• The Korea Journal of Herbology
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• v.29 no.5
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• pp.39-43
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• 2014

Objectives : The purpose of this sutdy was finding out the origin and daily dose of Allii Fistulosi Bulbus in Treatise on Cold Damage Diseases. Methods : In order to estimate the origin and daily dose of Allii Fistulosi Bulbus, I researched the Treatise on Cold Damage Diseases, Synopsis of Prescription of the Golden Chamber, Classified Emergency Materia Medica, Compendium of Materia Medica, and Huangdi's Internal Classic. Results : According to some important herbal textbooks, Allii Fistulosi Bulbus had no seed, was reproduced by rhizome, and its leaves were soft. Chongbaek in Treatise on Cold Damage Diseases did not include word 'raw'. The unit of the dose of it was the number of article. So Allii Fistulosi Bulbus in Treatise on Cold Damage Diseases was not Daepa but Jokpa, and was dried, and was round shaped bulb bigger than bean. The daily dose was 4, 9, 14 articles in Treatise on Cold Damage Diseases and Synopsis of Prescription of the Golden Chamber. These were estimated equal to 1, 2, 3 Ryang. 1 Ryang equals to 6.5 g in Treatise on Cold Damage Diseases, so the daily dose of Allii Fistulosi Bulbus was estimated 6.5 g, 13.0 g, and 19.5 g. I weighed the middle-sized Allii Fistulosi Bulbuses, the result was remarkably consistent with the estimated numerical value. Conclusions : In Treatise on Cold Damage Diseases, Allii Fistulosi Bulbus was dried bulb of Jokpa of Allium fistulosum Linn$\acute{e}$ and the daily dose was 4 or 9 articles, respectively equaled to 1 Ryang, 2 Ryang and 6.5 g, 13 g.

• Journal of Korean Medical classics
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• v.22 no.1
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• pp.87-91
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• 2009

"Treatise on cold damage and miscellaneous disease" is a ancient formula records on keeping in good health, provided "Internal classic" is a ancient codes on keep in good health. It can be inferred that Zhang Zhongjing was a first inheritor of academic ideology from "formula followed by establishment of the therapeutic principles". Before writing and compiling the "Treatise on cold damage and miscellaneous disease", Zhang zhongjing got the essence of "Internal classic" after composing and utilizing "Plain Questions", "Miraculous pivot and classic of difficult issues", so all the theory foundations of "Treatise on cold damage and miscellaneous disease" came from "Internal classic". The keynote of internal classic lies in obeying the Yin and Yang in natural world and preserving and maintaining the yang-qi of human body to attain the longest life-span. Zhang assimilated the essence of "Internal classic" and then generated a new ideological system - "Treatise on cold damage and miscellaneous disease" when studying it. This article is to expound ideology inheritance of keeping in good health by protecting Yang in "Internal classic" from analyzing the usage of Guizhi in "treatise on cold damage diseases".

• The Korea Journal of Herbology
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• v.32 no.1
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• pp.41-45
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• 2017

Objectives : The purpose of this study was to assume the origin and daily dose of Allii Chinensis Bulbus in Treatise on Cold Damage Diseases and Prescriptions of the Gold Chamber. Methods : I assumed the origin with Book of Materica Medica such as Illustration and Classic of Materia Medica(本草圖經), Illustration and Consideration of Plant's Name and Reality(植物名實圖考), The Korean Herbal Pharmacopoeia Forth Edition, Annotation of Hangeul Treatise of Cold Damages Diseases, and daily dose based on general principle applied on dose of Treatise on Cold Damage Diseases. Results : In Treatise on Cold Damage Diseases and Prescriptions of the Gold Chamber, the original species of Allii Chinensis Bulbus was Allium chinense G. Don. It was to be measured with weight. It was too big to write on size due to it's 10~30mm length and 3~12mm in diameter. And due to irregular size, it can't be written on number, too. Daily dose of Allii Chinensis Bulbus in Whaeyeok-san(回逆散), Gwalluhaebaekbanha-tang(栝樓薤白半夏湯) was 3 Ryang(兩), which was the most common case in Treatise on Cold Damage Diseases. And that in Gwalluhaebaekgyeji-tang(栝樓薤白桂枝湯), Gwalluhaebaekbaekju-tang(栝樓薤白白酒湯) is 8 Ryang(兩), which was the largest dose as dried herb in Treatise on Cold Damage Diseases Conclusions : The original species of Allii Chinensis Bulbus was Allium chinense G. Don. The daily dose of Allii Chinensis Bulbus was 3 Ryang(兩)(19.5g) in Whaeyeok-san and Gwalluhaebaekbanha-tang, and was 8 Ryang(兩)(52g) in Gwalluhaebaekgyeji-tang and Gwalluhaebaekbaekju-tang.

• The Journal of Korean Medical History
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• v.27 no.2
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• pp.135-143
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• 2014

Human body fluid and humor include not only sweat, joint fluid but also every fluids, for example, blood, essence, kidney essence and marrow. Historically, in the oriental medicine, there are a lot of efforts in order to preserve fluid and humor. In "Treatise on Cold Damage and Miscellaneous Disease (傷寒雜病論)", when treating cold damage, preservation of fluid and humor is put first. I tried to find out the relation about fluid and humor and pain treatment in "Treatise on Cold Damage and Miscellaneous Disease". So, I investigated sentences related to pains in "Treatise on Cold Damage and Miscellaneous Disease" "greater yang disease part" and commentaries of several chinese medical doctors. And I divide pain treatments into four categories. (fluid and humor sufficiency-exterior pattern, fluid and humor sufficiency-interior pattern, fluid and humor deficiency-exterior pattern, fluid and humor deficiency-interior pattern) At first, when treating pains of cold damage, there are many considerations about deficiency and sufficiency of fluid and humor through pulse condition and symptoms. Second, in pain-cases of fluid and humor sufficiency, purge methods is chosen. And in pain-cases of fluid and humor deficiency, tonifying methods is chosen. Finally, one of the main objects of "Treatise on Cold Damage and Miscellaneous Disease" is preservation and supply of fluid and humor.

• The Journal of Korean Medical History
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• v.27 no.2
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• pp.99-120
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• 2014

Purpose : There are two types of sleep disturbance: inability to sleep (不眠) and somnolence (多眠). This study is to examine treatments of the two types of sleep disturbance in the Books of Cold Damage and how those theories were established and formed. Methods : 1. Verses including the words related to inability to sleep and somnolence were extracted from "Treatise on Cold Damage Diseases" (傷寒論). 2. Among the Books on Cold Damages that are classified according to the symptoms, 17 books with contents related to inability to sleep and somnolence were selected to collect and classify data in three perspectives: mechanism of disease (病機), method of treatment (治法) and disease pattern (病證). 3. Data collected through the above methods were compared and diagramed. Results & Conclusions : 1. On Cold Damage, inability to sleep is mostly rooted when human body lacks yin energy while having excessive yang energy (陽盛陰虛) due to fire and heat (火熱). The reason could be misuse of perspiration inducing method (汗法) or purgation (下法) on the doctors' part. 2. On Cold Damage, somnolence is rooted when pathogen (邪氣) is spread to yin meridians (陰經) and the human body lacks yang while having excessive yin energy (陰盛陽虛) or when heat (熱邪) is invaded into interior parts (裏部). 3. Many scholars of Cold Damage in later periods had copied the "Treatise on Cold Damage Diseases" for treatments of sleep disturbance but many others have applied the verses from "Treatise on Cold Damage Diseases" or added new treatments. Do jeol-am (陶節庵) and Wang Geung-dang (王肯堂) particularly had deep understanding on "Treatise on Cold Damage Diseases" and utilized the content freely or suggested new remedies because they had thorough knowledge on relating formula as well.

• The Korea Journal of Herbology
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• v.35 no.1
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• pp.19-25
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• 2020

Objects : The daily dose of Pinelliae Tuber in ≪Treatise on Cold Damage Diseases≫ is half seung in volume, two and half ryang in weight, and fifteen in total number. But the daily dose should be a whole number. So I found out the background of this setting and correct solution. Methods : I searched Classics of Traditional Medicine, found out the background of the daily dose setting, solution. Results : The daily dose of Pinelliae tuber in ≪Hangdi's Internal Classic Miraculous Pivot≫, ≪Bohenggyuljangbuyongyakbeobyo≫ is half seung. ≪Treatise on Cold Dameage Diseases≫ followed the same daily dose of that because it referred to these books. In ≪Synopsis of Prescription of the Golden Chamber≫, the daily dose of that is half seung, one or two seung. The half seung of the Pinelliae Tuber is thirty three mL, but the diameter is 1~1.5 cm that accurate measurement by volume is difficult. The daily dose by weight is correct considering the unity of marking of the daily dose, accuracy of measurement, the fact that Pinelliae Tuber is currently distributed by cutting. So, two ryang is correct which is thirteen gram. Conclusions : Considering the traditionality, the convenience of measurement, the daily dose of Pinelliae Tuber in the ≪Treatise on Cold Damage Diseases≫ is half seung, but considering the unity, accuracy, current state of distribution, it is correct that the daily dose of it is two ryang. It corresponds to thirteen gram.

• The Korea Journal of Herbology
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• v.33 no.1
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• pp.65-70
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• 2018

Objectives : The purpose of this study was to assume the size of one piece and decocting method of Asini Corii Colla in Treatise on Cold Damage Diseases written at the Eastern han Dynasty. Methods : I assumed the size of one piece and decocting method based on Treatise on Cold Damage Diseases and Prescriptions of the Gold Chamber, Essential Skill to Benefit the People, Classified Emergency Materia Medica, Illustration and Consideration of Plant's Name and Reality, Essential Prescriptions Worth a Thousand Gold, and other articles about Asini Corii Colla. And I compared these results with current merchandize in China, Dong-e E-jiao, China Resuorces DongeEjiao, and Furen Medicine Group Co., LTD. Results : Asini Corii Colla was made of the skin of cattle in Treatise on Cold Damage Diseases written at the Eastern han Dynasty. The weight of one Asini Corii Colla is equal to 6.5 g, which is equal to one rayng of Treatise on Cold Damage Diseases. The size of it is 3.5 cm in width, 9.0 cm in length and 0.17 cm in height. The specific gravity of it was 1.24. The general daily dose was two rayng and also melted in solution. Conclusions : It was easy to measure daily dose two rayng due to weight of one Asini Corii Colla, one rayng is equal to 6.5 g, and also to melt in solution becauase of its rectangular shape and 0.17 cm thickness.

• The Korea Journal of Herbology
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• v.30 no.4
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• pp.51-55
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• 2015

Objectives : The purpose of this study was finding out the daily dose of Aconiti Lateralis Radix Preparata and Aconiti Lateralis Radix in Treatise on Cold Damage Diseases.Methods : In order to estimate the daily dose of Aconiti Lateralis Radix Preparata and Aconiti Lateralis Radix, I researched Treatise on Cold Damage Diseases, Synopsis of Prescription of the Golden Chamber, Korean Pharmacoepia 10 and Science of Contemporary Chinese Medicine Product.Results : Daily doses of Aconiti Lateralis Radix Preparata are 1, 2, or 3 pieces and those amount are respectively 1, 2, or 3 Ryang. Common dose of Aconiti Lateralis Radix Preparata is 1 piece, Maximum Dose of it is 3 Pieces and that corresponds with dose of dried herb in Treatise on Cold Damage Diseases. Consider from Sovereign, Minister, Assistant and Courier, the dose of it in Buja-tang and Whyunmu-tang is 3 Ryang. 1 Ryang corresponds with 6.5 g. Aconiti Lateralis Radix is dried without baking so its weight is equal to Aconiti Lateralis Radix Preparata. Daily doses of Aconiti Lateralis Radix are 1 piece or 1 big piece and those amount are respectively 3 or 6 Ryang. Common dose of it is 1 piece.Conclusions : From this study, in Treatise on Cold Damage Diseases, Daily Doses of Aconiti Lateralis Radix Preparata are 1, 2, or 3 pieces(19.5 g, 39 g or 52 g), and that of Aconiti Lateralis Radix are 1 piece or 1 big piece(19.5 g, 39 g). Common Dose of two Herbal Medicine is 19.5 g.

• The Korea Journal of Herbology
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• v.28 no.1
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• pp.51-58
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• 2013

Objectives : As Daily Dose of Zizyphi Fructus was designated by the numbers in Treatise on Cold Damage Disease, estimation of Daily Dose was all different among researchers. The purpose of this study was to estimate exact Daily Dose of Zizyphi Fructus. Methods : We fixed the errors in various copy of Treatise on Cold Damage Disease and considered the meaning of the Bee Zizyphi Fructus(肥大棗) and general rules of Daily Dose in Treatise on Cold Damage Disease. So we reduced Daily Dose of Zizyphi Fructus, and compared this with the standard of Zizyphy Fructus in Pharmacopoeia of several Nation and Korean Forest Service. Results : Daily Dose of Zizyphi Fructus was generally 12 pieces; less was for prescriptions which scaled down the amount of ingredients prescribed in the originals; 15, 25, and 30 pieces were used when more was required. The medicinal part was the pulp of fructus, and the dosage of 12 pieces was respectively equivalent to 3 Ryang(兩), and 19.5 g. As defined in the Korean Pharmacopoeia Ninth Edition and standards of forest products by Korea Forest Service, Zizyphi Fructus was medium-sized, and weighs about 1.625 g if properly dehydrated. Conclusions : In short, the proper Daily Dose of Zizyphi Fructus in Treatise on Cold damage Disease was 12 pieces of Zizyphi Fructus and 19.5 g of its pulp, weighing three Ryang(兩). The pulp was estimated to be 1.625 g; it was medium-sized according to the present standard.

• The Korea Journal of Herbology
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• v.36 no.1
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• pp.51-57
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• 2021

Objects : In this study, I aimed to determine the size and administration Method of pills preparation in Treatise on Cold Damage Diseases. Methods : I investigated the Treatise on Cold Damage Diseases, Newly Revised Materia Medica, Variorum of the Classic of Materia Medica, The Korean Herbal Pharmacopoeia, and recent studies. Results : There were four kinds of pills preparation. Each size of pill preparation was equal to the Odongja, Tanwhan, Yolk, and quarter of daily dosage of Decoction. One pill of Tanwhan was equivalent to 16 pills of Odongja, and one Yolk was equal to 40 pills of Odongja. The Diameter of Odongja was 6.5 mm, Tanwhan was 16.37897 mm, and Yolk was 22.11484 mm. Jeodangwhan was equal to one quarter daily dosage of Jeodangtang. Maximum size to swallow with water was Odongja and daily dosage, which was 16 pills, includes one square-inch-spoon of powder preparation. When we made the pill preparation, it is difficult to make 16 pills using one square-inch-spoon of powder. Therefore, Zhang Zhongjing made one dosage started from 10 pills to 20 pills to find out optimum dose. Due to the difficulty of making precise size of pills and considerable amount of daily dosage, there was no smaller size than Odongja. When the size of Pill preparation was larger than Odongja, it was ground or boiled slightly to make suspensions. Conclusions : These results suggest that the sizes of Pill preparation in the Treatise on Cold Damage Diseases were true compared with reality.