• Journal of the Society of Naval Architects of Korea
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• v.48 no.6
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• pp.552-559
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• 2011

An interest in Arbitrary Lagrangian Eulerian (ALE) finite element methods has been increased due to more accurate responses in Fluid-Structure Interaction(FSI) problems. The multi-material ALE approach was applied to the prediction of the acceleration response of free-fall lifeboat, and its responses were compared to those of the single-material ALE one. It could be found that even though there was no big difference in the simulation responses of two methods, the single-material and multi-material ALE ones, the latter multi-material ALE method showed a little bit more close response to those of experimental results compared to the former single-material ALE one, especially in the x- and z-direction acceleration responses. Through this study, it could be found that several parameters in the ALE algorithms have to be examined more carefully for a good structural safety assessment of FSI problems.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.12 no.10
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• pp.1759-1766
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• 2008

RFID middleware is the system software that converts EPC data collected from RFID reader devices into meaningful data, that users want, and transfers the result to the users with a variety of protocols. ALE specification, the RFID middleware specification proposed by EPCglobal that is a leading group of do facto international standards with respect to RFID, can handle only EPC code. Meanwhile, a new code system which is called KKR was proposed by NIDA in order to represent RFID tag data in a specific manner and cultivate the domestic RFID industry. In this case, the existing RFID middleware can not process KKR code system because of inherent attributes of the system. In this paper, we proposed a method of KKR code conversion to properly process KKR code in ALE middieware, implemented our method in real, and adopted it into existing ALE middleware. Also, we proposed a new URN format for RFID tag data to manipulate KKR code in ALE middleware. By using the proposed method, the existing ALE middleware conforming to international specification can handle KKR code effectively, and the integration among RFID middleware and legacy systems can be easily supported also.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.21 no.11
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• pp.1912-1920
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• 1997

In the analysis of metal forming process, ALE(Arbitrary Lagrangian Eulerian) finite element methods have been increasingly used for the capability to control mesh independently from material flow. The methods can be divided into two groups i.e., coupled and split formulations. In the present work, the split ALE formulation is used for computational efficiency. A split ALE finite element method developed for rigid-viscoplastic materials and applied to the analysis of hot square die extrusion. Since thermal state greatly affects the product quality, an ALE scheme for temperature analysis is also presented. As computational examples, profile shapes as square and cross-like sections are chosen.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2006.04a
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• pp.381-388
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• 2006

A porous medium is composed of solids, fluids, and gas which have different physical and chemical properties. In addition, these constituents have a relative velocity between each other. So far, in order to analyze porous media using finite element method, Lagrangian or Eulerian method has been used. However, the numerical analyses for porous media have a defect that the methods do not describe the movements of constituents. In this paper, numerical analysis for unsaturated porous media was performed in frame of ALE method which has advantages of Lagrangian and Eulerian. Namely, the Lagrangian description was used in solid phase, and the Eulerian description was used in fluid or gas phase in a porous medium Then the relationship between each other was controlled by the convective term in ALE method. Finally, the numerical results of ALE were compared with tile results of Lagrangian analysis.

• Journal of the Korean GEO-environmental Society
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• v.4 no.1
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• pp.5-10
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• 2003

The solids and the fluids in porous media have a relative velocity to each other. Due to physically and chemically different material properties and their relative velocity, the behavior of saturated porous media is extremely complicated. Thus, in order to describe and clarify the deformation behavior of saturated porous media, constitutive models for deformation of porous media coupling several effects need to be developed in frame of Arbitrary Lagrangian Eulerian(ALE) description. The aim of ALE formulations is to maximize the advantages of Lagrangian and Eulerian elements, and to minimize the disadvantages. Therefore, this method is appropriate for the analysis of porous media which are considered for the behavior of the solids and the fluids. For this reason, mass balance equations for saturated porous media are derived here in ALE description frames. ALE formulations of mass conservation for the solid phase and the fluid phase are expressed. Then, linear momentum balance equation for porous media as multiphase media is expressed.

• Nutrition Research and Practice
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• v.15 no.5
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• pp.555-567
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• 2021

BACKGROUND/OBJECTIVES: Abeliophyllum distichum is a plant endemic to Korea, containing several beneficial natural compounds. This study investigated the effect of A. distichum leaf extract (ALE) on adipocyte differentiation. MATERIALS/METHODS: The cytotoxic effect of ALE was analyzed using cell viability assay. 3T3-L1 preadipocytes were differentiated using induction media in the presence or absence of ALE. Lipid accumulation was confirmed using Oil Red O staining. The mRNA expression of adipogenic markers was measured using RT-PCR, and the protein expressions of mitogen-activated protein kinase (MAPK) and peroxisome proliferator-activated receptor gamma (PPAR𝛾) were measured using western blot. Cell proliferation was measured by calculating the incorporation of Bromodeoxyuridine (BrdU) into DNA. RESULTS: ALE reduced lipid accumulation in differentiated adipocytes, as indicated by Oil Red O staining and triglyceride assays. Treatment with ALE decreased the gene expression of adipogenic markers such as Ppar𝛾, CCAAT/enhancer binding protein alpha (C/ebp𝛼), lipoprotein lipase, adipocyte protein-2, acetyl-CoA carboxylase, and fatty acid synthase. Also, the protein expression of PPAR𝛄 was reduced by ALE. Treating the cells with ALE at different time points revealed that the inhibitory effect of ALE on adipogenesis is higher in the early period treatment than in the terminal period. Furthermore, ALE inhibited adipocyte differentiation by reducing the early phase of adipogenesis and mitotic clonal expansion. This was indicated by the lower number of cells in the Synthesis phase of the cell cycle (labeled using BrdU assay) and a decrease in the expression of early adipogenic transcription factors such as C/ebp𝛽 and C/ebp𝛿. ALE suppressed the phosphorylation of MAPK, confirming that the effect of ALE was through the suppression of early phase of adipogenesis. CONCLUSIONS: Altogether, the results of the present study revealed that ALE inhibits lipid accumulation and may be a potential agent for managing obesity.

• Journal of the Korean Chemical Society
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• v.60 no.1
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• pp.69-81
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• 2016

The purpose of this study was to find out the validation of instructional strategies using the Advanced Laboratory Equipment (ALE class) by investigating science high school students’ perception on ALE in chemistry classrooms and to consider the need for development of teaching materials on ALE class. 7 sessions of ALE including experiments with innovative equipment were developed and applied to 21 students in D Science High School. At the end of the sessions, questionnaire was given to the students. We also collected qualitative data by interviewing 9 students who participated in the questionnaire. We analyzed the data collected by In-depth interviews and students’ experimental reports. The result showed that ALE class was effective to enhance students’ understanding of learning concepts because the experimental time was shortened in real time data processing. Some students showed creative performance on solving scientific problems by using everyday materials in experimental process and developed perceptions of practical inquiry. Through this process, students’ positive attitudes and interests in science and heuristic inquiry skills were also enhanced. Developing ALE lesson materials will be helpful for students to understand science and technology and the domain of science in broader contexts.

• Proceedings of the IEEK Conference
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• 2001.09a
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• pp.95-98
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• 2001

The adaptive line enhancer (ALE) is widely used for enhancing narrowband signals corrupted by broadband noise. In this paper, we propose novel ALE methods to improve the enhancing capability. The proposed methods are motivated by the fact that the output of the ALE is a fine estimate of the desired narrowband signal with the broadband noise component suppressed. The proposed methods preprocess the input signal using ALE filter to regenerate a finer input signal. Thus the proposed ALE is driven by the input signal with higher signal-to-noise ratio (SNR). The analysis and simulation results are presented to demonstrate that the proposed ALE has better performance than conventional ALE´s.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.4
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• pp.648-655
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• 2007

Nowadays, to realize ubiquitous computing environment, many research activities have been going on within various kinds of research domains including automatic identification sensor network, home network, telematics and so on. Especially, RFID middleware that supports the aggregation of RFID tag data, control and management, and the integration with legacy systems has recently gained a lot of attention. Meanwhile, EPCglobal defined an ALE(Application Level Events) standard specification, which exists between RFID readers and applications, and substitutes the previous systems called Savant. In the specification internal structures and implementation technologies of ALE are not mentioned and only external interfaces are defined. This approach easies the verification of standard compliance and inter-operability of the layer. In this paper, we present the design of ALE-compliant RFID middleware systems that process RFID tag data efficiently.

• Journal of Microbiology and Biotechnology
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• v.30 no.6
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• pp.793-803
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• 2020

Adaptive laboratory evolution (ALE) is an evolutionary engineering approach in artificial conditions that improves organisms through the imitation of natural evolution. Due to the development of multi-level omics technologies in recent decades, ALE can be performed for various purposes at the laboratory level. This review delineates the basics of the experimental design of ALE based on several ALE studies of industrial microbial strains and updates current strategies combined with progressed metabolic engineering, in silico modeling and automation to maximize the evolution efficiency. Moreover, the review sheds light on the applicability of ALE as a strain development approach that complies with non-recombinant preferences in various food industries. Overall, recent progress in the utilization of ALE for strain development leading to successful industrialization is discussed.