• Clinical and Experimental Pediatrics
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• v.52 no.8
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• pp.856-861
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• 2009

Cardiopulmonary arrest has long been accepted as an unquestionable definition of death. An advent of cardiopulmonary resuscitation and artificial ventilation along with the development of organ transplantation has prompted the emergence of the concept of brain death. The criteria for brain death are based mainly on the clinical examination of coma, apnea and total loss of brain stem function. Although organ transplantation by donor brain death has increased in Korea over recent years, there is still a substantial shortage of donor organs compared to the demand. Improvement of government policies and changes of social culture for organ donation are needed for the activation of organ transplantation by donor brain death. Pediatricians have an important role for the search of potential donors in cases of brain death and optimal medical care for successful organ transplantation.

• Proceedings of the Korean Society of Computer Information Conference
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• 2021.07a
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• pp.343-345
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• 2021

본 논문에서는 4D 프린팅을 이용한 인공장기이식에 대해 소개한다. 여러 외부적 요인에 대처할 수 없었던 3D 바이오 프린팅의 단점을 보완하여 자가변환 및 자가조립이 가능한 재료를 3D프린터로 찍어낸 다음, 그 물체가 주변환경에 의해 스스로 모양이 변화하는 기술인 4D 프린팅을 이용한다. 또한, 4D 프린팅은 변형이 가능한 특수 소재를 사용함으로써 시간이 지나면 출력한 결과물의 모양이 변하게 되고, 시간 및 온도·습도·압력 등의 외부적인 요인에 스스로 능동적으로 대처할 수 있다. 본 논문에서는 4D 프린팅 기술로 제작한 작은 인공장기를 인체에 삽입함으로써 수술 후 감염 및 합병증 등의 부작용을 최소화할 수 있고 수술 시간을 크게 단축할 수 있다는 면에서 우수함을 보인다.

• Journal of Convergence for Information Technology
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• v.9 no.10
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• pp.227-233
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• 2019

This study surveyed the dental hygiene and health science students in order to grasp the bioethics consciousness from June to July 2018 and to provide basic data for the development of the bioethics curriculum. Correlation between fetal right of life and artificial insemination awareness was significant in gender(r=0.241), religion(r=-0.176), and department(r=-0.160). Correlation between awareness of organ donation and organ transplantation was significant in grade(r=0.129), religion(r=-0.098), bio ethics educ ation(r=0.235). Correlation of euthanasia perception was significant in religion (r=0. 139), bioethics education(r=-0.157). As a result, To establish an ethical view that is desirable for health college students, Necessary to develop a curriculum and to sys tematically run education programs by analyzing the factors that affect biomedical ethics.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.137-147
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• 2018

This study is a descriptive evaluation of the differences in biomedical ethics consciousness, related knowledge, awareness, and attitude of nursing college students according to the completion of biomedical ethics education. The data were collected from 112 nursing students using self-report questionnaires and analyzed by t-test, Chi-Square test, Fisher's exact probability test and Pearson's correlation coefficient using SPSS 21.0. There were significant differences between the two groups in the sub-domains of biomedical ethics consciousness, artificial insemination, euthanasia and organ transplantation. The biomedical ethics consciousness was positively correlated with attitudes toward human tissue donation and transplantation, awareness of death, and awareness of hospice palliative care. The results of this study showed that after participating in the biomedical ethics education, nursing college students had statistically significant differences in the consciousness of artificial insemination, euthanasia, and organ transplantation. Moreover, the consciousness of biomedical ethics was related to attitude toward human tissue donation and transplantation and awareness of hospice palliative care. Based on the results of this study, we would like to suggest the need for development of various curricula related to death, hospice palliative care, human tissue donation and transplantation in the biomedical ethics curriculum. In addition, as the study was conducted in a single college, it is difficult to generalize the results; therefore, additional studies at different facilities are recommended.

• KSBB Journal
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• v.30 no.6
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• pp.268-274
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• 2015

3D printing technology has been used in various fields such as materials science, manufacturing, education, and medical field. A number of research are underway to improve the 3D printing technology. Recently, the use of 3D printing technology for fabricating an artificial tissue, organ and bone through the laminating of cell and biocompatible material has been introduced and this could make the conformity with the desired shape or pattern for producing human entire organs for transplantation. This special printing technique is known as "3D Bio-Printing", which has potential in biomedical application including patient-customized organ out-put. In this paper, we describe the current 3D bio-printing technology, and bio-materials used in it and present it's practical applications.

• International Journal of Fluid Machinery and Systems
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• v.3 no.2
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• pp.102-112
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• 2010

Artificial heart pumps have attracted the attention of researchers around the world as an alternative to the organ used in cardiac transplantation. Conventional centrifugal pumps are no longer considered suitable for long-term application because of the possibility of occurrence of blood leakage and thrombus formation around the shaft seal. To overcome this problem posed by the shaft seal in conventional centrifugal pumps, the magnetically suspended centrifugal pump has been developed; this is a sealless rotor pump, which can provide contact-free rotation of the impeller without leading to material wear. In Europe, clinical trials of this pump have been successfully performed, and these pumps are commercially available. One of the aims of our study is to numerically examine the internal flow and the effect of leakage flow through the gap between the impeller and the pump casing on the performance of the pump. The results show that the pressure head increases compared with the pump without a gap for all flow rates because of the leakage of the fluid through the gap. It was observed that the leakage flow rate in the pump is sufficiently large; further, no stagnant fluid or dead flow regions were observed in the pump. Therefore, the present pump can efficiently enhance the washout effect.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.18 no.3
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• pp.401-410
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• 2011

Purpose: The purpose of this study was to provide basic data necessary for educating nursing students by establishing a desirable sense of ethics values. Method: In this descriptive research, 101 nursing students and 191 non-nursing students (in other health related fields) from Daejeon City were selected. Tools used for data analysis were descriptive statistics, t-test, one-way ANOVA, Scheffe test and step wise multiple regression with SPSS/WIN 12.0 version. Results: Average scores for consciousness of biomedical ethics in nursing students was 2.94, and in non-nursing students, 2.77. When differences in the consciousness of biomedical ethics of nursing and non-nursing students were compared, nursing students had significantly higher scores for artificial abortion, artificial insemination, prenatal diagnosis of fetus, right to life of newborn, euthanasia, organ transplantation and human biotechnology, but significantly lower for brain death. Variables which influenced consciousness of biomedical ethics were religion and economic status in the nursing students and intent to attend a class in biomedical ethics, quantity and quality of biomedical ethics in the current curriculum and religion in the non-nursing students. Conclusion: Continuing educational programs need to be considered and attention given to the significant variables that can promote consciousness of biomedical ethics in nursing students.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.30 no.5
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• pp.438-443
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• 2004

Objectives : The proper development of the facial structures relies upon a sequence of tightly regulated signaling interactions between the ectoderm and mesoderm involving the participation of several families of signaling molecules. Among these, bone morphogenetic proteins (BMPs) have been suggested to be a key signal that regulates the development of the mandible and the initiation and morphogenesis of the teeth. The aim of this study was to examine the artificial development of the mandibular structures and to examine the role of BMPs on tooth morphogenesis and differentiation using an organ culture system. Materials and Methods : The tooth germs from Ed 11.5, 13.5 mice were dissected, and transplanted into the diastema of the mandible primordia. The mandibles containing the transplanted tooth germs were cultured in vitro. During this period, beads soaked with BMP4 were implanted around the transplanted tooth germs. In addition, a diastema block containing the transplanted tooth germ was dissected, then transferred to an adult mouse kidney. After the organ culture, the developing mandibular explant was removed from the kidney and prepared for the tissue specimens. Odontogeneis of the transplanted tooth germs was examined after Hematoxylin-eosin, Masson-trichrome staining. Results : Proliferation and differentiation of the tooth germs cultured in the diastema was observed. In the BMP4-treated tooth germs, the formation of the first and second molars was noted. The crown of the developing tooth showed the formation of a mature cusp with the deposition of enamel and dentin matrix. In conclusion, it was confirmed that BMP4 is involved in the formation of a dental crown and the differentiation of ameloblasts and odontoblasts of the molar tooth during the development of the transplanted tooth germs.

• Journal of Industrial Convergence
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• v.19 no.4
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• pp.49-55
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• 2021

This study attempted to review the research on biomedical ethics of nursing students published in Korea. Keywords included 'nursing students', and 'biomedical ethics', and a total of 26 studies were collected via databases such as KISS, NDSL, RISS. The biomedical ethics awareness was the main concept of biomedical ethics, consisted of right to life of fetus, artificial insemination, organ transplantation, and so on. There were differences in biomedical ethics awareness by ethical education experience, grade, clinical practice experience, and ethical education willingness to attend. Also, major keywords analysed with biomedical ethics were withdrawal of life-sustaining treatment, critical thinking, sexual attitude, nursing professionalism, and death perception. Study results can be used to provide basic data for preparing nursing ethics education in the future.

• Journal of Biomedical Engineering Research
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• v.25 no.1
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• pp.1-4
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• 2004

On the background of general idea and technique of bioscience, medicine and engineering, tissue engineering aim at maintenance, improvement and repair of human body function through manufacturing and transplantation of artificial tissue and organ exchangeable human body. Basic material used in the area is scaffold that aid tissue and organ formation. Making scaffold, solvent-casting and particulate leaching technique is widely used in manufacturing of porous polymer scaffold. There are many types of particle including salt and gelatin. Salt is a most commonly used particulate because it is easily available and very easy to handle and gelatin particle is another candidate for this method because it is known as a material, which enhances cell attachment and proliferation. But there is no comparative study of two kinds of materials. In this study we compared the biocompatibility of the two scaffolds made from salt(salt scaffold) and gelatin particle (gelatin scaffold). These results demonstrated that gelatin scaffold showed better attachment of cells at the initial stage and better proliferation of cells. The better performance of gelatin scaffold is contributed to the better connection of pores in the same porosity.