• Genomics & Informatics
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• v.1 no.1
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• pp.32-39
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• 2003

We present a latent variable model-based approach to the analysis of gene expression patterns, coupled with topographic clustering. Aspect model, a latent variable model for dyadic data, is applied to extract latent patterns underlying complex variations of gene expression levels. Then a topographic clustering is performed to find coherent groups of genes, based on the extracted latent patterns as well as individual gene expression behaviors. Applied to cell cycle­regulated genes of the yeast Saccharomyces cerevisiae, the proposed method could discover biologically meaningful patterns related with characteristic expression behavior in particular cell cycle phases. In addition, the display of the variation in the composition of these latent patterns on the cluster map provided more facilitated interpretation of the resulting cluster structure. From this, we argue that latent variable models, coupled with topographic clustering, are a promising tool for explorative analysis of gene expression data.

• Spatial Information Research
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• v.6 no.2
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• pp.233-245
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• 1998

This study focused on developing a comprehensive strategy to revise 1:1,000 digital topographic maps for Seoul metropolitan area in terms of both organizational and technical aspects. First of all, we analyze the elements of' the revision strategy in the organization domain and produce four alternatives. Of these alternatives, we suggest a best alternative which appears to be practically sound. Secondly, we review four possible map updating methodologies, paper map digitization, a partial topographic map revision method, a method utilizing scanned aerial photographs, and a method using digital orthophotos. Through a detailed technical analysis and cost analysis of each method, we suggest a reasonable map updating method. Finally, we provide a guideline for distributing 1:1,000 digital topographic maps based on the digital map distribution policy National Geography Institute.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.31 no.1
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• pp.69-78
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• 2013

Recently, as GIS industry has substantially grown up, convergence between industries such as the application coverage of surveying and cadastral information is gradually on the increase. The new approach of convergence between topographic surveying and cadastral survey is indispensable to make the change of geospatial environment ready and to maximize the utilization of National Spatial Data Infrastructure(NSDI). The purpose of this paper is to seek the way of synergistic improvement in topographic surveying and cadastral survey in comprehensive aspects of national geospatial information. First, we reviewed policy environment to clearly establish aim of convergence and promising perspective of GIS industry policy, considering NSDI. In addition, we examined current state of administration (organization, human resource, service) and institution situation. We came up with interior ability and external policy environment as well as critical success factor for the synergistic convergence by using SWOT analysis. Lastly, we developed basic perspective of convergence and improvement model and concrete scheme for stakeholder to complementary make progress. We can come to conclusion that the convergence of topographic surveying and cadastral survey should be not only carried in macro outline of successful NSDI but also committed to completion and maintenance of GIS framework.

• Animal cells and systems
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• v.7 no.3
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• pp.237-248
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• 2003

Recent evidence on behaviors in macaque monkeys indicate that the medial temporal cortical areas such as the entorhinal cortex (EC), perirhinal cortex, and parahippocampal cortex (PHC) are importantly involved in limbic and sensory memory function. Neuroanatomical studies also have demonstrated that the medial temporal cortical areas are connected with the ventral striatum, although comparatively little is known about the precise topography of these connections. We investigated the topographic organization of connections between the medial temporal cortical areas and the ventral striatum by placing retrograde tracers into five different regions of the ventral striatum: the ventromedial caudate nucleus, ventral shell, central shell, dorsal core of the nucleus accumbens (NA), and ventrolateral putamen. We found that the shell of the NA was the main projection site from the medial temporal cortical areas. Within the shell of the NA, there were also differential connections: EC diffusely innervates shell of the NA, while the projections from the perirhinal cortex and PHC concentrate on the ventral shell of the NA. Taken together, it is possible that the ventral shell of the NA is the main integration site of the limbic and sensory memory coming from the EC, perirhinal cortex, and PHC.

• Journal of architectural history
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• v.11 no.4 s.32
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• pp.45-69
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• 2002

This study aims to find out the genetic characteristics of gridded subdivision area which has its origin from ancient local administrative city-Sangju, Jeonju, Namwon, Kwangju, Chungju. The spatial structure, based on the inter-relationship among gridded subdivision area, city wall, and topographic condition, and the morphological characteristics of gridded subdivision area are analyzed. The points of analysis on morphological characteristics of gridded subdivision area consist of the size of unit block, the organization system of unit block, the orientation of subdivision line. As a result of the analysis, three main characteristics are found. Firstly there can be found no same land subdivision rule among study areas. Secondly, the morphological features of study area were the products of cumulative process of different subdivision areas which were developed in different periods. Thirdly, the original regular gridded land subdivision seems to have been carried out in the object of a farm-land cultivation around 7th century. And there was a change of land-use from farm land to urban land-use during the later 7th century and 8th century.

• Journal of the Korean Association of Geographic Information Studies
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• v.20 no.3
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• pp.141-152
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• 2017

This paper presents a technical method for flood estimation based on satellite rainfall and satellite rainfall correction method for watersheds lacking measurement data. The study area was the Sebou Watershed, Morocco. The Integrated Flood Analysis System(IFAS) and Grid-based Rainfall-Runoff Model(GRM) were applied to estimate watershed runoff. Daily rainfall from ground gauges and satellite-derived hourly data were used. In the runoff simulation using satellite rainfall data, the composites of the daily gauge rainfall and the hourly satellite data were applied. The Shuttle Radar Topographic Mission Digital Elevation Model(SRTM DEM) with a 90m spatial resolution and 1km resolution data from Global map land cover and United States Food and Agriculture Organization(US FAO) Harmonized World Soil Database(HWSD) were used. Underestimated satellite rainfall data were calibrated using ground gauge data. The simulation results using the revised satellite rainfall data were $5,878{\sim}7,434m^3/s$ and $6,140{\sim}7,437m^3/s$ based on the IFAS and GRM, respectively. The peak discharge during flooding of Sebou River Watershed in 2009~2010 was estimated to range from $5,800m^3/s$ to $7,500m^3/s$. The flood estimations from the two hydrologic models using satellite-derived rainfall data were similar. Therefore, the calibration method using satellite rainfall suggested in this study can be applied to estimate the flood discharge of watersheds lacking observational data.

• The Korean Journal of Pain
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• v.9 no.2
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• pp.326-335
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• 1996

Background: Though a number of studies have described the distribution of substance P(SP)-like immunoreactivity in the spinal cord, they have been focused on lamina I and II of the dorsal horn and there are little morphological studies on the topographic distribution and ultrastructure of the SP immunoreactive neurons especially in the ventral horn of the spinal cord. this study was conducted to identify distribution pattern of SP immunoreactive neurons and to difine the synaptic organization of their processes in ventral horn of the thoracic cord of the cat by preembbeding immunocytochemical method using SP antiserum. Methods: Five adults cats of either sex were used and deeply anesthetized by intramuscular injection of ketamine. After removal of the spinal cord, samples of thoracic cord were taken and placed in fresh fixative at $4^{\circ}C$ for 2 hours. Transverse sections $50{\mu}m$ thick were processed using the preembbeding immunocytochemical method and incubated consecutively in the specific primary antibody and the 10% normal goat serum, the rabbit anti-substance P antiserum, the biotin-labelled goat anti-rabbit IgG and finally the avidin-biotin-peroxidase complex. The processed tissue sections were throughly washed and stained in the black with 1% uranyl acetate. Section were examined on a electron microscope. Results: 1) SP immunoreactive neurons were observed in the gray matter around central canal. 2) In lamina I and II SP immunoreactivity was observed in both myelinated and unmyelinated nerve fibers, but in ventral horn only in the unmyelinated nerve fibers. 3) SP immunoreactive axon terminals with small round and large dense core vesicles made chemical synapses onto the dendrites of motor neurons in the ventral horn. Conclusion: SP immunoreactive neurons might play an important role in modulation of motor neurons in the ventral horn of the thoracic cord of the cat.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.117-117
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• 2020

The main objective of this study was to setup model and evaluate the model performance for streamflow simulation in Burundi using Soil and Water Assessment Tool (SWAT) model. The total area of Burundi is 27,834 ㎢. The elevation of Burundi ranges from 780 m to 2,700m. The West and East are low lands, while the Central part is high land. The topographic data (30 meters Digital Elevation Model) and land use and land cover data of Burundi were obtained respectively from Shuttle Radar Topography Mission (SRTM) and the Regional Centre for Mapping of Resources for Development (RCMRD). The soil data used was obtained from Food and Agriculture Organization (FAO). The local weather data and discharge data were provided by Burundi Hydro meteorological Service (IGEBU). Mean Areal Precipitation (MAP) and Mean Areal Temperature (MAT) were estimated. The streamflow simulation was done for the period 1980-2017. The calibration and validation of river discharge was performed at a daily time step from 2005 through 2011 as the calibration period and 2012 up to 2017 as the validation period. The findings show that streamflow decreases during Jun to September and increases during March to May and October to December.

• The Korean Journal of Zoology
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• v.39 no.1
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• pp.26-35
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• 1996

The projection from the lateral reticular nucleus (LRN) to three subdivisions of the cerebellar vermal lobule VI was studied in the rat by utilizing the retrograde transport of wheatgerm agglutinin-conjugated horseradish peroxidase. Labelled neurons were located bilaterally throughout the LRN, but with ipsilateral predominance. There seemed to be a dorsal4o-ventral transition in the ipsilateral magnocellular neurons projecting to the cerebellar vermal lobules VIa-to-Vic. In the contralateral side, cells projecting to vermal lobule Via were observed at more rostral sections, whereas those projecting to lobule Vic were located at caudal sections. There were relatively few labelled neurons in parvocellular or subtrigeminal divisions at either side. Computer-aided three dimensional reconstruction of LRN projections to lobules Via/Vib or lobules Vib/Vic exhibited extensive oberlap within each combination of injection cases.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.29 no.4
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• pp.137-147
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• 2011

This study aims to find out the construction process and planning characteristics of Suwon and Hwa-sung in 18th century from the point of water system. This study has an explanatory approach. The planning intents in the water system was driven out by analyzing various planning elements in relation to water system in the process of constructing Hwa-sung in 18th century. Using Entire Map of Hwa-sung, land registration map made in 1911 and topographic map of 1/10,000 scale made in 1917, water system and interpretation of spatial structure in Hwa-sung were analyzed. The results are as follows(Planning characteristics of the water system in Haw-sung in 18th century are as follows). Firstly, in determining the spatial structure and location of Hwa-sung, water system had an important role. Secondly, integrated drainage system was planned by the organization of natural and artificial water stream. Thirdly, the main street system and land use structure were planned in relation with water system. Fourthly, territoriality of main area was planned with water stream. Fifthly, ponds were constructed for flood control and they had important role as landscape elements. Sixthly, water stream was used as intentional BiBo element. As a result of the study, the weater system of Hwa-sung in 18th century was planned by the organization of natural and artificial water stream in relation with the location of new town and wide area's spatial structure, street system, land use structure, territoriality of main area, terriflood control, water quality protection, landscape, 비보 and urban daily life.