• Title/Summary/Keyword: biopotency

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Assessment of allergenicity of genetically modified foods (GMOs)

  • Lee, Jung-Hyun;Yoon, Won-Ki;Han, Sang-Bae;Yun, Si-On;Park, Sun-Hong;Lee, Hyun-Ju;Yoon, Pyung-Seop;Moon, Jae-Sun;Kim, Hyung-Chin;Kim, Hwan-Mook
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.267.1-267.1
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    • 2002

  • The potential allergenicity of the transgene products in genetically modified organisms (GMOs). has been an important issue. As a part of the risk assessment of GMOs. we investigated the physicochemical stability and the immunogenicity of food allergens to determine their allergenicity. We have systematically evaluated the stability of food allergens in the gastrointestinal tract by using simple models of gastric (Stimulated gastric fluid) and intestinal (Stimulated intestinal fluid) digestion. (omitted)

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ASSESSMENT OF STABILITY AND ALLERGENICITY OF FOOD ALLERGENIC PROTEINS

  • Lee, J-H;Yoon, W-K;Han, S-B;Yun, S-O;Park, S-H;Lee, H-J;Yoon, P-S;Moon, J-S;Kim, H-C
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.180-180
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    • 2002

  • The potential allergenicity of the transgene products in genetically modified organisms (GMOs), has been an important issue. As a part of the risk assessment of GMOs, we investigated the physicochemical stability and the immunogenicity of food allergens to determine their allergenicity.(omitted)

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Activation of toll-like receptor signaling by polysaccharide isolated from cell culture of Acantopanax senticosus

  • Ahn, H-J;Han, S-B;Yoon, Y-D;Lee, H-S;Moon, J-S;Lee, C-W;Lee, K-H;Park, S-K;Kim, H-C
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.182-182
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    • 2002

  • We investigated the mechanism of immunomodulatory action of polysaccharide isolated from cell culture of Acanthopanax senticosus (ASP). ASP was found to increase directly proliferation and differentiation of B cells, and cytokine production of macrophages, but not proliferation and cytokine production of T cells.(omitted)

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Allergina inhibits the progression of graft rejection, hypersensitivity, and collagen-induced autoimmune arthritis

  • Lee, C-W;Han, S-B;Yoon, P-S;Jeong, C-M;Lee, M-L;Kim, K-M;Yoon, Y-D;Kim, H-C;Park, S-K
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.181-181
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    • 2002

  • The herbal combination allergina has been used for the treatment of inflammatory diseases in South Korea. In this study, we investigated the immunosuppressive activities of allergina in more detail. Acute graft-versus-host disease (GVHD) is a major cause of morbidity and mortality in patients undergoing allogeneic bone marrow transplantation.(omitted)

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The use of culture systems for the study of oligodendrocyte development and injury: The erbB2 gene is required for the development of terminally differentiated spinal cord oligodendrocytes

  • Park, Song-Kyu;Kim, Hwan-Mook;Timothy Vartanian
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.05a
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    • pp.14-23
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    • 2002

  • The nervous system consists of two types of cells, which are neurons and glial cells. Among the glial cells, oligodendrodendrocytes and schwann cells form myelin sheaths in the central nervous system (CNS) and the peripheral nervous system (PNS), respectively. The major function of myelin in vertebrates is to insulate axonal and help action potential travel faster.(omitted)

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