• Journal of the Korean Society of Safety
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• v.38 no.2
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• pp.44-51
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• 2023

With the recent increase in gas energy use, risk management for explosion accidents has been emphasized. Protective walls can be used to reduce damage from explosions. The KOSHA GUIDE D-65-2018 suggests the minimum thickness and height of protective walls, minimum reinforcement diameter, and maximum spacing of reinforcements for the structural safety of the protective walls. However, no related evidence has been presented. In this study, the blast load carrying capacity of the protective wall was analyzed by the pressure-impulse diagrams while changing the yield strength of the reinforcement, concrete compressive strength, reinforcement ratio, protective wall height, and thickness, to check the adequacy of the KOSHA GUIDE. Results show that failure may occur even with design based on the criteria presented by KOSHA GUIDE. In order to achieve structural safety of protective walls, additional criteria for minimum reinforcement yield strength and maximum height of protective wall are suggested for inclusion in KOSHA GUIDE. Moreover, the existing value for minimum reinforcement ratio and the thickness of the protective wall should be increased.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.24 no.6
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• pp.691-697
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• 2011

In this study, the vessel collision protective structure and the vessel were modeled numerically and the quasi-static collision analysis was performed to evaluate the maximum protection capacity. In the modeling process of protective structure, the nonlinear behaviors of structure and the supporting conditions of ground including pull-out action were considered. In that of collision vessel, the bow of vessel was modeled precisely, because of the nonlinear behaviors were concentrated on it. For the efficient analysis, the mass scaling scheme was applied, also. To evaluate the differences and efficiency, the dynamic analyses were performed for the same model, additionally. Based on the obtained energy dissipation curves of the structure and the vessel, the moment that the collision force affected to the bridge substructures was determined and the maximum allowable collision velocity was evaluated. Because of the energy dissipation bound can be recognized clearly, this scheme can be used efficient in engineering work.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2011.04a
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• pp.731-734
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• 2011

본 연구에서는 강재로 구성된 선박충돌방호공의 최대방호능력을 산정하기 위하여 선박과 충돌방호공을 모델링하고 충돌거동을 해석하였다. 이러한 비선형충돌해석은 매우 큰 요소망과 고도의 비선형성을 려해야하기 때문에 이의 해석비용이 일반적인 해석에 비하여 매우 크므로 해석의 경제성을 확보하기 의사정적해석방법을 이용하여 해석을 수행하였다. 이 과정에서 효율적인 해석을 위한 수치 해석기법이 추가되었다. 해석결과 얻어진 선박과 방호공의 에너지소산곡선을 바탕으로 충돌선박이 교량하부구조에 도달하는 시점을 추정하고 이를 바탕으로 대상선박의 최대충돌속도를 산정하였다.

• Geomechanics and Engineering
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• v.28 no.3
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• pp.209-224
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• 2022

In this study, the numerical analysis model of π-beam explosion is established to compare and analyze the failure modes of the π-beam under the action of explosive loads, thus verifying the accuracy of the numerical model. Then, based on the numerical analysis of different protection forms of π beams under explosive loads, the peak pressure of π beam under different protection conditions, the law of structural energy consumption, the damage pattern of the π beam after protection, and the protection efficiency of different protective layers was studied. The testing results indicate that the pressure peak of π beam is relatively small under the combined protection of steel plate and aluminum foam, and the peak value of pressure decays quickly along the beam longitudinal. Besides, as the longitudinal distance increases, the pressure peak attenuates most heavily on the roof's explosion-facing surface. Meanwhile, the combined protective layer has a strong energy consumption capacity, the energy consumed accounts for 90% of the three parts of the π beam (concrete, steel, and protective layer). The damaged area of π beam is relatively small under the combined protection of steel plate and aluminum foam. We also calculate the protection efficiency of π beams under different protection conditions using the maximum spalling area of concrete. The results show that the protective efficiency of the combined protective layer is 45%, demonstrating a relatively good protective ability.

• Journal of the Korea Institute of Building Construction
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• v.14 no.6
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• pp.615-621
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• 2014

This study suggests the design and assembly drawing of the prefabricated precast concrete arch ammo magazines using the numerical analysis as well as the explosion verification test. The protective capacity of the proposed magazines is identified with the maximum support rotation angles measured by explosion verification tests according to the U.S. Unified Facility Criteria 3-340-02. Using numerical analysis, it is examined that oval-type members are better than the semi-circle ones in terms of protective capacity. Based on this numerical results, the design and assemble drawing for the prefabricated precast concrete arch ammo magazine are developed. It is identified that the structure constructed by invented design and assembly drawing has enough protective capacity against blast pressure caused by 133.75kg TNT explosion. The detonation point cannot be open due to the military security. In sum, it could be concluded that the ammo magazine proposed in this study has reliable protective capacity with enough redundancy. The redundancy means that there are more economic design approach with reducing the curved wall thickness.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.1
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• pp.190-198
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• 2007

Alzheimer's disease, a representative neurodegenerative disorder, is characterized by the presence of senile plaques and neurofibrillary tangles accompanied by neuronal damages. b-Amyloid peptide is considered to be responsible for the formation of senile plagues that accumulate in the brains of patients with Alzheimer's disease. There has been compelling evidence supporting that b-amyloid-induced cytotoxicity is mediated through generation of reactive oxygen species. In this study, we have investigated the possible protective effect of Rehmannia glutihosaagainst b-amyloid-induced oxidative ceil death in cultured human neuroblastoma SH-SY5Y cells. SH-SY5Y cells treated with b-amyloid underwent apoptotic death as determined by morphological features and positive in situterminal end-labeling (TUNEL staining). Rehmannia glutinosawater extract, wine, and vinegar pretreatments attenuated b-amyloid-induced cytotoxicity and apoptosis. Rehmannia glutinosa vinegar exhibited maximum protective effect by increasing the expression of anti-apoptotic protein, Bcl-2. in addition to oxidative stress, b-amyloid-treatment caused nitrosative stress via marked increase in the levels of nitric oxide, which was effectively blocked by Rehmannia glutinosa. To further explore the possible molecular mechanisms underlying the protective effect of Rehmannia glutinosa, we assessed the mRNA expression of cellular antioxidant enzymes. Treatment of Rehmannia glutinosa vinegar led to up-regulation of heme oxygemase-1 and catalase. These results suggest that Rehmannia glutinosa could modulate oxidative neuronal cell death caused by b-amyloid and may have preventive or therapeutic potential in the management of Alzheimer's disease. Particularly, Rehmannia glutinosa vinegar can augment cellular antioxidant capacity, there by exhibiting higher neuroprotective potential.

• Journal of the Korean Institute of Gas
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• v.17 no.6
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• pp.52-57
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• 2013

In this study, the strain energy density, stress and deformation behaviors have been analyzed as functions of a thickness and a force area of protective helmets with and without an extruder on the top of the shell structure using the finite element method. The strain energy density in which is related to the absorption capacity of an impact energy transfer is one of a key element of the helmet safety. The FEM analyzed results show that when the impulsive force of 4,540N is applied on the top surface of the helmets, the maximum stress is linearly reduced for an increased area of impact forces. But, the maximum strain energy density has been reduced for the increased force area. The reduced strain energy density may increase the impulsive forces transferred to the head and neck of helmet wearers, which may decrease the impact energy absorption safety of the helmets. In thus, it is safer design of the helmet in which has an extruded structure on the summit surface, but the modified helmet may decrease the impact energy absorption capacity.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.12
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• pp.1801-1807
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• 2014

Blue mussels (Mytilus edulis) are widely distributed among the world's oceans in various habitats. The purpose of this study was to investigate the effects of freeze-drying on the antioxidant and antigenotoxic activities of blue mussels collected in the Gyeongnam coast area of Korea. Raw (RM) and freeze-dried blue mussel flesh (FRM) were extracted with ethanol, methanol, and water. Antioxidant activities were evaluated on the basis of DPPH radical scavenging activity, oxygen radical absorbance capacity (ORAC), cellular antioxidant capacity (CAC), and antigenotoxic activity (comet assay). Except for the water extract, RM and FRM showed DPPH radical scavenging activities, which increased upon freeze-drying in MeOH extract. The highest ORAC value was observed in water extract of RM and MeOH extract of FRM. CAC was protected against AAPH-induced oxidative stress in HepG2 cells by both RM and FRM extracts. Freeze-drying lowered ORAC value of water extract, whereas it increased CAC activity, suggesting that antioxidant activities varied according to the generated radicals. All extracts from RM and FRM showed antigenotoxic activities by reducing $H_2O_2$-induced DNA damage in human leukocytes. Freeze-drying had no effect on antigenotoxicity of blue mussels. Taken together, these results indicate that blue mussels possess antioxidant and antigenotoxic properties, and freeze-drying might be a useful processing method for blue mussels to retain their maximum physiological potential as a functional food.

• Journal of the Korean Institute of Gas
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• v.22 no.4
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• pp.32-38
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• 2018

The purpose of this study is to assess quantitatively the amount of leaks and the extent of dispersion in case of a leak at a hydrogen fluoride tank container unloading station, and to suggest a safety improvement plan to prevent recurrence of similar accidents. In 2012, Company H leaks 8 tonnes of tank containers with a maximum storage capacity of 18 Ton, causing it to become a social issue. As a result of calculation using Gaussian plume model, the concentration was estimated to be more than 20ppm from the leak point to 1,321 m radius. The leakage of hydrogen fluoride from the company R in 2014 was estimated to be 11.02 kg, of which 2.9 kg was treated by the scrubber. As a result of calculation using Gaussian plum model, the damage range with a concentration of 20ppm or more from the leak source was estimated to be 69 m in radius. As a result of comparing the above two accidents, it was found that the leakage amount was about 987 times different and the damaged site was more than 19 times different. Therefore, it was concluded that it was necessary to control the wearing of the protective equipment, the enclosure of the unloading site, the installation of the scrubber, and the emergency training to avoid the accidental leakage of a hydrogen fluoride from the unloading site.

• Microbiology and Biotechnology Letters
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• v.46 no.4
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• pp.360-371
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• 2018

Extracts and fractions of Anemarrhena asphodeloides Bunge were prepared and their physiological activities and components were analyzed. Antimicrobial activities of the ethyl acetate and aglycone fractions were $78{\mu}g/ml$ and $31{\mu}g/ml$, respectively, for Staphylococcus aureus and $156{\mu}g/ml$ and $125{\mu}g/ml$, respectively, for Pseudomonas aeruginosa. 1,1-Diphenyl-2-picrylhydrazyl free radical scavenging activities ($FSC_{50}$) of 50% ethanol extract, ethyl acetate fraction, and aglycone fraction of A. asphodeloides extracts were $146.2{\mu}g/ml$, $23.19{\mu}g/ml$, and $71.06{\mu}g/ml$, respectively. The total antioxidant capacity ($OSC_{50}$) in an $Fe^{3+}$-EDTA/hydrogen peroxide ($H_2O_2$) system were $17.5{\mu}g/ml$, $1.5{\mu}g/ml$, and $1.4{\mu}g/ml$, respectively. The cytoprotective effect (${\tau}_{50}$) in $^1O_2$-induced erythrocyte hemolysis was 181 min with $4{\mu}g/ml$ of the aglycone fraction. The ${\tau}_{50}$ of the aglycone fraction was approximately 4-times higher than that of (+)-${\alpha}$-tocopherol (${\tau}_{50}$, 41 min). Analysis of $H_2O_2$-induced damage of HaCaT cells revealed that the maximum cell viabilities for the 50% ethanol extract, ethyl acetate fraction, and aglycone fraction were 86.23%, 86.59%, and 89.70%, respectively. The aglycone fraction increased cell viability up to 11.53% at $1{\mu}g/ml$ compared to the positive control treated with $H_2O_2$. Analysis of ultraviolet B radiation-induced HaCaT cell damage revealed up to 41.77% decreased intracellular reactive oxygen species in the $2{\mu}g/ml$ aglycone fraction compared with the positive control treated with ultraviolet B radiation. The findings suggest that the extracts and fractions of A. asphodeloides Bunge have potential applications in the field of cosmetics as natural preservatives and antioxidants.