• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.2
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• pp.365-372
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• 2004

The purpose of this study was to implement HACCP system to foodservice of W and D elementary schools with joint-lunch management system in Kyungsan area. Steamed rice with squid was selected and Control Action, Monitoring Procedure and Control measure were identified based on HACCP flowchart to produce safe and healthy food. It was suggested that frozen squid must be thawed under the cold running city water and kept temperature below 1$0^{\circ}C$ and receiving/thawing procedure has to be done within 30 min. Raw vegetables must be washed under three-tube wash stand and whole prepreparation procedures should be done in 20 minutes. Clean and sanitize all the equipment and utensils before and after handling squid. Knives and cutting boards for vegetable and squid should be classified. Sauce for steamed rice with squid should be heated about 21 minutes to reach the temperature of 94$^{\circ}C$ before serving and internal temperature of food must be kept above 84.4$^{\circ}C$ during serving. The ideal temperature of kitchen should be remained 15∼18$^{\circ}C$. The underground water has to be excluded to minimize the risk of contamination in the foodservice facility and the prepreparation place must be separated with cooking place. Also, Personal hygiene Practice should be check in each stage. Further, additional research needs to be conducted to determine models for HACCP implementation for different menu.

• Journal of the Korean Institute of Intelligent Systems
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• v.25 no.3
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• pp.279-286
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• 2015

The rapid increase of the current marine accidents is mainly due to the human execution errors. In an effort to address this, various kinds of researches such as construction of the digital vessels and vessel information monitoring systems have been conducted. But for safe navigation of vessels, it lack on systems study which can efficiently store, utilize and manage the mass data accepted by the vessel. In this paper, we propose a VWS(Virtual World System) that is based on the architecture of intelligent systems RVC(Reactive Layer-Virtual World-Considerative Layer) model of intelligent autonomous navigation system. VWS is responsible to store all the necessary information for safe navigation of the vessel and the information services to the sub-system of intelligent autonomous navigation system. VWS uses topology database to express the specific problem area, and utilizes a scheduling to reflect the characteristics of the real-time processing environment. Also, Virtual World defines API for the system to reflect the characteristics of the distributed processing environment. As a case study, the VWS is applied to a intelligent ship autonomous navigation system, and simulation is done to prove the effectiveness of the proposed system.

• Journal of Korean Medicine Rehabilitation
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• v.28 no.3
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• pp.13-25
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• 2018

Objectives We investigated anti-obesity effects of essential oils extracted from Cnidii Rhizoma (CR) in immature adipocytes to magnify it's clinical therapeutic usage. Methods Essential oil of CR was extracted with ethyl acetate or petroleum ether and through steam distillation, respectively. Oil red-O staining for monitoring its inhibition effect on adipogenesis and differentiation in murine 3T3-L1 adipocytes and 3-(4,5-methylthiazol-2-yl)-2,5-diphenyletetra zolium bromide (MTT) assay for cell safety were done. Also phospho-adenosine monophosphate (AMP)-activted protein kinase (P-AMPK), AMP-activated protein kinase, phospho-acetyl-CoA carboxylase (P-ACC), acetyl-CoA carboxylase, peroxisome proliferator-activated receptor-${\alpha}$ (PPAR-${\alpha}$), peroxisome proliferator-activated receptor-${\gamma}$ (PPAR-${\gamma}$) and CCAAT/enhancer binding protein ${\alpha}$ (C/EBP-${\alpha}$) expressions as obesity-related factors were measured by western blot analysis. Results Protein expressions of P-AMPK, P-ACC and PPAR-${\alpha}$ were increased in essential oils-treated adipocytes compared to those of control group, respectively. Furthermore, protein expressions of PPAR-${\gamma}$ and C/EBP-${\alpha}$ were decreased in essential oils-treated adipocytes compared to those of control group, respectively. Conclusions These results demonstrate that essential oils of CR inhibit adipogenesis and differentiation. Also they promote the oxidation of fatty acids in adipocytes. Thus, results suggest that essential oils of CR could be used as a valuable material for anti-obesity therapeutics via control of lipid metabolism.

• Particle and aerosol research
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• v.13 no.3
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• pp.105-110
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• 2017

Real-time measurements of fine particles from stack emission gases are necessary due to the needs of continuous environmental monitoring of PM10 and PM2.5. The porous tube dilutor using hot and cold dilutions was developed to measure fine particles without condensable particles from highly humid emission gases and compared to the commercialized ejector-type dilutor. Particle size distributions were measured at the emission gases from a diesel engine and a coal-fired boiler. The porous tube dilutor could successfully measure the accumulation mode particles including relatively large particles more than $3{\mu}m$ without nuclei particles, while the ejector dilutor detected some condensable particles and could not detect large particles. The porous tube dilutor could successfully remove the already condensed water droplet particles generated by a humidifier in a $30m^3$ chamber.

• Journal of the korean academy of Pediatric Dentistry
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• v.39 no.3
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• pp.257-266
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• 2012

The objective of this in vitro study was to monitor the amount of remineralization of decalcified enamel according to the number of fluoride varnish application using quantitative light-induced fluorescence-D and polarizing microscope. Artificial white lesion induced on the sound 72 teeth, $CavityShield^{TM}$ (Group I), $FluroDose^{TM}$ (Group II) and $Flor-Opal^{(R)}$ Varnish (Group III) were applied 1, 2 or 3 times every two weeks. The following results was obtained: 1. In group I, II and III, ${\Delta}L$ were increased. From regression analysis of ${\Delta}L$ by the number of application, the equation was y = 3.878x + 90.612 in group I, y = 3.133x + 37.168 in group II, and y = 3.509x + 82.322 in group III(p < 0.05). 2. In group I, II and III, ${\Delta}D$ were decreased. From regression analysis of ${\Delta}D$ by the number of application, the equation was y = -2.336x + 107.235 in group I, y = -2.158x + 101.620 in group II, and y = -1.940x + 94.806 in group III(p < 0.05). 3. The Pearson correlation value between the ${\Delta}L$ and ${\Delta}D$ was -0.673 in group I, -0.574 in group II, and -0.431 in group III(p < 0.05).

• Journal of Radiation Protection and Research
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• v.37 no.4
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• pp.219-225
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• 2012

This study makes differentiated regulations which can maximize the efficiency and convenience of radiation safety regulations by deriving evidence required to establish reasonable safety regulatory structure based on the determination of the levels of actual radiation safety regulations for radiation safety managers to perform radiation safety. We surveyed approximately 10% of radiation safety managers from domestic radiation-using organizations which was based on the Nuclear Safety Act and NUREG Vol. 1~21 of RS-G-1.9 (2005), NRC of IAEA, etc. The radiation safety managers showed the highest level of awareness on the requirements for exposure management ($3.32{\pm}0.910$), and the lowest level on the requirements for record keeping and storage of documents ($2.84{\pm}0.826$). Industrial organizations showed higher levels of awareness than medical organizations whose regulations should be more stringent on requirements of the status and management of radioactive sources, facilities, measurements, pollution control, measuring equipment, monitoring, education and training, and exposure management. This suggests that the actual regulations need to be re-evaluated because it is attributed to the regulations which are statistically significant difference of the levels of radiation safety regulations between industrial organizations and medical organizations. The process of developing regulatory requirements for each characteristic of domestic organizations needs to be done in future studies, as well as safety regulations to maximize convenience should be achieved if radiation safety regulations are conducted in consideration with the characteristics of each organization.

• Tuberculosis and Respiratory Diseases
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• v.68 no.1
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• pp.1-5
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• 2010

Background: To analyze the result of $^{18}F-FDG$ positron emission tomography (PET) in patients with a concomitant malignancy and tuberculoma in a tuberculosis (TB)-endemic area. Methods: Twelve patients with a concomitant malignancy and tuberculoma, who underwent whole-body $^{18}F-FDG$ PET, were evaluated retrospectively. The maximal standardized uptake values (SUVmax) of the malignancy and tuberculoma were compared. In 6 patients, $^{18}F-FDG$ PET was repeated during the anti-TB treatment and the changes in SUVmax were analyzed. Results: Of the 12 patients, 10 were male. The mean age was $67.2{\pm}7.9$ years. Tuberculomas were located in the lung (n=10) and lymph nodes (n=2), and tumors were located in the lung (n=6), colon (n=3), stomach (n=1), ovary (n=1) and liver (n=1). Although the mean SUVmax of malignant lesions was higher than that of tuberculomas ($5.2{\pm}3.2$ vs $3.5{\pm}2.0$), the difference was not significant. In 4 patients, the SUVmax was higher in the tuberculoma than the tumor. After anti-TB treatment in 6 patients, the mean SUVmax of the tuberculomas decreased significantly, from $3.5{\pm}2.0$ to $1.6{\pm}0.9$ (p=0.028). Conclusion: In patients with a concomitant malignancy and tuberculoma, SUVmax alone could not differentiate between them. However, $^{18}F-FDG$ PET may be useful in monitoring the response to anti-TB treatment.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.16 no.6 s.97
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• pp.549-555
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• 2005

This paper describes a microwave direction finding technology which is used for RF signal acquisition and monitoring systems. This paper suggests a direction finding method which use a combination of the amplitude-comparison technology and the phase-comparison technology. The amplitude-comparison technology uses the amplitude difference of the RF signals received from the array antennas of direction finding system and removes the ambiguity of wave incident bearing. The phase-comparison technology uses the phase difference of the RF signals received from the same nay antennas and makes a good direction finding accuracy. The suggested direction finding technology is designed to place 8 array antennas in a $45^{\circ}$ distance around the circle for $360^{\circ}$ azimuth angle. Also it is designed to use the phase difference of the received signals ken two nearby antennas to measure the signal incident direction accurately and to use the amplitude difference to remove the ambiguity of wave incident bearing. The simulation and measurement results are under $0.5^{\circ}$ bearing error in $2.0\~6.0$ GHz when SNR is 30 dB.

• Journal of Environmental Health Sciences
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• v.34 no.1
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• pp.86-94
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• 2008

Lake Shiwha, an artificial lake located near metropolitan Seoul, offers a unique water environment and has been suspected to have high levels of chemical and microbiological contaminations. Lake Shiwha was originally connected to the sea but currently has four major surface water inputs from agricultural, municipal, industrial areas and in addition an occasional inflow from the sea. The objectives of this study are to investigate the relative contribution of microbial contaminants from each of the inflowing surface waters and to identify appropriate microbial indicator organisms in this unique water environment. We measured the levels of microbial contaminations in the four inflowing surface waters. A number of microbial indicator organisms including total coliform (TC), fecal coliform (FC), E. coli, Enterococci, somatic and male-specific coliphages were analyzed. Bacterial indicator microorganisms were detected and quantified by the $Colilert^{(R)},\;Enterolert^{(R)}$ kit. Surface water (50 l) was sampled by $ViroCap^{TM}\;5"$ cartridge filters and analyzed by the single agar layer method for detecting coliphages. The concentrations of TC, FC, E. coli, and Enterococci were 1543 CFU/100 ml${\sim}1.99{\times}10^6$ CFU/100 ml, 0 CFU/100 ml${\sim}202$ CFU/100ml, 0 CFU/100 ml${\sim}1.80{\sim}10^5$ CFU/100ml, 74 CFU/100 ml${\sim}3408$ CFU/100 ml, respectively. The male-specific and somatic coliphages were detected in three different inflowing surface waters. Isolated E. coli and Enterococci strains were further analyzed by 16s rDNA amplification and subsequent phylogenetic analysis from Jungwang-chun, Ansan-chun, Banwol-chun and penstock of inflowing surface water. Our results indicated that the concentrations of different fecal indicator microorganisms might not be highly correlated with each other. Multiple microbial indicator organisms should be used for monitoring microbial contamination and microbial source tracking methods.

• Journal of Environmental Health Sciences
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• v.36 no.1
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• pp.52-60
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• 2010

High performance liquid chromatography (HPLC) and liquid chromatography mass spectrometry (LC/MS) have been widely used to quantify aflatoxins in food, but these methods are expensive, time-consuming, unsuitable for analysis of the routine screening of large sample numbers and require derivatization and high level techniques to perform. The objective of this study is to detect aflatoxins in a large number of foods by a high efficient analytical system of combined enzyme linked immunosorbent assay (ELISA) for screening and LC/MS/MS for confirmation. The samples spiked individually with aflatoxin $B_1$ (0.5 and 1.0 ng/g) and total aflatoxins (10 ng/g) were analyzed by ELISA and LC/MS/ MS, and the recoveries for ELISA and LC/MS/MS were 71.8~119.2% and 70.8~135.3%, respectively. A total of 378 samples (grains, nuts, soybean and fermented soybean foods, pepper and fermented pepper foods) were purchased from the six major cities in Korea and analyzed by ELISA-LC/MS/MS system. Twenty two (5.8%; peanut: 11, pistachio: 2, walnut: 6, almond: 1, pepper powder: 1, pepper paste: 1) out of 378 samples were screened as aflatoxin B1 positive by ELISA, but, 4 (1.1%; peanut: 2, pistachio:1, pepper powder: 1) out of the 22 samples screened were confirmed as aflatoxins positive at levels of 1.02~52.79 ng/g by LC/MS/MS. ELISA-LC/MS/MS system provides a more rapid, accurate and cost-effective method for the detection of aflatoxins in large number of samples.