• Title/Summary/Keyword: period of the disease

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A Chinese Case of Coronavirus Disease 2019 (COVID-19) Did Not Show Infectivity During the Incubation Period: Based on an Epidemiological Survey

  • Bae, Jong-Myon
    • Journal of Preventive Medicine and Public Health
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    • v.53 no.2
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    • pp.67-69
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    • 2020
  • Controversy remains over whether the coronavirus disease 2019 (COVID-19) virus may have infectivity during the incubation period before the onset of symptoms. The author had the opportunity to examine the infectivity of COVID-19 during the incubation period by conducting an epidemiological survey on a confirmed patient who had visited Jeju Island during the incubation period. The epidemiological findings support the claim that the COVID-19 virus does not have infectivity during the incubation period.

Comparison of Effectiveness of Breathing Intervention Program for Improvement of Pulmonary Functions according to Prevalence Period in Patients with COPD (만성폐쇄성폐질환 환자의 폐기능 향상을 위한 호흡중재기법의 유병기간별 비교)

  • Kim, Yong-Nam
    • The Journal of Korean Physical Therapy
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    • v.24 no.5
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    • pp.355-361
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    • 2012
  • Purpose: The purpose of this study was to evaluate the effectiveness of pulmonary rehabilitation on lung function and fatigue in persons with chronic obstructive pulmonary disease (COPD). Methods: Thirty one persons with COPD participated in this study. Four groups were allocated as follows: experimental group 1 (under 10 years of the post-disease period), control group 1 (under 10 years of the post-disease period), experimental group 2 (over 10 years of the post-disease period), and control group 2 (over 10 years of the post-disease period). Results: Forced expired volume in one second (FEV1) % pred and lactic acid showed improvement in experimental group 1 and experimental group 2 after training. Control group 1 and control group 2 did not show improvement of FEV1% pred and lactic acid after training. However, FEV1% pred and lactic acid in experimental group 1 were not significantly different, compared with the experimental group. Conclusion: Results of our study suggest that implementation of a pulmonary rehabilitation program resulted in improvement of lung function and fatigue in persons with COPD not related to the post-disease period.

Serological Survey of Major Avian Viral Diseases Related with Egg Production in Commercial Chicken Flocks in Korea

  • Jang, Hae-Sun;Lee, Hae-Rim;Koo, Bon-Sang;Jeon, Eun-Ok;Han, Moo-Sung;Min, Kyung-Cheol;Lee, Seung-Baek;Bae, Yeonji;Cho, Sun-Hyung;Mo, Jong-Suk;Kim, Jong-Nyeo;Mo, In-Pil
    • Korean Journal of Poultry Science
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    • v.41 no.3
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    • pp.173-179
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    • 2014
  • While use of mass rearing systems improved poultry production, chances of exposing to contagious diseases have been increased, making flocks more vulnerable to diseases. Diseases of interest which affects egg production adversely include Low pathogenic avian influenza (LPAI), Infectious bronchitis (IB), Avian meta-pneumoviral infection (aMPV) and Egg drop syndrome'76 (EDS'76). This report collected and analyzed 5,385 serum samples, which were collected from 1,330 different chicken flock, provided by Chungbuk National University, Avian Disease Laboratory at 2009. Serums were analyzed based on rearing stages; 0~1.3weeks (wks) (maternal antibody period), >1.3~3 wks (starting period), >3~10 wks (growing period), >10~22 wks (developing period), >22~40 wks (peak laying period), >40~60 wks (late laying period) and over 60 wks (post-molting period). Results showed the 99.7% of the tested flocks were immunized against ND and73.8%, 97.1%, 78,2% and 78% of the flocks were immunized against other 4 agents (LPAI, IB, EDS'76, aMPV). Maternal antibody was transferred to enough quantity for NDV. Generally, antibody titers which were developed at 22 weeks were stabilized permanently for life. In case of IB and aMPV, infection titer emerged as early as 10 weeks and the titer was increased from 99.4% to 100% for life. EDS76 showed increase in titers, reflecting decreased frequency of vaccination programs. Overall, this study displayed general trends of major viral disease in layers, but considering the trend of development of preventive measures and evolution of pathogens, conducting serological surveys on a regular basis is important.

Clinical Comparison Study on Bell's Palsy Patients by the Period of Disease (병력기간과 말초성 안면신경마비와의 상관성 연구)

  • Hong, Jang-Mu;Shin, Kyung-Min;Seo, Gwang-Myung;Choi, Soon-Young;Bae, Kwang-Rok;Park, Ji-Young;Baek, Yong-Hyeon;Nam, Dong-Woo;Lee, Yun-Ho
    • Journal of Acupuncture Research
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    • v.26 no.2
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    • pp.71-77
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    • 2009
  • Objectives : This study was designed to evaluate the influence of the period of disease on Bell's palsy patients Methods : We investigated 40 cases of patients with peripheral facial palsy who visited Yumin Oriental Hospital from 1st January to 31st August, 2008 with both oriental and western medical therapy and classified them as period of disease. The period of disease of Group A was within 3 days. The period of disease of Group B was from 4 to 10days. We evaluated the treatment effect of each group by House-Brackmann grade before treatment and 1, 2 week treatment. Results: 1. There was a statistical significant difference in period of disease between Group A and Group B. 2. After 1 week treatment, Group A showed more recovery compared with Group B. 3. After 2 week treatment, there was no statistical significant difference in House-Brackmann grade between Group A and Group B Conclusions : These results suggest that early treatment could be more effective in recovery of Bell's palsy.

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Developing Prevention System of Overseas Infectious Disease Based on MERS and Zika Virus Outbreak (중동호흡기증후군과 지카바이러스의 대응사례분석을 통한 해외유입 신종감염병 예방시스템 구축 방안)

  • Kim, Ja Young;Bang, Joon Seok
    • Korean Journal of Clinical Pharmacy
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    • v.26 no.4
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    • pp.330-340
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    • 2016
  • Objective: The outbreak of Middle East Respiratory Syndrome (MERS) started in South Korea in May 2015 and the end of crisis was declared in December 2015 by Korea Centers of Disease Control and Prevention (KCDC). However, Zika virus emerged in less than 2 months following MERS and showed higher mortality than other countries. This study is to assess the current prevention system of overseas infectious diseases, based on MERS and Zika virus outbreak and to suggest effective response system for the future. Methods: We conducted two surveys on medical specialists working at tertiary general hospitals regarding the effectiveness of responding system by KCDC against MERS and Zika virus and education in individual medical institutions using 5-Likert points. Response system was examined in three different periods as initial period, spreading period, and post disease period. Results: Although medical specialists received the notifications in initial period, no practical prevention was proven to be placed in responding stage by medical facilities (averagely 3.5/5 points in total and sub-analyses). During spreading period, there were several academic seminars conducted, which were evaluated as helpful. In post disease period, all answered that there were changes on patient treatment in all medical facilities, with mainly report system and the treatment regulations in case of suspicious patients for infection. Only 49% respondents answered positive on the possibility of initial responses. For questionnaire items regarding Zika virus, all answered that there were notifications prior to the first outbreak of the infected patient. Eighty% of respondents were aware of 'the Guideline system for traveling to dangerous areas', and answered that the system was moderately effective (averagely 3.8/5 points in total). For the effectiveness of prevention measures for foreign novel disease by KCDC, the average point was 3.0 in both of total and sub-analyses. Conclusion: There is not enough response system to prevent infectious disease in medical institutional and governmental levels in Korea. It would warrant the modification of overall medical system to improve preventive measures for initial spread of such diseases.

Effect of Temperature and Leaf Wetness Period on the Components of Resistance to Late Leaf Spot Disease in Groundnut

  • Pande, Suresh;Rajesh, T.Ratna;Kishore, G.Krishna
    • The Plant Pathology Journal
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    • v.20 no.1
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    • pp.67-74
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    • 2004
  • A complete understanding of the epidemiological factors required for optimum for disease development facilitates the design of effective and reliable screening techniques and also disease prediction models. An attempt was made to study the effects of different temperatures ($15-35^{\circ}C$) and leaf wetness periods (4-24 h) on the development of late leaf spot (LLS) in three groundnut genotypes differing in their susceptibility to LLS infection. Irrespective of the genotype, the disease progress evaluated based on different components of resistance was maximum between $15-20^{\circ}C$ and minimum between $20-25^{\circ}C$. At temperatures $\geq$$30^{\circ}C$, LLS development was insignificant. The overall severity of LLS increased with an increase in the leaf wetness period from 4 h to 12 h a day. Further increase of wetness period to 16 h resulted in a rapid increase in the severity. Thereafter, the disease severity gradually decreased with an increase in the wetness period. The effect of temperature and wetness periods on the individual component of disease quantification was not uniform compared between genotypes with different levels of susceptibility/resistance to LLS infection. The results of this study indicate that temperature and leaf wetness period are critical in late leaf spot screening programs since the expression of disease symptoms measured from disease initiation till defoliation, varied differently in the test genotypes with respect to change in these two parameters.

Palliative surgery for cyanotic heart disease: 102 cases (선천성 청색증 심장병에 대한 고식적 수술: 102례 보)

  • 진성훈
    • Journal of Chest Surgery
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    • v.17 no.1
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    • pp.26-31
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    • 1984
  • From Jan. 1962 to Aug. 1983, one hundred patients with cyanotic heart disease underwent various palliative operations at the department of thoracic and cardiovascular surgery, S.N.U.H. In the period from Jan. 1962 to Dec. 1973, in which the open heart surgery was not routinely performed, sixty-two operations including 2 cases of second shunt operation were performed in sixty patients, and all of them were tetralogy of Fallot except three cases. Various palliative procedures such as Glenn, Brock, Waterston and Blalock-Taussing operation were used in this period with overall mortality rate of 16%. In the period from Jan. 1980 to Aug. 1983, forty patients with cyanotic heart disease were operated and majority of them was complex anomalies. Only Blalock-Taussing operation was used in this period with a mortality rate of 20%. These two groups of patients were compared according to age, diagnosis and results of operations, and it appears that Blalock-Taussing operation is effective palliation for patients with cyanotic heart disease, especially with complex anomaly, with an acceptable mortality.

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Aortic valve replacement in the patient with rheumatic heart disease (류마치스성 심장질환 환자에서 대동맥판막치환)

  • An, Jae-Ho;Lee, Yeong-Gyun
    • Journal of Chest Surgery
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    • v.17 no.3
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    • pp.346-355
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    • 1984
  • 77 cases of Aortic Valve Replacement, which were composed of 64 rheumatic valvular heart disease and 13 combined congenital heart disease, were operated at Seoul National University Hospital for Aortic valvular disease during the period from June 1968 to December 1983. Among these 64 rheumatic aortic valvular heart disease cases, 8 patients were expired during and immediate after operation and overall mortality rate was 12.5%. For more precise remarks, these patients were divided into two periodic groups, 1st period [from 1968 to 1976] and 2nd [from 1977 to 1983] when annual open heart surgery were over 100 cases, and in 1st period three of four patients were died and in 2nd period five of sixty patients were died and its mortality rate was 8.3%. There were 12 cases of postoperative complication, which were 3 cases of remaining other valvular heart disease required MVR, 2 paravalvular leaks [one of them got Redo AVR], 4 thromboembolism or problem of anticoagulant therapy, 2 late death due to SBE with replaced valve failure and one functional AS with small sized valve. Operative death was affected by pump-time and aortic cross-clamping time, heart size, Ejection Fraction, LVEDP and symptom duration, and other many factors may influence the survival rate. Improved operative technique and myocardial protection and meticulous evaluation of the preoperative patient status will make the AVR safer.

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Trends in Ischemic Heart Disease Mortality in Korea, 1985-2009: An Age-period-cohort Analysis

  • Lee, Hye-Ah;Park, Hye-Sook
    • Journal of Preventive Medicine and Public Health
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    • v.45 no.5
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    • pp.323-328
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    • 2012
  • Objectives: Economic growth and development of medical technology help to improve the average life expectancy, but the western diet and rapid conversions to poor lifestyles lead an increasing risk of major chronic diseases. Coronary heart disease mortality in Korea has been on the increase, while showing a steady decline in the other industrialized countries. An age-period-cohort analysis can help understand the trends in mortality and predict the near future. Methods: We analyzed the time trends of ischemic heart disease mortality, which is on the increase, from 1985 to 2009 using an age-period-cohort model to characterize the effects of ischemic heart disease on changes in the mortality rate over time. Results: All three effects on total ischemic heart disease mortality were statistically significant. Regarding the period effect, the mortality rate was decreased slightly in 2000 to 2004, after it had continuously increased since the late 1980s that trend was similar in both sexes. The expected age effect was noticeable, starting from the mid-60's. In addition, the age effect in women was more remarkable than that in men. Women born from the early 1900s to 1925 observed an increase in ischemic heart mortality. That cohort effect showed significance only in women. Conclusions: The future cohort effect might have a lasting impact on the risk of ischemic heart disease in women with the increasing elderly population, and a national prevention policy is need to establish management of high risk by considering the age-period-cohort effect.

Effect of Foot-and-Mouth Disease on the Optimal Rearing Period of Hanwoo Steers (구제역이 한우 거세우의 적정 사육 기간에 미치는 영향)

  • Kim, Se-Hyuk;Kim, Tae-Kyun;Choi, Se-Hyun
    • Korean Journal of Organic Agriculture
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    • v.29 no.4
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    • pp.507-521
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    • 2021
  • The livestock farmers are producing under uncertainties such as Foot-and-Mouth Disease (FMD) and Free Trade Agreement (FTA). The purpose of this study is to strengthen the management capabilities of Hanwoo farmers to prepare them for the uncertainties just mentioned. To this end, this study was conducted to find the optimal rearing period in order to reduce the feed cost, which accounts for the largest portion of the operation cost of Hanwoo. Using the universal lattice model, 41,139 of 289,000 Hanwoo slaughter data from 2010 to 2019 were used for the FMD period and 246,605 heads for the general period. The results show that the maximum cutoff price of Hanwoo steer is 6,394,457 won at the 4th week of 27 months of age in general period, where as 6,242,752 won at the 2nd week of 26 months of age in the FMD period. Therefore, it is judged that it will be helpful for Hanwoo farms to maximize their business profits by slaughtering one month and two weeks earlier in the FMD period than in the general period. In addition, Hanwoo farmers need to break away from the conventional rearing method and improve their management efficiency through a more flexible rearing method.