• Title/Summary/Keyword: obesity

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Low-Dose Off-Label Use of Phentermine/Topiramate in the Individual with Morbid Obesity and Postoperative Hypothyroidism (수술 후 갑상선기능저하가 동반된 고도비만환자의 펜터민염산염/토피라메이트의 저용량 오프라벨 사용)

  • Park, Jung Ha
    • Archives of Obesity and Metabolism
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    • v.1 no.1
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    • pp.43-45
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    • 2022
  • Intensive lifestyle modifications and anti-obesity medications are essential for obesity treatment. Antiobesity medications should be selected according to the patient's comorbidities, symptoms, and preferences. This case report describes the treatment of a morbidly obese patient with a history of depression, who complained of tingling and numbness after total thyroidectomy for papillary thyroid cancer. Very low-dose controlled-release phentermine/topiramate was prescribed and intensive lifestyle modifications were encouraged. As a result, the patient effectively lost weight and reached a near-normal weight without adverse drug effects. This implies that even an off-label anti-obesity medication low dose may be better for some patients, and the most important factor in obesity treatment is patient-tailored treatment.

Obesity Paradox-Bias or Fact? (비만 역설-편향 혹은 실제)

  • Kim, Bom Taeck
    • Archives of Obesity and Metabolism
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    • v.1 no.1
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    • pp.33-38
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    • 2022
  • Although it has been confirmed that excessive body fat increases health risks and all-cause mortality, several epidemiological studies have reported that overweight or obesity in patients with chronic diseases and in older adults is advantageous with respect to mortality. Several mechanisms have been proposed to explain the biological basis of this obesity paradox. The marked heterogeneity of findings observed across studies and the possibility of systematic errors in these studies have cast doubt on the actual existence of the obesity paradox. However, the obesity paradox questioned the validity of body mass index as the best indicator for obesity in terms of predicting its comorbidities and urges clinicians to focus more on changes in body composition and related metabolic derangements, rather than body weight per se.

A Case of Morbid Obese Patient with Comorbidities: Why a Lifestyle Modification is Important (동반 질환을 가진 고도 비만 환자의 증례: 생활습관 교정이 왜 중요한가?)

  • Eunjin Shin;Seon Yeong Lee
    • Archives of Obesity and Metabolism
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    • v.2 no.2
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    • pp.64-70
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    • 2023
  • Obesity is a complex multifactorial disease that is associated with various complications, including cardiovascular diseases. The prevalence of obesity among young adult males has increased, and this has increased the prevalence of several comorbidities. This trend was closely linked to lifestyle factors, including heavy drinking, smoking cigarettes, and an imbalanced diet. This emphasized the necessity of lifestyle improvements for effective obesity management. In this case, the comprehensive lifestyle changes and adjuvant medication resulted in weight loss and improvement in several comorbid conditions in a young adult male. The case highlighted the importance of a comprehensive approach to managing obesity. Furthermore, it emphasized the importance of a healthy lifestyle in addressing obesity and its complications.

DITI of the Obesity Patients Compared with Non Obesity Group (DITI로 측정한 비만 환자의 체표 온도 분포 양상)

  • Ha, Jee-Yeun;Joe, Jung-Hoon;Jang, Jun-Bock;Lee, Kyung-Sub
    • Journal of Oriental Medical Thermology
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    • v.2 no.1
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    • pp.43-48
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    • 2003
  • Obesity is excess body weight, defined as a body mass index (BMI) over 30 kg/m2. or 20% over than relative body weight (RBW). We can consider the surface temperature of obesity patients is related with fat distribution and differs from that of non obesity people. The temperature is measured by using Digital Infrared Thermal Imaging(DITI). DITI was taken on 109 people without any specific disease. Among those subjects, obesity group is 77 and non obesity is 32. We measured the surface temperature by describing regular square on the upper arm, lower arm, palm, upper leg, lower leg, foot, upper abdomen and lower abdomen. The temperature of upper leg, upper abdomen and lower abdomen was low (p<0.001) and that of palm and foot was high (p<0.05) in obesity group. The temperature and the difference of lower arm to palm and lower leg to foot correlated with RBW. These results suggest the surface temperature in obesity group differ remarkably from that in non obesity group.

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The Change of Weight Loss of Oriental Obesity Treatment (한방비만프로그램의 체중감량 경과 관찰)

  • Lee, Yoon-Jae;Ryu, Eun-Kyung
    • Journal of Korean Medicine for Obesity Research
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    • v.9 no.1
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    • pp.53-58
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    • 2009
  • Objectives The purpose of this study was to investigate the clinical effect of oriental medical therapy on obesity and the progress of weight loss through an oriental obesity program. Methods The subjects were treated from January 2008 to February 2009 in J Korean Medical Hospital. Herbal medical Hospital. Herbal medicine, electrolipolysis, auricular acupuncture were performed during the treatment period. We checked the change of weight every treatment time and measured the body composition by bioelectrical impedance analysis(BIA) every 2 weeks. Results The progress of weight loss was steady in the first 4 weeks except for the sixth weight check. After 4 weeks treatment, the weight loss was 3.52${\pm}$1.98Kg and 4.83${\pm}$2.68%. Total fat mass measured by BIA significantly decreased 2.58${\pm}$1.30Kg after 4 weeks. Age and the weight loss were significantly negative correlated. Conclusions Oriental obesity treatment could be effective on obesity, but further studies would be needed for the foundation of a clinical guideline reflecting various factors.

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An Update on Mental Health Problems and Cognitive Behavioral Therapy in Pediatric Obesity

  • Kang, Na Ri;Kwack, Young Sook
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.23 no.1
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    • pp.15-25
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    • 2020
  • Prevalence of pediatric obesity has increased worldwide in the last 20 years. Obese children suffer not only physical complications but also mental health problems such as depression, attention deficit hyperactivity disorder (ADHD), and eating disorders, as well as psychosocial impairments, such as school adjustment problems, bullying, and low self-esteem. Recently, there have been some studies on the association of mental health problems and pediatric obesity. In the treatment of pediatric obesity, many previous studies suggest multidisciplinary treatment. However, cognitive behavioral therapy (CBT) has attracted attention because obese children are accompanied by body image distortion, emotion dysregulation, and difficulties in stimulus control. This review is a narrative summary of the recent studies on mental health problems and CBT in pediatric obesity. The relationship between depression/anxiety and pediatric obesity is still inconsistent but recent studies have revealed a bidirectional relation between depression and obesity. Additionally, some studies suggest that obese children may have eating disorder symptoms, like loss of control eating, and require therapeutic intervention for pediatric obesity treatment. Furthermore, impulsivity and inattention of ADHD symptom is thought to increase the risk of obesity. It has also been suggested that CBT can be very effective for mental health problems such as depression, impulsivity, and body image distortion, that may coexist with pediatric obesity, and use of multimedia and application can be useful in CBT.

Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice

  • Kang, Kwang-Soon
    • Journal of the Korea Society of Computer and Information
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    • v.21 no.7
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    • pp.61-66
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    • 2016
  • The frequency of obesity has risen dramatically in recent years but only few safe and effective drugs are currently available. In addition, obesity can induce type 2 diabetes (T2DM), hyperlipidemia and fatty liver disease. Recently, protective effect of purslane extract (PE) on obesity has been reported, but little is known about the role and mechanism of PE in obesity. This study aimed to evaluate the effect of PE on obesity and diabetes in obese mice. In addition, the effect of PE was compared with anti-obesity and diabetes drugs. High-fat diet (HFD)-induced obese mice were treated for 8 weeks with drugs as follows: PE, orlistat, metformin, voglibose or pioglitazone. While PE mixed with normal diet did not have any effects on BW in non-obese mice, PE mixed with HFD significantly reduced BW gain, insulin resistance, and glucose intolerance, without affecting food intake and appetite in obese mice. The effect was comparable to the effects of anti-obesity and diabetes drugs. Furthermore, PE significantly increased the activity of hepatocellular anti-oxidant enzymes, leading to protection of liver from oxidative stress in obese mice. These results suggest that PE treatment may be a useful tool for preventing obesity and complication of obesity.

A Study on the Effects of Obesity Control Program for Obese Students in Primary School (초등학교 비만아동을 위한 비만관리 프로그램의 효과)

  • Kim, Mee-Kyung;Hyun, Hye-Jin
    • Journal of Korean Biological Nursing Science
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    • v.10 no.2
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    • pp.141-146
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    • 2008
  • Purpose: The objective of this study was to study the effect of the obesity control program to the extent of the overweight children's knowledge about obesity, physical exercise, dietary habits and the extent of obesity. Methods: A total of 61 elementary school children between the age of 9-12 were chosen for this study: 31 overweight children whose extent of obesity exceeded over 20% when measured using Broca index and other 30 overweight children of the same category for the comparison as a control group. The obesity control program made up of regular physical exercise for five days per week and a weekly diet education and consultation was implemented for the period of 8 weeks. Results: The knowledge about obesity, regular physical exercise, and diet habits were significantly improved after implementing the obesity control program, as compared to the control group. But the extent of obesity was not significantly decreased. Conclusion: These results suggest that the studies are needed to define factors of effective program and develop the effective program for decreasing the extent of obesity.

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Characterizing of Four Obesity Types in Obese Women Based on the Questionnaire of Diseases and Physical Tests (여성 비만의 유발유형별 일반 증상과 검사 특성 연구)

  • 진승희;최경미;박영배
    • The Journal of Korean Medicine
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    • v.25 no.1
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    • pp.172-187
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    • 2004
  • Objectives : To characterize four types of obesity and to effectively improve the treatment of obesity through Oriental medicine Methods : At 00 Oriental Medical Center, 203 female subjects who intented to lose weight were requested to complete a questionnaire. These participants were also given physical tests. The Questionnaire consisted of questions both about general life style and obesity in oriental medicine framework. The physical tests were blood tests, a body composition via Inbody 2.0, and physical strength tests. One-way analysis of variance was done to compare the means of items and physical tests between four types of obesity. Duncan was used by post hoc test. Results : 1. Significant differences between obesity type III and obesity type IV in ever tried to lose weight, childhood obesity and excercise times were observed in the questionnaire of general life style(p<0.05). 2. Ducan test showed significant differences between four obesity types in diseases (p<0.05). 3. Significant differences between four obesity types in height, % body fat muscular endurance, soft lean mass, fat mass, Trigliceride, Total cholesterol and ${\gamma}-GTP$ were observed (p<0.05). Conclusions : Further clinical research is necessary in the four types of obesity explored. The diagnosis and treatment based on these types should be further studied.

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The Effect of Zymolysis-Dietotherapy with Herbal Formula on the Obesity (발효식이요법과 한약 약물치료를 병행한 한방비만치료의 효과)

  • Kim, Dae-Bok;Chang, Sun-Kyu;Cho, Chung-Sik;Kim, Chul-Jung
    • Journal of Haehwa Medicine
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    • v.17 no.1
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    • pp.75-82
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    • 2008
  • Objective : The purposes of this study are to evaluate the effect of zymolysis-dietotherapy with herbal formula on the obesity and to improve the oriental medical methods of treatment in obesity patients. Methods : Forty one patients were classified into four groups(Normal, Overweight, 1st Obesity, 2nd Obesity) by Body Mass Index(BMI). Weight, body fat rate, BMI and obesity index were compared in each group by paired t-test. Results : The weight, BMI and obesity index were decreased significantly in all groups. Except normal group, the body fat were decreased significantly. The body fat rate were decreased significantly in 1st obesity and 2nd obesity groups. Conclusions : From these results, it could be concluded that zymolysis-dietotherapy with herbal medication is effective on obesity care.

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