• Nutrition Research and Practice
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• v.13 no.3
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• pp.214-221
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• 2019

BACKGROUNDS/OBJECTIVES: Cancer treatment may lead to significant body composition changes and affect growth and disease outcomes in pediatric cancer patients. This prospective study aimed to evaluate short- and long-term body compositions changes focused on body fat during the first year of cancer treatment in children. SUBJECTS/METHODS: A prospective study was conducted in 30 pediatric cancer patients (19 hematologic malignancies and 11 solid tumors) and 30 age- and sex-matched healthy controls. Anthropometric measurements and body composition analysis using whole body dual energy X-ray absorptiometry were performed at baseline and 1, 6, and 12 month(s) of cancer treatment. Kruskal-Wallis tests, Wilcoxon paired t tests, and generalized estimation equation (GEE) were applied for statistical analysis. RESULTS: At baseline, no differences in weight, height, body mass index, abdominal circumferences, body fat, and fat-free mass were observed between 30 controls and 30 pediatric cancer patients. Total fat mass (P < 0.001) and body fat percentage (P = 0.002) increased significantly during the first month, but no changes were observed from 1 to 12 months; however, no changes in the total mass were observed during the first year of cancer treatment. Meanwhile, the total fat-free mass decreased during the first month (P = 0.008) and recovered between 6 and 12 months of follow-up (P < 0.001). According to GEE analysis, there was a significant upward trend in body fat percentage during the first year, especially the first month, of cancer treatment in children with hematologic malignancies, but not in those with solid tumors. CONCLUSIONS: Our results indicate that cancer treatment is related to significant body composition changes and rapid body fat gain, particularly during the first month after initiating cancer treatment, in children with hematologic malignancies. Therefore, individualized dietary strategies to prevent excessive fat gain are needed in pediatric cancer patients for better outcomes.

• The Journal of the Convergence on Culture Technology
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• v.5 no.4
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• pp.413-420
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• 2019

The purpose of the present study is to develop a model for predicting hypercholesterolemia using an integrated set of body fat mass variables based on machine learning techniques, beyond the study of the association between body fat mass and hypercholesterolemia. For this study, a total of six models were created using two variable subset selection methods and machine learning algorithms based on the Korea National Health and Nutrition Examination Survey (KNHANES) data. Among the various body fat mass variables, we found that trunk fat mass was the best variable for predicting hypercholesterolemia. Furthermore, we obtained the area under the receiver operating characteristic curve value of 0.739 and the Matthews correlation coefficient value of 0.36 in the model using the correlation-based feature subset selection and naive Bayes algorithm. Our findings are expected to be used as important information in the field of disease prediction in large-scale screening and public health research.

• The Journal of Korean Medicine
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• v.24 no.1
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• pp.9-28
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• 2003

Objects : The aim of this study was evaluate the effect of the Saengsig taken along with Behavior Modification Therapy, Methods : We examined the body compositions of 20 obese patients who were treated with Saengsig and Behavior Modification Therapy for 2 months by Inbody 2.0. Results : Changes of body composition due to Saengsig with Behavior Modification Therapy were reduction of body weight by $3.14{\pm}1.33{\;}kg$, lean body mass by $0.14{\pm}1.48{\;}kg$, fat mass by $3.00{\pm}1.53kg$ and BMI by $1.30{\pm}0.54$ Conclusion : Fat mass and body fat rate were significantly reduced after treatment with Saengsig with Behavior Modification Therapy.

• Journal of Acupuncture Research
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• v.32 no.4
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• pp.213-226
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• 2015

Objectives : This study was aimed to show the effect of electroacupuncture combined with magnetic acupuncture on abdominal obesity without patient dieting, exercise or use of herbal medication. Methods : Women over 85 cm in waist circumference were treated with electroacupuncture combined with magnetic acupuncture. Acupuncture points were located at the abdomen ($CV_{12}$, $CV_6$, $ST_{25}$, $ST_{21}$, $SP_{15}$, $SP_{14}$), extremities ($LI_4$, $LI_{11}$, $ST_{36}$, $ST_{44}$) and were stimulated 30 minutes with 2.1~3 Gaus, 500 Hz, tolerable strength. The Interference wave forms were by Whata 153 (Medi Lab, Korea). Two or three treatment sessions per week (five or ten sessions in total) were done. Before treatment, and after the last treatment, we measured waist circumference, hip circumference, waist hip ratio, thickness of abdominal subcutaneous fat, body weight, body mass index, body fat ratio, visceral fat area, free fat mass, body fat mass and skeletal muscle mass. We also measured the subcutaneous temperature of the abdomen($CV_{12}$, $ST_{25}(Rt)$, $ST_{25}(Lt)$, $CV_6$) by using digital infrared thermal imaging(DITI). Results : In this study, significant reductions were shown in waist circumference, hip circumference, thickness of abdominal subcutaneous fat, body weight, body mass index, body fat ratio and body fat mass. There were no significant differences in waist hip ratio, free fat mass or skeletal muscle mass. There were also significant increases of the subcutaneous temperature on $CV_{12}$, $ST_{25}(Rt)$, $ST_{25}(Lt)$. Conclusions : From the above results, electroacupuncture combined with magnetic acupuncture might be an effective treatment for abdominal obesity.

• Journal of Korean Medicine for Obesity Research
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• v.16 no.2
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• pp.116-123
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• 2016

Objectives: The purpose of this study was to investigate the effects of modified fasting therapy on the changes of body compositions. Methods: We analyzed the medical records of 33 patients, who carried out modified fasting therapy at Dunsan Korean Medicine Hospital of Daejeon University from January 1st, 2011 to December 30th, 2015. They went through reducing food intakes period (7 days), fasting period (14 days) and refeeding period (14 days). Body compositions (weight, body mass index, skeletal muscle mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) were reviewed at each state. And then the data was analyzed. Results: The body composition values (weight, body mass index [BMI], skeletal muscle mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) decreased during the fasting therapy period, as a whole. The weight, BMI, percent body fat and visceral fat area decreased during the reducing food intakes period, the fasting period and the refeeding period. The skeletal muscle mass and basal metabolic rate significantly decreased during the reducing food intakes period and the fasting period, and insignificantly increased during the refeeding period. Conclusions: Results from this investigation showed that modified fasting therapy using fermented herbal medicine have positive effects on changes of body compositions.

• Journal of the Korea Fashion and Costume Design Association
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• v.15 no.4
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• pp.17-27
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• 2013

This study has the purpose to examine the effects of stone massage therapy on abdominal obesity reduction. 10 sessions for 5 weeks two times a week of stone massage therapy were offered to 43 adult females who were 40s through 70s with 27% or more of body fat and the results were analyzed. The body composition like body fat mass, fat free mass, weight and skeletal muscular mass etc and the degrees of obesity like body fat ratio abdominal fat ratio were measured and analyzed before and after stone massage therapy. The results are as follows: First, the subjects were obese body type and stone massage therapy produced positive effects with body fat mass, fat free mass, weight and BMI value slightly less than before the therapy. Second, as the average values of body fat ratio and waist hip ratio of subject were significantly different statistically before and after the therapy, stone massage therapy was found to be effective in reducing abdominal obesity. Third, as for the change of waist hip ratio, the therapy was found to be effective in reducing waist hip ratio that 40s decreased insignificantly after the therapy, and 50s and 60s significantly at p<0.05 level respectively from 0.92 to 0.90 and from 0.93 to 0.92. In conclusion, the results of this study indicated that stone massage therapy has positive effects on abdominal obesity reduction, and can contribute to healthy life and well-being culture.

• Journal of Nutrition and Health
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• v.34 no.8
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• pp.865-871
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• 2001

The adipose tissue hormone leptin has been proposed to be involved in the regulation of flood intake and energy expenditure via thermogenesis by uncoupling protein(UCP) in brown adipose tissue(BAT). The objective of the study was to examine the effects of high fat diet on the serum leptin levels, BAT UCPl expression and the body fat mass in rats after weaning. During experimental period of 12 weeks, 4 male Sprague-Dawley rats were killed for the baseline experiment at 4 weeks of age while the remaining rats were fed the two different diets: the control diet AIN-76A(n = 20), high fat(beef tallow) diet(n = 20) ad libitum, which provided 11.7% or 40% of calories as fat, respectively. At 16 weeks of age, the increase in the food efficiency ratio(FER) was related to fat mass in rats on high fat diet. Serum leptin level was increased by age and dietary high fat. There was no difference in serum insulin level between groups until 10 weeks of age, but rats fed high fat diet for 12 weeks showed hyperinsulinemia. The amount of body fat pads was increased significantly in high fat group compared to normal diet group. Visceral fat mass affected acutely by high fat diet, as a result, it was higher in rats fed high fat diet for 2 weeks than normal diet. At 16 weeks of age, BAT and visceral fat mass were significantly high in high fat group. Also, the serum leptin levels reflected the amount of body fat mass. BAT UCPI mRNA expression increased with age and dietary high fat. This study demonstrates that dietary high fat increased serum leptin levels, BAT UCPI expression and body fat mass. Futhermore, in rats fed high fat diets, the increases in leptin and UCPI expression counteracts only in part the excess adiposity and obesity.

• Journal of Korean Medicine for Obesity Research
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• v.17 no.2
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• pp.87-95
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• 2017

Objectives: This study was conducted to evaluate efficacy and safety of Punica granatum L. Actinidia chinensis Planch. mixed extract on body fat. Methods: Thirty women were recruited ($25kg/m^2{\leq}body$ mass index [BMI]${\leq}29.9kg/m^2$) ($19yr{\leq}age{\leq}38yr$) and randomized to receive Punica granatum L. Actinidia chinensis Planch. mixed extract or placebo for 8 weeks. During the test, they visited four times including screening. Body fat mass, body fat rate, anthropometric dimensions at waist and hip, waist-hip ratio, total cholesterol, triglyceride, low density lipoprotein-cholesterol (LDL-C), and high density lipoprotein-cholesterol (HDL-C) were measured at screening and 8 weeks after screening. Adverse reaction were also checked each visit. Results: There were no significant differences in all index. But when divide experimental group by BMI index, age, and compliance, less than BMI $27kg/m^2$ group decreased body weight, body fat mass and more than BMI $27kg/m^2$ group also decreased body weight, body fat mass and waist circumference. Less than age 30 years group showed decline of waist circumference, fat free rate and T-cholesterol and more than age 30 years group showed decline of fat free mass. Group with compliance more than 95% was decreased BMI, fat free mass, and hip circumference. Conclusions: There was no significant efficacy as compared with placebo group, but as divide experimental group according to BMI index, age, compliance, mixed extract might be effective to reduce obesity index.

• Journal of the Korean Dietetic Association
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• v.7 no.2
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• pp.153-158
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• 2001

This study examined the age-related patterns in body composition cross-sectionally using Segmental bioelectrical impedance analysis(SBIA), specifically its two components, lean body mass(LBM) and body fat mass, in 1,452 men and 1,436 women with an age range of 19 to over 70 years . Mean height of male subjects was 174.1cm at peak in early 20's and was decreased continuously 0.2-0.3 cm every year. Mean weight was greatest between late 20's and 40's, and was decreased quickly in 70's. Body fat mass was increased steadily before 30's and remained thereafter. Because decreasing lean body mass (LBM), percentage of body fat(PBF) increased continuously with aging. Mean height of female subjects was 161.7 cm at peak in 20's and was decreased steadily around 0.2 cm every year and thus an individual's height was decreased approximately 10 cm in their life cycle. Body weight was increased steadily until 50's and then was decreased. Body fat mass was increased continuously and LBM remained constant and thus PBF was increased steadily with aging. SBIA can be used to compare body composition between genders and between ages. In future studies, SBIA could be applied widely to evaluate variations of body composition in subjects with different nutritional problems.

• Nutritional Sciences
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• v.8 no.1
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• pp.50-55
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• 2005

This study was conducted to determine the relationship between the body fat percent (BF%) and body mass index (BMI) of Koreans and the differences with Caucasians. Complete data were collected from 3297 subjects (2441females and 856 males) between the ages of 18 and 79. Data were collected between September 2001 and November 2001 in Seoul and Pusan. For the statistical analysis, only the data on subjects between the ages of 18 and 65(3200) were used Body weight and height were measured BMI (kg/$m^2$) was computed From BMI, BF (%) was calculated using age- and sex-specific prediction formulas. BF% was assessed using an INBODY 2.0 body fat analyser. Data analysis showed that the females were significantly younger than the males, were smaller, lighter and had a lower body mass index. Body fat percent of the females was higher than that of the males. 1he differences between actual measured BF% and BF% as predicted from prediction equations from the literature, based on BMI, age and sex, were correlated with level of body fat and age. There is a significant age-related decrease in body fat in Koreans for any given BMI and sex, which is remarkably different compared to age-related increases in body fat in the European reference group. For the same age and BF%, Korean females have a slightly lower BMI than their European counterparts. Korean males have, for the same age and BF%, a higher BMI than their European counterparts. The differences between females and males were not significant. It was concluded that, assuming that the data on body fat percent was correct, that the relationship between BF% and BMI is quite different in Koreans than in European Caucasians. Thus, for younger Koreans cut-off values for obesity should be slightly lower than those for Caucasians whereas for older Koreans the cut-off points for obesity should be higher than those for Caucasians.