• Title/Summary/Keyword: anchovy cooking discards

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Angiotensin Converting Enzyme Inhibitory Activity in Peptic Hydrolysates of Cooking Discards from Anchovy Factory Ship (멸치 가공선 자숙폐액 Pepsin 가수분해물의 Angiotensin 전환효소 저해작용)

  • Ji, Cheong-Il;Lee, Ji-Hye;Park, Douck-Choun;Gu, Yeun-Suk;Kim, In-Soo;Lee, Tae-Gee;Jung, Kyoo-Jin;Park, Yeung-Ho;Kim, Seon-Bong
    • Korean Journal of Food Science and Technology
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    • v.34 no.3
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    • pp.529-532
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    • 2002
  • The angiotensin converting enzyme (ACE) inhibitory activity in peptic hydrolysate of raw anchovy cooking discards was 51.3% at 1 mg of protein per $100\;{\mu}L$ sample solution. While, after the treatment of pepsin for 4 h, was 65.8%. The crude peptides fractionated through Bio-gel P-2 column chromatography consisted of five fractions $({P-1}{\sim}{P-5})$ and had maximum inhibitory activity in the fraction P-2 ($IC_{50}$=0.319 mg protein/mL). The fraction P-2 was rich in aspartic acid, glutamic acid, and glycine.