• 제목/요약/키워드: organic integrity

검색결과 53건 처리시간 0.032초

Effects of Preparation Method and Evaluations on Structural Integrity in Model Antigen-Containing Biodegradable Microspheres for Vaccine Delivery

  • Cho Seong-Wan;Kim Young-Kwon
    • 대한의생명과학회지
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    • 제12권3호
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    • pp.177-183
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    • 2006
  • To demonstrate the effect of formulation conditions and evaluations of structural integrity from ovalbumin containing poly lactide glycolide copolymer (PLGA) microspheres for Vaccine delivery, OVA microspheres were prepared by a W/O/W multiple emulsion solvent extraction technique. Dichloromethan (DCM) and Ethyl acetate (EA) were applied as an organic phase and poly vinyl alcohol (PVA) as a secondary emulsion stabilizer. Microspheres were characterized for particle size, morphology (optical microscopy and Scanning Electron Microscope (SEM)). Protein denaturation was evaluated by size exclusion chromatography (SEC), SDS-PAGE and isoelectric focusing (IEF). Residual organic solvent was estimated by gas chromatography (GC) and differential scanning calorimetry (DSC). Optical photomicrograph and SEM revealed that micro spheres were typically spherical but various morphologies were observed. Mean particle size $(d_{vs})$ of microspheres were in the range of $3{\sim}50{\mu}m$. Also, The protein stability was not affected by the fonnulation process and residual organic solvent was beyond the detection below 0.1ppm. These results demonstrated that micro spheres might be a good candidate for the parenteral vaccine delivery system.

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콘크리트 보호용 그래핀/에폭시 도료개발을 위해 표면개질한 그래핀 나노플레이트의 유기용매 분산특성 (Dispersion Characteristics of Surface-Modified Graphene Nanoplate in Organic Solvent for Development of Graphene / Epoxy Paint to Protect Concrete)

  • 서원우;김규용;윤민호;이상규;황의철;손민재
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2017년도 춘계 학술논문 발표대회
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    • pp.244-245
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    • 2017
  • This study aims to develop high durability graphene / epoxy paint for durability improvement of construction structure. For the development of graphene / epoxy coatings, first, graphene must remain stable in the polymer. Second, the integrity of graphene and polymer should be ensured. Accordingly, in order to obtain dispersibility, surface modification of graphene nanoplate(GnP) with CH and COOH functional groups and its dispersibility in organic solvents were investigated. Also, Fourier Transform Infrared Spectroscopy(FT-IR) analysis and Atomic Force Microscope(AFM) analysis were performed to confirm whether the functional groups were synthesized by surface modification. As a result, FT-IR and AFM analysis did not confirm the surface modification, but GnP was found to be stable when dispersed in an organic solvent.

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유기식품 시장의 확대를 위한 소비자 기대 충족 요건 (Requirements for Meeting Consumer Expectations to Expand the Market for Organic Products)

  • 피어슨 데이비드;정만철
    • 한국유기농업학회지
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    • 제20권4호
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    • pp.491-502
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    • 2012
  • The world's food production systems are becoming an area of great concern for both human and ecological health. Research has identified that one of the greatest threats to sustainability is conventional industrial agricultural systems and the high energy and material cost they require to function. The organic food movement is contributing as promising alternative to the current dominant model. Over the last 50 years it has developed into the most visible brand for a healthier and more environmentally sustainable food system. However, to achieve its full potential there are still a number of hurdles which must be overcome to make organic products a more viable and appealing option for consumers. This paper provides an overview of key research that has been conducted on why consumers are buying organic products, what they are buying and what is preventing them from purchasing more. It concludes that the key challenge is for the organic food movement to convince existing consumers of the superior 'value' of its products. In addition there are a number of methodological issues associated with analysing the market for organic products as well as issues of limited distribution, intermittent availability and high prices that are currently preventing increases in sales. Recognition and management of these barriers could contribute to more effective targeted research into consumer food purchasing motivations and subsequently the development of more sophisticated marketing strategies that assist in maintaining integrity with consumers and fending off challenges from conventional as well as other complementary food systems such as local food movement. And finally to achieve these market growth strategies the organic food movement will need to cope with its diverse constituency - ranging from global corporates through to local production and consumption - and provide attractive opportunities to individuals and business at all stages in supply chain whilst retaining credibility with government to ensure ongoing policy support.

미국과 일본의 CSA운동의 등장, 유형 및 활동사례 (Study on Activity, Type and Establishment of Community Supported Agriculture in USA and Japan)

  • 정진영;손상목;김영호
    • 한국유기농업학회지
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    • 제9권1호
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    • pp.1-16
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    • 2001
  • With increasing global concern that intensively synthetic-chemical based farming systems accelerated the decline in environmental quality, the sustainability of modem agriculture became the subject of great concern. It is well known that the movement of Community Supported Agriculture(CSA) has been contributed significantly to the development of organic agriculture in USA and Japan. It was supposed that CSA could be one of the best way to promote the movement of organic agriculture since there is little reliability on the organically grown food by consumer. In this paper it was focussed to study the movement of CSA in USA and Europe in order to provide an idea for establishment and movement of CSA in Korea to support the organic agriculture. In a CSA system, the farmer grows food for a group of shareholders who pledge to buy a portion of the farm's crop that season. This arrangement gives growers up-front cash to finance their operation and higher prices for produce, since the middleman has been eliminated. For most shareholder for CSA saving money is a secondary consideration, but fresh safe products and environmentally sound farming system. People become shareholder of CSA since they expect an organic farming which can ; \circled1protect the environment, minimize pollution, promote health, \circled2replenish and maintain long-term soil fertility by providing optimal conditions for soil biological activity, \circled3maintain diversity within the farming system and its surroundings and protect plant and wildlife habit, \circled4recycle materials and resources to the greatest extent possible within the farm and its surrounding community, \circled5maintain the integrity of organic food and processed products through each step of the process from planting to consumption, \circled6develop and adopt new technologies with consideration for their long range social and ecological impact. In all CSAs, the farmer develops a crop plan and a budget, which details costs for a growing season, including fair wages for the farmers. Experienced Information on increasing shareholder retention, the future of CSA, and getting started such as ideas for ongoing marketing, printed materials that set realistic expectations, working members, production, pick-up and delivery, setting prices, and receiving feedback were also briefly introduced.

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유기성 폐기물 반응기 내부 교반 축 및 블레이드 건전성 평가 (Integrity Evaluation of Agitating Axis and Blade in the Organic Waste Reactor)

  • 윤유성
    • 한국안전학회지
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    • 제32권2호
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    • pp.1-6
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    • 2017
  • Modern society has been experiencing by population growth and urbanization that bring, a change of eating habits which has occurred a various types of waste in a large amount. Even though these wastes are required an immediate treatment with difficulties unsanitary handling and existing waste treatment method are by incineration, fermentation, drying and etc. however a bad smell occurs after the treatment that need's a lot of energy in processing organic wastes with high moisture contents and wasteful and inefficient problem. The strength assessment of the organic waste agitating vessel is required in terms of safety due to the differences of loading on the shaft that was treated by agitating the mixture of food waste. The damage of agitating axis is depended on steam pressure, temperature condition and the force moment that exerted by the food waste. Thus the strength assessment and stability evaluation are very important, especially to handle a hard waste. In this study the rotation capacity of agitation is about 5 tons considering general structural rolled steel pressure vessel strength and steam pressure. The purpose is to estimate the safety and strength evaluation for a agitator axis and impellers according to the rotating angle of the axis under the condition of the 3.2 ton capacity reactor.

간척지 염해토양의 Phytoremediation에 의한 제염 (Desalinization of Salt-affected Soil by Phytoremediation)

  • 손재권;송재도;신원태;이수환;류진희;조재영
    • 한국유기농업학회지
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    • 제24권3호
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    • pp.583-598
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    • 2016
  • Salted-affected soil is a major environmental constraint with severe negative impacts on agricultural productivity and sustainability in reclaimed tidelands. This review focuses on the phytoremediation of reclaimed tidelands. We address the process of phytoremediation of these soils, comparison of phytoremediation with other amelioration approaches, driving forces contributing to the process, selection of phytoremediation crops, and the role of cropping in securing environmental integrity under salt-affected soils.

Bio-Inspired Synthesis of a Silicate/PMMA Composite

  • Nam, Kyung Mok;Lee, Yoon Joo;Kwon, Woo Teck;Kim, Soo Ryong;Shin, Dong-Geun;Lim, Hyung Mi;Kim, Hyungsun;Kim, Younghee
    • 한국세라믹학회지
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    • 제51권1호
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    • pp.7-10
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    • 2014
  • Abalone shell is composed of 95 wt% $CaCO_3$ platelets and 5 wt% of a protein-rich organic matrix which acts as an adhesive layer, connecting aragonite tablets, thus maintaining the structural integrity of the composite. By mimicking abalone shell, we prepared a silicate plate/polymer nanocomposite by infiltrating PMMA between silicate layers and warm-pressing them at $200^{\circ}C$ for 1 h under 15 tons to make organic-inorganic composite materials. To examine the organic-inorganic composite materials after the warm-pressing procedure, the composite sample was analyzed with FE-SEM and TG. The bending strengths and densities of the composites prepared by a silicate plate and PMMA after the warm-pressing process were ~140 MPa and 1.5, respectively.

Acid-Base Bifunctional Metal-Organic Frameworks: Green Synthesis and Application in One-Pot Glucose to 5-HMF Conversion

  • Zhang, Yunlei;Jin, Pei;Meng, Minjia;Gao, Lin;Liu, Meng;Yan, Yongsheng
    • Nano
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    • 제13권11호
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    • pp.1850132.1-1850132.14
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    • 2018
  • The direct synthesis of metal-organic frameworks (MOFs) with acidic and basic active sites is challenging due to the introduction of functional groups by post-functionalization method often jeopardize the framework integrity. Herein, we report the direct synthesis of acid-base bifunctional MOFs with tuning acid-base strength. Employing modulated hydrothermal (MHT) approach, microporous MOFs named $UiO-66-NH_2$ was prepared. Through the ring-opening reaction of 1,3-propanesultone with amino group, $UiO-66-NH_2-SO_3H-type$ catalysts can be obtained. The synthesized catalysts were well characterized and their catalytic performances were evaluated in one-pot glucose to 5-HMF conversion. Results revealed the acid-base bi-functional catalyst possessed high activity and excellent stability. This work provides a general and economically viable approach for the large-scale synthesis of acid-base bi-functional MOFs for their potential use in catalysis field.

글로벌 배선 적용을 위한 UV 패턴성과 UV 경화성을 가진 폴리실록산 (Organic-inorganic Hybrid Dielectric with UV Patterning and UV Curing for Global Interconnect Applications)

  • 송창민;박해성;서한결;김사라은경
    • 마이크로전자및패키징학회지
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    • 제25권4호
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    • pp.1-7
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    • 2018
  • As the performance and density of IC (integrated circuit) devices increase, power and signal integrities in the global interconnects of advanced packaging technologies are becoming more difficult. Thus, the global interconnect technologies should be designed to accommodate increased input/output (I/O) counts, improved power grid network integrity, reduced RC delay, and improved electrical crosstalk stability. This requirement resulted in the fine-pitch interconnects with a low-k dielectric in 3D packaging or wafer level packaging structure. This paper reviews an organic-inorganic hybrid material as a potential dielectric candidate for the global interconnects. An organic-inorganic hybrid material called polysiloxane can provide spin process without high temperature curing, an excellent dielectric constant, and good mechanical properties.

조류가 발생한 수질에 과망간산나트륨과 차아염소산나트륨이 세포 손상도 및 부산물 발생에 미치는 영향 비교 (Comparison of sodium permanganate and sodium hypochlorite on algae-containing water: algae cell integrity and byproduct formation)

  • 양보람;홍석원;최재우
    • 상하수도학회지
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    • 제36권5호
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    • pp.249-260
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    • 2022
  • The effect of permanganate oxidation was investigated as water treatment strategy with a focus on comparing the reaction characteristics of NaOCl and sodium permanganate (NaMnO4) in algae (Monoraphidium sp., Micractinium inermum, Microcystis aeruginosa)-contained water. Flow cytometry explained that chlorine exposure easily damaged algae cells. Damaged algae cells release intracellular organic matter, which increases the concentration of organic matter in the water, which is higher than by NaMnO4. The oxidation reaction resulted in the release of toxin (microcystin-LR, MC-LR) in water, and the reaction of algal organic matter with NaOCl resulted in trihalomethanes (THMs) concentration increase. The oxidation results by NaMnO4 significantly improved the concentration reduction of THMs and MC-LR. Therefore, this study suggests that NaMnO4 is effective as a pre-oxidant for reducing algae damage and byproducts in water treatment process.