• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제20권3호
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• pp.175-202
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• 2016

Ultrasound imaging is a widely used tool for visualizing human body's internal organs and quantifying clinical parameters. Due to its advantages such as safety, non-invasiveness, portability, low cost and real-time 2D/3D imaging, diagnostic ultrasound industry has steadily grown. Since the technology advancements such as digital beam-forming, Doppler ultrasound, real-time 3D imaging and automated diagnosis techniques, there are still a lot of demands for image quality improvement, faster and accurate imaging, 3D color Doppler imaging and advanced functional imaging modes. In order to satisfy those demands, mathematics should be used properly and effectively in ultrasound imaging. Mathematics has been used commonly as mathematical modelling, numerical solutions and visualization, combined with science and engineering. In this article, we describe a brief history of ultrasound imaging, its basic principle, its applications in obstetrics/gynecology, cardiology and radiology, domestic-industrial products, contributions of mathematics and challenging issues in ultrasound imaging.

• 비파괴검사학회지
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• 제19권3호
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• pp.217-232
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• 1999

The ability to see the internal organs of the human body in a noninvasive way is a powerful diagnostic tool of modern medicine. Among these imaging modalities such as X-ray, MRI, and ultrasound. MRI and ultrasound are presenting much less risk of undesirable damage of both patient and examiner. In fact, no deleterious effects have been reported as a result of clinical examination by using MRI and ultrasound diagnostic equipment. As a result. their market volume has been rapidly increased. MRI has a good resolution. but there are a few disadvantages such as high price. non-real-time imaging capability. and expensive diagnostic cost. On the other hand, the ultrasound imaging system has inherently poor resolution as compared with X-ray and MRI. In spite of its poor resolution, the ultrasound diagnostic equipment is lower in price and has an ability of real-time imaging as compared with the others. As a result. the ultrasound imaging system has become general and essential modality for imaging the internal organs of human body. In this review various researches and developments to enhance the resolution of the ultrasound images are explained and future trends of the ultrasound imaging technology are described.

• The Journal of the Acoustical Society of Korea
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• 제29권3E호
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• pp.107-110
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• 2010

In this paper, the rationale and contents of the special issue of the Journal of the Acoustical Society of Korea regarding comprehensive reviews on past, present and future of biomedical ultrasound are described. Brief descriptions of invited articles are given, and efforts by all contributing authors are gratefully acknowledged.

• Journal of the Optical Society of Korea
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• 제18권2호
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• pp.151-155
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• 2014

Although various ophthalmic imaging methods, including fundus photography and optical coherence tomography, have been applied for effective diagnosis of ocular diseases with high spatial resolution, most of them are limited by shallow imaging penetration depth and a narrow field of view. Also, many of those imaging modalities are optimized to provide microscopic anatomical information, while functional or cellular information is lacking. Compared to other ocular imaging modalities, photoacoustic imaging can achieve relatively deep penetration depth and provide more detailed functional and cellular data based on photoacoustic signal generation from endogenous contrast agents such as hemoglobin and melanin. In this paper, array-based ultrasound and photoacoustic imaging was demonstrated to visualize pigmentation in the eye as well as overall ocular structure. Fresh porcine eyes were visualized using a real-time ultrasound micro-imaging system and an imaging probe supporting laser pulse delivery. In addition, limited photoacoustic imaging field of view was improved by an imaging probe tilting method, enabling visualization of most regions of the retina covered in the ultrasound imaging.

• 대한물리의학회지
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• 제6권3호
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• pp.303-310
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• 2011

Purpose : This study examined the feedback effect of real-time ultrasound imaging on the thickness of transversus abdominis(TrA), internal abdominal oblique(IO) and external abdominal oblique(EO) during abdominal hollowing exercise(AHE) in crook lying. Methods : We performed this study on 30 healthy men who voluntarily consented to participate in this study after listening to its purpose and method. All subject were divided into an experimental group(n=15) with using the real-time ultrasound imaging feedback(RUIF) and a control group(n=15) without the RUIF The thickness changes between rest and AHE were compared between the two groups in crook lying. Results : The difference in TrA and EO thickness changes between the groups were significant in crook lying (p<0.05). Conclusion : The group with using real-time ultrasound imaging feedback showed a higher increase in the thickness of TrA than the other group without real-time ultrasound imaging feedback. And the thickness of EO in the group with using real-time ultrasound imaging feedback decreased than the other group without real-time ultrasound imaging feedback. If the muscle thickness can be regarded as an indicator of muscle activity, RUIF will be helpful for inducing the independent activity of TrA by reducing the activities of abdominal muscles such as EO.

• 한국음향학회지
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• 제42권5호
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• pp.429-440
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• 2023

이 연구는 초음파 광학 영상 기반의 다중 모달 영상 기술에 대한 최신 연구 동향과 응용 가능성에 대해 조사하였다. 초음파 영상은 실시간 영상 기능을 가지고 있으며 인체에 상대적으로 안전한 특성으로 인해 의료 분야에서 다양한 질병의 진단에 사용되고 있다. 그러나 초음파 영상은 해상도가 낮은 한계가 있어 진단 정확도를 향상시키기 위해 다른 광학 영상과의 결합을 통한 다중 모달 영상 기술 개발 연구가 진행되고 있다. 특히 초음파 광학 영상 기반의 다중 모달 영상 기술은 각각의 영상 기법의 장점을 극대화하고 단점을 보완함으로써 질병 진단 정확도를 향상시킬 수 있는 수단으로 사용되고 있다. 이러한 기술은 초음파의 실시간 영상 기능과 광간섭 단층 영상 융합 기술, 초음파 광음향 다중 모달 영상 기술, 초음파 형광 다중 모달 영상 기술, 초음파 형광 시정수 다중 모달 영상 기술 및 초음파 분광 다중 모달 영상 기술 등 다양한 형태로 제안되고 있다. 본 연구에서는 이러한 초음파 광학 영상 기반의 다중 모달 영상 기술의 최신 연구 동향을 소개하고, 의학 및 바이오 분야에서의 응용 가능성을 조사하였다. 이를 통해 초음파와 광학 기술의 융합이 어떻게 진행되고 있는지에 대한 통찰력을 제공하고, 의료 분야에서의 진단 정확도 향상을 위한 새로운 접근 방식에 대한 기반을 마련하였다.

• 한국융합학회논문지
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• 제3권4호
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• pp.15-21
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• 2012

초음파 영상 진단 장치에서 획득한 데이터로부터 진단 객체를 추출하기 위한 영상 분할은 질병의 효과적인 진단을 위하여 필수적인 전처리 과정으로 인식되고 있으며, 지금까지 많은 분할 기법들이 연구되고 있다. 본 연구에서는 혈관 초음파 영상의 다양한 응용 및 진단법 개발을 위하여 기초 전처리과정으로서 graph cut 알고리즘에 의한 상호적인 영상분할법을 제시한다. 일반영상 및 혈관 초음파 영상에 대하여 전경(foreground)과 배경(background)의 제약조건을 주고 영상분할 처리하여, 원하는 object에 대한 분할 결과를 얻었다. 향후, 이러한 일련의 처리 과정이 실시간으로 처리되면 새로운 초음파 진단법으로 발전시켜 나갈 수 있을 것으로 사료된다.

• The Journal of the Acoustical Society of Korea
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• 제29권1E호
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• pp.1-10
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• 2010

The difference in echogenicity between cancerous and normal tissues is not quite distinguishable in ultrasound B-mode imaging. However, tumor or cancer in breast or prostate tends to be stiffer than the surrounding normal tissue. Thus, imaging the stiffness contrast between the two different tissue types is helpful for quantitative diagnosis, and such a method of imaging the elasticity of human tissue is collectively referred to as ultrasound elasticity imaging. Recently, elasticity imaging has established itself as an effective diagnostic modality in addition to ultrasound B-mode imaging. The purpose of this paper is to present various elasticity imaging methods that have been reported up to now and to describe their principles of operation and characteristics.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3555-3559
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• 2014

Background: The triple-negative breast cancer (TNBC) is an aggressive cancer characterized by the absence of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2). Preoperative mammography and ultrasound features of TNBC may potentially suggest characteristics of the disease and assist in treatment decisions. Materials and Methods: The study covered 153 patients with TNBC from May 2011 to May 2012 who were confirmed by postoperative pathology results in our hospital. We compared the radiological findings among the patients and sought to determine the significant iconographic features. The biomarkers p53 and Ki-67 are regarded as significant factors in TNBC. They were therefore used to divide the TNBC into four groups for assessment of relationships with TNBC imaging features. Results: On mammography, most TNBCs exhibit obscure (44.3%) masses. On ultrasound, the majority of masses (95.4%) were predominantly indistinct (50.7%), irregular (76.0%) or featuring posterior echo enhancement/shadowing. Color Doppler flow imaging (CDFI) emphasized hypervascular (32.9%) masses. Differences in CDFI by ultrasound among the four groups were statistically significant (p=0.009). There were obvious differences in the percentages of spiculated margin (p=0.049) and intensive posterior echo (p=0.006) with spotty flow imaging by ultrasound between the Ki-67 (+) p53 (+) and other groups. Conclusions: A combination of mammography and ultrasound revealed the imaging characteristics of TNBC included an obscure mass with less attenuated posterior echoes and some vascularity. A worse prognosis was associated with spiculated margin and intensive posterior echoes with spotty flow imaging.

• The Journal of the Acoustical Society of Korea
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• 제29권3E호
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• pp.111-118
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• 2010

Three-dimensional ultrasound imaging is a new, exciting technology that allows physicians to use ultrasound to view pathology as a volume, thereby enhancing comprehension of patient anatomy. In this paper, a brief history of the 3-D ultrasound imaging is described in accordance with the development of transducer technology. Then, two representative types of 3-D imaging transducers are reviewed with description of the concept and operation principle of each type: mechanical transducer and matrix array transducer. The mechanical transducer is detailed into free-hand scanning and sequential scanning types. Advantages of each transducer over the other and the technical issues for further performance enhancement are also presented.