• Title, Summary, Keyword: comedone

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Biochemical Properities, Isolation & Identification of the Propionibacterium acnes Picked from Acne Lesion (여드름병변에서 채취한 Propionibacterium acnes의 분리, 동정 및 생화학적 특성 연구)

  • Lee, Kyung-Suk;Choi, Jeung-Sook
    • Fashion & Textile Research Journal
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    • v.8 no.5
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    • pp.571-576
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    • 2006
  • Thirty P. acnes were isolated from the 30 acne patients who visited some skin care shops from Feburary of 2001 to August of 2001. They were identified by morphological features (gram stain), biochemical properties. Only P. acne strains are isolated among Propionibacteria sp. and biochemical properities of P. acnes were not different from P. acnes ATCC 11827 strain significantly. The results of the biotyping was as follow: twenty three strains of biotype I from comedone, 1 strain of biotype II from pauple, 5 strains of biotype III from pauple and pustule, and 1 strain of biotype IV from pauple were isolated respectively.

A Clinical Report On 25 Years-old Female Patient With Acne In U.S.A Through Chung-We Mix Extract Powder, Houttuyniae Herba Extract And Comedone Extractor

  • Yoon, Jaehong
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.17 no.3
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    • pp.287-295
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    • 2013
  • Objectives This study is report the effect of Asian Medical treatments for acne. Methods 25 years old mixed Hispanic female in California resident patient who was suffering from acne was treated with the Chung-We mix Extract powder, Houttuyniae Herba Extract and comedone extractor. She was taken a picture to compare with before and after treatments. Results Her acne was decreased and global acne grading system by 35 points to 7point improvement on the after treatments. Conclusion This case has the effectiveness with Herbs. According to Asian medicine, the caused of acne is internal problems and the acne is diagnosed as several kind of heats in the internal organ. Further clinical case of acne is needed for better results and to develop the ways of accurate diagnosis.

Multiple Large Cysts Arising from Nevus Comedonicus

  • Jeong, Hii-Sun;Lee, Hye-Kyung;Lee, Seung-Hyun;Kim, Hyoung-Suk;Yi, Sang-Yeop
    • Archives of Plastic Surgery
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    • v.39 no.1
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    • pp.63-66
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    • 2012
  • Nevus comedonicus is a type of hamartoma that arises from a developmental anomaly of the mesodermal part of the pilosebaceous gland. In most cases of nevus comedonicus, an acne-like skin condition develops. Repeated inflammation can cause a morphological change to the cyst, papule, to abscess. We experienced a case of congenital nevus comedonicus, which led to the formation of large multiple cysts. A 50-year-old man was referred with a $12.5{\times}10cm$ lobulated mass on the posterior neck and upper back. The patient had a widespread presence of nevus comedonicus in the region ranging from the right superior chest to the posterior neck. The patient had a 30-year history of six prior excisions. A magnetic resonance imaging review led to a diagnosis of nevus comedonicus. Surgical treatment consisted of excision of the mass and wide excision for the patch type of nevus comedonicus around the neck. On histopathology, multiple masses were diagnosed as typical cysts containing keratinized tissue. The diffuse comedone lesions were diagnosed as nevus comedonicus. This case shows that large, multiple cysts can occur as a long-term complication of nevus comedonicus, and also highlights the importance of radical resection to prevent its further invagination.

Efficacy and Safety of Topical Application of Epidermal Growth Factor (EGF) for Korean Acne Patient (한국인 여드름 환자에서 표피성장인자가 함유된 외용제의 피부 적용에 대한 유효성 및 안전성 평가)

  • Suh, Joon Hyuk;Hyun, Moo Yeol;Jang, Seong Eum;Choi, Sun Young;Kim, Myeung Nam;Kim, Beom Joon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.2
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    • pp.111-118
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    • 2016
  • Acne vulgaris is a chronic inflammatory condition characterized by comedo, papule, cyst, nodule and postinflammatory hyperpigmentation. Meanwhile, it is also induced by adverse event of drugs. Among them, acneiform folliculitis is a side effect of epidermal growth factor receptor (EGFR) inhibitor, which is an anticancer agent, and its incidence may occur in upward of 75 ~ 100% of cases. The main method of acne vulgaris treatment is oral antibiotics, retinoids, topical medication and so on. However, it is limitation that teratogenicity caused by retinoids and antibiotic resistance increased by using antibiotics. In this study, we aimed to evaluate the clinical efficacy and safety of topical recombinant human (rh) EGF in treating facial acne vulgaris. Twenty three Koreans (age: 10 ~ 29 years) with mild to moderate acne vulgar participated in the study and applied topical rhEGF cream (trouble control EGF) with 3 products (trouble control clarifying cleansing foam, trouble control all-clear filling toner, redroll calming moisture) on their face twice daily for four weeks. Several assessment methods were applied: Acne lesion counts score by investigator's global assessment, efficacy and satisfaction score by subjects. Skin sebum output level, hydration level and redness level were also measured at each visit. At the final visit, skin sebum level, transepidermal water loss, skin redness statistically decreased and acne lesions (comedone, papule) were statistically reduced. No severe side effects were observed during the study. In conclusion, topical rhEGF seems to be an effective and safe adjuvant treatment option for mild acne vulgaris.