• Research in Community and Public Health Nursing
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• v.8 no.1
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• pp.21-30
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• 1997

The purpose of the study is to establish the nurses engaged in blood donation business right cognition and supply base data to make out proper directed blood donation rule through investigation of actual condition and general issue related to directed blood donation. In this study I searched for related reference and computed the directed blood donors in seoul national university hospital blood bank. The directed blood donation in Korea have been increased for supplying fresh whole blood and plateletpheresis donor blood. The most blood donation in the blood bank belong to hospital are directed blood donation. The benefits of directed blood donation are enlargement blood donor, easy insurance a demand type of blood. But that program also give rise to recipient severe burden, additional cost and confused blood donation system. First of all for lessening the burden of the recipient and the directed blood donor, blood donation site, time, cost and procedure must be repared by proper rules. An alternative plans for the directed blood donation are autologous blood program and donor registration system.

• Herbal Formula Science
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• v.12 no.2
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• pp.47-55
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• 2004

Wang Cheong-Im(1768-1831) in the Ching dynasty conducted the therapy of blood statis syndrome using the methods for promoting blood circulation and removing blood statis in accordance with the description in the book Uirimgaechak(醫林改錯). Thus, this study examined his methods for promoting blood circulation and removing blood statis, therapy of blood statis syndrome and mechanism of function. Since the blood statis symptoms varied on the parts where the blood statis were occurred, the therapy for promoting blood circulation and removing blood statis applied different treatments and drugs depending on the symptoms. The therapy also valued much of qi and blood. Qi is important to the human body so that the therapy replenished qi and simultaneously promoted the blood circulation as mainly focusing on the regulation of the qi flow. Moreover, the therapy adjusted the level of removing blood circulation and rate of replenishing qi. The degree of prescription and drug was differentiated in treating a variety of blood statis because of the difference in the seriousness and characteristics of blood circulation, amount and application of drug and combination of drugs. The therapy was careful about the regulation of qi for the replenishment of qi and the nurishment of blood for the promotion of blood circulation. If the blood circulation was blocked, the blood statis was formed. Accordingly, the phlegm and the blood statis were closely related. Then, the phlegm and blood statis were simultaneously treated. The therapy divided the properties of blood statis into the stagnant excess syndrome, the stagnant deficiency syndrome, the stagnant cold syndrome and the stagnant heat syndrome and treated the patients suitable for each symptom. The function of mechanism in the treatment using the methods for promoting blood circulation and removing blood statis was divided into the stagnation of blood and interruption in blood circulation. The therapy laid stress on promoting blood circulation and removing blood circulation. With such emphasis, the therapy facilitated the circulation in the bloood vessel, prevented the coagulation of blood, removed the blood statis and promoted the metabolism. Then, the physiological function and pathological change internal organs were improved. Furthermore, the therapy strengtened the heart and promoted the blood circulation by improving the systemic blood circulation. Moreover, the therapy facilitated the micro-circulation by adjusting the balance of body.

• Journal of Korean Medical classics
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• v.29 no.2
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• pp.165-176
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• 2016

Objectives : This study was done to investigate the formation process of the 'The Spleen controls the blood(脾統血)' concept, to clarify what this concept means and the mechanism of its physiology. Methods : Contents including 'Controlling blood(統血)' and 'Binding blood(攝血)' were searched and analyzed in medical classics. Previous researches were applied. Results & Conclusions : The concept of 'Controlling blood' could be defined as the control of blood movement. This means that it sends blood to where it's needed, and inhibits flow from where it's excessive. 'The Spleen controls the blood' was not used as a physiologic term in early books like Huangdineijing(黃帝內經). It was first used in the 13C, then widely after the 16C. The mechanism of 'Controlling blood' could be classified as the function of 'Production', 'Distribution', and 'Adjustment' of blood. 'Production' of blood can reduce blood fever(血熱) and blood stasis(瘀血), and prevent bleeding. 'Distribution' of blood can reduce the symptoms raised by lack of blood in the five viscera and body. 'Adjustment' of blood means maintaining homeostasis and stability of the human body. Pi can adjust blood flow and prevent blood from being imbalanced.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.272.2-273
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• 2002

The safety of blood and blood products is ensured by careful selection of donors. screening of donated blood and the use of validated viral inactivation and/or removal steps during the manufacture of blood products. Serologic screening procedures have substantially reduces the risk of transmission of blood-bone viruses. However, there are still residual risks despite these measures due to the inclusion of 'window period'donations. (omitted)

• Journal of Environmental Science International
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• v.6 no.1
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• pp.69-73
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• 1997

Endotoxin from the cell wall of marine V. vujnificus was .extracted using the hot phenol-water method, injected endotoxin into rat, and tested the toxic effect of endotoxin on the blood component In rat blood. The results showed that blood glucose, blood urea nitrogen, white blood cell, and reticulocyte were Increased and red blood cell was the same as the number of control group(normal blood), but platelet was decreased. Above results suggested that endotoxin induced a malfunction of liver and that the Increase of white blood cell was for the removal of foreign toxic substance.

• 순환기질환의공학회:학술대회논문집
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• 2002.11a
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• pp.3-18
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• 2002

Hemorheology plays an important role in atherosclerosis. Hemorheologic properties of blood include whole blood viscosity, plasma viscosity, hemaocrit, RBC deformability and aggregation, and fibrinogen concentration in plasma. Blood flow is determine by three parameters (pressure, lumen diameter, and whole blood viscosity), whole blood viscosity is one of the key physiological variables. However, the significance of whole blood viscosity has not yet not been fully appreciated. Whole blood viscosity has a unique property, non-Newtonian shear-thinning characteristics, which is primarily due to the presence of RBCs. Hence, RBC deformability and aggregation directly affect the magnitude of blood viscosity, and any factors or diseases affecting RBC characteristics influence blood viscosity. Therefore, on can see that whole blood viscosity is the causal mechanism by which traditional risk factors such as hypertension, hyperlipidemia, smoking, exercise, obesity, age, and gender are related to atherogenesis. In this regard, we included whole blood viscosity in the three key determinants of injurious pulsatile flow that results in mechanical injury and protective adaptation in the arterial system. Because whole blood viscosity is a potential predictor of cardiovascular diseases, it should be measured in routine cardiovascular profiles. Incorporating whole blood viscosity measurements into a standard clinical protocol could improve our ability to identify patients at risk for cardiovascular disease and its complications.

• IMMUNE NETWORK
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• v.3 no.2
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• pp.83-88
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• 2003

The number of umbilical cord blood transplantation is increasing worldwide as it has expanded the ability of the transplantaion community to meet the growing needs of their patients. Clinical data over the last decade show promising results in transplantation using both related as well as unrelated cord bloods. Cord blood banks are essential for the clinical use for transplantation and are now established around the world with the major efforts to standardize banking in collection, processing and distribution of cord blood for providing the highest quality stem cells for the patients. In Korea, Medipost, Histostem and some regional cord blood banks were established some years ago and collected thousands of cord blood for public but it had some limitations and was not expanded as the cord blood transplantation was not covered by medical insurance. Recently with the change in the policy of medical insurance to cover the cord blood transplantation, several venture companies are showing great interests in cord blood banking and trying to establish private cord blood banks in Korea. This review article discusses the current status of cord blood transplantaion and also the clincial use of stem cells from cord blood.

• Proceedings of the KSME Conference
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• 2008.11a
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• pp.1487-1491
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• 2008

Detailed knowledge on the motion of blood cells flowing in micro-channels under simple shear flow and the influence of blood flow is essential to provide a better understanding on the blood rheological properties and blood cell aggregation. The microscopic behavior of red blood cell (RBCs) is numerically investigated using a fluid-structure interaction (FSI) method based on the Arbitrary-Lagrangian-Eulerian (ALE) approach and the dynamic mesh method (smoothing and remeshing) in FLUENT (ANSYS Inc., USA). The employed FSI method could be applied to the motions and deformations of a single blood cell and multiple blood cells, and the primary thrombogenesis caused by platelet aggregation. It is expected that, combined with a sophisticated large-scale computational technique, the simulation method will be useful for understanding the overall properties of blood flow from blood cellular level (microscopic) to the resulting rheological properties of blood as a mass (macroscopic).

• The Journal of Korean Medicine
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• v.24 no.2
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• pp.12-18
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• 2003

Objectives : Hypertension is very prevalent disease, and causes serious cardiovascular complications. Nowadays optimal hypertension treatment is emphasized to reduce the incidence of cardiovascular complications. Auricular acupuncture therapy is economical, safe and effective. Its clinical application is various, and it can be used to control blood pressure. So The effect of auricular acupuncture therapy was investigated. Daily variation of blood pressure during needle-embedded period and variation of blood pressure by blood pressure classification were observed. Methods : The auricular acupuncture points we used were Gangapjeom (降壓點), Sinmun (神門), Gyogam (交感), Sim(心), and Icheom (耳尖). Auricular acupuncture needles were embedded for three days. Blood pressure was checked four times per day and the mean obtained. Results : The following results were obtained : 1. During needle-embedded period, systolic and diastolic blood pressure decreased. Blood pressure decreased most significantly 2 days after treatment. 2. The change of blood pressure in the higher blood pressure group was more remarkable than that of the lower blood pressure group. Conclusions : Through this research, auricular acupuncture therapy is considered as an effective and safe method to lower blood pressure.

• Journal of Veterinary Clinics
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• v.14 no.2
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• pp.254-257
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• 1997

The blood components of not-young (young antler) were examined in the Red Deer. Blood samples were collected from the antler and jugular veins respectively. The hematological and serum chemical values were as follows; 1. RBC count of not-hyul (young antler blood) was significantly higher than that of jugular vein blood (p<0.05). However, fibrinogen concentration of rook hyul was significantly lower than that of jugular vein blood (p<0.01). WBC counts packed cell volume (PCV) and total protein fro) were not significant between nolo-hyul and jugular vein blood. 2. The concentration of phosphorous and magnesium of not-hyul were significantly higher than those of jugular vein blood (p<0.05). Albumin and glutamic oxaloacetic transaminase (GOT) of nolo-hyul were higher than those of jugular vein blood. But globulin and calcium concentration of not-hyul were lower than those of jugular vein blood. Blood urea nitrogen BUN) of rook-hyul was not significant when compared with that of jugular vein blood.