• Journal of Korean Elementary Science Education
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• v.33 no.3
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• pp.566-578
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• 2014

The purpose of this study is to develop a program for elementary school students' scientific experimental design knowledge generation. This study also investigated the effects of their experimental design ability, as well as the change in the type and elaborateness of their experimental design by applying the program. The subjects of this study was 4 classes in 6th grade of an elementary school located in Seoul, KOREA. The classes were divided into experimental and comparative groups. While the treatment was applied to the experimental group, the comparative group was taught using conventional methods. The pre-test and post-test for students' capability of building scientific experimental design knowledge were conducted to compare the ability of experimental design, the change in the type and elaborateness of experimental design. The findings in this study are as follows: First, the program appeared to be effective in improving experimental design ability. Furthermore, the program appeared to be more effective in generating a higher level of the experimental design type and elaborateness. Therefore, in order to improve experimental design knowledge generation ability, the program can be utilized as effective learning model in elementary school.

• Journal of Sasang Constitutional Medicine
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• v.4 no.1
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• pp.221-230
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• 1992

In order to investigate the effects of shipjuntaepotang (少陰人 十全大補湯) on immune response, the author performed this experimental study. Delayed type hypersensitivity (DTH) and rosette forming cells (RFC) for cell-mediated immune response, hemagglutinin (HA) titers, hemolysin (HL) titers, and carbon clearance for phagocytic function of MPS (mononuclear phagocyte system) were measured in ICR mice. The results were summarized as follows. 1. DTH in the experimental group was increased, as compared with the control group, with statistical significance. 2. RFC in the experimental group was increased, as compared with the control group, with statistical significance. 3. HA-titers were increased in the experimental group, as compared with the control group, with statistical significance. 4. HL-titers were increased in the experimental group, as compared with the control group, with statistical significance. 5. Carbon clearance was increased in the experimental group, as compared with the control group, with statistical significance. Through invivo experimental study in ICR mice, these findings suggest that shipjuntaepo-tang enhance both cellmediated and humoral immune responce.

• Journal of Korean Elementary Science Education
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• v.38 no.4
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• pp.475-483
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• 2019

The purpose of this study was to investigate the effect of brainwriting instruction on students' experimental design and scientific communication ability in elementary science class. For this purpose, a brainwriting learning for science class was developed and applied. The objects of this study were the 4th graders of both an experimental class (24 students) and a comparative class (24 students) at the N elementary school located in Incheon city. The results of the study were as follows; First, as a result of examining the difference in the experimental design ability between experimental group and comparative group, the experimental group showed higher than the comparative group, it was statistically significant difference(p<.05). Second, a scientific communication ability of the experimental group after applying this program was higher, it was statistically significant differences (p<.05).

• Journal of Korean Academy of Nursing
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• v.33 no.5
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• pp.659-667
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• 2003

Purpose: This study was done to develop an applicable training program for high school girls on sexual assertiveness. Method: The design combined methodological study and non-synchronized quasi experimental study designs. The participants were 174 high school girls from two schools. Two questionnaires were used, one consisted of 23 questions on self efficacy and the other, of 22 items on sexual assertiveness. The SPSS 10.0 program was used for data analysis. Experimental group 1(3 hour program) and experimental group 2(6 hour program) were received on sexual assertiveness. The sexual assertiveness program was carried out by members of the research team. There were no differences in demographic characteristics between control group, experimental group 1, and experimental group 2. Result: There was no significant increase in self efficacy scores in experimental group lover the control group, but there was a significant increase in sexual assertiveness scores in the experimental group lover the control group. There was an increase in self efficacy scores in experimental group 2 over the control group, but it was not significant. There was a significant increase in sexual assertiveness scores in experimental group 2 over the control group. There was no significant increase in self efficacy scores in the experimental group 2 over the experimental group 1, and there was no significant increase in sexual assertiveness scores in experimental group 2 over the experimental group I. Conclusion: The results show that a 3 hour program was as effective as a 6 hour program for sexual assertiveness. Therefore, it is advisable to use a hour program for clinical convenience. But further study is needed to determine the lasting effect on sexual assertiveness.

• Journal of the Korean Society of Physical Medicine
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• v.16 no.1
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• pp.83-92
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• 2021

PURPOSE: This study examined whether ankle joint stabilizing taping and muscle control taping influenced the ankle range of motion (ROM), muscle tone, and balance ability in chronic stroke patients. METHODS: Ten stroke patients were assigned randomly to experimental group 1 (joint stabilization taping n = 5) and experimental group 2 (Muscle control taping n = 5). After general physical therapy in both groups, ankle stabilization taping was applied to experimental group 1, and muscle control taping was applied to experimental group 2 three times a week for a total of six weeks (18 times). RESULTS: The muscle tone and stiffness of the gastrocnemius (GCM) showed significant differences between the experimental 1 and experimental 2 groups (p < .05). The Berg Balance Scale (BBS) and ROM also showed significant differences within the experimental 1 and experimental 2 groups (p < .05). The BBS and ROM also showed no significant differences between the experimental 1 and experimental 2 groups (p > .05). CONCLUSION: This study examined the muscle tone, balance, and ROM on the paraplegic side of stroke patients using kinesio taping, and the effect of the taping application method was confirmed from the preceding study. Therefore, it can decrease the paralysis side muscle tone and improve the ROM and balance ability.

• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.1
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• pp.113-127
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• 2015

Objectives: This study was performed to analyze the trend of acne-related experimental studies in Korean medicine. Methods: We searched 17 articles related with experimental study of acne, published Korean medical journals from 2005 to 2014. We classified all articles according to the journal and checked on the kind of herbs. All articles were categorized into two types: cell experimental study and animal experimental study. Results: 1. Total 17 papers were searched; 7 articles (41.2%) were published in the Journal of Korean Medical Ophthalmology, Otolaryngology, Dermatology, 4 articles (23.5%) were published in the Journal of Korean Institute of Pharmacopuncture, 3 articles (17.6%) were published in Korean Journal of Oriental Physiology and Pathology, 2 articles (11.8%) were published in Korean Journal of Herbology, and 1 article (5.9%) was published in the Journal of Korean Medicine. 2. Total 17 kind of herbs were used in the studies; 10 articles (58.8%) used single herb, 7 articles (41.2%) used complex herbs. 3. Total 17 articles were categorized 2 types; 16 cell experimental studies (94.1%), 1 animal experimental study (5.9%). 4. Experimental researches were mainly investigated using Raw 264.7 cell line and P. acnes. The levels of NO, iNOS, $TNF-{\alpha}$, PGE, COX-2, $IL-1{\beta}$, IL-6, NF-kB were analyzed to confirm of herbs' antibacterial, anti-inflammatory, antioxidant activity. Conclusions: Searching for natural antibiotics, it is needed to do experimental studies continuously, and also needed to diversify the kind herbs and experimental bacteria.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.15 no.3
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• pp.217-228
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• 1993

The purpose or this study was to observe the histological alteration of Langerhans cells on wound healing process in applying low energy laser irradiation. For this study, 50 Spraque-Dewly rats, weighing 150Gm or more were devided into control, experimental control group(0), 47.5Hz(1), 190Hz(3), 380Hz(5), 760Hz(7), lased group. All the experimental animals were made excision wound on buccal mucosa, 2mm depth, and lased with stoma laser (904nm, semconductor type ASGaAI, Sedalac France) 47.5Hz, 380Hz, 960Hz, 3minutes one time respectively except experimental control group. After the experiment, experimental animals were sacrificed after 24hours, 48hours, 72hours on each. Taken specimens were embedden in paraffin, sectioned 6-8u in thickness. And the langerhans cell were detected using ant S-100 protein antibody, and histochemically processed with Avidin Biotin complex method. All the Langerhan cells were calculated under light microspe in 400 multiplication field and standard deviation, probability test between each group were evaluated using statistical analysis system(S.A.S)program. Following results were obtained. 1. Langerhan cells were increased in experimental control group compared to that in control group(P<0.01). 2. 24hour after experiments, Langerhans cell were decreased compare to that in control group and control experimental group 5, 1, 3. Probability test shows significance between control experimental and 5, 1, 3 group on a =0.05 range. 3. 48our after experiment, Langerhans cells were decreased compare to that on experimental control group, and probability test shows significance between control experimental and 3, 7, 5 group an a=0.05 range. 4. 72hour after experiments, Langerhans cells were decreased compare to that on experimental control group and probability test on group comparison shows significance between control experimental and 1, 5 and 1 between 3, 7 between 3, and 5, between 7, respeilively on a=0.05 range. 5. Langerhans cells number in experimental group were decreased compare to that on experimental control group in applying laser irradiation.

• Advances in nano research
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• v.4 no.3
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• pp.167-179
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• 2016

The detailed study of acute and sub-acute toxicity of the complex polyvinylpyrrolidon (PVP 20 kDa)-wrapped fullerene $C_{60}$ after intraperitoneal (ip) administration was carried out on adult male Wistar rats. The $LD_{50}$ value of $C_{60}/PVP$ complex was found to be 7, 8 g/kg. In sub-acute study which lasted for 30 days the rats were exposed to daily administration of the complex in the doses of 350 or 700 mg/kg. All animals survived during the study and had no significant changes in clinical signs, organ weight, hematological and biochemical parameters of blood. The electrophysiological properties of myocardium and the excretory function of kidneys remained normal. Histological analysis of liver, kidney and spleen at the end of the study also did not demonstrate toxic alterations. It was thus established that intraperitoneal administration of complex $C_{60}/PVP$ has no toxic effect. These results suggest that $C_{60}/PVP$ has no acute and sub-acute toxicity and is a perspective substance for potential application in biology and medicine.

• Journal of East-West Nursing Research
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• v.8 no.1
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• pp.89-102
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• 2003

This study attempted to analyze the trend of studies related to IHD(Ischemic Heart Disease). This article reviewed 102 researches on IHD conducted from 1980 to 2003, by examining them according to their characteristics, such as sources by publication period, research design, nursing intervention, outcome of experimental research, and theme of qualitative research. The results were as follows : 1. The number of studies related to IHD has steadily increased year by year since 1985, and that of the articles was the highest during the post-2000 period. Especially, the majority of researches has published since 1995. 2. The 69 studies were degree of all 102 studies related to IHD, and the majority of articles' authors belonged to graduate school. Thirty three studies were non-degree articles. As for study design, the number of quantitative studies were 99 and that of qualitative studies were 3. Non-experimental research design were largely survey and correlational study. 3. Non-experimental study makes up a high proportion of the quantitative study. The most of experimental studies were accomplished after 2000. The main subjects were patients, chart records and general subjects. The majority number of subjects was like this : while the number of non-experimental study was between 51 and 100, that of experimental study was below 50. The number of subject of qualitative study is like this : the number of phenomenology study was 21 and 11, and that of case study is 14. 4. Nursing interventions used in the experimental study comprised teaching program, cardiac rehabilitation program, massage, relaxation, music therapy and providing of sense information. And the most nursing intervention effects included physiological effect, increased self-efficacy, relieved pain and increased quality of life. Most studies proved to have the affirmative effects. 5. The number of qualitative studies related to IHD is like this : the number of degree articles was 2 and that of non-degree articles was 1. Its themes included resources of hope, the experience of coronary artery angiography and the experience of admission at ICU(Intensive Care Unit).

• The korean journal of orthodontics
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• v.22 no.2 s.37
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• pp.427-447
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• 1992

The purpose of this study was to evaluate the effect of the lateral displacement on the mandibular condylar growth in the rabbit. The experimental animals were twenty White NewZealand rabbits of 4-week old. Ten of them was used as control group, and experimental animal was composed of remaining ten. Laterodeviation appliance was made of cast base metal and appliance was cemented with resin in permanent fashion. Experimental group were sacrificed at 1, 2, 4, 6, 8 weeks form beginning of the experiment. Both of temporomandibular joint were prepared for histologic study. The conclusions are: 1. In control group, there was slight increase of proliferative zone and hypertrophic zone at 2-week control animal and slight reduction at 4-week. 6-week and 8-week control animal were similiar to 1-week control animal. 2. In right mandibular condyle of experimental group, 2-week experimental animal showed marked increase of proliferative zone and hypertrophic zone at posterior surface of condylar head. In 8-week experimental animal marked increase at anterior surface of anticular surface is observed. 3. In left mandibular condyle of experimental group, proliferative zone and hypertrophic zone were reduced at 1-week experimental animal and slight increase at 2-week. Proliferative zone and hypertrophic zone were reduced at 4-week experimental animal and were slightly increased at 6 week. 4. After 8 weeks, right and left condyle were not different in experimental group. The condylar cartilage was stabilized 8 weeks after the experiment. No marked traumatic change was seen, but minute focal bleeding was seen at articular cavity in 1-week, 2-week and 4-week experimental animal. 6-week and 8-week experimental animal did not show bleeding tendency in articular cavity.