• Journal of Korean Academy of Nursing
• /
• v.45 no.5
• /
• pp.733-741
• /
• 2015

Purpose: This study was a descriptive survey research to identify the impact of bowel function, anxiety and depression on quality of life in patients with rectal cancer who had a sphincter-preserving resection. Methods: Participants were 100 patients who had rectal cancer surgery at W hospital in Korea. Bowel function, anxiety & depression, and quality of life were measured using the BFI (Bowel Function Instrument), HADS (Hospital Anxiety-Depression Scale) and the FACT-C (Functional Assessment of Cancer Therapy-Colorectal). Results: The mean scores were $39.81{\pm}5.16$ for bowel function, $6.15{\pm}3.25$ for anxiety, $7.24{\pm}3.13$ for depression, and $72.50{\pm}13.27$ for quality of life. There were significant negative correlations between quality of life and anxiety (r= -.59, p <.001) and between quality of life and depression (r= -.53, p <.001). But the correlation between quality of life and bowel function was significantly positive (r=.22, p =.025). The influence of the independent variables on the total quality of life was examined using multiple regression analysis. Anxiety (${\beta}$= -.38, p =.002), bowel function (${\beta}$= -.25, p =.028) and occupation (${\beta}$=.16, p =.048) were identified as factors affecting quality of life. The explanation power of this regression model was 44% and it was statistically significant (F=16.53, p <.001). Conclusion: The results of this study indicate that in order to improve the bowel function of patients after sphincter-preserving resection for rectal cancer, effective nursing interventions should be developed. As psychological problem such as anxiety and depression can relate to quality of life for these patients, nurses should work on improving the situation by providing continuous emotional nursing.

• Journal of Nutrition and Health
• /
• v.26 no.9
• /
• pp.1085-1097
• /
• 1993

Recently, as korean eating habits have been westernized, the incidence of large intestinal disease, which has been recognized as western diseases until now, has been increasing. This study was conducted to find the association of fiber intake and large bowel function. This was a cross-sectional survey, the data were obtained by self-administering questionnaire and study population was adults aged more than 18 years old in Seoul(N=1200). The response rate was 81.8%. The results were summarized as followed: 1) The factors associated with bowel function was sex, habits of defecation such as regularity and frequencies of defecation, fecal form, gastrointestinal diseases, psychological scores, self-assessment of physical status, exercise and alcohol drinking. 2) The association between the amount of fiber intake and bowel function was significant. This association was still significant, when the confounders such as disease of upper digestive system and alcohol drinking were controlled.

• Journal of Korean Clinical Nursing Research
• /
• v.21 no.1
• /
• pp.80-91
• /
• 2015

Purpose: This study aimed to identify the relationships among bowel function, health locus of control, anxiety, and depression in patient with rectal cancer. Methods: This study utilized a descriptive correlational design. Subjects were 200 rectal cancer patients who attended out-patient clinic in a colorectal cancer center. The study instruments included the scales for bowel function, health locus of control, anxiety, and depression. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, and Pearson's correlation coefficient. Results: The mean score of bowel function was $34.44{\pm}5.73$. The mean scores of internal HLOC, chance HLOC, doctor HLOC, and powerful others HLOC were $29.06{\pm}6.81$, $22.41{\pm}6.96$, $15.88{\pm}2.85$, and $10.72{\pm}4.68$ respectively. The mean scores of anxiety and depression were $4.49{\pm}3.95$ and $6.25{\pm}3.98$, respectively. There were significant negative correlations between bowel function and anxiety (r=-.180, p=.011); between bowel function and depression (r=-.267, p<.001); and between internal health locus of control and depression (r=-.149, p=.035). There were significant positive correlations between chance health locus of control and depression (r=.146, p=.039), and between anxiety and depression (r=.651, p<.001). Conclusion: It is suggested that anxiety and depression for the patients with low bowel function after colorectal cancer surgery should be evaluated and nursing interventions to enhance internal health locus of control need to be developed.

• The Journal of Internal Korean Medicine
• /
• v.29 no.3
• /
• pp.666-674
• /
• 2008

Objectives : The aim of this study was to evaluate gastrointestinal parasympathetic nerve activation and pyloric valve function in patients with functional dyspepsia through analysis of bowel sounds and to investigate clinical characteristics associated with the parameters of bowel sounds. Method : We surveyed clinical characteristics of patients by using a questionnaire about functional dyspepsia. Bowel sounds were recorded for 15 minutes during fasting state and for 40 minutes during postprandial state. We then classified the patients into 3 groups by abnormal states of bowel sounds, specifically by the percentage of B.S. and dominenet frequency, and studied clinical characteristics in each group. Results : Among the 182 subjects, patients who had low activity of parasympathetic nerve were 25.8% and showed a tendency of female-dominant, family history and more frequent abdominal pain. Those who had pyloric valve disturbance were 24.1% and showed no tendency by sex distribution, family history and complained of indigestion sensation. Patients who had both disorders were 10.9%, and their clinical characteristics were non-specific. Conclusion : Analysis of bowel sounds may be useful in evaluating pathophysiological factors of functional dyspepsia.

• Women's Health Nursing
• /
• v.9 no.3
• /
• pp.277-286
• /
• 2003

Purpose: The purpose of this study was to probe the effect of foot reflexology education program on nursing students with constipation, anxiety and depression. This study was a quasi-experimental study of pre-test and posttest design on non-equivalent control group. Method: The data of this study were collected from October 28, to December 14, 2002. The subjects consisted of 61 nursing students (experimental group: 31, control group: 30) with constipation, anxiety and depression. 31 out of them were devided into the experimental group and received foot reflexology education program that was authorized by the World Foot Reflexology Association and made to suit for the subjects by the author for 6weeks composed of 2 weeks theory and of 4 weeks practical skill on the program. The effect of the program was measured by Bowel Function Assessment Form for constipation, State Anxiety Inventory, and Beck Depression Inventory. Data were analyzed by t-test, $x^2$-test, Repeated measures ANOVA, Bonferroni multiple comparison using SAS/PC 8.12 program. Result: After all session of treatment, the score of bowel function assessment were significantly decreased in the experimental group compared to the control group. Outcomes of 6 and 7 weeks were significantly different from those of pre-experiment. After all session of treatment, anxiety states were significantly decreased in the experimental group compared to the control group. Outcomes of 7 weeks were significantly different from those of pre-experiment. After all session of treatment, depression states were significantly decreased in the experimental group compared to the control group. Outcomes of 6 and 7 weeks were significantly different from those of pre- experiment. Conclusion: The results are suggested that the foot reflexology education program might improve the bowel function, anxiety and depression for the nursing students with constipation, anxiety and depression.

• Journal of Korean Academy of Nursing
• /
• v.51 no.6
• /
• pp.732-745
• /
• 2021

Purpose: This study aimed to assess combined effects of early oral feeding after Cesarean section (C/S) under regional anesthesia on bowel function, gastrointestinal complications and surgical recovery. Methods: A systematic literature search was conducted using KISS, RISS, PubMed, CINAHL, EMBASE, CENTRAL and Google Scholar to identify randomized clinical trials comparing early oral feeding (EOF) with delayed oral feeding (DOF) after C/S. Outcome variables were bowel function and gastrointestinal complications and surgical recovery. Effect size was calculated using weighted mean differences (WMDs) and relative risks (RRs), with 95% confidence intervals (CIs). Results: Seven studies involving 1,911 patients from 568 studies, 7 studies were included in meta-analysis. EOF was significantly associated with shorter time to recover bowel movement compared with DOF (WMD, - 2.50; CI, - 3.50~- 1.50). EOF was not associated with nausea (RR, 1.15; CI, 0.87~1.53) and vomiting (RR, 0.96; CI, 0.65~1.42), but lower incidence of abdominal distension (RR, 0.70; CI, 0.50~0.98). EOF was significantly associated with shorter time to discontinuation of intravenous fluids (WMD, - 8.88; 95% CI, - 16.65~- 1.11) and removal of urinary catheter (WMD, - 15.23; CI, - 25.62~- 4.85). Conclusion: This meta-analysis provides evidence that EOF after C/S under regional anesthesia not only accelerates return of bowel function and surgical recovery but also reduces gastrointestinal complications. These results suggest that EOF should be offered to women who have undergone C/S to improve the recovery experience and reduce overall medical costs.

• The Journal of Internal Korean Medicine
• /
• v.29 no.3
• /
• pp.621-628
• /
• 2008

Objectives : The aim of this study was to investigate changes of gastric vagal nerve activity and pyloric valve function after execution of combination treatments of both electroacupuncture at Zusanli(ST36) and manual acupuncture at other acupoints in patient with functional dyspepsia. Methods : Bowel sounds of 49 patients (18 male, 31 female) were recorded and their % of bowel sound (%BS) and ratio of dominant frequency (DF) were analyzed. Postprandial %BS was used to indicate the gastric vagal activity after eating. Ratio of postprandial/fasting dominant frequency was used to present the degree of pyloric valve function. According to values of %BS and DF ratio, each patient was classified into normal or abnormal (<6 %BS, hypoactivity: <1 DF ratio, dysfunction) group. For 2 weeks, patients received a treatment consisting of both electroacupuncture stimulation at Zusanli (ST36) and acupuncture at other meridian points. Variation of parameters shifting normal to abnormal or abnormal to normal was observed, and total cure rate was calculated. Results : Total cure rate of %BS was 16%, and that of DF was 37%. Patients who improved to normal value from abnormal or aggravated to abnormal level showed both significant difference in both vagal nerve hypoactivity and pyloric valve dysfunction, respectively. Conclusions : Analysis of bowel sound might be useful to evaluate both gastric vagal nerve activity and pyloric valve function. Combination effects of Zusanli (ST36) electroacupuncture and manual acupuncture of other acupoints showed a bidirectional effect in which their activity and function were in general improved. sometimes from aggravated to abnormal level.

• Bioinformatics and Biosystems
• /
• v.2 no.2
• /
• pp.71-74
• /
• 2007

Cell phenotypes are determined by groups of functionally related genes. Microarray profiling of gene expression provides us response of cellular state to its perturbation. Several methods for uncovering a cellular network show reliable network reconstruction. In this study, we present reconstruction of genetic regulatory network of inflammation bowel disease in human peripheral blood mononuclear cell. The microarray based on Affymetrix Gene Chip Human Genome U133 Array Set HG-U133A is processed and applied network reconstruction algorithm, ARACNe. As a result, we will show that inferred network composed of 450 nodes and 2017 edges is roughly scale-free network and hierarchical organization. The major hub, CCNL2 (cyclin A2), in inferred network is shown to be associated with inflammatory function as well as apoptotic function.

• Clinical and Experimental Pediatrics
• /
• v.51 no.11
• /
• pp.1136-1139
• /
• 2008

The genitourinary tract and gastrointestinal system are interdependent but share the same embryological origin, pelvic region, and sacral innervation. Although children with voiding disturbances often present with bowel dysfunction, this coexistence was considered coincidental until recently. However, it is now accepted that dysfunction in emptying of both systems is interrelated. Afferent impulses carrying sensory information are transmitted through the spinal cord and brainstem toward several cortical and subcortical areas, resulting in conscious control of the bladder and bowel. Alteration in these afferent pathways can result in dysfunction, including urinary and fecal incontinence. Distal gastrointestinal tract problems such as constipation might induce an inhibitory rectovesical reflex that interferes with normal voiding. Therefore, lower urinary tract function seems to be closely associated with distal gastrointestinal tract function.

• Nutrition Research and Practice
• /
• v.15 no.4
• /
• pp.411-430
• /
• 2021

Irritable bowel syndrome (IBS) is a frequently diagnosed gastrointestinal (GI) disorder characterized by recurrent abdominal pain, bloating, and changes in the stool form or frequency without any structural changes and overt inflammation. It is not a life-threatening condition but causes a considerable level of discomfort and distress. Among the many pathophysiologic factors, such as altered GI motility, visceral hypersensitivity, and low-grade mucosal inflammation, as well as other immunologic, psychologic, and genetic factors, gut microbiota imbalance (dysbiosis), which is frequently found in IBS, has been highlighted as an etiology of IBS. Dysbiosis may affect gut mucosal homeostasis, immune function, metabolic regulation, and even visceral motor function. As diet is shown to play a fundamental role in the gut microbiota profile, this review discusses the influence of diet on IBS occurring through the modulation of gut microbiota. Based on previous studies, it appears that dietary modulation of the gut microbiota may be effective for the alleviation of IBS symptoms and, also an effective IBS management strategy based on the underlying mechanism; especially because, IBS currently has no specific treatment owing to its uncertain etiology.