• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2003년도 춘계학술대회
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• pp.148-148
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• 2003

This study is to investigate the environmental levels and trend of dioxins, which was the 3$\^$rd/ year of environmental monitoring research for endocrine disrupting chemicals since 1999. Total 282 samples were analyzed from 115 sites including 26 sites of airs, 43 sites of waters, 11 sites of sediments and 35 sites of soil, which were the same as those of investigated sites in 2000. Sampling period was from June 2001 to June 2002. Target chemicals were seventeen species of 2,3,7,8-chlorine-substituted PCDD and PCDF congeners and were analyzed by the standard methods, established by National Institute Environmental Research (NIER). The average concentration of dioxins in air decreased from 0.324 pg-TEQ/N㎥ in 2000 to 0.287 pg-TEQ/N㎥ in 2001, and those in water and soil were 0.073pg-TEQ/L and 1.703pg-TEQ/dry g, respectively, which was the less values detected in 2000. In sediment, however, the value was 0.086pg-TEQ/dry g, which was the increase from the value of the year 2000. The concentration range of dioxins in air for 26 sites in 17 regions detected were 0.013∼l.664pg-TEQ/N㎥, 4 sites from those were exceeded the Air Quality Standards of Dioxin in Japan (0.6 pg-TEQ/N㎥). The tolerable daily intake of dioxins was calculated at the highest level (1.664) in air, with referring the soil and food data from Japan, was calculated to be 2.85pg-TEQ/kg/day, which was below the level of 4 pg-TEQ/kg/day suggested in KFDA(Korea). While the average concentration of dioxins in 15 big cities was 0.190 pg-TEQ/N㎥, that in 8 medium/small cities constituting an industrial complex was 0.558 pg-TEQ/N㎥. In water, the concentration range detected were 0∼0.946pg-TEQ/L and the trend of the average concentrations shows an increase from those of 1999 but decreased from those of 2000, any sites however were not exceeded the Water Quality Standards of Dioxin in Japan (1 pg- TEQ/L). In soil. the detected range were 0∼43.333 pg-TEQ/dry g and the average concentration decreased, compared with the results of 2000. According to the monitoring results by land utilization, the detected range were 0∼43.333pg-TEQ/dry g in farmland, 0.017∼0.601 pg-TEQ/dry g in the industrial area, 0.005∼0.049pg-TEQ/dry g in the park and 0.008∼1.825 pg-TEQ/dry g in the rest. In sediment, the detected range increased from 0∼0.244 pg-TEQ/dry g to 0∼0.537 pg-TEQ/dry g, based on the results of 2000. For the proper control of dioxins, continuous monitoring needs to be performed and in addition, the dioxin inventory should be prepared for major sources through the dioxin emission survey. These results would provide sound and solid basis for proper decision making of dioxins management like establishment of environmental quality standards in Korea.

• 한국물환경학회지
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• 제24권6호
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• pp.758-766
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• 2008

먹는물 처리 전후 다이옥신류의 동족체 패턴 및 제거율을 평가하기 위해서 42개의 일본 정수처리장에서 2년간 122개의 시료를 채취해 dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) 및 coplanar polychlorinated biphenyls (Co-PCBs)를 분석하였다. 다이옥신류의 평균 농도와 독성등가값 (toxic equivalent, TEQ)은 원수와 처리수에서 각각 60.24 pg/L (0.14 pg-WHO-TEQ/L), 4.15 pg/L (0.016 pg-WHO-TEQ/L)였다. 먹는물의 다이옥신류 기여 농도는 일일섭취량 (tolerable daily intake (TDI), 4 pg-TEQ/kg/day)의 0.016%이었다. 정수처리에 의한 다이옥신류의 평균 TEQ 제거율은 88% 이상이었다. 그러나 112개의 샘플에서 2, 3, 7, 8-TeCDF (tetrachlorodibenzofuran)의 농도는 17% 증가하였다. 따라서, 2, 3, 7, 8-TeCDF의 농도에 영향을 미치는 공정을 파악하기 위하여 고도정수처리 및 일반정수처리에서의 제거율을 조사하였다. 다이옥신 동족체(congener)인 TeCDF와 non-ortho-PCB는 고도처리 및 표준정수처리에서 염소소독처리 후 TEQ 농도가 증가함을 보여, 먹는물 중 2, 3, 7, 8-TeCDF 농도는 염소소독처리에 의해 상승한 것으로 밝혀졌다.

• 분석과학
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• 제13권5호
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• pp.675-682
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• 2000

생활폐기물 처리용량이 일일 50톤 이상인 소각시설에 대한 배출가스중의 다이옥신 농도는 신규시설인 경우 $0.1ng-TEQ/Nm^3$, 기존시설인 경우 $0.5ng-TEQ/Nm^3$로 규제하고 있으며, 기존시설인 경우에도 2003년에는 $0.1ng-TEQ/Nm^3$로 강화할 예정이다. 이들 소각시설은 다이옥신 측정분석기관으로부터 년 2회 이상 배출가스중의 다이옥신 농도를 측정하여야 한다. 현재까지 7개 기관이 다이옥신 측정분석기관으로 지정을 받았으며, 이들 기관은 매년 국립환경연구원이 제공하는 정도관리 프로그램에 따라 평가를 받아야 한다. 1999년에는 1998년에 지정받은 4개 기관에 대하여 M 소각시설에서 대기오염공정시험방법에 따라 다이옥신 시료채취 및 분석을 하여 정도관리를 실시하였다. 정도관리 실시결과 등속흡인계수는 각각 100.9%, 102.4%, 102.1%, 99.2%로 4기관 모두 양호하였으며, 분해능 (10,000 이상), 질량검정 결과(${\pm}5ppm$ 이내), 동위원소 존재비 (15% 이내) 및 회수율(50-120%) 모두 대기오염공정시험방법 기준을 만족하였다.

• Toxicological Research
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• 제17권
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• pp.323-327
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• 2001

March 19, 1999, the renovation qf the runway of the Bo-Fai ai1field in Hua Hin, Prachubk-erikhan, Thailand, unearthed chemicals which were left over from the project "anch Hand Operation" held during the Vietnam war era. The chemical mixtures were analyzed by the US EPA, the Department oj Medical Sciences (DMSc), Ministry oj Public Health (MoPH) and the Pollution Control Department (PCD), the Ministry oj Science Technology and Environment (MOSTE) of Thailand, The samples were found to contain several defoliants used in the operation. They were 2,4-D, 2,4,5-T, Dicamba, Cocydelic acid, and Dioxins. Due to the complexity of the issue, the multiplicity of possible health effects, and the socio-economic implications for imports and exports, the Thai Society of Toxicology submitted a proposal to request World Health Organization (WHO), Geneva. The assistance is for the area of chemical safety and called for immediate action to explore the magnitude qf risk involved with Dioxins. In this paper we present our approach to health risk assessment which takes into an account the epidemiological studies of high-risk group exposed to the Ranch Hand operation. Dioxins are endocrine disruption chemicals which public concerns are developed due to presumption that a hazard exists (www.eva.gov/dioxins/html) for which current methodologies are deemed insufficient. The recent concepts of how oxidative stress toxicants may affect health end points and biomarkers of exposure of exposed individuals are discussed. While research activities are undergoing, The Thai Society of Toxicology do not anticipate significant risk to local residents and the environment due to our concurrence with opinion from the international experts invited by the World Health Organization proposed to the local experts at a workshop in Bangkok.n Bangkok.

• 한국식품영양과학회지
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• 제37권3호
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• pp.325-332
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• 2008

본 연구에서는 식생활 양상이 서로 다를 것으로 생각되는 어촌, 농촌, 도시 지역별 각각 213명, 193명, 187명을 대상으로 직접면담과 24시간 회상법에 의한 식사섭취조사를 실시한 후 35가지 식품 중 다이옥신 함량 자료를 이용하여 추정한 다이옥신 섭취상태를 비교 평가하였다. 지역별 조사대상자의 평균 연령은 어촌 61.5세, 농촌 57.6세, 도시 49.4세 순으로 유의하게 높았으며, 신장은 도시 대상자가 160.0 cm로 어촌의 158.1 cm나 농촌의 157.7 cm보다 유의하게 높았다. 지역별 남녀 성별 분포는 유의한 차이가 없었다. 1일 에너지 섭취량은 농촌 1707.7 kcal, 도시 1596.5 kcal, 어촌 1493.8 kcal로 농촌이 어촌보다 유의하게 높았다. 1일 총 식품섭취량은 지역별 유의한 차이가 없었으나 어패류는 어촌 지역이, 곡류, 채소류, 육류, 조미료류는 농촌지역이, 당류, 두류, 난류, 해조류, 우유류, 유지류는 도시지역이 가장 높았다. 35종 식품의 다이옥신 함량자료를 이용하여 평가한 어촌, 농촌, 도시 대상자의 1일 다이옥신 섭취량은 어촌이 0.70 pgTEQ/kg/day로 농촌의 0.32 pgTEQ/kg/day나 도시의 0.46 pgTEQ/kg/day보다 유의하게 높았다. 곡류, 두류, 채소류, 어패류를 통한 다이옥신 섭취량은 어촌이, 난류와 우유류를 통한 다이옥신 섭취량은 도시가 가장 높았다. 전체 대상자의 다이옥신 섭취량은 육류, 난류, 어패류, 유지류, 조미료류 및 총 식품섭취량과 각각 유의한 정의 상관관계를 보였다. 이상의 연구결과를 종합할 때 식품을 통한 다이옥신 섭취량은 어촌 지역이 농촌이나 도시보다 높고 어패류나 동물성식품을 통한 섭취가 높았으나, 세 지역 모두 우리나라 내용(耐容) 1일 섭취량보다 낮아 안전한 수준이었다.

• Bulletin of the Korean Chemical Society
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• 제19권6호
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• pp.617-618
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• 1998

A simple and reproducible pretreatment method was developed for the determination of dioxins in milk sample. Liquid-liquid extraction (LLE) was used for the initial extraction of the analyte from milk. For the elimination of interferences coextracted from milk, acid treatment followed by multilayer silica gel, and then alumina column clean-up were performed. The clean extract could be obtained without carbon column or high performance liquid chromatographic (HPLC) clean-up procedure. Polychlorinated biphenyles (PCBs) and dioxins were separated on neutral alumina activated at 180 ℃ for 12 hours. The final extract was analyzed by HPLC and high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS). The recovery of dioxins spiked in milk at 75-300 ppt level was 83.3-98.9% and their relative standard deviation was 4.1-14%.

• Bulletin of the Korean Chemical Society
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• 제19권6호
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• pp.619-624
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• 1998

A simple and reproducible pretreatment method was developed for the determination of dioxins in milk sample. Liquid-liquid extraction (LLE) was used for the initial extraction of the analyte from milk. For the elimination of interferences coextracted from milk, acid treatment followed by multilayer silica gel, and then alumina column clean-up were performed. The clean extract could be obtained without carbon column or high performance liquid chromatographic (HPLC) clean-up procedure. Polychlorinated biphenyles (PCBS) and dioxins were separated on neutral alumina activated at 180 ℃ for 12 hours. The final extract was analyzed by HPLC and high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS). The recovery of dioxins spiked in milk at 75-300 ppt level was 83.3-98.9% and their relative standard deviation was 4.1-14%.

• 공업화학
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• 제8권5호
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• pp.790-795
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• 1997

일반적으로 독성물질의 전형으로 알려진 다이옥신은 다양한 경로로 발생하여 인간과 환경에 유입되지만 대부분은 연소과정에서 발생된다. 본 실험에서는 EPA 방법에 의해 쓰레기 소각 처리후 생성된 폐가스와 비산재에 함유된 다이옥신류의 분포형태를 조사하고, 보다 효율적인 시료채취와 전처리 방법을 살펴보았다. 가스시료는 등속흡인하여 포집하였으며, 전 처리시 고체, 액체시료는 각각 속실렛과 액-액 추출법으로 추출하고 실리카겔, 알루미나, 활성탄 칼럼으로 정제한 후 고분해능 가스크로마토그래피/질량분석기(HRGC/H-RMS)로 분석하였다. 굴뚝 배출가스의 등속흡인결과 상대오차율이 평균 96.5%로서 안정적으로 시료가 흡인되었음을 확인하였으며, 폐가스와 비산재에서 측정된 다이옥신과 퓨란류는 선진국과 유사한 패턴을 나타냈다. 굴뚝 배출가스중 다이옥신과 퓨랸의 양은 각각 $1076.20pg/Nm^3$과 $1452.34pg/Nm^3$으로 나타났다. 주로 염소원자 7~8개로 치환된 이성체가 많았으며, 독성이 가장 강한 2,3,7,8-TCDD는 $8.84pg/Nm^3$으로서 전체 양의 0.64%를 차지해 비교적 낮게 확인되었다.

• 한국산업보건학회지
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• 제26권3호
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• pp.277-285
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• 2016

Objectives: This study was performed in order to evaluate whether 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) could be detected among residents living near Camp Caroll in Waegwan and whether serum concentrations of dioxins, including 2,3,7,8-TCDD, and organochlorine pesticides (OCPs) are associated with length of residence. Methods: Study subjects totaled 113 (for dioxins) and 190 (for OCPs) adults who were selected from participants in a medical investigation. Serum concentrations of dioxins and OCPs were measured using HRGC/HRMS. Information on length of residence was obtained through questionnaires. Results: 2,3,7,8-TCDD was not detected in serum among all subjects. When length of residence was classified as a categorical variable, after adjusting for confounding variables, only residents living in Waegwan for 40 years or longer tended to have high total TEQ values and 2,3,4,7,8-PeCDF with marginal significances. There was no dose-response relation between length of residence and serum concentrations of these chemicals. In multiple regression models with continuous values of the length of residence, total TEQ value and 1,2,3,4,6,7,8-HpCDF were positively associated with length of residence. However, they explained about 3-5% of total variations of serum concentrations of these compounds, while age, consumption of fatty fish, body mass index, alcohol drinking, and cigarette smoking were main variables affecting serum concentrations of dioxins or OCPs. Conclusions: In the current study, high concentrations of certain compounds were mainly observed among persons who lived in Waegwan for at least for 40 years without a dose-response relation. Therefore, it seems difficult to conclude that length of residence meaningfully contributed to the current serum concentrations of dioxins or OCPs among residents in Waegwan. However, considering the half-life of 2,3,7,8-TCDD and indirect exposure routes, the limitations of the current study design should be considered in the interpretation of the study findings.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 2003년도 ISIS 2003
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• pp.334-337
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• 2003

The emission of dioxins from waste incinerators is one of the most important environmental problems today, It is known that optimization of waste incinerator controllers is a very difficult problem due to the complex nature of the dynamic environment within the incinerator. In this paper, we propose applying artificial neural networks to waste incinerator controllers. We show that artificial neural networks can project the emission of dioxins with a fair degree of accuracy.