• The Korean Journal of Food And Nutrition
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• v.30 no.4
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• pp.830-840
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• 2017

Excessive body weight gain during the growth period of early life may predispose individuals towards obesity and metabolic disorder in later life. We investigated the possibility of using the food efficiency ratio as an early indicator for predicting susceptibility to diet-induced obesity and insulin resistance. Four-week-old, prepubertal, male Sprague Dawley rats were divided into obesity-prone and obesity-resistant groups based on food efficiency ratio values after five days on a high-fat diet. Metabolic parameters measured after 2, 6, and 10 weeks, and specific phenotypes were compared with each group. Obesity-prone rats had higher increases in body weight and fat mass compared to obesity-resistant rats over the study period. Obesity-prone rats became glucose intolerant early in this study and remained so throughout the experimental period, with increases in fat weight and leptin levels occurring first, followed by increases in insulin level. Gluconeogenesis and insulin resistance significantly increased in obesity-prone groups in which activities of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase were increased and glucokinase activity decreased. Higher food efficiency ratio at an early age was closely correlated with body fat accumulation, hyperleptinemia, and hyperinsulinemia of middle and elderly age. We suggest a high food efficiency ratio in prepubertal subjects may be a useful predictor of future obesity and insulin resistance.

• The Journal of Korean Society for Radiation Therapy
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• v.7 no.1
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• pp.133-145
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• 1995

1. Purpose : 30 patients with uterine cervical cancer who had been treated at Department of radiation Oncology of Korea university Hospital from June, 1, 1994. to December. 31, 1994. were analyzed to the radiation field accuracy using verification films. 2. Methods and Materials : 30 patients were divided by 6 groups, 5 patients respectively : Group (1) : Standard physique, supine not-fixed Group (2) : Standard physique, supine fixed Group (3) : Obesity physique, supine, not-fixed Group (4) : Obesity physique, supine, not-fixed Group (5) : Obesity physique, prone, not-fixed Group (6) : Obesity physique, prone, fixed All groups were taken verification fimls during the whole treatment period, and it compared with simulation films and portal fimls, 3. Results : This results suggest that all patients should be immovilized and especially obesity physique patients should be treated by prone position in order to reduce radiation field discrepancy. In addition, this results should help to prescribe appropriate safty margins for patients simulation.

• Journal of radiological science and technology
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• v.22 no.2
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• pp.9-15
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• 1999

The aim of this study is to measure the application of prone compression study using compression paddle for obese patients in upper gastrointestinal series. Prone compression study using compression paddle was performed in fifty patients, who were not examined completely erect compression study for obesity. The radiographs of stomach were classified into the lower, middle, and high body and then we gave five points included 'very poor', 'poor', 'suspicious', 'good', and 'complete' according to level of detection for area gastrica and mucosal fold. Statistic analysis was performed using T-test and ANOVA, and confidence rate was fixed in 95%(P<0.05) for the significance. The results were as follows : 1. The compression marks on high body was 'poor' grades in erect and prone compression study. The points were 1.64 and 1.86, respectively. 2. The compression marks on middle body was 1.68 in erect compression study, and 'suspicious' in prone compression study. 3. The compression marks on lower body was 'poor' in erect compression study, and 'good' in prone compression study. 4. There was a high statistic signification between the two study on middle and lower body except for high body(P<0.01). 5. The average abdominal thickness of subjects was 23.98 centimeter. There was no statistic signification between the difference of average marks by the abdominal thickness(P>0.05). As these results, the prone compression study in upper gastrointestinal serie seem to be an useful study for obese patients, because it decreases pain and the feeling of uneasiness, and improve compression efficiency remarkably.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1241-1246
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• 2009

It has been suggested that Tae-Eum peoples are prone to obesity. Although extensive clinical observations have shown this tendency in Sasang Constitutional Medicine (SCM), no scientific hypothesis has been proposed to delineate its mechanism. According to SCM theory, Tae-Eum peoples have a hypoactive lung system and a hyperactive liver system. In this paper we propose a new hypothesis explaining the tendency of obesity in Tae-Eum people in the viewpoint of cell physiology. The hypoactive lung system might imply an attenuated 'respiration' at the cell/subcell level, namely mitochondrial oxygen consumption. Because a functional weakness in mitochondria energy metabolism indicates intrinsic hypo-activity in the consumption (or production) of metabolic energy, we deduced that the tendency can easily induce body weight gain via an increase in anabolism. This relation is also introduced in the graph of cellular metabolic power against body weight. To test this hypothesis, we analyzed the clinical data with 863 subjects. Statistical analysis of the data showed that Tae-Eum peoples had relatively a lower cellular metabolic power, and that the percentage of peoples with BMI>25 was significantly higher than that of the other constitutional types.

• Integrative Medicine Research
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• v.6 no.3
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• pp.254-259
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• 2017

Background: Those classified as Tae-Eum (TE)-type people in Sasang constitutional medicine (SCM) are prone to obesity. Although extensive clinical observations have confirmed this tendency, the underlying physiological mechanisms are unknown. Here, we propose a novel hypothesis using integrative physiology to explain this phenomenon. Methods: Hypoactive lung function in the TE type indicates that respiration is attenuated at the cellular level - specifically, mitochondrial oxygen consumption. Because a functional reduction in cellular energy metabolism is suggestive of intrinsic hypoactivity in the consumption (or production) of metabolic energy, we reasoned that this tendency can readily cause weight gain via an increase in anabolism. Thus, this relationship can be derived from the graph of cellular metabolic power plotted against body weight. We analyzed the clinical data of 548 individuals to test this hypothesis. Results: The statistical analysis revealed that the cellular metabolic rate was lower in TEtype individuals and that their percentage of obesity (body mass index >25) was significantly higher compared to other constitutional groups. Conclusion: Lower cellular metabolic power can be an explanation for the obesity trend in TE type people.

• The Journal of Pediatrics of Korean Medicine
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• v.33 no.1
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• pp.46-57
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• 2019

Objectives The purpose of this study is to evaluate the growth of low income and multicultural families' children in Dae-jeon area via growth indices, obesity indices and metabolic risk factors. Methods Six to 13-year-old children were enrolled in this study. Children were examined their body composition and bone age and their blood samples were collected. Results Current growth of children in low income and multicultural families was under the average compared to that of average children in the same age. Also, boys were more prone to be overweight than girls and their skeletal maturity was more rapidly progressing. Conclusions Intensive management and more training in regards to exercise and eating habits will be needed to low income and multicultural families' children.

• Korean Journal of Community Nutrition
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• v.11 no.2
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• pp.279-288
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• 2006

The role of free radicals in the progression of many diseases and aging has been given a great attention and total antioxidant status (TAS) has shown to be reduced with aging. The incidence of hypertension has shown to be relatively high in the aged population, and it is known to be associated with increased obesity and oxidative stress. The aim of this study was to examine the obesity indices and the total antioxidant status in hypertensive elderly (64y$\alpha$-tocopherol, $\beta$-carotene and ascorbic acid did not show their significant correlations with TAS. These results showed that the hypertensive elderly are prone to be obese and to have increased TAS. Due to unknown factors affecting TAS values, measurement of plasma TAS as a sole indicator of total antioxidant capacity is limited to fully understanding changes in the body's free radical trapping power. However, the results from the current study may suggest that hypertension and/or obesity might increase oxidative stress, followed by increased the body's total antioxidant defense system.

• Journal of Yeungnam Medical Science
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• v.39 no.4
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• pp.285-293
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• 2022

Background: This study was conducted to analyze the effects of low skeletal muscle mass index (SMI) and obesity on aging-related osteoarthritis (OA) in the Korean population. Methods: A total of 16,601 participants who underwent a dual-energy X-ray absorptiometry and 3,976 subjects with knee X-rays according to the modified Kellgren-Lawrence (KL) system were enrolled. Knees of ≥KL grade 2 were classified as radiologic OA. The severity of joint space narrowing (JSN) was classified by X-rays as normal, mild-to-moderate, and severe JSN in radiologic OA. The subjects were grouped as normal SMI (SMI of ≥-1 standard deviation [SD] of the mean), low SMI class I (SMI of ≥-2 SDs and <-1 SD), and low SMI class II (SMI of <-2 SDs). Obesity was defined as a body mass index (BMI) of ≥27.5 kg/m². Results: The modified KL grade and JSN severity were negatively correlated with the SMI and positively correlated with BMI and age. The SMI was negatively correlated with age. JSN severity was significantly associated with a low SMI class compared to a normal SMI, which was more prominent in low SMI class II than class I. Obesity was significantly associated with more severe JSN, only for obesity with a low SMI class. Furthermore, patients with a low SMI class, regardless of obesity, were prone to having more severe JSN. Conclusion: This study suggested that a low SMI class was associated with aging and that an age-related low SMI was more critically related to the severity of JSN in OA.

• The Journal of Pediatrics of Korean Medicine
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• v.28 no.4
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• pp.147-156
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• 2014

Objectives The purpose of this study is to evaluate the current growth via Growth indices, Obesity indices, Metabolic risk factors of Multicultural Families' Children in Dae-jeon area. Methods 5 to 12 year old children from 56 multicultural families were enrolled in this study, and were examined their bone age and body composition, and have received blood tests. Results 1. In Growth indices, average height percentile was $53.64{\pm}25.59%$. The AHP and MPH respectively, were converted into 20 years old adult height percentile, AHP of a girls was 40 percentile and MPH was 19 percentile, AHP of boys was 57 percentile and MPH was 21 percentile. 2. In Obesity indices, average of BMI pecentile was $44.16{\pm}29.52$; low-weight group (6 boys, 4 girls), normal-weight group (20 boys, 18 girls), over-weight group (8 girls). Average PWH was $100.51{\pm}15.66%$; low-weight group (9 boys, 5 girls), normal-weight group (14 boys, 15 girls), over-weight group (3 boys, 5 girls), obesity group (5 girls). 3. The results of the relationship between Growth indices and Obesity indices, 1) As RH percentile in boys was increased, skeletal maturity, AHP and AHP-MPH were also increased. Similarly, as RH percentile in girls was increased, skeletal maturity, AHP and AHP-MPH were also increased. 2) As skeletal maturity in boys was increased, BMI percentile was also increased. As skeletal maturity in girls was increased, AHP-MPH was decreased but had no significant differences. Conclusions Current growth of children in multicultural families was above the average when compared to that of average children in the same age. It was predicted that the boys' height were still above the average adult height, but the girls' height were below the average. Also this study showed that girls were more prone to be overweight than boys, thus requiring more intensive management and training in regards to eating habits and exercise.

• Journal of Digital Convergence
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• v.19 no.6
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• pp.429-438
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• 2021

This study aims to prevent maternal social isolation by analyzing the causes of postpartum obesity and postpartum depression and stress in Korea. Gneral characteristics of mothers as a result of the study: 91.1% (102 people) answered that they had social experience, and only 8% (9 people) answered that they had no social experience. In the question of whether to return to society, 17.9% responded that they have already returned, 54.5% did not, and 18.8% were on maternity leave. As a result of examining the level of BMI increase among mothers through chi-square test of BMI changes before and after childbirth and general characteristics, 55% experienced below-average BMI increase; 45% experienced above-average BMI increase. Those in their 30s accounted for 40.2%, and those in their 40s accounted for 57.1%. Postpartum obesity and maternal psychological status (t-test): Mothers with postpartum obesity were more hypersensitive (t = -1.997, p = 0.048) and more prone to suffer from hard breathing (t = -1.930, p = 0.056), emptiness (t = -2.673, p = 0.010), and body numbness (t = -2.315, p = 0.024) than mothers who are not suffering from not postpartum obesity. Per the results of postpartum BMI increase and maternal psychological state (t-test) analysis, mothers with an average increase in postpartum BMI were more depressed than mothers who did not. Research Results - Postpartum obesity due to pregnancy and childbirth has been identified as an important individual cause affecting mental and physical problems after childbirth. In conclusion, I also think that the government should support the management of maternal obesity and the elimination of depression through the results of this study.