• Title, Summary, Keyword: fat mass

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The effect of thalidomide on visceral fat pad mass and triglyceride concentration of the skeletal muscles in rats

  • Kim, Ki-Hoon;Choi, Chang-Bon;Kim, Jong-Yeon
    • Yeungnam University Journal of Medicine
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    • v.35 no.2
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    • pp.213-218
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    • 2018
  • Background: Body fats, especially both of abdominal fat pad mass and skeletal muscle fat content, are inversely related to insulin action. Therefore, methods for decreasing visceral fat mass and muscle triglyceride content may be helpful for the prevention of insulin resistance. Methods: Thalidomide, used for its anti-angiogenic and anti-inflammatory properties, was administered to rats for 4 weeks. A 10% solution of thalidomide in dimethyl sulfoxide was injected daily into the peritoneal cavity as much as 100 mg/kg of body weight. Results: The total visceral fat pad mass in the thalidomide-treated group was 11% lower than in the control group. The size of adipocytes of the epididymal fat pad mass in the thalidomide-treated group was smaller than in the control group. The intraperitoneal thalidomide treatment increased triglyceride concentrations by 16% in the red muscle, but not in the white muscle. Conclusion: The results suggested that intraperitoneal thalidomide treatment inhibited abdominal fat accumulation, and that the free fatty acids in the blood were preferentially accumulated in the red muscle rather than in the white muscle.

Body composition by bioelectrical impedance analysis in children below 7 years old (7세 미만의 소아에서 생체전기저항법에 의한 체성분 분석)

  • Jung, Jiyoung;Kim, Han Wool;Kim, Tae Hyun;Hong, Young Mi
    • Clinical and Experimental Pediatrics
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    • v.53 no.3
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    • pp.341-348
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    • 2010
  • Purpose : Body composition is important to define and manage obesity and undernutrition. Obesity is a significant health problem with medical and psychological consequences for children and adolescents. Body composition analysis (BIA) is a simple, rapid, noninvasive, and reproducible technique. However, comparative analysis of body composition has not been done in young children below 7 years old. The aim of this study is to estimate antropometric data and body composition by BIA, and to investigate the correlation between anthropometric data and fat mass or fat percent in young children. Methods : We measured height, weight, body mass index (BMI), fat mass, and fat percent by BIA in 1,376 children aged 3-6 years of whom 688 were males and 688 were females. Results : Fat mass, fat percent, intracellular fluid, extracellular fluid, protein, and minerals were significantly higher in the obese group. A significant positive correlation exists between fat mass and BMI or weight. A significant positive linear correlation was also noted between fat percent and BMI. Protein, weight, fat mass, and fat percent were significantly different among groups. Conclusion : BIA is an objective, accurate method to estimate body fat in childhood obesity cases. Fat mass and fat percent data acquired by using BIA highly correlated with BMI. However, a large-scale study is needed to diagnose obesity in young children.

The Correlation between Flexi-bar Exercise and Trunk Muscles Strength and Body Composition in Juvenile Soccer Players

  • Wang, Joong San;Park, Si Eun;Shin, Hee Joon;Choi, Wan Suk;Kim, Hong Rae;Kim, Bo Kyoung;Park, Joo Hyun;Lee, Joon Hee;Min, Kyung Ok
    • Journal of International Academy of Physical Therapy Research
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    • v.6 no.1
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    • pp.781-787
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    • 2015
  • The purpose of this study is to verify a correlation between flexi-bar exercise and improvement of trunk strength and body composition in juvenile soccer players. The subjects were 11 teenager juvenile soccer players who conducted flexi-bar exercise half an hour daily three times a week for eight weeks. They were tested for trunk muscles strength, body composition and correlation. The result showed that trunk muscles strength improved significantly(p<.01) and weight, Rt. arm muscle mass, Rt. leg muscle mass, and Lt. leg muscle mass(p<.05), Lt. arm muscle mass, trunk muscle mass, and body muscle mass(p<.01) improved significantly as well while Lt. arm fat mass, Rt. leg fat mass, and Lt. leg fat mass decreased significantly(p<.05). In the correlation analysis, the more trunk muscle mass and trunk muscles strength increased, the more muscle mass of body regions increased, which was a positive correlation whereas fat mass of body regions decreased, which was a negative correlation. It was verified that there was a correlation between flexi-bar exercise and improvement of trunk muscles strength and body composition for juvenile soccer players.

A 8-Week, Randomized, Double-Blind, Placebo-Controlled Human Trial to Evaluate the Efficacy and Safety of Punica granatum L.·Actinidia chinensis Planch. Mixed Extract on Body Fat (석류·참다래 혼합추출물의 체지방 감소에 대한 유효성 및 안전성을 평가하기 위한 8주, 무작위 배정, 이중눈가림, 위약-대조 인체적용시험)

  • Choi, Jin-Bong;Lee, Ji-Eun;Do, Yun-Kyoung
    • Journal of Korean Medicine for Obesity Research
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    • v.17 no.2
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    • pp.87-95
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    • 2017
  • Objectives: This study was conducted to evaluate efficacy and safety of Punica granatum L. Actinidia chinensis Planch. mixed extract on body fat. Methods: Thirty women were recruited ($25kg/m^2{\leq}body$ mass index [BMI]${\leq}29.9kg/m^2$) ($19yr{\leq}age{\leq}38yr$) and randomized to receive Punica granatum L. Actinidia chinensis Planch. mixed extract or placebo for 8 weeks. During the test, they visited four times including screening. Body fat mass, body fat rate, anthropometric dimensions at waist and hip, waist-hip ratio, total cholesterol, triglyceride, low density lipoprotein-cholesterol (LDL-C), and high density lipoprotein-cholesterol (HDL-C) were measured at screening and 8 weeks after screening. Adverse reaction were also checked each visit. Results: There were no significant differences in all index. But when divide experimental group by BMI index, age, and compliance, less than BMI $27kg/m^2$ group decreased body weight, body fat mass and more than BMI $27kg/m^2$ group also decreased body weight, body fat mass and waist circumference. Less than age 30 years group showed decline of waist circumference, fat free rate and T-cholesterol and more than age 30 years group showed decline of fat free mass. Group with compliance more than 95% was decreased BMI, fat free mass, and hip circumference. Conclusions: There was no significant efficacy as compared with placebo group, but as divide experimental group according to BMI index, age, compliance, mixed extract might be effective to reduce obesity index.

A prospective study on changes in body composition and fat percentage during the first year of cancer treatment in children

  • Yang, Hye Ran;Choi, Hyoung Soo
    • Nutrition Research and Practice
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    • v.13 no.3
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    • pp.214-221
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    • 2019
  • BACKGROUNDS/OBJECTIVES: Cancer treatment may lead to significant body composition changes and affect growth and disease outcomes in pediatric cancer patients. This prospective study aimed to evaluate short- and long-term body compositions changes focused on body fat during the first year of cancer treatment in children. SUBJECTS/METHODS: A prospective study was conducted in 30 pediatric cancer patients (19 hematologic malignancies and 11 solid tumors) and 30 age- and sex-matched healthy controls. Anthropometric measurements and body composition analysis using whole body dual energy X-ray absorptiometry were performed at baseline and 1, 6, and 12 month(s) of cancer treatment. Kruskal-Wallis tests, Wilcoxon paired t tests, and generalized estimation equation (GEE) were applied for statistical analysis. RESULTS: At baseline, no differences in weight, height, body mass index, abdominal circumferences, body fat, and fat-free mass were observed between 30 controls and 30 pediatric cancer patients. Total fat mass (P < 0.001) and body fat percentage (P = 0.002) increased significantly during the first month, but no changes were observed from 1 to 12 months; however, no changes in the total mass were observed during the first year of cancer treatment. Meanwhile, the total fat-free mass decreased during the first month (P = 0.008) and recovered between 6 and 12 months of follow-up (P < 0.001). According to GEE analysis, there was a significant upward trend in body fat percentage during the first year, especially the first month, of cancer treatment in children with hematologic malignancies, but not in those with solid tumors. CONCLUSIONS: Our results indicate that cancer treatment is related to significant body composition changes and rapid body fat gain, particularly during the first month after initiating cancer treatment, in children with hematologic malignancies. Therefore, individualized dietary strategies to prevent excessive fat gain are needed in pediatric cancer patients for better outcomes.

Effects of Saengsig with Behavior Modification Therapy on Body Composition Changes in Obese Patients (행동수정을 병행한 생식이 비만인의 신체조성에 미치는 영향)

  • 김경남;박성호;홍서영;윤호준;김융기;송윤경;임형호;이영종
    • The Journal of Korean Medicine
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    • v.24 no.1
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    • pp.9-28
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    • 2003
  • Objects : The aim of this study was evaluate the effect of the Saengsig taken along with Behavior Modification Therapy, Methods : We examined the body compositions of 20 obese patients who were treated with Saengsig and Behavior Modification Therapy for 2 months by Inbody 2.0. Results : Changes of body composition due to Saengsig with Behavior Modification Therapy were reduction of body weight by $3.14{\pm}1.33{\;}kg$, lean body mass by $0.14{\pm}1.48{\;}kg$, fat mass by $3.00{\pm}1.53kg$ and BMI by $1.30{\pm}0.54$ Conclusion : Fat mass and body fat rate were significantly reduced after treatment with Saengsig with Behavior Modification Therapy.

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The analysis of body composition and bone mineral density in adult by using dual energy X-ray absorptiometry (이중에너지 방사선 흡수계측법(DEXA)을 이용한 성인들의 체구성과 골밀도 분석)

  • Lee Joong-chul;Han Sang-wan
    • The Journal of Korean Physical Therapy
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    • v.15 no.4
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    • pp.466-478
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    • 2003
  • This study was to evaluate the body composition and bone mineral density according to aging in adult and investigated the relationship between various parameters such as body mass index(BMI), bone mineral density(BMD), bone mineral content(BMC), lean body mass(LBM), fat mass(FM) and the value obtained from dual energy X-ray absorptiometry(DEXA). The subjects were composed of healthy adult male and female who were $20^{\sim}73$ years old and they were divided three group according to age (A group : 20-39 yrs., B group : 40-59 yrs., C group : more than 60 yrs.). The conclusion derived from statistical analysis was as follows : 1. Bone mineral content and density were significantly affected by lean body mass(relatively, R=0.85 - 0.63). 2. There was significant difference among age groups in total bone mineral density. 3. There was significant difference among age groups in bone mineral content of male and female. 4. Lean body mass is diminished according to age, but there was not significant difference among age groups. 5. Fat mass of A group in male had the highest mass and followed by C group and B group. In female groups, fat mass of A group had the highest mass and followed by B group and C group. Abdominal fat mass is increased according to age. This result suggest that aging was closely relation with loss of muscle mass, bone mineral density and bone mineral content.

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A Study on the Anthropometry and Healh-Related Lifestyle Habits of Women College Students in Kunsan (군산시 일부 여대생의 신체적 특성과 식생활 관련습관에 관한 연구)

  • 장혜순;김미라
    • Korean Journal of Community Nutrition
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    • v.8 no.4
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    • pp.526-537
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    • 2003
  • The purpose of this study was to compare the anthropometry and nutrition knowledge, food behaviour and lifestyle of women college students with different obesity indexes. The subjects were 251 women college students who were randomly selected from Kunsan National University. The height, body weight, soft/lean mass, fat mass, percentage of body fat, and fat distribution were measured, and health-related lifestyle habits were evaluated based on questionnaires. The subjects were assigned to one of the following groups based on their Body Mass Index (BMI) : underweight, normal weight and overweight. The results were as follows. Their body weight, soft/lean mass, fat mass, percentage of body fat, and fat distribution were significantly higher in the overweight subjects when compared to the underweight or normal weight subjects. Standard of living, self-recognition of health status and duration of exercise were significantly correlated with their BMIs. Self-satisfaction with body weight decreased as the BMI increased. Most subjects had poor habits such as skipping meals and lack of exercises. The overweight and the underweight groups skipped meals more frequently than the normal weight group. There were no significant differences in the scores on the nutritional knowledge and the dietary behaviour of the subjects with different BMIs. Therefore, proper nutritional education on regular meals and intervention are required if women college students are to have normal weights and healthy lifestyles. (Korean J Community Nutrition 8(4) L: 526∼537, 2003)

The Changes of Body Compositions after Modified Fasting Therapy: A Retrospective Observational Study (절식요법이 체성분 변화에 미치는 영향: 후향적 관찰연구)

  • Lee, Eun Jung
    • Journal of Korean Medicine for Obesity Research
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    • v.16 no.2
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    • pp.116-123
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    • 2016
  • Objectives: The purpose of this study was to investigate the effects of modified fasting therapy on the changes of body compositions. Methods: We analyzed the medical records of 33 patients, who carried out modified fasting therapy at Dunsan Korean Medicine Hospital of Daejeon University from January 1st, 2011 to December 30th, 2015. They went through reducing food intakes period (7 days), fasting period (14 days) and refeeding period (14 days). Body compositions (weight, body mass index, skeletal muscle mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) were reviewed at each state. And then the data was analyzed. Results: The body composition values (weight, body mass index [BMI], skeletal muscle mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) decreased during the fasting therapy period, as a whole. The weight, BMI, percent body fat and visceral fat area decreased during the reducing food intakes period, the fasting period and the refeeding period. The skeletal muscle mass and basal metabolic rate significantly decreased during the reducing food intakes period and the fasting period, and insignificantly increased during the refeeding period. Conclusions: Results from this investigation showed that modified fasting therapy using fermented herbal medicine have positive effects on changes of body compositions.

Correlation between Short Stature and Obese Degree - Intended for the Case of 236 Patient in the Name of Short Stature (저신장과 비만도의 상관성 분석 - 저신장을 주소로 내원한 환아 236명을 대상으로)

  • Lee, Kyung-Hee;Song, Jae-Chul;Lee, Jae-Sung;Kwak, Chang-Kyu;Park, Sun-Young;Han, Seung-Moo;Lim, Sa-Bi-Na;Shin, Hyun-Taeg
    • Journal of Korean Medicine for Obesity Research
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    • v.5 no.1
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    • pp.97-107
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    • 2005
  • Objectives The purpose of this study was to investigate correlation between short stature and obese degree. And we also wanted to know the characteristics of patients visited clinic in the name of 'short stature'. Methods Height, body weight, BMI, fat mass, lean body mass, percent body fat were taken intended for 236 patients in the name of short stature. To all the patient questionnaire for growth clinic was drawn up, and ultrasound scan was taken through calcaneous of the right foot. The patients were classified to three groups - short, average, tall group - according to relative position of mid-parental height. It was analysed that the differences between groups in obese degree. Also was investigated correlation between position of short stature and obese degree, and between obese degree and bony maturity. Results & Conclusion 1. The average ages of patients in the name of 'short stature' were $12.69{\pm}3.93$ years old in boys, $10.66{\pm}3.67$ years old in girls. And it seemed to be just before second rapid maturing period. 2. The average BMI were $20.58{\pm}4.07kg/m^2$ in boys, $18.65{\pm}2.85kg/m^2$ in girls, and average percent body fat were $21.99{\pm}7.35%$ in boys, $26.01{\pm}6.35%$ in girls. 3. The numbers of obese children were 34(31.2%) in boys, 19(14.9%) in girls on the basis of BMI. And the numbers were 39(35.8%) in boys, 53(41.7%) in girls on the basis of percent body fat. There was a big difference in case of girls. 4. The numbers of AG(average group) were 48(44.0%) in boys, 60(47.2%) in girls, the numbers of SG(short group) were 35(32.1%) in boys, 31(24.4%) in girls, and numbers of TG(tall group) were 26(23.9%) in boys, 35(27.6%) in girls. 5. There were no significant differences among the groups in BMI, lean body mass, fat mass, percent body fat. Only significant difference in DI(disease index). 6. There were no significant correlation between PH(percent height) and BMI, leanbody mass, fat mass, percent body fat. Only significant correlation in DI(disease index). 7. There were no significant differences between DA(difference between bone age and chronorogical age) and BMI, leanbody mass, percent body fat. Only significant correlation in fat mass.

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