• 대한토목학회논문집
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• 제34권4호
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• pp.1251-1259
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• 2014

본 연구에서는 산재되어 있는 부산항 입출항 선박의 개별 활동도(정박 접안 특성) 및 선박제원 정보를 기존 항만운영정보시스템(PORT-MIS) DB에 연계 구축하기 위한 방법론을 제시하고, 연계 구축된 3가지 DB를 이용하여 18개월(2009.01~2010.06) 동안 부산항에 입출항한 선박의 온실가스 배출량을 산정하여 그 결과를 비교 분석하였다. 본 연구에서는 선박의 기본 활동도 변수만을 포함하고 있는 저해상도의 L-PORT-MIS DB에 각 선박의 정박시간 자료를 추가하여 중해상도의 M-PORT-MIS DB를 연계 구축하였으며, 각 선박의 온실가스 배출량에 직접적인 영향을 주는 엔진출력 등과 같은 선박제원 정보를 연계시켜 고해상도의 H-PORT-MIS DB를 구축하였다. 각 활동도 DB를 이용한 선박의 온실가스 배출량 산정결과, 선박 활동도의 해상도가 높아질수록 총 온실가스 배출량은 감소하는 것으로 분석되었다. 구체적으로 저해상도 및 중해상도의 선박 활동도 자료를 이용할 경우에는 과거에 집계화된 정박 및 접안 특성에 의존하여 온실가스 배출량이 과다 산정되는 반면, 고해상도의 선박 활동도 자료를 이용할 경우에는 각 선박의 개별 접안 정박 특성과 엔진출력이 고려되는바 H-PORT-MIS DB를 이용한 선박의 온실가스 배출량은 보다 신뢰성 높은 추정치로 판단된다. 이처럼 부산항을 입출항하는 개별 선박의 특성을 반영하여 온실가스 배출량을 산정했을 경우 그 추정치는 기존 추정치와 매우 달라질 수 있어 실효성 있는 온실가스 저감대책 수립을 위해서는 본 연구에서 제안한 DB의 연계 구축이 시급하다.

• The Korean Journal of Physiology and Pharmacology
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• 제21권1호
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• pp.37-44
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• 2017

Regulation of vascular smooth muscle cell (VSMC) phenotype plays an essential role in many cardiovascular diseases. In the present study, we provide evidence that $kr{\ddot{u}}ppel$-like factor 8 (KLF8) is essential for tumor necrosis factor ${\alpha}$ ($TNF{\alpha}$)-induced phenotypic conversion of VSMC obtained from thoracic aorta from 4-week-old SD rats. Stimulation of the contractile phenotype of VSMCs with $TNF{\alpha}$ significantly reduced the VSMC marker gene expression and KLF8. The gene expression of KLF8 was blocked by $TNF{\alpha}$ stimulation in an ERK-dependent manner. The promoter region of KLF8 contained putative Sp1, KLF4, and $NF{\kappa}B$ binding sites. Myocardin significantly enhanced the promoter activity of KLF4 and KLF8. The ectopic expression of KLF4 strongly enhanced the promoter activity of KLF8. Moreover, silencing of Akt1 significantly attenuated the promoter activity of KLF8; conversely, the overexpression of Akt1 significantly enhanced the promoter activity of KLF8. The promoter activity of SMA, $SM22{\alpha}$, and KLF8 was significantly elevated in the contractile phenotype of VSMCs. The ectopic expression of KLF8 markedly enhanced the expression of SMA and $SM22{\alpha}$ concomitant with morphological changes. The overexpression of KLF8 stimulated the promoter activity of SMA. Stimulation of VSMCs with $TNF{\alpha}$ enhanced the expression of KLF5, and the promoter activity of KLF5 was markedly suppressed by KLF8 ectopic expression. Finally, the overexpression of KLF5 suppressed the promoter activity of SMA and $SM22{\alpha}$, thereby reduced the contractility in response to the stimulation of angiotensin II. These results suggest that cross-regulation of KLF family of transcription factors plays an essential role in the VSMC phenotype.

• 대한한의학원전학회지
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• 제22권4호
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• pp.217-220
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• 2009

In "Hwangjenaegyeong(黃帝內經)", the name of blood vessels is closely related to images of the river, and the word for blood vessel contains the following meaning, such as blood vessel, blood wind as well as blood stasis and so on. In a physiological perspective, the unobstructed blood vessel and normal operation blood are important symbols of health, for blood is the basis for human survival, physical activity and mental activity. In pathology, the external cold, excessive seven emotions and a biased diet can cause many kinds of abnormalities of the blood vessels, which can in turn become causes for a variety of diseases. The theory of blood vessels in "Hwangjenaegyeong" can provide guidance for diagnosis and treatment of cardiovascular diseases in practice.

• 한국CDE학회논문집
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• 제19권4호
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• pp.410-422
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• 2014

Unlike other weapon systems, a naval vessel has unique characteristics in that the vessel itself is a naval unit. In limited space, compartments with various objectives and characteristics need to be arranged, so that vessel performance is maximized. This paper studied a compartment arrangement algorithm that considers activity relationships among compartments and survivability of a vessel. Based on the study, a compartment arrangement application is developed that can generate various layout alternatives swiftly. The application developed in this study aims at automating a two dimensional compartment layout problem. A combinatorial optimization is performed with the differential evolution algorithm to achieve the optimized layout.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2019년도 춘계학술논문요약집
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• pp.275-276
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• 2019

• 생약학회지
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• 제50권1호
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• pp.25-31
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• 2019

The zebrafish (Danio rerio) is an established model organism for several pathophysiological conditions which are related to human diseases. In this study, we tested the preventive effect of eight herbal extracts, which show the inhibitory effect of advanced glycation end products (AGEs) or aldose reductase (AR) in our previous study, on high glucose (HG)-induced retinal vessel dilation in larval zebrafish and analyzed the change of hyaloid vasculature. HG-induced zebrafish hyaloid vasculatures were significantly increased in the thickness compared to untreated zebrafish (P<0.001, n=6~10). Eight herbal extracts were found to have significant retinal vessel dilation on the inhibitory activity. Particularly, Brandisia hancei (twigs and fruits), Castanopsis orthacantha (leaves and twigs), Litsea japonica (leaves and twigs), Spenceria ramalana (whole plant), and Synedrella nodiflora (leaves and stems) showed potent inhibitory activity against retinal vessel dilation in HG-induced larval zebrafish.

• 수산해양기술연구
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• 제59권1호
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• pp.74-84
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• 2023

This paper is the result of a comparative analysis of crew members' workloads using the EMG and OWAS methods according to the fishing process before and after the improvement of the operating system of the experimental vessel, with the aim of improving operational efficiency and safety work of coastal improved stow net fishing vessels. The target crew members were three people with at least five years of experience on board the same fishing vessel as the experimental vessel. After improving the operating system, such as installing a power block crane and two capstans, change the location of the ball-roller, the time required for setting and hauling work decreased (p < .01), and the evaluation results by OWAS showed that the overall workload for setting and hauling net work decreased. The results of muscle activity analysis showed a decrease in lashing anchor work (p < .01) in the case of hauling net and in anchor dropping work in the case of setting net (p < .001). It is judged that the use of ball rollers in net handling has been reduced; consequently, work safety has been improved.

• 한국항해학회지
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• 제22권2호
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• pp.81-87
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• 1998

On this paper, the methods of optimization research of the fishing navigation using the graph theory are substantiated on the basis of the proposed probable model of the fishing vessel navigator's activity. The graph theory is concered about the transitionform the top graph to the rib one. And the definition of the additional system elements (quasi elements) necessary to provide the effectiveness during the fishing navigation are also substantiated herein. This approach helps to optimize the structure of any fishing vessel monitoring system.

• 한국산학기술학회논문지
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• 제3권1호
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• pp.44-48
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• 2002

음식물을 장기 저장하기 위해서는 각 음식물에 적합한 온도에서 저장하여야 하는데, 우리 식생활에서 필수적인 김치의 최적 저장 온도는 0∼5℃이다. 김치의 신선도를 유지하기 위해서는 저장 온도뿐만 아니라 김치의 숙성에 필요한 미생물을 조절하기 위한 용기의 재질도 중요한 요인으로 작용한다. 본 연구에서는 김치내의 미생물 활동에 최적의 조건을 유지할 수 있는 토기 용기를 이용한 저장고를 개발하여 기존의 상용화된 제품과 특성을 비교 분석하였다.

• Nuclear Engineering and Technology
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• 제51권1호
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• pp.125-137
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• 2019

The purpose of this paper is to study the source term behavior after severe accidents by using a semi-kinetic model for simulation and calculation of in-containment activity. The reactor containment specification and the safety features of the containment under different accident conditions play a great role in evaluating the in-containment activity. Assuming in-vessel and instantaneous release of radioactivity into the containment, the behavior of in-containment isotopic activity is studied for noble gasses (Kr and Xe) and the more volatile elements of iodine, cesium, and aerosols such as Te, Rb and Sr as illustrative examples of source term release under LOCA conditions. The results of the activity removal mechanisms indicates that the impact of volumetric leakage rate for noble gasses is important during the accident, while the influence of deposition on the containment surfaces for cesium, mainly iodine isotopes and aerosol has the largest contribution in removal of activity during evolution of the accident.