• Title/Summary/Keyword: muscle injury

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Effects of Electroacupuncture and Electrical Stimulation on VEGF Expression After Muscle Crush Injury in Rats (전침 자극과 전기 자극의 적용이 근육압좌손상이 유발된 흰쥐의 골격근 내 혈관내피성장인자 발현에 미치는 영향)

  • Kim, Min-Hee;Lee, Hyun-Min;Park, Eun-Se;Nam, Ki-Won;Kim, Jin-Sang
    • Physical Therapy Korea
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    • v.13 no.2
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    • pp.9-15
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    • 2006
  • Skeletal muscle injury occurs frequently in sports medicine and is the most general form of injury followed by physical impact. There are growth factors which conduct proliferation, differentiation, and synthesis of myogenic prodromal cells and regulate vascular generation for the continued survival of myocytes. The purpose of the present study was to confirm the effects of electroacupuncture (EA) and electrical stimulation (ES) on muscle recovery processes according to vascular endothelial growth factor (VEGF) expression. Eighteen Sprague-Dawley rats were separated into 2 experimental groups and a controlled group. All animals had suffered from crush damage in the extensor digitorum longus for 30 seconds and were killed 1, 3, and 7 days after injury. 30 Hz and 1 mA impulsion for 15 minutes was applied to the EA experimental groups Zusanli (ST36) and Taichong (LR3) using electroacupuncture and the same stimulation was applied to the ES group using an electrical node. Hematoxyline-Eosin staining and VEGF immunohistochemistry were used to ascertain the resulting muscle recovery. There were few morphological differences between the EA and ES groups, and both groups were observed to have tendencies to decrease atrophy as time passed. In the controlled group, gradually diminishing atrophy could be observed, but their forms were mostly disheveled. There were few differences in VEGF expression between the EA and ES groups, and tendencies to have an increased quantity of VEGF with the lapse of time were observed in both groups. In the controlled group, a little VEGF expression could be observed merely 7 days after injury. In conclusion, EA and ES contributed to muscle recovery processes and could be used for the treatment of muscle injury.

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Factors Influencing Satellite Cell Activity during Skeletal Muscle Development in Avian and Mammalian Species

  • Nierobisz, Lidia S;Mozdziak, Paul E
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.3
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    • pp.456-464
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    • 2008
  • Avian and mammalian skeletal muscles exhibit a remarkable ability to adjust to physiological stressors induced by growth, exercise, injury and disease. The process of muscle recovery following injury and myonuclear accretion during growth is attributed to a small population of satellite cells located beneath the basal lamina of the myofiber. Several metabolic factors contribute to the activation of satellite cells in response to stress mediated by illness, injury or aging. This review will describe the regenerative properties of satellite cells, the processes of satellite cell activation and highlight the potential role of satellite cells in skeletal muscle growth, tissue engineering and meat production.

The Effects of Trapezius and Serratus Anterior Strengthening Exercise on Pain and Muscle Activation in Spinal Cord Injury Patients with Functional Shoulder Impingement Syndrome (승모근과 전거근 강화운동이 기능적 어깨충돌증후군을 가진 척수손상 환자의 통증과 근 활성도에 미치는 영향)

  • Kim, Sang-Chul;Lee, Young-Min;Shin, Kyu-Hyun
    • PNF and Movement
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    • v.16 no.1
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    • pp.33-42
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    • 2018
  • Purpose: The aim of this study was to investigate the effects of trapezius and serratus anterior strengthening exercise on the shoulder pain and muscle activation of patients with spinal cord injury and functional shoulder impingement syndrome. Methods: The study consisted of 10 patients with spinal cord injury who were hospitalized in Rehabilitation Hospital U, Uijeongbu, South Korea. The exercise was implemented three times a week for 10 weeks. In each session, the subjects performed one of a total of five types of exercise at mid-level intensity. The shoulder pain and disability index (SPADI) was used to evaluate the patients before and after the intervention. The muscle activation of the upper trapezius, middle trapezius, lower trapezius, and anterior serratus muscle was assessed by surface electromyography (EMG) at the beginning of the experiment and 10 weeks later. Wilcoxon's singed-rank test was conducted to determine differences in the pain index and muscle activation before and after the exercise. The level of statistical significance was set at ${\alpha}=0.05$. Results: SPADI scores significantly decreased after the exercise (p<0.05). In comparisons of muscle activation, there was a significant improvement in the upper trapezius at $60^{\circ}$ shoulder joint flexion (p<0.05). There was no significant improvement at $90^{\circ}$ shoulder joint flexion. The middle trapezius showed a significant improvement at $120^{\circ}$ shoulder joint flexion (p<0.05). Conclusion: Trapezius and serratus anterior strengthening exercise reduced pain in spinal cord injury patients with functional shoulder impingement syndrome. The decreased muscle activation of upper trapezius and increased muscle activation of the anterior serratus muscle at $60^{\circ}$ shoulder joint flexion point to positive effects of the exercise on supraduction of the scapula.

Development of Electrical Stimulator for Restoration of Locomotion in Paraplegic Patients (하반신마비 환자에서 보행기능의 복원을 위한 전기자극법의 개발)

  • 박병림;김민선
    • Journal of Biomedical Engineering Research
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    • v.15 no.4
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    • pp.429-438
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    • 1994
  • An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate eleclromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocnemius m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher'stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical slimulator restored partially gait function in paraplegic patients.

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The clinical study on 37 cases of whiplash injury patients which caused by traffic accident (교통사고(交通事故)로 인한 편타성(鞭打性) 손상(損傷) 환자(患者) 37례(例)에 대한 임상연구(臨床硏究))

  • Kang, Jae-Hui;Jang, Suk-Geun;Lee, Hyun;Lee, Byung-Ryul
    • Journal of Acupuncture Research
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    • v.19 no.3
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    • pp.180-191
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    • 2002
  • Objective : This study was performed to evaluate the effect of oriental medical treatment in whiplash injury patients which caused by traffic accident. Methods : The clinical study was carried out 37 cases of whiplash injury patients which had been admitted in Daejon university Cheon-an oriental hospital from June, 2001 to December, 2001. Results : l. In the distribution of sex distinction was female much more than male in the ratio of 3:2 and thirties was most in age distribution. 2. In situation of traffic accident, The most case was rear-ending(70.27%). 3. Except cervical pain or it's reffered pain, there were whole body symptoms as fallow, insomnia in 11cases(29.73%), night pain in 10 cases(27.03%), general body pain in 8cases(21.62), dizziness in 6cases(16.22%). 4. According to Meridian Muscle theory, a injured parts of patient were devided as follows. There were 22cases(59.46%) which have injury in Bladder, Small Intestine Meridian Muscle, 10cases(27.03%) in Gallblader, Triple Energizer Meridian Muscle, 5cases(13.51%) in Stomach, Large Intestine Meridian Muscle. 5. There were 6cases(16.22%) of the grade of complete recovery, 10cases(27.03%) of the grade of excellent, 12cases(32.43%) of the grade of improvement, 6cases(16.22%) of the grade of disimprovement and 3cases(8.11%) of the grade of poor. So 28cases(75.68%) were efficacious. 6. Generally Herb-meds that have efficacy of Geo-Eohyeol were most used(27cases, 72.97%) in early stage. Secondly Herb-med that have efficacy of Yiqi-sunqi were used(20case, 54,05%) in middle stage and Herb-med of Bo-Qiheol were used(l0cases, 27.03%) in latter term. The most used Herb-med was Hoisu-san, Oyaksungi-san(22cases, 54.96%). 7. In l5cases which have Aqua-Acupuncture treatment, There were 3cases of Complete recovery, 5cases of Excellent, 4cases of Improvement, 2cases of Disimprovement, 1cases of Poor. 8cases(53.33%) were above Excellent grade, so it is more efficatious Than simple treatment without Aqua-Acupuncture(36.37%). 8. The improvement of Bladder, Small Intestine Meridian Muscle was 77.27%, Gallblader, Triple Energizer Meridian Muscle was 70% and Stomach, Large Intestine Meridian Muscle was 80%. Additional Aqua-Acupuncture treatment improved to be effective in Bladder, Small Intestine Meridian Muscle(77.78%), in Gallblader, Triple Energizer Meridian Muscle(75%), in Stomach, Large Intestine Meridian Muscle(100%). Conclusions : In this study, Oriental treatment especially Aqua-Acupuncture was effective in whiplash injury patients which caused by traffic accident.

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Circulating Plasma and Exosomal microRNAs as Indicators of Drug-Induced Organ Injury in Rodent Models

  • Cho, Young-Eun;Kim, Sang-Hyun;Lee, Byung-Heon;Baek, Moon-Chang
    • Biomolecules & Therapeutics
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    • v.25 no.4
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    • pp.367-373
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    • 2017
  • This study was performed to evaluate whether microRNAs (miRNAs) in circulating exosomes may serve as biomarkers of drug-induced liver, kidney, or muscle-injury. Quantitative PCR analyses were performed to measure the amounts of liver-specific miRNAs (miR-122, miR-192, and miR-155), kidney-specific miR-146a, or muscle-specific miR-206 in plasma and exosomes from mice treated with liver, kidney or muscle toxicants. The levels of liver-specific miRNAs in circulating plasma and exosomes were elevated in acetaminophen-induced liver injury and returned to basal levels by treatment with antioxidant N-acetyl-cysteine. Circulating miR-146a and miR-206 were increased in cisplatin-induced nephrotoxicity and bupivacaine-induced myotoxicity, respectively. Taken together, these results indicate that circulating plasma and exosomal miRNAs can be used as potential biomarkers specific for drug-induced liver, kidney or muscle injury.

The Effect of Motor Imagery on Onset Time of Leg Muscle and Ankle Injury Score of Patients with Functional Ankle Instability (상상운동이 기능적 발목관절 불안정성 환자의 하퇴 근육 근수축 개시시간 및 발목손상 척도에 미치는 영향)

  • Lim, Hyoung-Won
    • The Journal of Korean Physical Therapy
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    • v.24 no.1
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    • pp.7-14
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    • 2012
  • Purpose: The purpose of this study was to investigate the effect of motor imagery on the onset time of the leg muscle and ankle injury score of patients with functional ankle instability. Methods: The study included 16 patients with ankle instability after their ankle sprains. Motor imagery was performed 3 times a week for 4 weeks. The onset time of leg muscles was measured by using the surface EMG in one leg standing position on tibialis anterior, peroneous longus and medial, lateral gastrocnemius. The pre- and post-intervention was measured by using the ankle injury score. Data was analyzed by a paired t-test. Results: The onset time was reduced but there was no significant difference (p>0.05). The order of muscle recruitment was changed. Anke injury score increased significantly after motor imagery (p<0.05). Conclusion: The results suggest that motor imagery was effective by showing delayed onset time of peroneal muscle in patients with functional ankle instability. In future studies, various conditions and disorders should all be considered for the effective analysis of motor imagery.

Effect of Muscle Fatigue on the Proprioception by the Taekwondo Training Type

  • Seo, Byoung-Do;Kim, Hui-Jae;Ju, Joung-Youl
    • Journal of the Korean Society of Physical Medicine
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    • v.15 no.3
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    • pp.1-9
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    • 2020
  • PURPOSE: This study examined the effects of muscle fatigue on proprioception in the type of taekwondo training, causing injury to taekwondo athletes. METHODS: The subjects were divided into Taekwondo Kyorugi athletes (n = 14) and Taekwondo Poomsae athletes (n = 14). After inducing muscle fatigue to the subjects, the joint position sense (JPS) and the force reproduction sense (FRS) were measured before and immediately after the induction of muscle fatigue. RESULTS: Studies have shown no significant impact on the JPS and FRS caused by muscle fatigue induced by Poomsae and Kyorugi (p > .05). The JPS, however, showed a significant difference before and after Kyorugi (p < .05). The FRS showed significant differences before and after Poomsae (p < .05). Through this study, the injuries to taekwondo athletes appear to be influenced by the joint position and force reproduction. Moreover, the injury appears to affect the joint position sense in Kyorugi athletes and the force reproduction sense in Poomsae athletes. CONCLUSION: The results will contribute to injury prevention and athlete protection. In addition, the information can be used as basic data for the development of sports injuries prevention and rehabilitation programs for Taekwondo athletes. Research is needed on the customized management of sports methods and self-care to prevent sports damage, considering the athletic characteristics of the taekwondo athletes in the future.

The surgical treatment of acute traumatic rupture of proximal hamstring muscle -A case report- (급성 외상성 근위 슬괵근 파열에서의 수술적 치료 -증례보고-)

  • Jang, Young-Soo;Rha, Jong-Deuk;Jung, Jae-Wook;Yang, Jin-Phil
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.9 no.2
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    • pp.125-129
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    • 2010
  • The hamstring muscle injury is a quite common sports injury which has a wide spectrum of treatment option that simple muscle strain can be treated conservatively otherwise total rupture of muscle or musculotendinous junction must be treated surgically. Among them, rupture of proximal hamstring muscle near at its origin site is quite uncommon and it should be treated surgically because it could cause several complications if not treated appropriately. In this case report, the authors report successful surgical treatment of acute rupture of proximal hamstring muscle and also would like to review the clinical presentation of this type of injury.

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Patients Treated with Acupuncture on Splenius Muscle and Combined Korean Medicine for Acute Dizziness Caused by Whiplash Injury: Three Case Reports (현훈을 동반한 편타성 손상 환자에 대한 판상근 아시혈 침치료 중심의 한방복합치료 치험 3례)

  • Ryu, Gwang-hyun;Ju, Ah-ra;Park, Mi-so;Choo, Won-jung;Choi, Yo-sup;Moon, Young-joo;Choi, Hyo-jung
    • The Journal of Internal Korean Medicine
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    • v.41 no.6
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    • pp.1210-1222
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    • 2020
  • Objective: The purpose of this study was to report the effect of acupuncture on the splenius muscle and the effect of combined Korean medicine treatment on acute dizziness in patients due to whiplash injury. Methods: Three patients with acute dizziness were treated with acupuncture of the splenius muscle and combined Korean medicine. A numeric rating scale (NRS) and the Korean dizziness handicap inventory (K-DHI) were checked every day from admission to discharge to confirm symptom improvements. Results: In the acute stage of dizziness caused by whiplash injury, acupuncture of the splenius muscle and combined Korean medicine improved the NRS and K-DHI scores. Conclusions: For patients with acute dizziness caused by whiplash injury, a combination of acupuncture on the splenius muscle and Korean medicine treatment may be a solution.