• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.272.1-272.1
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• 2002

We have carried out collaborative study to evaluate a preparation of antithrombin concentrate whether or not it was suitable to serve as the candidate for a Korea National Biological Standard. Six laboratories. including three manufacturers and three National Control Laboratories. participated in this study. The potency of this candidate preparation was determined using the heparin cofactor chromogenic method. (omitted)

• Journal of Applied Biological Chemistry
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• 제50권3호
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• pp.136-143
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• 2007

Despite the increased interests in biological control of soilborne diesease for environmental protection, biological control of bacterial wilt caused by Ralstonia solanacearum have not provided consistent or satisfying results. To enhance the control efficacy and reducing the inconsistency and variability, combinations of specific strains of microorganisms, each having a specific mechanism of control, were applied in this study. More than 30 microorganisms able to reduce the activity of pathogen by specific mechanism of action were identified and tested for their disease suppressive effects. After in vitro compatibility examinations, 21 individual strains and 15 combinations were tested in the greenhouse. Results indicated three-way combinations of different mode of control, TS3-7+A253-16+SKU78 and TS1-5+A100-1+SKU78, enhanced disease suppression by 70%, as compared to 30-50% reduction for their individual treatments. This work suggests that combining multiple traits antagonizing the pathogen improve efficacy of the biocontrol agents against Ralstonia solanacearum.

• The Plant Pathology Journal
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• 제22권3호
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• pp.289-294
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• 2006

Two isolates of mucous bacteria, mc75 and pc78, were isolated from fungal culture plate as culture contaminants with an interesting swarming motility. Both isolates were identified as Pseudomonas fluorescens based on microscopy, biochemical analysis, Biolog test and DNA sequence analysis of the 16S rRNA gene. Both strains have the exactly the same 16S rRNA gene sequences, and yet their biological control activity were not identical each other. In vitro analysis of antagonistic activity of two isolates against several plant pathogenic fungi indicated that both produced diffusible and volatile antifungal compounds of unknown identities. Treatment of the bacterial culture of P. fluorescens pc78 and its culture filtrate exhibited a strong biological control activity against rice sheath blight in vivo among six plant diseases tested. More effective disease control activity was obtained from treatment of bacterial culture than that of culture filtrate. Therefore, in addition to antifungal compound and siderophore production, other traits such as biofilm formation and swarming motility on plant surface may contribute to the biological control activity of P.fluorescens pc78 and mc75.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2005년도 한국식물병리학회 임시총회 및 춘계학술발표회
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• pp.74.1-74.1
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• 2005

• 환경생물
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• 제39권1호
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• pp.39-45
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• 2021

환경친화적 생물적방제를 위해 수출딸기온실에서 해충인 점박이응애 밀도 감소 효율을 화학적방제와 생물적방제로 나누어 동일한 크기의 동일한 온실에서 각각 비교하였다. 생물적방제 온실은 점박이응애의 천적인 칠레이리응애만을 이용하였고, 화학적방제 온실은 일반 화학합성 농약을 이용하여 점박이응애의 밀도를 조절하였다. 화학적방제 온실에 비해 생물적방제 온실에서 점박이응애 모든 태의 밀도가 낮게 관찰되었으며, 생물적방제를 위한 비용이 화학적방제에 비해 낮았다. 이러한 결과는 수출딸기의 주요해충인 점박이응애의 방제에 칠레이리응애를 이용한 생물적방제가 가능한 것을 나타내고 있다.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 1994년도 Proceedings of International Symposium on BIOLOGICAL CONTROL OF PLANT DISEASES Korean Society of Plant Pathology
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• pp.1-10
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• 1994

Biological control of plant disease has been considered a potential control strategy in integrated pest management in recent years. This paper reviewed the progress of research on the biological control of plant diseases in Korea during the last two decades and adopts some future prospects. The crop diseases included, red pepper, Phytophthora blight, ginseng root rots cucumber wilt, sesame damping-off, strawberry wilt and tobacco bacterial wilt and mosaic. Biological control of plant diseases requires a multi-disciplinary approach involving input from plant pathologists, ecologists, mycologists and molecular biologists. The author proposed to organize a group“Committee for Biological Control”including researchers, industries, growers and administrators.

• 한국잡초학회지
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• 제31권1호
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• pp.8-23
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• 2011

유기농 재배에서 이용되고 있는 잡초방제 기술 및 연구 동향을 검토하고 앞으로 방향을 제시하기 위하여 화학적 방제를 배제하고 기계적 방제, 경종적 방제, 생물적 방제를 포함한 종합방제 기술에 대한 문헌을 정리하고 분석하여 유기농업에서의 새로운 잡초 관리방안을 전망하고자 하였다. 물리적 방법은 기계적 방법, 열, 광선, 전기충격, 압축공기, 로봇잡초방제기술, 그리고 경종적 방법은 멀칭, 경운, 윤작, 피복식물, 경합을 이용한 방법이 포함된다. 생물적 방제는 미생물제초제, 대량증식 생물제제, 광역 생물제제, 상호대립억제물질 등이 개발되거나 또는 이용되고 있다. 유기농재배에서 성공적인 잡초방제를 위하여 물리적 방법과 경종적 방법은 제초제 사용이 제한된 조건에서 가장 중요한 잡초방제 수단이므로 기계적, 경종적 방법을 근간으로 하고 생물적 방법이 조화롭게 보완되는 종합잡초관리방법이 요구된다. 그리고 유기농 재배에서 수익을 창출하고 적합한 장기적 잡초관리 방안을 도출하기 위하여 잡초관리 결정에 도움이 되는 모델의 개발도 필요하다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.2457-2460
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• 2003

There is a great demand to manipulate biological cell autonomously since biologist should spend much time to obtain skillful manipulation techniques. For this purpose, we propose a cell chip to control, carry, fix and locate the cell. In this paper, we focus on the cell rotator to rotate individual biological cell based on a micro fluidics technology. The cell rotator consists of injection hole and rotation well to rotate a biological cell properly. Under the variation of flow rate in injection hole, the angular velocity of a biological cell is evaluated to find the feasibility of the proposed rotation method. As a practical experiment, Zebrafish egg is employed. Based on this research, we find the possibility of non-contact rotation way that can highly reduce the damage of the biological cell during manipulation. To realize an autonomous biological cell manipulation, a cell chip with manipulation well and micro channel in this research will be utilized effectively in near future.

• Journal of Microbiology and Biotechnology
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• 제15권4호
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• pp.701-709
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• 2005

An efficient method of selecting an antagonistic strain for use as a biological control agent strain was developed. In this improved method, the surface tension reduction potential of an isolate was included in the 'decision factor,' in addition to two other factors; the growth rate and pathogen inhibition. By using a statistically designed method, an isolate from the soil was selected and identified as Bacillus sp. GB 16. In the pot test, this strain showed the best performance among the isolated strains. The lowest disease incidence rate and fastest seed growth were observed when the Bacillus sp. GB 16 was used. The action of the surface tension reducing component was assumed to enhance the wetting, spreading, and residing of the antagonistic strain in the rhizosphere. This result showed that the improved selection method was quite effective in selecting the best antagonistic strain for the biological control of soilborne infectious plant pathogens.

• 수면정신생리
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• 제5권1호
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• pp.34-44
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• 1998

Living organisms are influenced by many external rhythms and they have adapted their physiology to periodically changing conditions. These adaptive strategies are controlled by endogenous innate programs of behavior and physiology which are determined by external signals ("Zeitgeber"). There are many biological rhythms, each with its own characteristic functional adaptation. Among them, the presence of endogenous time control of feeding and drinking becomes obvious. There are increasing evidences that the control of food intake, food selection, and drinking are regulated by the endogenous rhythms including a circadian rhythm. However, there have been many restrictions in understanding the endogenous control of food intake itself and its mechanism. To broaden our know ledges of the endogenous time control of feeding and drinking, the author reviwed the characteristics of the endogenous timing for food intake, the influence of circadian pacemakers and food-entrainable oscillators, the interaction between the circadian control and the external and internal conditions in the control of food intake, the conseqences of feeding, the circadian control of food selection, and the biological cycles in energy balance.