• 대한수의학회지
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• 제32권3호
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• pp.451-456
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• 1992

Seventeen antiserum identified by stormont method were used for investigation of appearance type of red blood cell in Cheju horse. Phenotype $A_1$, A', Z, $ZZ_2$, C, K, $P_1$, Q, R, S, $U_2$, X and $N_1$ were classified by Hemolytic reaction and agglutination in $E_2$, H, J and $T_1$, Hokkaido horse and Thoroughbred horse were compared with the type of red blood cell. The results obtained are as follows ; 1. According to the appearance frequency of red blood cell the phenotypes could be classified by 6 groups among horses tested; I group : C, $A_1$, $ZZ_2$, $E_2$, S, Q, II : $P_1$, $U_2$, X, III : A', R, IV : $T_1$, K, V : H, J, VI, $N_1$, Z. 2. In group I the type of C, $A_1$ and $ZZ_2$ showed the Similar frequency among horses but the type of $E_2$, S and Q was lower in Cheju horse than Hokkaido and Thoroughbred horse. 3. In group II there was no differences in the type of $P_1$ and among three species, but Thoroughbred horse was lowest as 11.2 percent than Cheju and Hokkaido horse. 4. The type of $U_2$ and X were highest in Cheju and Hokkaido horse but lowest in Thoroughbred horse. 5. The type of A' and R observed higher appearance frequency in Hoklcaido horse but in the Thoroughbred and Cheju horse appearance ratio were Strikingly lowered. 6. The type of $T_1$ and K was shown higher appearance frequency in Cheju and Thoroughbred horse similarily but lowered in Hokkaido horse. 7. In group V the type of H and J showed similarily as 30 to 40 percent in Cheju and Thoroughbred but no observation in Hokkaido horse. 8. The type of $N_1$ and Z which are group VI was great difference between Cheju and Hokkaido horse but higher in Hokkaido than Cheju horse while there was no observation in thoroughbred horse.

• 대한수의학회지
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• 제29권4호
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• pp.457-460
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• 1989

This work was carried out to get some informations about blood types and their researches, involved blood stock and genetic identification. Horses examined were total 55 heads of sire, mare and their progeny in Korean Horse Affairs Association. 1. Albumin phenotypes of 26 mare were examined. The appearance of phenotype AA, BB, AB, was 1, 18, 7 respectively. The gene frequency of albumin A was 0.17 and albumin B was 0.76. 2. The appearance of phenotype AA, BB, AB in 29 progeny was 1, 16, 12 respectively. The gene frequency of albumin A was 0.24 and albumin B was 0.76. The gene frequency of gene A was higher than their parents. 3. Identification of the relationship between parents and their progeny was also examined. 4 of type AB between AA & BB, 4 of type BB between BB & BB, 13 of type AB between BB & AB were borned. In third case, all of progeny was type AB. This results suggest positive relationship between them.

• 한국동물위생학회지
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• 제34권2호
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• pp.187-190
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• 2011

The Thoroughbred horse was an approximately 4-years-old castrated male with highly emaciation, nasal epistaxis and subsequently died. Gross necropsy revealed epistaxis and hyperemia on the lung, multiple hemorrhage in muscle, and liver was focally attached to the peritoneum with fibrin. According to polymerase chain reaction (PCR), Equine herpes virus type 1 and 4 (EHV type 1, 4) was detected in the lung and trachea. In bacterial culture from kidney, liver, spleen, muscle and blood, Streptococcus equi subsp. zooepidemicus was isolated. Based on the gross lesion and PCR, this horse was diagnosed as EHV type 1, 4 and S. zooepidemicus coinfection.

• 동의생리병리학회지
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• 제19권3호
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• pp.605-611
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• 2005

Chronic fatigue refers to the tiredness which disturbs one's daily activities and lasts more than six months without the sign of improvement by rest or sleep. Male chronic fatigue is included in internal injuries due to overstrain and exhaustion and closely related to river, spleen, stomach and kidney out of five Jang organs. Male chronic fatigue is based on the deficiency of Yang and aggravated by liquor, sex and emotional depression. Chronic fatigue has the following features in Hyungsang ; an inclination for lying: unwillingness to everything; drooping eyes and feeble voice; yellow pale complexion; withered ears; redness on the tip of nose; cheekbone, and lips; blood shot eyes; dryness and loss of hair. Male chronic fatigue usually attacks the persons of horse type and bird type because they are hyperactive compared with what they eat. The following medicines are commonly prescribed for the treatment of male chronic fatigue. Ssangwhatang, Sokunzungtang, and Yanghyulsamultang are commonly prescribed to horse type. Jaumkangwhatang, Chungsimyunzaum, Yookmijiwhangtang to bird type. Palmiwhan, Gozinumja. and Shinkihwan to fish type. Bozungikkitang, Galwhahaesungtang, Samchulgunbitang and Sipjundaebotang to turtle type.

• 동의생리병리학회지
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• 제24권2호
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• pp.187-196
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• 2010

We have come to a conclusion below after studying about the cause of limb hyperhidrosis through references, putting the result into practice clinically from Hyungsang remedy point of view, examining the effect of treatment. The cause of limb, palm and sole hyperhidrosis. The cause of limb hyperhidrosis is stomach heat(Yangmyung heat), weakness and coldness of stomach, moisture and heat of spleen and stomach, energy insufficiency of spleen and stomach, weakness of Yin of spleen and stomach, heat by weakness Yin meridian, unspread energy of liver, severe heat of heart, weakness of heart, shortage of blood, the functional disorder of kidney meridian and heart meridian(disposition of water ascension and fire descent), heat of blood(the functional disorder of heart) etc. The cause of palm hyperhidrosis is blood insufficiency of heart and liver or the functional disease of heart and stomach. The cause of sole hyperhidrosis is the functional disease of heart and kidney or the functional disease of kidney. Types classified by the cause of limb hyperhidrosis. The case of stomach heat, moisture and heat of spleen and stomach is found a lot in Yangmyeong and Fish Type. The case of weakness and coldness of stomach or insufficiency energy of spleen and stomach is found in Bangkwang and Ki Type, the shape of disorder of transfer and transformation of spleen and stomach. The case of severe heat of heart, the functional disorder of kidney meridian and heart meridian(disposition of water ascension and fire descent), heat of blood(the functional disorder of heart), heat by weakness of meridian of Yin is found a lot in Dam, Bird and Shin Type. Limb sweat caused by unspread energy of liver is found a lot in Horse Type. Palm sweat is found a lot in Bird or Yangmyeong Type. Sole sweat is found a lot in Fish or Taeum Type. Jeokbokryung-tang was good especially for type limb hyperhidrosis falling under the shape of the small intestines heat which conforms to the person having a short perpendicular furrow of the upper lip or lifted upper lip. Palmul-tang was good for type limb hyperhidrosis tending to having leaking liquid and humor because of the disorder of transfer of Jung, Ki, Shin, Hyul. Dossipyungwi-san and Hyangsapyungwi-san were good for type limb hyperhidrosis caused by stomach heat by food accumulation and Ki depression.

• 생명과학회지
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• 제32권1호
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• pp.29-35
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• 2022

본 연구는 여러 말 품종에서 Dopamine Receptor D4 (DRD4)의 유전적 다형성 및 Jeju crossbred에서의 기질특성과의 연관성을 분석하였다. DRD4 유전자의 다형성은 인간을 포함한 다양한 포유동물에서 기질과 연관된 후보 유전자이다. 말의 DRD4의 엑손 3번 영역에 있는 SNP G292A는 Thoroughbred에서 호기심과 경계와 관련이 있는 것으로 보고 되었다. 세 가지 말 품종에서 DRD4 유전자 내 존재하는 변이들의 다형성을 확인하기 위해 Sanger sequencing을 활용하였다. 제주마에서 각각의 빈도는 타 품종과 큰 차이를 보였다. 말의 품성 평가는 Jeju crossbred를 이용하여 수행하였으며, 기질 평가와 접촉 평가를 활용하여 각각 5개 항목과 2개 항목을 점수화 하였다. 품성 평가 결과 각 항목 간의 높은 상관관계를 확인하였다. 말의 DRD4 유전자 내 변이와 품성 평가 결과를 비교한 결과 대립유전자 A를 가지고 있을 때 기질 평가 5개 항목에서 모두 점수가 낮은 경향을 보이는 것을 확인하였으나 유의성은 없었다. Jeju crossbred의 G292A의 SNP과 혈액 내 도파민 수치를 비교한 결과 GA형이 GG형보다 약 2.87배 높은 결과를 확인하였다. 이번 연구를 통하여 DRD4 유전자 다형성과 말의 기질을 평가하기 위한 여러 평가 방법 및 신경전달물질과의 연관성을 확인할 수 있었다. 추가적인 연구를 통하여 품성 평가를 위한 유전자 마커로서 활용 가능할 것으로 사료된다.

• 대한한의학회지
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• 제34권1호
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• pp.52-68
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• 2013

Objectives: Hyungsang medicine (HM) is an inspection which emphasizes the relationships between pathological patterns and one's facial or bodily shape, color and movement. The purpose of this study was to review previously published study results of the HM. Methods: The authors reviewed a total of 51 HM-related studies published from 2000 to 2012 found on PubMed and various domestic Oriental medicine journals. Each study was classified into theoretical, diagnostic, or treatment-related category. Results: Theoretical studies were mostly based on the Nei-Ching and Dong-Eui-Bo-Gam texts, and dealt with differences in form between types such as masculine and feminine, the five organ image types, the four-type categorization of body essence, vital energy (Qi), mentality, and Blood, Gallbladder and Bladder, the four-type categorization of fish, bird, horse, and turtle types, and the six meridian types. Research on diagnosis has been performed on diagnostic characteristics of HM, correlation between HM and general coordinative manipulation (GCM), and Hyungsang medicine and ante-disease pattern (未病類型). Studies on treatments could largely be classified as treatments for specific diseases using certain acupuncture or herbal prescriptions based on HM. Treatments were mostly evaluated solely through subjective symptom improvement of patients. Conclusions: Our review results suggest that HM-related studies were focused on the constitutional characteristics and clinical utility of HM. To strengthen the theoretical basis of HM and its clinical utility, clinical trials including randomized, treatment-placebo and blind methods are needed.