• 제목/요약/키워드: cross-over study

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Statistical Analysis of Bioequivalence Study in 2x3 Cross-over Design

  • Lim, Nam-Kyoo
    • Communications for Statistical Applications and Methods
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    • 제8권2호
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    • pp.443-452
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    • 2001
  • The 2x3 cross-over design is proposed for the bioequivalence of two test drug formulations with a reference drug formulation. Oh et al.(1999) and Park et al.(1998) derived 3x2 cross-over design and discussed its benefits, since the 3x3 cross-over design may not be of practical design. We discuss the statistical issues for2x3 cross-over design and show its statistical properties. Bioequivalence problem in 2x3 cross-over design is considered statistically and an illustrated example is given.

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A Longitudinal Study on Adolescent's Multicultural Acceptability and School Adjustment using Autoregressive cross-lagged model

  • Kim, Hyun-Joo;Park, Hwie-Seo
    • 한국컴퓨터정보학회논문지
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    • 제24권7호
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    • pp.153-160
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    • 2019
  • This study aims to analyze the mutual influences between adolescents' multicultural acceptability and school adjustment. Research problems for research are as follows. First, is multicultural acceptability and school adjustment stable over time? Second, what is the longitudinal impact of school adjustment on multicultural acceptability over time? Third, what is the longitudinal impact of multicultural acceptability on school adjustment over time? The results of analyzing the research problems by applying the autoregressive cross-lagged model are as follows. First, the autoregressive model of school adjustment has a significant effect on the future time point and is stable over time. Second, the autoregressive model of multicultural acceptability have a significant effect on the future time point and is stable over time. Third, cross-lagged effect from school adjustment to multicultural acceptability has a statistically significant effect on the multicultural acceptability at a later time, and is stable over time. Fourth, cross-lagged effect from multicultural acceptability to school adjustment was not statistically significant at the time of multicultural acceptability, and there was no change with time. This study is meaningful to provide the theoretical and practical implications by verifying the influence of the three - year term data over time.

PREFERRED ORIENTATION OF TIN FILM STUDIED BT A REAL TIME SYNCHROTRON X-RAY SCATTERING

  • Je, J.H.;Noh, D.Y.
    • 한국표면공학회지
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    • 제29권5호
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    • pp.399-406
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    • 1996
  • The orientational cross-over phenomena in an RF sputtering growth of TiN films were studied in an in-situ, real-time synchrotron x-ray scattering experiment. For the films grown with pure Ar sputtering gas, the cross-over from the more strained (002)-oriented grains to the less strained (111)-oriented grains occurred as the film thickness was increased. As the sputtering power was increased, the cross-over thickness, at which the growth orientation changes from the <002> to the <111> direction, was decreased. The addition of $N_2$ besides Ar as sputtering gas suppressed the cross-over, and consequently resulted in the (002) preferred orientation without exhibiting the cross-over. We attribute the observed cross-over phenomena to the competition between the surface and the strain energy. The x-ray powder diffraction, the x-ray reflectivity, and the ex-situ AFM surface topology study consistently suggest that the microscopic growth front was in fact always the (002) planes. In the initial stage of growth, the (002) planes were aligned to the substrate surface to minimize the surface energy. At later stages, however, the (002) growth front tilted away from the surface by about $60^{\circ}$ to relax the strain, which caused the cross-over of the preferred growth direction to the <111> direction.

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충돌분사의 충돌각 변화에 따른 난류특성의 실험적 연구 (An Experimental Study on the Turbulence Characteristics of a Cross Jet with Respect to Cross Angle Variations)

  • 노병준;최진철;강신재
    • 대한기계학회논문집
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    • 제13권5호
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    • pp.991-998
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    • 1989
  • 본 연구에서는 충돌각을 변수로 한 실험적 연구를 수행하기 위하여 여타의 변수를 고정하였으며, 유속은 R$_{e}$=5.2*$10^{4}$의 결과를 제시하였다.

한·중 크로스오버 쇼퍼들의 모바일 앱 충성도에 대한 탐색적 연구 (Mobile app Loyalty of Cross-over Shoppers: A Comparison of Korean and Chinese)

  • 박은주;구진;박신영
    • 한국의류산업학회지
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    • 제20권3호
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    • pp.293-303
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    • 2018
  • Since 2009, consumers could access a new shopping channel called 'mobile shopping' with the generalization of smartphones. Mobile shopping (based on wireless communication technology), emphasizes convenience differentiated from internet shopping. A recent report introduced fashion products as powerful global drivers for mobile shopping sales. Korea and China have the highest percentage of consumer mobile shopping experiences compared to other countries. This study investigates the effects of cross-over shopping orientation, perception of app attributes, and flow on app loyalty that compared Korean and Chinese consumers. We obtained 652 usable questionnaires from two local college students; subsequently, data were analyzed by using factor analysis, Cronbach's alpha, and regression analysis using SPSS 21.0 Package. The study results showed that the cross-over shopping orientation affected perception of app attributes that included Review/Information, Design, Response and Product. Product only affected Flow, which reflected a high similarity between Korean and Chinese consumers. However, Korean and Chinese consumers showed remarkable differences in the factors related to app loyalty. Therefore, the results indicate that retailers of fashion products have developed strategies to improve mobile sales and increase the app loyalty of cross-over shopping orientation consumers.

Nonparametric Tests for 2×2 Cross-Over Design

  • Gee, Kyuhoon;Kim, Dongjae
    • Communications for Statistical Applications and Methods
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    • 제19권6호
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    • pp.781-791
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    • 2012
  • A $2{\times}2$ Cross-over design is widely used in clinical trials for comparison studies of two kinds of drugs or medical treatments. This design has many statistical methods such as Hills-Armitage's (1979) method or Koch's (1972) method. In this paper, we propose a nonparametric test for $2{\times}2$ Cross-over design based on a two-sample test suggested by Baumgartner et al. (1998). In addition, a Monte Carlo simulation study is adapted to compare the power of the proposed methods with those of previous methods.

The Role of L1 and L2 in an L3-speaking Class

  • Kim, Sun-Young
    • 비교문화연구
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    • 제24권
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    • pp.170-183
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    • 2011
  • This study explored how a Chinese college student who previously had not reached a threshold level of Korean proficiency used L1 (Chinese) and L2 (English) as a tool to socialize into Korean (L3) culture of learning over the course of study. From a perspective of language socialization, this study examined the cross-linguistic influence of L1 and L2 on the L3 acquisition process by tracing an approach to language learning and practices taken by the Chinese student as a case study. Data were collected through three methods; interview protocols, various types of written texts, and observations. The results showed that the student used English as a means to negotiate difficulties and expertise by empowering her L2 exposure during the classroom practices. Her ways of using L2 in oral practices could be characterized as the 'Inverse U-shape' pattern, under which she increased L2 exposure at the early stage of the study and shifted the intermediate language to L3 at the later stage of the study. When it comes to the language use in written practices, the sequence of "L2-L1-L3" use gradually changed to the "L2-L3" sequence over time, signifying the importance of interaction between L2 and L3. However, the use of her native language (L1) in a Korean-speaking classroom was limited to a certain aspect of literacy practices (i.e., vocabulary learning or translation). This study argues for L2 communication channel in cross-cultural classrooms as a key factor to determine sustainable learning growth.

패널자료의 무응답 대체법 (Non-Response Imputation for Panel Data)

  • 박기덕;신기일
    • Communications for Statistical Applications and Methods
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    • 제17권6호
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    • pp.899-907
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    • 2010
  • 무응답 대체(non-response imputation) 방법에 관한 많은 이론과 방법이 제안되었으며 실제 자료 분석에 이용되고 있다. 흔히 횡단면 무응답 대체를 위하여 다중대체법(multiple imputation)이 사용되고 있으며 2차년도 이상의 패널자료에는 종시점회귀대체법(cross-wave regression imputation)이 사용되고 있다. 본 연구에서는 패널자료 분석을 위하여 종시점회귀대체법의 일반형태인 시계열 대체법과 횡단면 무응답 대체법을 결합한 시계열-횡단면 다중 대체법을 제안하였다. 노동부의 매월노동통계 자료를 이용하여 제안한 방법과 기존의 종시점회귀대체법을 비교하여 우수함을 보였다.

인장강도 1200 MPa 급 자동차 서브 프레임의 합금성분 최적화 및 열변형 거동 연구 (A Study on Dimensional Change after Heat Treatment and Optimal Chemical Composition of Steels with 1200 MPa Tensile Strength for Automotive Subframe)

  • 정우창
    • 열처리공학회지
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    • 제33권3호
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    • pp.107-116
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    • 2020
  • Four air hardening steels with carbon, silicon, manganese, chromium, and molybdenum variations have been used in this study to find out the optimal chemical compositions of steels with over 1200 MPa tensile strength for automotive subframe. The dimensional changes after heat treatment were determined for two automotive parts with open and closed cross sections using 3D scanner. When four steels were austenitized at 900℃ for 30 seconds, cooled at 3℃/s, reheated to 450℃ for 10 seconds followed by air cooling to simulate hot-dip galvanizing treatment showed ultra high tensile strength over 1200 MPa. Rear floor cross member with open cross section revealed much bigger dimensional changes than subframe with closed cross section after heat treatment at 900℃ for 20 minutes followed by air cooling.

아음속 횡단 유동장으로 펄스 분사된 액체 제트의 분무특성 (Spray Characteristics of a Pulsed Liquid Jet into a Cross-flow of Air)

  • 이인철;변용우;구자예
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2008년도 춘계학술대회논문집
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    • pp.61-64
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    • 2008
  • The present study of these experiments are close examination of spray characteristics that are continuous liquid jet and modulated pressure pulse liquid jet. The experiments were conducted using water, over a range of cross-flow velocities from 42${\sim}$136 m/s, with injection frequencies of 35.7${\sim}$166.2 Hz. Between continuous cross-flow jet and pressure pulsed cross-flow jet for characteristics of penetration, breakup point, spray angle and macro spray shape are investigated experimentally. In cross-flow field, main parameter of liquid jet for breakup was cross-flow stream rather than pressure pulse frequency. As oscillation of the periodic pressure that could make liquid jet moved up and down, the mixing efficiency was increased. Also, a bulk of liquid jet puff was detected at upper field of liquid surface. So, this phenomenon has a good advantage of mixing spray from concentration of center area to outer area. Because of pressure pulsation frequency, an inclination of SMD for the structured layer was evanescent. Cross-sectional characteristics of SMD at downstream area were non-structured distributions. Then cross-sectional characteristics of SMD size were about same tendency over a range that is effect of spray mixing. The tendency of volume flux value for various frequency of pressure pulse was same distribution. And volume flux was decreased when the frequency of pressure pulse increase.

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