• Archives of Pharmacal Research
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• v.26 no.11
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• pp.898-901
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• 2003

Three compounds were isolated from the stem barks of Croton robustus. Their structures were elucidated as trachyloban-19-oic, acid, trachyloban-19-ol and poilaneic acid by spectroscopic analysis. Among them, trachyloban-19-ol and methyl trachyloban-19-oate exhibited weak cytotoxic activity against gastric carcinoma and colon carcinoma with $ED_{50}$ of 9.2, 9.6 and 8.3, $9.1{\mu\textrm{g}}/mL$, respectively.