• 제목/요약/키워드: graduate school

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A Study on the Establishment Plan for the SME Specialized Graduate School

  • Bae, Hoyoung
    • 한국벤처창업학회:학술대회논문집
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    • 한국벤처창업학회 2017년도 춘계학술대회
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    • pp.42-42
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    • 2017

  • There are lots of specialized graduate schools such as law school, medical school, business school. These specialized graduate schools has been designed to train the special experts practically from 1990s in Korea. For all that, there are no specialized graduate schools supported by the Small and Medium Business Administration(SMBA). So we will research the establishment plan of SME(Small and Medium Enterprise) specialized school for the development of SMEs. Recently, the SMBA supports the 2 types of graduate school such as the entrepreneurship graduate school and consulting graduate school. However, it is clear that these 2 types of schools are yet insufficient in terms of efficiency and redundancy. As the representative specialized graduate schools are law school and MOT(Management of Technology) in Korea, we do the comparative study with law school and MOT school. Through the comparative study, we can find some implication for SME specialized graduate school. As a result, the SME school has to need the training system such as the special master's and doctor's degree, over 3 year course work, daytime class, many practical professors, specialized programs with industry like the MOT school. In conclusion, we suggest that : First, the SME specialized graduate school has to be designed for potential SME consultants. Second, the entrepreneurship graduate school and the consulting graduate school can be integrated into the SME specialized school easily. Third, the SME specialized graduate school can have new educational models.

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Clinical Aspect of Dental Metals as Allergen Material in Japan

  • Hamano, H.;Ohyama, T.;Matsumura, M.;Hani, H.;Kitazaki, H.;Masuda, T.;Nokiba, K.;Hirohara, H.;Watanabe, K.;Mimura, H.
    • 대한치과보철학회:학술대회논문집
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    • 대한치과보철학회 2003년도 춘계학술대회 및 제1회 한일 공동 학술대회
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    • pp.76-76
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    • 2003

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The Enhancement of Immunological Activity by Mild Hypothermia

  • Hasegawa Takeo;Gu Yeunhwa;Miyata Katuyuki;Maeda Kayoko;Fukuyama Atsushi;Ando Satoshi;Amano Morikazu;Suzuki Tomoaki;Murabayashi Kousuke;Ida Kazushi;Yukiko Ohno;Kitaoka Hitomi;Kureki Michihiro
    • 한국방사성폐기물학회:학술대회논문집
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    • 한국방사성폐기물학회 2004년도 학술대회지
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    • pp.205-209
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    • 2004

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RUNX1-Survivin Axis Is a Novel Therapeutic Target for Malignant Rhabdoid Tumors

  • Masamitsu, Mikami;Tatsuya, Masuda;Takuya, Kanatani;Mina, Noura;Katsutsugu, Umeda;Hidefumi, Hiramatsu;Hirohito, Kubota;Tomoo, Daifu;Atsushi, Iwai;Etsuko Yamamoto, Hattori;Kana, Furuichi;Saho, Takasaki;Sunao, Tanaka;Yasuzumi, Matsui;Hidemasa, Matsuo;Masahiro, Hirata;Tatsuki R., Kataoka;Tatsutoshi, Nakahata;Yasumichi, Kuwahara;Tomoko, Iehara;Hajime, Hosoi;Yoichi, Imai;Junko, Takita;Hiroshi, Sugiyama;Souichi, Adachi;Yasuhiko, Kamikubo
    • Molecules and Cells
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    • 제45권12호
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    • pp.886-895
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    • 2022

  • Malignant rhabdoid tumor (MRT) is a highly aggressive pediatric malignancy with no effective therapy. Therefore, it is necessary to identify a target for the development of novel molecule-targeting therapeutic agents. In this study, we report the importance of the runt-related transcription factor 1 (RUNX1) and RUNX1-Baculoviral IAP (inhibitor of apoptosis) Repeat-Containing 5 (BIRC5/survivin) axis in the proliferation of MRT cells, as it can be used as an ideal target for anti-tumor strategies. The mechanism of this reaction can be explained by the interaction of RUNX1 with the RUNX1-binding DNA sequence located in the survivin promoter and its positive regulation. Specific knockdown of RUNX1 led to decreased expression of survivin, which subsequently suppressed the proliferation of MRT cells in vitro and in vivo. We also found that our novel RUNX inhibitor, Chb-M, which switches off RUNX1 using alkylating agent-conjugated pyrrole-imidazole polyamides designed to specifically bind to consensus RUNX-binding sequences (5'-TGTGGT-3'), inhibited survivin expression in vivo. Taken together, we identified a novel interaction between RUNX1 and survivin in MRT. Therefore the negative regulation of RUNX1 activity may be a novel strategy for MRT treatment.

  • https://doi.org/10.14348/molcells.2022.2031 인용 PDF KSCI

Studies on Root Restoration: Embedding Titanium and Cultured Periodontal Ligament Fibroblasts into the Intradentinal Cavities in Dogs.

  • Yamamoto, T.;Hirata, M.;Iwarnatsu, Y.;Tadatomo, Y.;Shimonishi, M.;Murakami, Y.;Nagaoka, S.;Higuchi, S.;Sato, H.;Kanehira, M.;Kindaichi, K.;Komatsu, M.
    • 대한치과보존학회:학술대회논문집
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    • 대한치과보존학회 2001년도 추계학술대회(제116회) 및 13회 Workshop 제3회 한ㆍ일 치과보존학회 공동학술대회 초록집
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    • pp.568.1-568
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    • 2001

  • The purpose of our study is new formation of periodontal ligament (PDL) around titanium implants. In this study, we investigated histologically whether cultured periodontal ligament fibroblasts (CPLFs) would form new PDL on titanium implants in beagle dogs. PDL fibroblasts were obtained from upper premolars of dogs and cultured in ${\alpha}-MEM$ supplemented with 10％ FBS. Some CPLFs were cultured on glass-beads-sandblasted titanium specimen. Artificial intradentinal cavities were prepared through alveolar bone to dentin of lower premolars.(omitted)

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