• Title, Summary, Keyword: antimicrobial

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Antimicrobial Characterictics of Antimicrobial Agent (Antibiotics) and Reduction Effect on Mal-ordour. (항균제의 항균특성 및 악취제거 효과)

  • Shin, Choon-Hwan;Kim, Jong-Hyun;Han, Sun-Hong
    • Journal of Environmental Science International
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    • v.3 no.2
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    • pp.157-164
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    • 1994
  • Various antimicrobial agents are widely used for the purpose of antimicrobial process. We investigated antimicrobial activity and reduction efficiency of mal-ordour by the diphenyl ether compound (2,4,4'- trichloro -2'- hydroxy diphenyl ether) against Sraphylocom aureus(S.aureus and Proton vulgaris(p.vulgaris causing the mal-ordour, Especially, the diphenyl ether compound is not restricted to the regulation of water-contamination. In this research, we found that the optimum concentration of diphenyl ether compound was 1.5w% for both strains and antimicrobial expressions were c0.38t= 2.56 for S.aureus, c0.38t=2.67 for P.vulgaris. We found also that -OH group played the role of antimicrobial functional group. Lastly, reduction effect of mal-ordour was more than 90% for both strain at the optimum conditions. Key Words : antimicrobial agents, antimicrobial activity, reduction effect of mal-ordour, antimicrobial expression, antimicrobial functional group.

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Antimicrobial Properties of Paper Treated with Acidic Liquid from Carbonized Rice Hull (왕겨초액 처리지의 항균 특성)

  • Min, Choon-Ki;Jo, Joong-Yeon;Shin, Jun-Sub;Lee, Se-Eun
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.43 no.2
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    • pp.72-76
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    • 2011
  • Antimicrobial activities of the Acidic Liquid originated from Carbonized Rice Hull(ALCRH) and the paper treated with ALCRH were investigated to apply ALCRH to functional paper products as a natural antimicrobial agent. ALCRH showed antimicrobial activity for bacteria and yeast, with higher performance for bacteria than for yeast. Antimicrobial activity was not developed on paper coated with ALCRH by bar coater probably due to the evaporation of antimicrobial compounds of ALCRH from the paper surface with time. Saturation of paper with ALCRH was essential to develop antimicrobial activity on the paper. Dipping paper in ALCRH solution was recommended as one of the effective ways to make antimicrobial paper.

Isolation and Antimicrobial Activity of Antimicrobial Substance Obtained from Leaf Mustard(Brassica juncea) (갓(Brassica juncea)의 항균물질의 분리 및 항균성)

  • 강성구
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.5
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    • pp.695-701
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    • 1995
  • The ethanol extract of leaf mustard(Brassica juncea) exhibiting high antimicrobial activities was fractionated in the order of hexane, chloroform, ethylacetate and butanol fractions to test antimicrobial activity. The highest antimicrobial activity for the bacteria tested was found in the ethylacetate fraction, but a lesser extent in the butanol fraction. In contrast to antimicrobial activity for the bacteria, both ethylacetate and butanol fractions showed weak antimicrobial activity for yeasts. Unknown compound A in the ethylacetate fraction which exhibited a strong antimicrobial activity was isolated by silica gel column chromatography and HPLC, and exhibited 9 times more antimicrobial activity than the ethylacetate fraction.

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Isolation of Antimicrobial Substance from the Korean Traditional Leaf Mustard, Brassica juncea Coss.

  • Kang Seong-Koo
    • Plant Resources
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    • v.8 no.2
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    • pp.145-154
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    • 2005
  • The antimicrobial effect of each fraction after fractionation of an ethanol extract of leaf mustard was examined in terms of nucleic acid, chloroform, ethylacetate, and butanol. The ethylacetate fraction, which showed the strongest level of antimicrobial effect among the different ethanol extract fractions of leaf mustard, was isolated and purified using silica gel column chromatography and HPLC, respectively, to obtain a single antimicrobial substance called KLM-1. The antimicrobial effect of this substance was 10 times higher than that of the ethylacetate fraction. A further study is on the way to confirm the structure of the antimicrobial substance KLM-1 through LC/Mass and NMR.

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Natural Antibiotics: Antimicrobial Peptides (천혜의 항생제: 항균펩티드)

  • Kim, Yeon-Sook;Kim, Jeong-Jae;Choi, Young-Nim
    • The Journal of the Korean dental association
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    • v.41 no.2
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    • pp.116-123
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    • 2003
  • Antimicrobial Peptides are natural antibiotics evolved by many plants, invertebrate, and vertebrate to defend against the microbial infection. Antimicrobial peptides show a broad-spectrum antimicrobial activity with little opportunity for the development of resistance since they target microbial membranes that distinguish microbes from enkaryotic cells. The oral cavity is constantly exposed to microbial challenges and antimicrobial peptides play an important role in managing the oral health. With the increase of resistant micro-organisms to conventional antibiotics, antimicrobial peptides are attracting interests as novel antibiotics. In this review, the characteristics of antimicrobial of antimicrobial peptides including the classification, mechanism of action, resistance, and expression in the oral cavity have been discussed in the prospects of application to oral disease.

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Purification of Antimicrobial Substance for the Extract from the Root Bark of Morus alba (상백피 추출물로부터 향균성 물질의 분리정제)

  • 박욱연;김신희;김지회;김용관;장동석
    • Journal of Food Hygiene and Safety
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    • v.10 no.4
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    • pp.225.1-230
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    • 1995
  • The ethanol extract from the root bark of Morus alba showed the strongest antimicrobial activity on the growth of almost all the tested microorganisms which were food-borne pathogens and food-related microorganisms. 1) In order to isolate and purify of antimicrobial substance extracted from the root bark of Morus alba, the antimicrobial substance from the ethanol extract which exhibited a strong antimicrobial activity was purified by solvent fractionation, silica gel column chromatography, TLC and HPLC. Among the fractions fractionated by 4 kind of solvents from the ethanol extract, the antimicrobial activity of ethyl acetate fraction had the strongest antimicrobial activity against B. subtilis. Unknown compound were isolated from the ethyl acetate fraction by silica gel column chromatography, TLC and HPLC and the compounds showed strong absorbance at 207, 217 and 285 nm, therefore, it was supposed to be a kinds of aromatic compound.

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Antimicrobial Activities of Extracts of Camellia sinensis (L.) O. Kuntze and Profile of Antimicrobial Agents Resistance for Carbapenem-Resistant Enterobacteriaceae

  • Yum, Jong Hwa
    • Biomedical Science Letters
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    • v.25 no.3
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    • pp.288-292
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    • 2019
  • In vitro antimicrobial activities of hot water extracts of Camellia sinensis (L.) O. Kuntze, for carbapenem-resistant Enterobacteriaceae (CRE) were compared to commonly used conventional antimicrobial agents. CRE was not only resistant to imipenem, meropenem or ertapenem, but also to various antimicrobial agents, such as amikacin (> $128{\mu}g/mL$). The hot water extracts of Camellia sinensis (L.) O. Kuntze had the lowest MIC ($0.06{\sim}0.5{\mu}L/mL$) of the carbapenem-resistant E. coli, K. pneumoniae, and Enterobacter spp. tested, and it was possible more potent than various conventional antimicrobial agents. Synergistic combinations of the extract with used commonly antimicrobial agents might even improve its antimicrobial chemotherapy property.

The Antimicrobial Food Packaging: Application of Antimicrobial Agents in Food Packaging (항균 식품포장: 식품 포장에서의 항균물질의 응용)

  • Cha, Dong-Su;Kweon, Dong-Keon;Park, Hyun-Jin
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.11 no.2
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    • pp.101-107
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    • 2005
  • The term 'antimicrobial' packaging encompasses any packaging technique(s) used to control microbial growth in the food product. These include packaging materials and edible films and coatings that contain antimicrobial agents, and also techniques that modify the atmosphere within the package. In recent years, antimicrobial packaging has attracted much attention from the food industry because of the increase in consumer demand for minimally processed, preservative-free products. Reflecting this demand, the preservative agents must be applied to packaging in such a way that only low levels of preservatives come into contact with the food. The film or coating technique is considered to be more effective, although more complicated to apply. New antimicrobial packaging materials are being developed continually. Many of them exploit natural agents, to control common food-borne microorganisms. Current trends suggest that in due course, packaging will generally incorporate antimicrobial agents and the sealing systems will continue to improve. The focus of packaging in the past has been on the appearance, size and integrity of the package. A greater emphasis on safety features associated with the addition of antimicrobial agents is perhaps the next area for development in packaging technology.

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Development of Antimicrobial Concrete for Sewage Structures and Application to Construction Field (하수구조물용 항균콘크리트의 개발 및 현장적용)

  • Kim Moo-Han;Kim Gyu-Yong;Lee Eui-Bae;Lee Seung-Hoon;Sohn Yu-Shin
    • Journal of the Korea Institute of Building Construction
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    • v.6 no.3
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    • pp.91-97
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    • 2006
  • Sewage facilities are positively necessary for environment improvement such as rainwater removal, sewage disposal, preservation of the qualify of water and health of the citizens in present-day. Meanwhile, a deterioration of the concrete sewer pipe is increasing rapidly due to the chemical and physical attack and especially biochemical attack that is to say biodeterioration. In this study, researches for the development of antibiotics and antimicrobial concrete were conducted to reduce biochemical corrosion of sewage concrete. First of all, desired performance, such as watertightness, antibiosis, homogeneity, workability and harmlessness, was proposed and performance of antibiotics and antimicrobial concrete were evaluated by them. And developed antimicrobial concrete was applied to actual construction field. As results of this study, dispersibility and antibiosis of liquid antibiotics superior to powdery antibiotics. Antibiosis of antimicrobial concrete was verified, and amount of elution of harmful and effective ingredients was little. In workability, setting time of antimicrobial concrete was delayed. Compressive strength and resistance to carbonation of antimicrobial concrete were more increased than ordinary concrete. Finally, as there were no problems in quality and construction progress of antimicrobial concrete produced in plant, applicability of antimicrobial concrete to actual construction field was verified.

Antimicrobial Activity of Antimicrobial Peptide LPcin-YK3 Derived from Bovine Lactophoricin

  • Kim, Ji-Sun;Jeong, Ji-Ho;Cho, Jang-Hee;Lee, Dong-Hee;Kim, Yongae
    • Journal of Microbiology and Biotechnology
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    • v.28 no.8
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    • pp.1299-1309
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    • 2018
  • We previously reported on lactophoricin (LPcin), a cationic ${\alpha}-helical$ antimicrobial peptide derived from bovine milk, which has antimicrobial effects on Candida albicans as well as Gram-positive and Gram-negative bacteria. In this study, we designed the LPcin-YK3 peptide, a shorter analog of LPcin, and investigated its antimicrobial activity. This peptide, consisting of 15 amino acids with + 3 net charges, was an effective antimicrobial agent against the on the Gram-positive strain, Staphylococcus aureus (MIC: $0.62{\mu}g/ml$). In addition, the hemolytic activity assay revealed that the peptide was not toxic to mouse and human erythrocytes up to $40{\mu}g/ml$. We also used circular dichroism spectroscopy to confirm that peptide in the presence of lipid has ${\alpha}-helical$ structures and later provide an overview of the relationship between each structure and antimicrobial activity. This peptide is a member of a new class of antimicrobial agents that could potentially overcome the problem of bacterial resistance caused by overuse of conventional antibiotics. Therefore, it could be used as a therapeutic or natural additive, particularly in the cosmetics industry.