• Journal of the Korean Data and Information Science Society
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• v.25 no.5
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• pp.999-1009
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• 2014

Hierarchical clustering analysis helps easily exploring massive microarray data and understanding biological phenomena with dendrogram. But, because hierarchical clustering algorithms only consider the absolute similarity, it is difficult to illustrate a relative dissimilarity, which consider not only the distance between a pair of clusters, but also how distant are they from the rest of the clusters. In this study, we introduced the relative hierarchical clustering method proposed by Mollineda and Vidal (2000) and compared hierarchical clustering method and relative hierarchical method using the simulated data and the real data in the various situations. The evaluation of the quality of two hierarchical methods was performed using percentage of incorrectly grouped points (PIGP), homogeneity and separation.