial susceptibility test. If difference in antimicrobial susceptibility was significant between oral sampling sites, it is rationale to use the most susceptible antibiotic agent respond to dental procedure and object of treatment. This study examined sampling site variation from saliva, supragingival plaque and subgingival plaque of 16 children's oral microbes. The cultured bacterial isolates, which were Streptococcus viridans and Neisseria, were examined for 10 antimicribial drugs with the Bauer-Kirby agar disk diffusion method. The used drugs were Penicillin, Ampicillin, Oxacillin, Cephalothin, Imipenem, Gentamicin, Erythromycin, Vancomycin, Ciprofloxacin, Clindamycin. There was no significant difference between three sampling sites for antimicrobial susceptibility test of S. viridans and Neisseria and the sequence of susceptibility was agreed among them. In conclusion, it was suggested that antimicrobial susceptibility test from saliva, supragingival plaque and subgingival plaque of children have no significant sampling site variation.

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Cold Cracking Susceptibility in Weld Metal of High Strength-Toughness Steel (고강도 고인성강 용접금속의 저온균열 감수성에 관한 연구)

  • 이종봉;안상곤;안영호;김영우
    • Journal of Welding and Joining
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    • v.13 no.4
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    • pp.46-54
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    • 1995
  • The cold cracking susceptibility of a variety of weld metals deposited by GMAW with several kinds of commercial solid wires for high strength-toughness steel was investigated. G-BOP test and LB-TRC test were carried out to study the effects of preheat, chemical composition and hydrogen level on the weld metal cold cracking. The results obtained are as follows. 1) 10% CPT obtained by G-BOP test was the most valuable criteria for evaluating the cold cracking susceptibility of weld metals compared with percentage of cracking at room temperature and crack free temperature, and it had good correlation with the results of LB-TRC test. 2) Cold cracking susceptibility of weld metals was high in the row of MG100A, MG100C, MG100D and MG100B. Welds deposited with MG130 and MG80 showed similar icidents of cracking with MG100C and MG100B respectively, even though their strength levels were different. 3) Diffusible hydrogen level in weld metals which has good relation with hydrogen content in wire itself was the most critical factor for controlling the cold cracking susceptibility of weld metal.

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SOLIDIFICATION CRACKING SUSCEPTIBILITY OF

  • Yoon, Jong-Won
    • Proceedings of the KWS Conference
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    • 2002.10a
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    • pp.577-582
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    • 2002
  • The solidification cracking susceptibilities of AI-Mg-Si alloy laser welds were assessed using the self-restraint tapered specimen crack test. The cracking susceptibility of 6061 and 6082 Al-Mg-Si alloy laser welds was substantially reduced when the filler wire containing high Si such as Al-12 wt.% Si (4047A) was used. The amount of eutectic was observed to affect the solidification cracking of Al-Mg-Si alloy laser welds. Abundant eutectic seems to heal the cracking and reduces the cracking susceptibility, while an initial increase in eutectic liquid leads to the increased cracking tendency.

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Solidification Cracking Susceptibility of Al-Mg-Si Alloy Laser Welds

  • Yoon, J.W.
    • International Journal of Korean Welding Society
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    • v.2 no.2
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    • pp.42-46
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    • 2002
  • The solidification cracking susceptibilities of Al-Mg-Si alloy laser welds were assessed using the self-restraint tapered specimen crack test. The cracking susceptibility of 6061 and 6082 Al-Mg-Si alloy laser welds was substantially reduced when the filler wire containing high Si such as Al-12 wt.% Si (4047A) was used. The amount of eutectic was observed to affect the solidification cracking of Al-Mg-Si alloy laser welds. Abundant eutectic seems to heal the cracking and reduces the cracking susceptibility, while an initial increase in eutectic liquid leads to the increased cracking tendency.

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