• Journal of Environmental Health Sciences
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• v.24 no.2
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• pp.47-56
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• 1998

When rats are exposed to cadmium in their diet, the cadmium accumulates in the liver. This study was carried out to investigate the effect of chitin, chitosan and dithiocarbamate chitosan on the cadmium accumulation in liver of rats. For this experiment, 10 male Sprague-Dawley were used. The experimental groups were divided into four independent groups which were one control group and three experimental groups by cadmium alone treatment or chitin, chitosan and dithiocarbamate chitosan with cadmium. In order to investigate the eliminative effect of chitin, chitosan and dithiocarbamate chitosan on the cadmium accumulation in liver of rats, the cadmium concentration, the metallothionein level and the enzyme activitys were measured. The results obtained revealed the eliminative effect of cadmium in liver of rats by chitin, chitosan and dithiocarbamate chitosan. The effect of chitin on the cadmium elimination was less than that of chitosan and dithiocarbamate chitosan. Also it shows that the eliminative effect of cadmium by dithiocarbamate chitosan was the highest.

• Journal of Environmental Health Sciences
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• v.24 no.3
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• pp.107-113
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• 1998

This study was performed to investigate the effects of chitin, chitosan and dithiocarbamate chitosan on the cadmium accumulation in liver and kidney of catfish. The experimental groups were divided into four independent groups which were one control group and three experimental groups by cadmium alone treatment or chitin, chitosan and dithiocarbamate chitosan which cadmium. in order to investigate the effects of chitin, chitosan and dithiocarbamate chitosan on the cadmium accumulation in liver and kidney of catfish, the cadmium concentration, the metallothionein level were measured. The results obtained were as follows: 1. The cadmium concentrations in liver and kidney of catfish in cadmium alone treatment group were similar to that of the chitin treatment group, but chitosan and dithiocarbamate chitosan treatment groups were significantly decreased. 2. The metallothionein levels in liver and kidney of catfish alone treatment group were similar to that of the chitin treatment group, but chitosan and dithiocarbamate chitosan treatment groups were significantly increased. In conclusion, this study revealed the effect of chitin, chitosan and dithiocarbamate chitosan against cadmium accumulation in liver and kidney of catfish. It exhibited the highest effect at dithiocarbamate chitosan treatment group.

• Journal of Environmental Health Sciences
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• v.24 no.3
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• pp.26-34
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• 1998

Diethanolamine Dithiocarbamate containing OH groups which gave water-soluble [Pt(dtc)$_{2}$] (diethanolamine dithiocarbamate) were synthesized from the reaction of CS$_{2}$ with diethanolamine. The complex has been characterized by elemental analysis, electrical conductivity, and spectroscopic results. Diethanolamine dithiocarbamate is effective as rescue and inhibition of cis-[$Pt(NH_{3})_{2}Cl_{2}$] nephrotoxicity in rats. It is suggested that diethanolamine dithiocarbamare removes platinum(II) complex coordinated to -SH groups of protein of kidney tubule cells.

• The Korean Journal of Malacology
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• v.13 no.1
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• pp.65-70
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• 1997

This strdy was performed to investigate the effect of chitin, chitosan and dithiocarbamate chitosan against cadmium accumulation. The Scapharca subcrenata were divided into four independent groups which were one control and three experimintal groups by camium alone treatmint or chitin, chitosan and dithsan and dithiocabamate chitosan which cadmium. Samples were analyzed by Varian 30/40 atomic absorption spectrophotometer. The results obtained were as follows;1. The cadmium concentration in water were isgnificantly decreased in three experimental group compared with that of control group (P<0.05)2. The cadmium concentration in muscle of S. srbcrenata in cadmium alone treatment group were similar to that of the chitin treatmint group, but chitosan and dithiocarbamate chitosan treatmint groups were significantly decreased (P<0.05)In conclusion, this study revealed the effect of chitin chitosan and dithiocarbamate chitosan against cadmium accumulation. It exhibited the highest effect at dithiocarbamate chitosan treatment group.

• YAKHAK HOEJI
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• v.39 no.1
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• pp.48-54
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• 1995

Coupling of tetracycline(Tc) to dithiocarbamate chitosan(DTCC) via chelate bond was investigated varying reaction time, concentration, temperature, pH, and Ca(II)/Tc ratio. The amount of Tc bound to matrix increased to give a maximum and decreased as the reaction proceeded. The degree and rate of dissociation of Tc complex were affected by the reaction temperature, and pH. By running the reaction at low temperature and pH, the degree of dissociation was greatly diminished. Properties of drug-release from DTCC-Ca(II)-Tc complex were studied by batch- and flow-method and release of Tc and CA(II) by flow method followed nearly zero-order. DTCC-Ca(II)-Tc showed very prolonged antimicrobial activity compared to that of free Tc.

• Bulletin of the Korean Chemical Society
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• v.9 no.6
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• pp.365-368
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• 1988

Coordination chemistry of organotin(IV) dithiocarbamate complexes has been examined in terms of far infrared and $^{119}Sn$-NMR spectroscopies. Although the Sn-S stretching vibrational bands of the complex could not be correlated with the bonding nature of the dithiocarbamate ligand, $^{119}Sn$ chemical shifts were sensitive enough to distinguish clearly the coordination number of tin, and as such the bonding mode of the dithiocarbamate ligand could be indentified to be monodentate or bidentate. Thus the $^{119}Sn$-NMR study on new cyclohexyltin(IV) dithiocarbamate complexes along with the known complexes suggests that the bonding mode of the dithiocarbamate ligands and the consequent coordination number of tin are determined mainly by the inductive effects of the organic groups attached to the tin atom.

• Journal of the Korean Chemical Society
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• v.40 no.5
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• pp.302-307
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• 1996

Diethanolamine dithiocarbamate is known to react with dichlorobis(ethylenediamine)cohalt(Ⅲ) chloride to form [Co(dtc)3](dtc=diethanolamine dithiocarbamate) in which two sulfur atoms of the dithiocarbamate are bound to cobalt. The complex is moderately soluble in acetone, but sparingly soluble in carbon disulfide. Kinetics and mechanisms of the reaction of dichlorobis(ethylenediamine)cobalt(Ⅲ) chloride with diethanolamine dithiocarbamate have been studied in aqueous solution. Activation parameters have been calculated from the kinetic data for the reaction and from these results a possible mechanism for the reaction has been proposed.

• Journal of Environmental Health Sciences
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• v.34 no.4
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• pp.285-291
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• 2008

This study was performed to investigate the effects of Chitosan on the nickel poisoning in rats. In the study, 150 male Sprague-Dawley were used. The experimental groups were divided into four: A (30 mg/L nickel), B (30 mg/L nickel+0.2% Chitin, Chitosan and Dithiocarbamate Chitosan), C (30 mg/L nickel+0.4% Chitin, Chitosan and Dithiocarbamate Chitosan), D (30 mg/L nickel+0.8%Chitin, Chitosan and Dithiocarbamate Chitosan). The results were as flows; 1. The nickel concentration in the livers of the control group (A) was $0.153{\sim}0.186\;mg/kg$ but the nickel concentration in the livers of the experimental decreased during the experimental period (P<0.05). 2. Metallothionenin levels in rat liver were $2.77{\sim}3.25\;ug/g$ wet,wt in control group (A), but were $2.89{\sim}3.51\;ug/g$ wet,wt (B), $2.97{\sim}3.62\;ug/g$ wet,wt (C), $2.68{\sim}3.68\;ug/g$ wet,wt (D). Respectively in the experimental groups. The experimental groups were inclined to increase compare to the control group (P<0.05). In conclusion, this study revealed a preventive effect of Chitin, Chitosan and Dithiocarbamate Chitosan against nickel toxicity.

• Analytical Science and Technology
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• v.12 no.1
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• pp.1-6
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• 1999

Copper(II) complex of piperidine dithiocarbamate (Pipdtc) was synthesized from the reaction of Cu(II) and piperidine dithiocarbamate. The possible structure of the complex was proposed on the basis of elemental analysis, molar conductivity, infrared spectroscopy, electronic absorption spectroscopy, and $^{13}C-NMR$ studies. The extraction of copper(II)-Pipdtc complex by carbon tetrachloride can be achieved in the pH range of 6.0~10. The solution of copper(II) with piperidine dithiocarbamate was bey Beer's law in the concentration up to ${\sim}8.0{\times}10^{-5}M$ at pH 9.0.

• Bulletin of the Korean Chemical Society
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• v.34 no.7
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• pp.2044-2050
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• 2013

A series of poly(glycerol-succinic acid) dithiocarbamate and 1,3,4-thiadiazole dendrimers, which have potential as anti-wear oil additives, were synthesized. Their anti-wear properties in three different oils (100N, DB-51, and soybean) were evaluated using a four-ball wear tester. The results indicated that thiocarbamate dendrimers have moderate anti-wear properties in DB-51 oil, and 1,3,4-thiadiazole dendrimers exhibited good anti-wear properties in 100N and DB-51 oils. However, dithiocarbamate and 1,3,4-thiadiazole dendrimers were not effective anti-wear additives in soybean oil.