• Title/Summary/Keyword: Traditional medicine

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Proposed Mechanisms and Further study for Korean Traditional medicines-Drug Interaction in a view of Toxicology (한약의 약물상호작용 기전과 연구방향 - 독성학적인 측면을 중심으로 -)

  • Park, Yeong-Chul;Kim, Myung-Dong;Lee, Sun-Dong
    • Journal of Society of Preventive Korean Medicine
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    • v.15 no.1
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    • pp.1-16
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    • 2011
  • Objectives : The mechanisms for korean traditional medicine-drug interaction has not been well reviewed in spite that the chance for co-administration with western drugs or diet supplements has been increased. Especially, it is well known that various cytochrome P450s play a major role in drug-drug interaction. Of course, Korean traditional medicines is not excluded in a view of metabolism or biotransformation by cytochrome P450. This article was focused on reviewing the possible roles of cytochrome P450 in Korean traditional medicine-drug interaction, Also, the directions for further studies were suggested in terms of Korean traditional medicine-drug interaction. Methods : New studies for korean traditional medicine-drug interaction were reviewed and summarized in terms of cytochrome P450 activities by various Korean traditional medicines and western drugs. Results and Conclusions : Even if a few studies related to Korean traditional medicine-drug interactions was carried out, almost no studies for Korean traditional medicine-drug interactions has been found in a view of cytochrome P450. It was suggested that Korean traditional medicines and their decoction should be analyzed that how they effects on cytochrome P450, expecially CYP 1, 2, 3 families and how they interact with western drugs.

A Comparative Study of Mongolian and Korean Traditional Medicine (몽골과 한국 전통의학의 비교 연구)

  • Purevjav, Oyanga-Bileg;Ha, Won-Bae;Geum, Ji-Hye;Lee, Jung-Han
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.4
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    • pp.87-103
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    • 2021
  • Objectives The purpose of this study was to investigate the development process and describe the diagnosis methods, theories and treatments of Mongolian traditional medicine and Korean traditional medicine through literature records and prior studies. Methods Literature records and previous studies on traditional medicine of both countries were collected through various sites in Mongolia (Esan, Mongoliajol, Kok, Yumpu, Scribd, Science and Technology Foundation [STF]) and Korea (Koreanstudies Information Service System [KISS], Korea Institute of Science and Technology Information [KISTI], National Digital Science Library [NDSL], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS]). Also the English database was searched through PubMed. In the case of Mongolian traditional medicine, medical books published in Mongolia were mainly referenced and used for research. Results Studying the development process, basic concepts and the system of diagnosis and treatment of the two traditional medicine, several commonalities and differences were revealed. Conclusions This study showed that the scope of diagnosis methods between Mongolian and Korean traditional medicine were slightly different, and that the medical terminology for the diagnosis method had slightly different contents from each other. Although there were many similarities in treatments of Mongolian and Korean traditional medicine, the Chuna therapy is found in Korean traditional medicine only. The basic theories constituting traditional medicine were the same, but the five-element theory used by the two countries differs in the following two factors. Mongolia uses elements of air and space as the theory of five elements, while Korea uses elements of wood and iron.

Study on the Attitudes Toward Korean Oriental Medicine and Traditional Chinese Medicine - Based on the Responses of the University Students in Korea and China - (한의학과 중의학에 대한 수요자들의 태도연구 - 한국과 중국 대학생을 대상으로 -)

  • Lee, Hyun-Ji
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.6
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    • pp.1383-1389
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    • 2008
  • This paper investigates the attitudes of medical users toward Korean oriental medicine and traditional Chinese medicine and their future demand. The subjects are 404 university students both in Korea and in China. The items that were questioned in this paper were the attitudes toward Korean oriental medicine and traditional Chinese medicine, the experience of using the medicine, the reason they used the traditional medicine, the factors that made them satisfied with the medicine, and the future plan for using the traditional medicine. The reason the university students were selected as subjects was that they have more possibilities as future users of the traditional medicine. This paper show that Chinese students have more positive attitude toward the traditional medicine than Korean students. The Koreans' experience rate of using the traditional medicine was comparatively high and the subjects in both the countries used the western medicine for the symptoms of a cold and dental problems. For the illness of stomach, Korean and Chinese subjects used the traditional medicine and the western medicine half and half. This paper presented the subjects with the common 14 diseases that they can have and asked which medicine they will use when they have the diseases. The results of analysis indicate that the subjects tend to use different medical institution according to the diseases. The subjects in Korea and China selected different medical institution for the same disease. From the analysis of the questionnaire, it can be seen that there are some differences between Koreans and Chinese in using the medical institution, which results from the difference in medical culture and the relationship between the traditional medicine and medical users could be figured out.

A Survey on the Status of Employees of Traditional Korean Medicine Hospitals

  • Bak, Yo-Han;Huang, Dae-Sun;Shin, Hyeun-Kyoo
    • The Journal of Korean Medicine
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    • v.33 no.2
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    • pp.56-63
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    • 2012
  • Objectives: To undertake manpower-related improvements based on a comparison between specialists in the traditional Korean medicine hospitals(TKMH) and their counterparts in Western medicine Methods: A survey of the TKMH based on questionnaire sheets dispatched to them by mail(57 of 142 responded) in the June December, 2008 period, and on almanac statistics provided by the Ministry for Health, Welfare and Family Affairs of Korean Government. Results: Overall, the workforce engaged in the traditional Korean medicine hospitals comprises traditional Korean medical doctors(28%), nurses(23%), administrative staffs(19%), assistant nurses(9%), medical record keepers(2%), nutritionists(2%), herbal pharmacists(1%), and others(16%). Each hospital has 16.5 traditional Korean medical doctors on average, which can be broken down into 6.2 specialists, 1.3 generalists, and 9.3 residents/interns. Only 10.7% of whole of traditional Korean medical doctors work in the hospitals, compared to 54.5% of Western medicine doctors. The ratio of traditional Korean medical doctors to the entirety of employees in the TKMH is 2.5 times higher than their Western medicine counterparts, while the ratio of medical technicians to the entire employees in the TKMH is 20 times lower than in the Western medicine counterparts. Conclusions: To provide more qualified medical service in the TKMH, they will be required to increase the proportion of non medical doctor employees, like Western medicine counterparts.

Ginsenoside Ro, an oleanolic saponin of Panax ginseng, exerts anti-inflammatory effect by direct inhibiting toll like receptor 4 signaling pathway

  • Xu, Hong-Lin;Chen, Guang-Hong;Wu, Yu-Ting;Xie, Ling-Peng;Tan, Zhang-Bin;Liu, Bin;Fan, Hui-Jie;Chen, Hong-Mei;Huang, Gui-Qiong;Liu, Min;Zhou, Ying-Chun
    • Journal of Ginseng Research
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    • v.46 no.1
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    • pp.156-166
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    • 2022
  • Background: Panax ginseng Meyer (P. ginseng), a herb distributed in Korea, China and Japan, exerts benefits on diverse inflammatory conditions. However, the underlying mechanism and active ingredients remains largely unclear. Herein, we aimed to explore the active ingredients of P. ginseng against inflammation and elucidate underlying mechanisms. Methods: Inflammation model was constructed by lipopolysaccharide (LPS) in C57BL/6 mice and RAW264.7 macrophages. Molecular docking, molecular dynamics, surface plasmon resonance imaging (SPRi) and immunofluorescence were utilized to predict active component. Results: P. ginseng significantly inhibited LPS-induced lung injury and the expression of proinflammatory factors, including TNF-α, IL-6 and IL-1β. Additionally, P. ginseng blocked fluorescencelabeled LPS (LPS488) binding to the membranes of RAW264.7 macrophages, the phosphorylation of nuclear factor-κB (NF-κB) and mitogen-activated protein kinases (MAPKs). Furthermore, molecular docking demonstrated that ginsenoside Ro (GRo) docked into the LPS binding site of toll like receptor 4 (TLR4)/myeloid differentiation factor 2 (MD2) complex. Molecular dynamic simulations showed that the MD2-GRo binding conformation was stable. SPRi demonstrated an excellent interaction between TLR4/ MD2 complex and GRo (KD value of 1.16 × 10-9 M). GRo significantly inhibited LPS488 binding to cell membranes. Further studies showed that GRo markedly suppressed LPS-triggered lung injury, the transcription and secretion levels of TNF-α, IL-6 and IL-1β. Moreover, the phosphorylation of NF-κB and MAPKs as well as the p65 subunit nuclear translocation were inhibited by GRo dose-dependently. Conclusion: Our results suggest that GRo exerts anti-inflammation actions by direct inhibition of TLR4 signaling pathway.

The current status and future operations of Clinical Performance Evaluation (CPX) in the nationwide colleges (graduate schools) of Traditional Korean Medicine (전국 한의과대학(원)의 진료수행평가(CPX) 현황과 향후 과제)

  • Jo, Hak-jun;Min, Sung-ho
    • The Journal of Korean Medical History
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    • v.33 no.2
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    • pp.9-21
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    • 2020
  • To analyze current status of CPX in colleges of Traditional Korean Medicine nationwide and investigate the operations required for its development and distribution, we investigate current status of CPX in the nationwide colleges of Traditional Korean Medicine and suggest an improvement plan. A total of 7 colleges (graduate schools) performed CPX using the standardized patients as of July 2020 out of 13 colleges (graduate schools). Because there are a significant number of CPX modules developed by the colleges of Traditional Korean Medicine, a wide array of characteristics of Traditional Korean Medicine are covered, based on the literatures of Traditional Korean medicine. The scope of Clinical Presentation should established and a CPX module should be standardized to expand and distribute CPX in the education of Traditional Korean Medicine. If multiple colleges collect, train and manage the standardized patients in cooperation, CPX could be performed more effectively. Furthermore, medical clinical performance guide for Traditional Korean Medicine should be developed in cooperation. Greater support in the form of manpower, finance, and administration are required to distribute CPX to all colleges and develop various CPX modules.

A Study on the System of Collaborative Practice between Korean Traditional Medicine and Western Medicine for Dementia based on a Case Study (증례를 통해 본 치매의 한양방 협진 모델 연구)

  • Lee, Go-Eun;Yang, Hyun Duk;Jeon, Won Kyung;Kang, Hyung-Won
    • Journal of Oriental Neuropsychiatry
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    • v.24 no.3
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    • pp.211-228
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    • 2013
  • Objectives : This report describes the diagnostic and therapeutic procedures of Collaborative Practice between Korean Traditional Medicine and Western Medicine for two dementia patients. Furthermore, through these cases, we suggest a model of collaborative practice between Korean traditional medicine and western medicine for the treatment of dementia. Methods : Two patients suffering from several symptoms related to dementia received collaborative practice between Korean traditional medicine and western medicine. Physicians of deparment which paient first visit interviewed patient and patient's guardians, discussed the symptoms and the status of the patient. Since then, the medical team made a differential diagnosis based on the results of brain imaging, hematology, urine test. and apprehended the status of dementia by the neuropsychological test. Korean traditional physicians examined the physical symptoms and identified the pattern of dementia in Korean traditional medicine. Following this, they decided on the method of acupuncture, moxibustion, cupping and herbal treatment. Western physicians decided on the type of medication after consideration of the patient's other medical conditions. Every intervention was decided by both Korean traditional physicians and western physicians after discussion. The medical team provided education on dementia and counseled the guardians. They also wrote the paper for using the long-term care insurance for the aged. Results : Two patients showed no improvement on the neuropsychologic and activity of daily living tests. However, the patients' subjective physical symptoms were improved. The collaborative practice between Korean traditional medicine and western medicine improved the patients' and guardians' satisfaction. Conclusions : Through these cases, we propose a model of collaborative practice between Korean traditional medicine and western medicine for dementia categorized diagnosis-test, treatment, prevention, management. More specifically, we supplement qigong and psychotherapy which was inadequate in these cases.

The transition and medical system of Traditional Medicine in North Korea (북한 전통의학의 시대적 발전과정 및 의료체계)

  • Han, Chang-Hyun;Park, Sun-Hee;Shin, Mi-Suk;Choi, Sun-Mi
    • Korean Journal of Oriental Medicine
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    • v.13 no.2 s.20
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    • pp.37-45
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    • 2007
  • Background : The 'Korean Medicine' is the traditional medicine in Korea, which has preserved its homogeneous quality in the long historic period. But since 1945 when Korea was divided, the Korean Medicine has also been independently developed in South and North Korea. As a Result, it has lost its national homogeneity. Objective : In order to illuminate the past and an actuality of the transition and medical system of traditional medicine in North Korea. Method : Overview a preceding research paper and the various data of traditional medicine in North Korea. Result : 1. The name of North Korea traditional medicine from 'East medicine' was changed history with 'Korean medicine', It with the method which combines a traditional medicine and a Western medicine is endeavoring to modernization. 2. The administrative systems which take charge of the traditional medicine of North Korea are the organization which manages the Korean medicine and the Bureau of The Korean medicine production control. Also there is relation of the Bureau of the treatment prevention. 3. There are 8 medical colleges other than P'yongyang medical college. There is 6 years 6 months and 7 years 7 month follows in curriculum. Conclusions : It evaluated the past and an actuality of the transition and medical system of traditional medicine in North Korea.

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Study of Medical Devices in Traditional Korean Medical Clinics (한방의료기관 의료기기 보유 현황에 대한 조사 연구)

  • Bak, Yo-Han;Huang, Dae-Sun;Kwon, Jin-Wan;Shin, Hyeun-Kyoo
    • The Journal of Korean Medicine
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    • v.32 no.2
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    • pp.79-91
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    • 2011
  • Objectives: The purpose was to study the market of traditional Korean medical devices and survey, list and number medical devices in traditional Korean medical clinics. Methods: we researched in three ways. 1. We investigated the list of devices regarded as traditional Korean medical devices in 'Report on production, export, and import of medical devices.' 2. We investigated the statistics of medical devices equipped in traditional Korean medical clinics through the website of the Health Insurance Review & Assessment Service. 3. We surveyed medical devices in traditional Korean medical clinics by mail. Results: 1. We could not directly investigate the market for traditional Korean medical devices because they were not categorized as such ('traditional Korean medical devices'). 2. The number of medical devices in traditional Korean medical clinics has increased alongside the increase of traditional Korean medical clinics. 3. Traditional Korean medical clinics hold over 64,962 medical devices and have below 50 percent of traditional Korean medical diagnosis devices. 4. Meridian function testing machines, pulse diagnosis devices, and yangdorak showed ranking of equipment-ratio equal to ranking of insurance fees. Conclusions: Traditional Korean medical device regulations should be enacted following definitive and concrete Korean traditional medical concepts by the Korean traditional medical society.