• CELLMED
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• v.8 no.2
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• pp.6.1-6.7
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• 2018

Myristica fragrans Houtt is commonly known as "nutmeg", it produces two spices: mace and nutmeg. Mace and nutmeg are strongly aromatic in nature and known as jowzabuwa and javetri/bisbasah respectively in the Unani system of medicine. M. fragrans was used as early as 700 BCE by Indian, however, ancient Greeks and Romans were not aware of it. Later Arab traders introduce M. fragrans into Europe followed by Portuguese and Dutch merchants. Mace is very useful medicine in the Unani system of medicine because of its therapeutic uses in salasal al-bawl (urinary incontinence), amrad-i-qalb (cardiac diseases), amrad-i-dimagh (central nervous system), zo'fe bah (sexual debility), amrad al-rahim (uterine diseases), and su-i-hazim (indigestion). The most important constituents of mace essential oil are ${\alpha}-pinene$, sabinene, myrcene, limonene, 1,8-cineole, terpinen-4-ol, myristicin, ${\gamma}-terpinene$, and safrole. The seed and mace extract of nutmeg contain quite high tannins, flavonoids, and terpenoids. Mace has pharmacological functions such as antibacterial and antifungal, anti-inflammatory, analgesic, antidiarrhea, antioxidant, chemoprotective, neuropharmacologic, and antidiabetic properties. To explore the correlation between the traditional uses and the same proven by recent researches, a comprehensive review is highlighted in this paper. Further, pharmacological activities which are not reported in classical texts are also discussed.

• Annals of Laboratory Medicine
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• v.38 no.6
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• pp.538-544
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• 2018

Background: Serum copeptin has been demonstrated to be useful in early risk stratification and prognostication of patients with acute myocardial infarction (AMI). However, the prognostic value of copeptin after percutaneous coronary intervention (PCI) for clinical outcomes remains uncertain. We investigated the prognostic role of serum copeptin levels immediately after successful PCI as a prognostic marker for major adverse cardiac events (MACE; comprising death, repeat PCI, recurrent MI, or coronary artery bypass grafting) in patients with AMI. Methods: A retrospective study was performed in 149 patients with AMI who successfully received PCI. Serum copeptin levels were analyzed in blood samples collected immediately after PCI. The association between copeptin levels and MACE during the follow-up period was evaluated. Results: MACE occurred in 34 (22.8%) patients during a median follow-up of 30.1 months. MACE patients had higher copeptin levels than non-MACE patients did. Multiple logistic regression analysis showed that the increase in serum copeptin levels was associated with increased MACE incidence (odds ratio=1.6, P =0.005). Conclusions: A high level of serum copeptin measured immediately after PCI was associated with MACE in patients with AMI during long-term follow-up. Serum copeptin levels can serve as a prognostic marker in patients with AMI after successful PCI.

• Journal of Chest Surgery
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• v.55 no.6
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• pp.442-451
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• 2022

Background: This meta-analysis was conducted to evaluate the effect of fractional flow reserve (FFR) on clinical outcomes after coronary artery bypass grafting (CABG). Methods: Five online databases were searched for studies that (1) enrolled patients who underwent isolated CABG or CABG with aortic valve replacement and (2) demonstrated the effect of an FFR-guided strategy on major adverse cardiac events (MACE) after surgery based on a randomized controlled trial or adjusted analysis. MACE included cardiac death, acute myocardial infarction (MI), and repeated revascularization. The primary outcomes were all MACE outcomes and a composite of all-cause death and MI, and the secondary outcomes were the individual MACE outcomes. Publication bias was assessed using a funnel plot and the Egger test. Results: Six articles (3 randomized and 3 non-randomized studies: n=1,027) were selected. MACE data were extracted from 4 studies. The pooled analyses showed that the risk of MACE was not significantly different between patients who underwent FFR-guided CABG and those who underwent angiography-guided CABG (hazard ratio [HR], 0.80; 95% CI, 0.57-1.12). However, the risk of the composite of death or MI was significantly lower in patients undergoing FFR-guided CABG (HR, 0.62; 95% CI, 0.41-0.94). The individual MACE outcomes were not significantly different between FFR-guided and angiography-guided CABG. Conclusion: FFR-guided CABG might be beneficial in terms of the composite outcome of death or MI compared with angiography-guided CABG although data are limited.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.30B no.4
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• pp.44-55
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• 1993

In this paper, we proposed a new optical method for the efficient recognition of Korean characters. There are six filters in the proposed method which employed the concepts of amplitude-modulated phase-only filter(AMPOF) and spatial frequency modulation(SFM). Here, amplitude modulation is used to achieve improved correlation discrimination and SFM is to reduce the number of filters. We also used a simplified synthetic discriminant function(SDF) for distortion invariance of input image. In order to recognize the partial rotation invariant Korean characters, the proposed distortion invariant minimum average correlation energy (MACE) filter is synthesized SFM, partial rotation invariant filter (PRIF), AMPOF and MACE for partial rotation invariance in the frequency domain. The advantage of the proposed filters is to supress the sidelobes of cross correlation peak away from the autocorrelation peak and to produce sharp correlation peaks. We performed simulation and optical experiment for some of Korea characters using the proposed method. The results show that the proposed method has more improved discriminant ability and reduced processing time than the conventional methods.

• Proceedings of the Optical Society of Korea Conference
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• 2007.02a
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• pp.177-178
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• 2007

• Annual Conference on Human and Language Technology
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• 1989.10a
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• pp.148-153
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• 1989

본 논문에서는 광 상관기 (optical correlator) 에 의한 한글문자 분리 인식의 한 방법을 제안하였다. 효율적인 분리 인식을 위해서 병렬 나무 (tree) 구조로부터 입력 신호를 두 방향으로 병렬 처리하여 각 방향으로 자음과 모음을 따로 분리시켜 2단계 만에 인식한 뒤 이들을 위치에 따라 조합하여 문자 분리 인식하도록 하며, 아울러 이러한 병렬 나무구조의 각 단계에서 필터 합성시 MACE (minimum average correlation energy) 개념을 이용하여 광 상 관평면상에서 부엽의 문제를 줄이고, 실제 광 시스템에서 생길 수 있는 왜곡을 학습표본에 포함하여 광 상관기 시스템에 의한 실질적인 한글 문자의 왜곡에 무관한 분리인식을 하도록 하였다.

• 대학교육
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• s.8
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• pp.44-46
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• 1984

• Korean Journal of Optics and Photonics
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• v.14 no.4
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• pp.383-391
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• 2003

A new optical security system for the protection of personal identification information is proposed. Personal identification information consisting of a pure face image and an identification number is used for verification and authentication. Image encryption is performed by a fully phase image encryption technique with two random phase masks located in the input and the Fourier plane of 4-f correlator. The personal information, however, can be leaked out in the decryption process. To cope with this possibility, the encrypted image itself is used in the identification process. An encrypted personal identification number is discriminated and recognized by using the proposed MMACE_p (multiplexed MACE_p) filter, and then authenticity of the personal information is verified by correlation of the face image using the optical wavelet matched filter (OWMF). MMACE_p filter is a synthetic filter with four MACE_p (minimum average correlation energy_phase encrypted) filters multiplexed in one filter plane to recognize 10 different encrypted-numbers at a time. OWMF can improve discrimination capability and SNR (signal to noise ratio). Computer simulations confirmed that the proposed security technique can be applied to the protection of personal identification information.

• Korean Journal of Clinical Pharmacy
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• v.22 no.2
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• pp.113-122
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• 2012

ACC/AHA/SCAI Guideline recommends for administration dual antiplatelet therapy after drug-eluting stent (DES) to prevent restenosis and stent thrombosis in patients with percutaneous coronary intervention (PCI). Recently triple antiplatelet therapy including cilostazol is known to reduce restenosis and stent thrombosis significantly after DES implantation. However, there is lack of data providing the efficacy of triple antiplatelet therapy. The purpose of this study is to evaluate the clinical effects of the triple therapy after DES implantation compared with the dual therapy. This retrospective study collected data from medical charts of 251 patients who received DES implantation between Jul 2006 and Jun 2008. They received either dual antiplatelet therapy (N = 154 clopidogrel and aspirin; Dual group) or triple antiplatelet therapy (N = 97 cliostazol, clopidogrel and aspirin; Triple group). Major adverse cardiac event rates (MACE, included total death, myocardial infarction, target lesion revascularization) at 12 months, 24 months, stent thrombosis, rates of bleeding complications and adverse drug reactions were compared between these two groups. Compared with the dual group, the triple group had a similar incidence of the MACE rates at 24months (12.3% vs. 12.4%, p = 0.99). There is no difference in overall stent thrombosis between two groups (Dual group 2.6% vs. Triple group 4.1%, p = 0.5). Subgroup analysis showed that diabetic patients got more benefit in reducing MACE rates but, there is no statistical difference. Bleeding complications and adverse drug effects were not different significantly. As compared with dual antiplatelet therapy, triple antiplatelet therapy did not reduce the 12-months, 24-months MACE rates and stent thrombosis. Bleeding complications and adverse drug effects were not different.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.19 no.12
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• pp.2364-2375
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• 1994

For the efficient recognition of printed Korean characters, a multiplexed minimum average correlation energy(MMACE) filter is proposed. Proposed method solved the disadvantages of the tree structure algorithm which recognition system is very huge and recognition method is sophisticated. Using only one consonant MMACE filter and one vowel one, we recognized the full Korean character. Each MMACE filter is multiplexed by 4 K-tuple MACE filters which are synthesized by 24 consonants and vowels. Hence the proposed MMACE filter and the correlation distribution plane are divided by 4 subregion. We obtained the binary codes for the Korean character recognition from each correlation distribution subplane. And the obtained codes are compared with the truth table for consonants and vowels in computer. We can recognize the full Korean characters when substitute the corresponded consonant or vowel font of the consistent code to the correlation peak place in the output correlation plane. The computer simulation and optical experiment results show that the proposed compact Korean character recognition system using the MMACE filters has high discrimination capability.