• The Journal of Korean Medicine
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• v.33 no.3
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• pp.105-119
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• 2012

Background: In contrast to the increased interest in constitutional medicine evidenced by clinical experiences, there has been no theoretical or mathematical analysis on the stability or number of constitutional types. Objectives: The purpose of the study was to evaluate the stability of possible constitutional types and to find stable constitutional types based on imbalanced structure of five energy elements using mathematical analysis. Methods: For the 120 constitutional types which are possible by the imbalanced combination of five energy elements, vitality, stability and continuity were evaluated mathematically based on mutual activation and suppression between the five energy elements. Results: 10 constitutional types were derived. They had the highest vitality and stability, and they had permanent continuity, never changing their order of imbalanced structure. Conclusions: 10 constitutional types are logical and most reasonable when we classify the body types based on imbalanced structure of five energy elements.

• Journal of Sasang Constitutional Medicine
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• v.29 no.2
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• pp.182-201
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• 2017

Objectives Gait disorders are incapacitating symptoms of Parkinson's disease(PD). Here, we report improvements of patients diagnosed with PD treated by Sasang Constitutional Medicine, focused on gait and balance analysis. Methods The patients diagnosed with PD were treated on the basis of Sasang Constitutional Medicine, and their stance and gait status were analyzed by zebris Medical GmbH. To evaluate other general symptoms related with PD, GAS scale, NRS scale, H&Y scale and UPDRS were used. Results Stride length, velocity, stance phase, lateral symmetry were improved in all 6 patients. Other symptoms related to Parkinson's disease were reduced, along with the improvements in GAS scale, NRS scale, H&Y scale and UPDRS score. Conclusion This case study showed Sasang Constitutional Medicine is effective in various symptoms of Parkinson's disease. Especially in regard to the stance and gait status, the improvements were assessed accurately with Gait analysis.

• Journal of Sasang Constitutional Medicine
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• v.35 no.4
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• pp.10-22
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• 2023

Objectives The aim of this study is to explore the mechanism of action and target diseases of Sasang constitutional prescriptions using a multiscale interactome approach. Methods The compound and target information of Sasang constitutional prescriptions were retrieved from various databases such as the TM-MC, STITCH, and TTD. Key targets for Sasang constitutional prescriptions were identified by selecting the top 100 targets based on the number of simple paths within the constructed network. Diffusion profiles for Sasang constitutional prescriptions and diseases were calculated based on a biased random walk algorithm. Potential diseases and key mechanisms of Sasang constitutional prescriptions were identified by analyzing diffusion profiles. Results We identified 144 Sasang constitutional prescriptions and their targets, finding 80 herbs with effective biological targets. A cluster analysis based on selecting up to 100 key targets for each prescription revealed a more cohesive grouping of prescriptions according to Sasang constitution. We then predicted potential diseases for 62 Sasang constitutional prescriptions using diffusion profiles calculated on a multiscale interactome. Finally, our analysis of diffusion profiles revealed key targets and biological functions of prescriptions in obesity and diabetes. Conclusions This study demonstrates the effectiveness of a multiscale interactome approach in elucidating the complex mechanisms and potential therapeutic applications of prescriptions in Sasang constitutional medicine.

• Journal of Sasang Constitutional Medicine
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• v.34 no.2
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• pp.36-47
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• 2022

Objectives The purpose of this study was to systematically review previous studies on constitutional herbal medicine treatment for the obesity. Methods A total of 11 databases were searched in English, Chinese, and Korean. Standard methodologies for the systematic review were used to search, analyze and synthesize data for undertaking review and meta-analysis for intervention. The risk of bias was assessed by two independent researchers using the Cochrane risk of bias. Results A total of 2 RCTs were selected and analyzed. The results of the meta-analysis showed a significantly positive effect in the body weight and body mass index for the patient group treated with Taeeumjowi-tang compared to the placebo control group. Conclusions Our results suggested that Taeeumjowi-tang could be considered for improvement of symptoms in obese patients, without serious adverse events. Due to the low quality of the clinical evidence in this study, further studies are needed to evaluate efficacy and safety of constitutional herbal medicines for obesity.

• Journal of Sasang Constitutional Medicine
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• v.21 no.2
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• pp.107-114
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• 2009

1. Objectives : We analyzed the case reports published by the journal of Sasang Constitutional Medicine, to study Sasang Constitution diagnosis and characteristic of clinical practice. 2. Methods : It has been examined 138 case reports of Sasang Constitution society published from 1994 to 2008. We analyzed. patient's number, publication year, distribution of Sasang Constitution, title's characteristics and bases of constitution diagnosis. 3. Results and conclusions : 1) In the analysis of patient's number, 1 case report was almost part of the case reports, and the case reports ware many published after 2001. 2) In the analysis distribution of Sasang Constitution, Soyangin was the most Sasang Constitution, and Tae-umin was the next one and Soeumin, Taeyangin followed them. 3) In the analysis of the journal's title, Sasang Constitution, disease and symptom of Sasang Constitution were more important than prescription recently. 4) In the analysis of the journal's purpose, unique disease and response of treatment were almost part of the case reports. 5) In the analysis of diagnosis bases, subjective bases were more important than objective bases and Sasang Constitutional drug response. therefore we should do researches in objective bases and drug response in the future.

• Journal of Sasang Constitutional Medicine
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• v.17 no.1
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• pp.33-44
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• 2005

1. Objectives The purpose of this study is to analysis that one's constitutional medicine can be used as another's medicine or not. Using the results of this study, it will improve to understand sasang constitutional medicine. 2. Methods In Lee Je-Ma's writings - GaboGubon ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$ and ShinChukbon ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$-, I analysis that one's constitutional medicine can be used as another's medicine. 3. Results and conclusions 1) In early stages of Lee Je-Ma's writings, there are several cases that one's constitutional medicines could be used as another's. But as days goes by, there are lesser cases that one's constitutional medicines could be used as another's. 2) In Lee Je-Ma's writings, there are few mixing of medicines with other constitutions. But, that have no fIxed standards such as book kind, constitution and others. 3) In Lee Je-Ma's writings, there are some mixing of medicine with other constitutions in cases of imperfections, experiences and modifications. 4) In Lee Je-Ma's writings, there are not permissions mixing of medicine with other constitutions in cases of side effects, obstructions and efficiencies.

• Journal of Sasang Constitutional Medicine
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• v.24 no.3
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• pp.42-49
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• 2012

Objectives This study aimed to assessing the performance of Sasang constitutional analysis Tool (SCAT) for Chinese as one of method to diagnose Sasang Constitution and evaluating the possibility of applying SCAT to foreign people. Methods This cross-sectional study was approved by IRB (Independent Review Board) at J Hospital in Yanbian. Informed consent to take part in the study was obtained from each of the participants. The performance of SCAT was assessed through Kappa coefficient and the concordance rate between SCAT and expert diagnosis. Results The concordance rate between SCAT and expert was 61.1% in total and the Kappa was 0.408. When the constitutional probability increased, the concordance rate and Kappa showed a increasing tendency. The concordance rate of Chosun race was 62.1% and others 60.7%. Conclusions SCAT, as Sasang constitutional diagnostic supporting system, may help the expert to diagnose Sasang constitution in Yanbian region.

• Journal of Sasang Constitutional Medicine
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• v.22 no.3
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• pp.67-74
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• 2010

1. Objectives: The research papers published by researchers in other fields except Oriental medicine were analyzed to study the research trends and characteristic of Sasang Constitutional medicine. 2. Methods: Systematic searches were performed on KISS, RISS, KISTI and DBPIA and finally 123 papers were selected. The publication year, research field of the first author, title's characteristic, research topic and the classification method of Sasang Constitution were investigated. 3. Results and conclusions: 1) In the analysis of publication year, the number of studies on Sasang Constitution has increased dramatically since 2000. 2) In the analysis of the first author's research field, physical training, nursing, engineering and food and nutrition were the majority. 3) In the analysis of the research topic, the classification method of Sasang Constitution was the majority. 4) In the analysis of the classification method of Sasang Constitution, QSCC II was the most popular method accounted for 68% and interview by specialist of Sasang Constitutional medicine accounted for 42%.

• Journal of Sasang Constitutional Medicine
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• v.14 no.2
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• pp.35-43
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• 2002

This study was performed to examine a clinical application of the QSCC II (Questionnaire for the Sasang Constitution Classification II) In this study, the subjects were 218 patients whose constitutions were differentiated at the Wonkwang Kwangju Oriental medical hospital. The results are as follows: 1. QSCC II were given to 218 patients after they were examined by the specialists in the Sasang constitutional medicine and received herbal formulas specific to their constitution. The constitutional analysis made by the specialists were then compared to the results of the questionnaire. The result showed only 51% agreement. 2. We made a frequency analysis of 121 questions and found that 85 questions had low statistical significance (P>0.2). 3. As a result, we have found that there is a limitation in differentiating the constitution by the questionnaire. Thus, in order to raise the statistical significance of the constitutional analysis, we hope that more suitable questionnaire will be developed for the future research.

• Journal of Sasang Constitutional Medicine
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• v.30 no.3
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• pp.40-47
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• 2018

Objectives The purpose of this study is to analyze the factors contributing to the classification of Sasang Constitution using Sasang Constitutional Analysis Tool 2. Methods A total of 99 subjects were assessed for the classification of Sasang Constitution using four measurement factors (face, voice, body shape, and questionnaire information) of Sasang Constitutional Analysis Tool 2. Results Taeeumin had significantly higher body weight and BMI. In the result of the agreement between the judgment of the four measurement factors and the final judgment of Sasang Constitution, the agreement degree of Soeumin was the highest value of 2.6. Taeeumin, Soeumin, and Soyangin showed the highest agreement with the individual judgment of face, body shape and questionnaire, and body shape, respectively. Conclusions It is difficult to conclude that any individual factor contributes significantly to the classification of Sasang Constitution. Further study on Sasang Constitutional Analysis Tool 2 involving more peoples is needed in order to determine the factors contributing to the classification of Sasang Constitution.