• Journal of Digestive Cancer Research
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• v.10 no.2
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• pp.99-106
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• 2022

Clinical research ultimately aimed to promptly diagnose and prevent diseases through precise biomarker development. Finding the optimal cut-off point of a regularly measured biomarker can help its interpretation and ultimately help in disease investigation and diagnosis, more specifically in determining the presence of diseases. Therefore, this study aimed to use the characteristics of outcome variables in clinical research to explain how to determine the optimal cutoff point. The outcome variables can be divided into dichotomous, ordinal, and survival types. The optimal cut-off point can be determined by finding points that maximize the Youden index, extended Youden index, and log-rank statistics. This study will enable clinical researchers to accurately determine the optimal cut-off points for regularly measured biomarkers, thereby enabling prompt disease diagnosis for effective treatment.

• Journal of Environmental Health Sciences
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• v.47 no.4
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• pp.320-329
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• 2021

Background: Smoking exposure may be objectively assessed through specific biomarkers. The most common biomarker for smoking is cotinine concentration in urine, and setting an optimal cut-off point can accurately classify smoking status. Such a cut-off point for Korean adolescents has never been studied. Objectives: The aim of this study was to determine a cut-off point for urinary cotinine concentration for the discrimination of smoking in adolescents. Methods: Participants were adolescents aged 13~18 years who participated in the third cycle of the Korean National Environmental Health Survey. We used urine samples to confirm the level of cotinine concentrations. Smoking status was determined by self-reported questionnaire. We identified the optimal cotinine cut-off point for discriminating smoking status using receiver operating characteristic curve analysis. Results: Of the 904 participants, 28 (3.1%) were smokers, among whom 20 (71.4%) were male. The median urinary cotinine concentrations in smokers was 218 ㎍/L (male: 215 ㎍/L, female: 303 ㎍/L), and that in non-smokers was 1.31 ㎍/L (male: 1.46 ㎍/L, female: 1.18 ㎍/L). We found significant differences in urinary cotinine concentration according to smoking status and sex (p<0.001). Urinary cotinine concentrations performed well for identifying smoking adolescents [area under the curve: 0.954 (male: 0.963, female: 0.908)]. The cut-off that optimally distinguished smokers from non-smokers was 39.85 ㎍/L (sensitivity: 89.3%, specificity: 97.4%). Male [39.85 ㎍/L (sensitivity: 90.0%, specificity: 94.9%)] had a different optimal cut-off point than female [26.26 ㎍/L (sensitivity: 87.5%, specificity: 99.6%)]. Conclusions: This study determined a cut-off point for urinary cotinine of 39.85 ㎍/L (male: 39.85 ㎍/L, female: 26.26 ㎍/L) to distinguish smokers from non-smokers in adolescents.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.9B
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• pp.1690-1696
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• 1999

Video sequence should be hierachically classified for the content-based retrieval. Cut detection algorithm is an essential process to classify shots. It is generally difficult for cut detection algorithms to detect cut points since a current frame is compared with a previous one, because movement of camera or object made adrupt scene change. We reduce ratio of failed cut detection so that compare the difference between frames of predicted cut point and their neighbors. In this paper, first we get predicted cut point, then we judge that the predicted cut point is true point or not. And we extracted DC images in MPEG video sequence for comparison. As a result of experiments. We confirmed that the cut detection ratio of the proposed algorithm is higher than of any other algorithms.

• Proceedings of the Korean Society for Language and Information Conference
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• 2007.11a
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• pp.126-135
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• 2007

We propose and test several computational methods to automatically determine possible saliency cut-off points in Sketch Engine (Kilgarriff and Tugwell, 2001). Sketch Engine currently displays collocations in descending importance, as well as according to grammatical relations. However, Sketch Engine does not provide suggestions for a cut-off point such that any items above this cut-off point may be considered significantly salient. This proposal suggests improvement to the present Sketch Engine interface by calculating three different cut-off point methods, so that the presentation of results can be made more meaningful to users. In addition, our findings also contribute to linguistic analyses based on empirical data.

• Journal of Broadcast Engineering
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• v.15 no.6
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• pp.845-852
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• 2010

Collecting statistics from client requests, the broadcast server partitions data items into hot and cold-item sets with the optimal cut-off point. Hot items are broadcast periodically with periods based on their access probabilities. In a time slot with no hot items scheduled, the server broadcasts a proper cold item considering the waiting time and the number of outstanding requests. We analyze the optimal the cut-off point by calculating average response time as a function of the cut-off point. Simulation results show that our proposed algorithm outperforms existing methods in various circumstances.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.05a
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• pp.901-904
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• 2002

The cutting thickness of ultra-precision machining is generally very small, only a few micrometer or even down to the order of a flew manometer. In such case, a basic understanding of the mechanism on the micro-machining process is necessary to produce a high quality surface. When machining at very small depths of cut, metal flow near a rounded tool edge become important. In this paper a finite element analysis is presented to calculate the stagnation point on the tool edge or critical depth of cut below which no cutting occurs. From the simulation, the effects of the cutting speed on the critical depths of cut were calculated and discussed. Also the transition of the stagnation point according to the increase of the depths of cut was observed.

• Journal of Biosystems Engineering
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• v.34 no.4
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• pp.228-233
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• 2009

In order to cut the round bale easily, a roughage cut-feeder for the round bale was developed in this study. This study consists of two parts. One is development of a cutting mechanism and a performance test reported in the previous paper. This is the second part of the study. For the study, recent trend of traditional cutting system was analyzed. Also, cost of the prototype cut-feeder was analyzed and determine the break-even point of farm size was determined by comparing with traditional method using a traditional cutter. A prototype cut-feeder was investigated with the fact that working performance, fiber length and shape of roughage and feeding quality was good. Operating cost of the prototype cut-feeder decreased rapidly with an increase of farm size. Break-even point in terms of farm size was 36 heads for beef and 28 heads for dairy. Also, costs estimated were 118,000 won/head year and 148,000 won/head year, respectively.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.18 no.5
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• pp.27-36
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• 2015

This study was conducted to grasp the effect of afforestation of cut slope using coir blocks on the improvement of scenery and the management of non point pollution source. Total four experimental tanks such as general soil slope, coir blocks, installation slope, slope refilling the inside of coir blocks slope with pebble, slope refilling the inside of coir blocks with soil and plant were installed, pollution source water was supplied and the possibility of reduction management of non point pollution source was analyzed at four items of COD, SS, T-N, T-P and main results drawn from this study are as follows. In conclusion, biodegradable materials like coir blocks and soil and plant layers are judged to be helpful in reduction management of non point pollution source inflowing to water space from land area. Thus, the reduction of non point pollution source occurring at land area is thought to be fully controlled at the cut slope, the space prior to inflowing to water ecological space like a stream or a swamp area.

• Journal of the Korean Society for Precision Engineering
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• v.19 no.8
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• pp.126-133
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• 2002

The cutting thickness of ultra-precision machining is generally very small, only a few micrometer or even down to the order of a few nanometer. In such case, a basic understanding of the mechanism on the micro-machining process is is necessary to produce a high quality surface. When machining at very small depths of cut, metal flow near a rounded tool edge become important. In this paper a finite element analysis is presented to calculate the stagnation point on the tool edge or critical depth of cut below which no cutting occurs. From the simulation, the effects of the cutting speed on the critical depths of cut were calculated and discussed. Also the transition of the stagnation point according to the increase of the depths of cut was observed.

• Communications of the Korean Mathematical Society
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• v.26 no.1
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• pp.115-124
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• 2011

In this paper, some fuzzy fixed point theorems for fuzzy mappings are established by considering the nonempty closed $\alpha$-cut sets. Some importance observations are also discussed. Our results clearly extend, generalize and improve the corresponding results in the literatures, which have given most of their attention to the class of fuzzy sets with nonempty compact or closed and bounded $\alpha$-cut sets.