• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.2
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• pp.441-445
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• 2005

Tripterygium regelii has been used as an oriental medicine, especially antiparasitic, anti-inflammatory and detoxifying agents in East asia. During our research to develop new antitumor agents from natural products, MeOH ext. and CH2Cl2 ext. of Tripterygium regelii showed the potent antitumor activity. In order to purify active compounds from Tripterygium regelii, activity-guided fractionation was carried out. Silica gel and RP-18 column chromatography for the active fraction led to the isolation of two compounds and their antitumor activities were studied. Those two compounds didn't show potent antitumor activity against human tumor cell lines. The structure of two compounds were determined by $^1H-NMR$, $^{13}C-NMR$, DEPT, $^1H-^{13}C$ COSY and IR spectrum. Compound I and Compound II were turned out to be Celastrol, and ${\beta}-sitosteryl-3-o-{\beta}-D-glucopyranoside$ respectively.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.5
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• pp.1196-1199
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• 2006

Tripterygium regelii SPRAGUE is distributed in Korea and Northern China. This extract has been used as a herb medicine, especially antiparasitic, anti-inflammatory and detoxifying agent in East asia. During our research to develop new antitumor agents from natural products, Dichlorornethane (CH$_2$Cl$_2$) extract of Tripterygium regelii SPRAGUE (DTR) showed the potent apoptotic effects in A-549 lung cancer, HeLa-3 cervical cancer, SKMEL-2 melanoma cells in a dose-dependent manner. in order to purify major compounds from DTR, column chromatography was carried out gradually. Silica gel and RP-18 column chromatography for active fractions led to the isolation of a compound. The compound determined by 1 H-NMR was turned out to De Celastrol known to have antitumor activity.

• Archives of Pharmacal Research
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• v.12 no.4
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• pp.310-312
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• 1989

Three new sesquiterpene alkaloids, tripterregeline, A, B and C were isolated from the stem bark of Tripterygium regelii and their partial structures were determined by various spectroscopic methods.

• Proceedings of the Korean Society of Life Science Conference
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• 2008.10a
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• pp.77.1-77.1
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• 2008

• Journal of Korean Society of Forest Science
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• v.112 no.4
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• pp.405-416
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• 2023

In this study, the sustainability of Abies nephrolepis in the presence of Tripterygium regelii was analyzed. To accomplish this, a field survey of140 stands was conducted. Based on the presence or absence of T. regelii, as well as the layer in which it was present (where appropriate), the type of T. regelii presence wasclassified as follows: TP type, indicating the presence of T. regelii in the tree and sub-tree layers; SP type, indicating its presence in the shrub layer; and A type, indicatingits absence from all layers. The indicator species analysis revealed T. regelii to be an indicator species of the TP type and SP type. The MRPP test was used to examine the differences among the types. Moreover, the seedling and DBH class analysis indicated there to be a difficulty in terms of the status competition, as the number of young trees generated by A. nephrolepis was the lowest in the TP type. The findings of this study enhanced our understanding of the vegetation structure of A. nephrolepis, thereby contributing to efforts concerningits conservation and management.

• Journal of Korean Society of Forest Science
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• v.99 no.4
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• pp.590-596
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• 2010

To investigate and to compare the structure of Picea jezoensis forests at Chunwangbong area in the Jirisan National Park, 33 plots(400) were set up by a random sampling method. Dead individuals of Picea jezoensis trees were 15.6%, these were observed mainly in the upper-layer trees. A few seedlings of Picea jezoensis were found in this investigation area. This result indicates that Picea jezoensis might be gradually decreased in the future. Picea jezoensis stands were classified into two major groups by cluster analysis. There were strong positive correlations between Syringa reticulata and Acer pseudosieboldianum, Tripterygium regelii, Quercus serrata; Betula ermani and Lonicera maackii; Euonymus macropterus and Acer ukurunduense; Acer pseudosieboldianum and Tripterygium regelii, and relatively weak negative correlations were showed between Picea jezoensis and Abies koreana; Betula ermani and Acer ukurunduense; Acer pseudosieboldianum and Tripterygium regelii. Species diversity index(H') of investigated groups ranged from 1.0000 to 1.3010.

• Journal of Plant Biology
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• v.2 no.2
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• pp.1-21
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• 1959

1. The plant communities on Mt. Sulak, a typical alpine mountain in central Korea was researched from the standpoint of ecological survey. 2. The plant on this mountain can largely be classified into 2 categories, the warm zone (below 1100m) and the frigid zone. The former is again classified into a broad-leaved tree formation and a needle-leved tree formation, and the latter is calssified into a broad-leaved tree formation and needle-leaved tree formation, and shrub formation. 3. The broad-leaved tree formation in the warm zone can largely be classified into a Carpinus laxiflora-syringa Palibiniana var. kanibayashi association(1), a Carpinus erosa-Acer Pseudo-sieboldianun association(2), and a Quercus mongolica- Tripterygium Regelii association(3). 4. The needle-leaved tree formation in the warm zone can also largely ben classified into a Pinus densiflora- Miscanthus sinensis association(4), Abies holophylla- Tripterygium regelii association(5), Pinus kordiensis- Rhododendron schlippenbachii association(6) In the association(4), the canopy of the Pinus densiflora is gradually being occupied by the Quercus mongolica which is one kind of broad-leaved trees. 5. We can fully see a DryoPteris type of the flour layer plant type in the association (3) and also see a Sasamorpha type in the association (5). 6. The broad-leaved tree formation in the frigid zone can largely be classified into Quercus mongolica- Rhododendron schlippenbachii association (8). The constituents of tree and subtree layers in (7) and (8) associations are similar to those association (3), but the constituents of the shrub layer are different from those of associtation (3) due to the difference in height. 7. The needle-leaved formation in the frigid zone can largely be classified into Thuja koraiensisRodgersia podophylla var. viritis association (9) and Abies nephrolepis-Acer tschonoskii var. rubripes asscciation (10). The species of alpine plants or subalpine plants are gradually increased in this formation. 8. The shrub formation can also largely be classified into a Rhododendron mucronulatum- Patrinia saniculaefolia association (11) and Pinus pumila associatio (12). Association (12) has largely developed on the windy place. Association (12) was burned due to the bombing during the Korean war, but now we recoginized there occurred an invasion of Tripterygium Regelii in such a place. 9. The herb layer species which constitute the shrub formation are mostly alpine or subalpine plants of small size, and their kinds are also very few. 10. The growth of the Moss layer is especially good because of the varied conditions of the habitat. The kinds which can easily be seen are the genus of Thunidium, Haplocladium, Brachythecium, Macromitrium, Holonitrium, Atrichum, Schwstchkeopsis, Grimmia, Hedwigia, Rhynchostegium and Mnium. 11. The genus of the Sphagnum densly grows like a mat at the acid and moisturous place above 1100m. The authors should express their thanks to father. Yang Kisup, Dean of Catholic Medical College, Prof. Yoon Doksuen, from their valuable advice. Thanks arealso due to Prof. Numata, Chiba University, Prof. Takagi, Nagoya University and Prof. Ando, Hiroshima University in Japan for his kind help and identification of Bryophytes.

• Journal of the Korean Wood Science and Technology
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• v.26 no.2
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• pp.24-28
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• 1998

Ray cells with perforations are recorded for the first time in the Korean Celastraceae species of Euonymus sieboldiana and Tripterygium regelii and the Oleaceae species of Abeliophyllum distichum, Forsythia ovata, Ligustrum japonicum, and Osmanthus heterophylla, All these anomalous ray cells have simple perforations, and the vessel elements of all these species have simple perforation plates, Thus, in the Korean Celastraceae and Oleaceae, the perforations of ray cells appear to be identical with the types of perforation plates in the vessel elements of the same wood, The diagnostic value of the perforated ray cells is also discussed.

• Proceedings of the Korean Society of Life Science Conference
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• 2005.04a
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• pp.113-113
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• 2005

• Korean Journal of Environment and Ecology
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• v.10 no.2
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• pp.240-250
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• 1997

To investigate the structure and the conservation strategy of natural forest at Soch'ongbong-Taech'ongbong Area in Soraksan , 36 plots (20m*20) set up with random sampling method. Three groups - Quercus mongolica- Abies holophylla community, Acer mandshuricum- Abies nebhrolepis community, Abies holophylla-Ulmus laciniata-were classified by cluster analysis. High positive correlations were proved between Ulmus laciniata and Carpinus cordata; Tripterygium regelii and Syringa reticulata var. mandshurica ; Tripterygium regelii and Rhodo- dendron brachycarpum ; Carpinus cordata and Rhododenron mucronulatm; Wergela subsessilis and Rhododenron nucronulatum and High negative correlations were proved between Rhododen- dron schippenbachii and Euonymus macroptera; Betula ermani and Acer pseudo-sieboldianum, Tilia amurensis, Magnolia sieboldii, Betula costata ; Pinus pumila and Pinus koraiensis. Species diversity(H') of investigated area was calculated 0.8393~1.3431.