• Asian Oncology Nursing
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• v.5 no.1
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• pp.31-39
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• 2005

Purpose: This study was to identify the levels of functional status, depression, family support and their relationship among those variables in head and neck cancer patients. Method: The subjects were 100 patients with head and neck cancer patients who visited at outpatients clinic in one university hospital in Taegu. The instrument used for this study were Functional Status in Head & Neck Cancer - Self Report Scale developed by Baker(1995), Self-Rating Depression Scale by Zung(1965) and Family support assessment tool by Kang hyun-suk(1984). The data were analysed percentage, mean, t-test, ANOVA and pearson's corelation using SAS program. Result: There was significantly negative correlation between functional status and depression(r=-.71) and between depression and family support(r=-.56). The relationship of functional status and family support was significant as r= .33. Conclusion: It was found that functional status, depression and family support of head and neck cancer patient were closely related each other. Therefore it is necessary to design nursing intervention to enhance family support or decrease depression for improving quality of life in head and neck cancer patient.

• Journal of Korean Academy of Nursing
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• v.45 no.6
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• pp.900-909
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• 2015

Purpose: The purpose of this study was to identify the effect of predictive factors related to family strength and develop a structural equation model that explains family strength among married working women. Methods: A hypothesized model was developed based on literature reviews and predictors of family strength by Yoo. This constructed model was built of an eight pathway form. Two exogenous variables included in this model were ego-resilience and family support. Three endogenous variables included in this model were functional couple communication, family stress and family strength. Data were collected using a self-report questionnaire from 319 married working women who were 30~40 of age and lived in cities of Chungnam province in Korea. Data were analyzed with PASW/WIN 18.0 and AMOS 18.0 programs. Results: Family support had a positive direct, indirect and total effect on family strength. Family stress had a negative direct, indirect and total effect on family strength. Functional couple communication had a positive direct and total effect on family strength. These predictive variables of family strength explained 61.8% of model. Conclusion: The results of the study show a structural equation model for family strength of married working women and that predicting factors for family strength are family support, family stress, and functional couple communication. To improve family strength of married working women, the results of this study suggest nursing access and mediative programs to improve family support and functional couple communication, and reduce family stress.

• Proceedings of the Korean Information Science Society Conference
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• 2006.06a
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• pp.13-15
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• 2006

microRNA는 유전자의 전사 후 과정에서 negative regulation을 담당하는 small noncoding RNA의 한 증류이다. 최근까지 330여개의 인간 microRNA가 발견되었지만 그들의 기능이 밝혀진 것은 소수에 불과하다. microRNA의 기능은 3'UTR에 불완전 상보결합을 통해 negative regulation을 받게 되는 유전자의 기능으로부터 유추되는 것이 일반적이다. 특별히 유전체상에 군집화 된 microRNA들은 하나의 전사체로부터 발현되는 것으로 판단되며, 같은 또는 관련된 기능을 하거나 같은 목표 유전자를 조절하기 위한 functional family일 가능성이 높다. 또한 이러한 functional family는 하나의 전사체로부터 발현되기 때문에, 조직별로 조건별로 같은 발현 패턴을 보여야 한다. 본 연구에서는 발현데이터로부터 microRNA functional family를 탐색하기 위해, 5개의 연구 그룹에서 공개한 조직별 microRNA 발현데이터를 표준화 작업을 거친 후 통합하고 k-nearest neighbor 알고리즘을 이용해 결측치를 보정한 후 microRNA 발현사이의 correlation을 계산한다. 이때 데이터 통합에서 생기는 문제에 robust한 결과를 얻기 위해 실제 발현데이터가 아닌 rank 데이터부터 correlation을 측정한다. 계산된 spearman ranked correlation 결과와 microRNA의 genomic coordination 정보로부터 34개의 functional family를 정의할 수 있었다.

• Journal of International Academy of Physical Therapy Research
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• v.9 no.2
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• pp.1475-1485
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• 2018

This study was conducted to examine the effects of the application of family-centered training over the 12-week period by the pediatric physiotherapist on functional balance and activities of daily living in children with cerebral palsy. Among the 26 children with cerebral palsy as the subjects were allocated to the experimental and control group. Both groups were subjected to neurodevelopmental treatment by the pediatric physiotherapist. The experimental group, participated in family-centered training program 3 times a week over a period of 12 weeks for the total of 36 sessions, functional balance and activities of daily living were verified through intergroup comparison. There was no significant difference between the outcomes prior to training and after 6 weeks of training, (p>.05) Pediatric Berg's Balance Scale(PBS) and Functional Independence Measure for children(Wee-FIM) increased significantly from those measures after 6 weeks to those after 12 weeks of training (p<.05). Therefore, these results suggest that on family-centered training on children with cerebral palsy has beneficial effects on functional movements and physical activities.

• Journal of Institute of Control, Robotics and Systems
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• v.13 no.3
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• pp.256-262
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• 2007

In mass customization, the focus is variety and customization through flexibility and quick responsiveness. Mass customizers seek to provide personalized, custom-designed products at low prices to give customers exactly what they want and to provide sufficient variety in products and services. The idea of the product family is the most adequate approach to realize mass customization. An understanding of customer needs using functional decomposition becomes necessary to enhance the performance of the product family. This paper focuses on functional architecture modeling based on customer need regarding sub-functions for the product family. A quantitative functional model captures product functionality and customer need. Based on customer need ratings and sub-function, a product-function matrix was created. Additionally, a product-product matrix was generated to provide a similarity index among product families. A case study for implementing the functional architecture modeling was performed on the single use cameras.

• Korean Journal of Child Studies
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• v.13 no.2
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• pp.145-160
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• 1992

The purpose of this study was to investigate the relationships between children's self-concepts and (1) types of functional family systems. (2) family cohesion and adaptability levels, and (3) the satisfaction of children with their current family systems. The subjects of this study were 347 middle S. E. S. children (168 boys, 179 girls) in grade 6. Analysis of functional family systems was by The Family Adaptability and Cohesion Evaluation Scales III(1985) of the Circuplex Model (Olson et al., 1979). The Self-concept Inventory (Lim Jae Leun, 1987) was used to assess children's self-concepts. The data were analyzed with one-way ANOVA, $Scheff{\acute{e}}$ and Pearson correlation. It was found that there were no differences in children's self-concepts by types of functional systems. There were differences in children's self-concepts by family cohesion and adaptability levels. That is, the higher the level of cohesion and adaptability the more positive the child's self-concept. The more the child was satisfied with his/her current family system, the more positive the child's self-concept. Children whose family systems were at a high level of family cohesion and adaptability were more satisfied with their current family systems.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.4 no.1
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• pp.87-101
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• 1997

This Research is an attempt to find out what effects the resistance exercise program has on the rheumatoid arthritis patient's functional disability and biochemical parameters. The research took place from June to November 1996, and the target included an experimental group of 25 cases of rheumatoid arthritis and a control group of 26 cases of rheumatoid arthritis taken from the Anam Medical Center at Korea University. The resistance exercise program was executed on these patients five times a week during a period of eight weeks. Before and after the experiments, measurements of functional disability score, ESR, CRP, self-efficacy, and family support were taken and closely analysed. The results of this analysis are as follows : 1. After the experiment, the experimental group had less functional disabilities compared to the control group(t=9.11, P=0.0017). 2. After the experiment, the ESR of both the experimental and the control groups decrease, but there was not notable difference between the two groups(t=0.07, P=0.9546). 3. After the experiment, the CRP of both the experimental and the control groups decreased, with no significant different between them(t=0.53, P=0.6022). 4. After the experiment, the self-efficacy of the experimental group increased significantly compared to the control group(t=3.15, P=0.0042), but the self-efficacy had no effect on the actual practice of the program. 5. After the experiment, the family support of the experimental group was higher than of the control group(t=6.33, P=0.0013), but again the family support had no effect on the actual practice of the program. Judging from the results of these experiments, the resistance exercise program not only diminishes rheumatoid arthritis patients' functional disabilities, but also has a great influence on increasing their self-efficacy and family support. Concluding, in diminishing the functional disabilities of rheumatoid arthritis, the resistance exercise program would be appropriate nursing intervention.

• Food Engineering Progress
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• v.21 no.1
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• pp.1-11
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• 2017

Dyslipidemia, defined as elevated triglyceride (TG), total- and LDL-C, and/or decreased HDL-C levels, is considered a principal risk factor for cardiovascular disease. The low-density lipoprotein receptor (LDLR) family has been considered a key player in the prevention of dyslipidemia. The LDLR family consists of cytoplasmic membrane proteins and plays an important role not only in ligand-receptor binding and uptake, but also in various cell signaling pathways. Emerging reports state that various functional ingredients dynamically modulate the function of the LDLR family. For instance, oats stimulated the LDLR function in vivo, resulting in decreased body weight and improved serum lipid profiles. The stimulation of LRP6 by functional ingredients in vitro activated the Wnt/${\beta}-catenin$ pathway, subsequently suppressing the intracellular TG via inhibition of SREBP1, $PPAR{\gamma}$, and $C/EBP{\alpha}$. Furthermore, the extract of Cistanchetubulosa enhanced the expression of the mRNA of VLDLR, followed by a reduction in the serum cholesterol level. In addition, fermented soy milk diminished TG and total cholesterol levels while increasing HDL-C levels via activation of LRP1. To summarize, modulating the function of the LDLR family by diverse functional ingredients may be a potent therapeutic remedy for the treatment of dyslipidemia and cardiovascular diseases.

• Korean Journal of Human Ecology
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• v.7 no.4
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• pp.55-69
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• 2004

The purpose of this study is to reduce the side effect of functional health foods. The research is done by in-depth interview method. The nineteen officials who worked in local administration or KFDA(Korea Food & Drug Administration) were interviewed. The questions were asked regarding the current status of consumer reports related to functional health foods, the problems which officials perceived, and the regulations required to reduce the problems. The findings are as follows: 1) the consumers report the side effect of functional health foods to nongovernmental organization. 2) officials feel that the problems are the difficulty in finding the cause of the side effect, unjust sale tactics, deceptive and small-sized manufacturers. and the distorted consumer conception on functional health foods. 3) officials think that improvement on the regulations are required to reduce the problems caused by the side effects. It includes the indication of the ingredient's origin and warnings considering physical conditions, close cowork between administration and nongovernmental organization. introduction of sales license for functional health foods and the increase of the opportunity for consumers to get information and education on functional health foods.

• Journal of Korean Academy of Nursing
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• v.17 no.3
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• pp.177-183
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• 1987

This study investigated and evaluated a method effectively promote a communication function in families with a schizophrenic patient and the patients' interaction, by a family approach using reinforcement of functional communication between patients and their parents. The subjects of the study were patients receiving treatment in Won Gwang University Mental Hospital from July 1985 to July 1986, and their families. In the experimental group, a family approach using reinforcement of functional communication twice a week was taught. Each of the six sessions took sixty minutes, during which the interviews and questionaires were carried out. The total number of patients receiving treatment in the hospital at that time, 42, were divided by a systematic method into 20families in an experimental group and 22 in a control group. The results from testing the hypotheses established in this study, to analyse the effects of family approach through reinforcement of functional communication, are as follows; The results of the test of the first hypothesis are shown in Table 1. “patients and their parents in an experimental group receiving group training in reinforcement of functional communication will show a greater degree of interaction than those of the control group” was supported. Significant differences included Main Effects p＜.001, Interactions p＜.001 and Explained p＜.001 in the interactions of patients, and mothers. Scores were higher for the experimental group after the treatment as well as higher than the control group.