• Title/Summary/Keyword: positive list system

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A comparative Analysis of Perception of Health Professionals and Pharmaceutical Companies on the Positive List System (선별등재 제도에 대한 전문가와 제약회사의 인식도 비교분석)

  • Ha, Dong-Mun;Lee, Su-Kyoung;Kim, Dae-Up;Chung, Kyu-Hyuck;Lee, Eui-Kyung
    • YAKHAK HOEJI
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    • v.54 no.4
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    • pp.309-315
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    • 2010
  • The Positive List System was newly introduced in South Korea as of January 2007. This study aims to survey and compare perception of and attitudes toward the Positive List System in the process of new drug listing that health professionals and pharmaceutical companies have. 50 professionals and 52 companies answered the questionnaire regarding health policy environments, policy decision/enforcement process, policy effects and satisfaction related to introducing the Positive List System. SAS 9.1 was used for statistical analyses. The results showed that participants had the general sympathy with health policy environments for the introduction of the Positive List System into South Korea. However, the response rates of policy decision/enforcement process and effects were negative and these tendencies were more striking in pharmaceutical companies. As for policy satisfaction, participants marked positive responses more than negative ones. It is necessary to remedy and supplement problems with policy decision/enforcement policy and effects revealed in this study and to improve the Positive List System through gathering opinions among groups and organization concerned.

Changes in the List of Drugs Covered by National Health Insurance after the Introduction of Positive List System in Korea (의약품 선별등재제도 도입 전후 건강보험 등재의약품의 특성별 현황)

  • Rhee, Jin-Nie;Heo, Ji-Haeng;Lee, Eui-Kyung
    • YAKHAK HOEJI
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    • v.55 no.4
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    • pp.338-344
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    • 2011
  • This study aimed to identify the changes in the list of drugs covered by national health insurance(NHI) after the introduction of positive list system (PLS) in Korea in December, 2006. Six-year (pre-policy:2004-2006, post-policy:2007-2009) lists of the NHI reimbursable drugs filed from Health Insurance Review and Assessment Service (HIRA) were analyzed. The total number of listed drugs as well as drug ingredients, and the average number of listed drugs per manufacturer decreased annually after the introduction of PLS. More than 8,000 drugs were delisted in the year 2007 right after the policy change. Prescription-only drugs occupied more than 85% of NHI listed drugs. The percentage of oral type of listed drugs has been increased to more than 60% after the policy change. Korean pharmaceutical manufacturers occupied more than 90% of listed drugs than multinational firms. The gap between Korean and foreign manufacturer in terms of the average number of newly listed drugs per manufacturer in each year has decreased two years after the PLS (Korean 7.7 vs. foreign 6.3 in 2009) as the price negotiation power of foreign firms has increased. The total number of listed drugs is expected to decrease in the future as the Korean government makes an effort to delist the unnecessary drugs that do not show cost-effectiveness.

Use of Economic Evaluation in the Listing and Pricing of Pharmaceuticals (의약품 보험 급여 및 가격 결정과 경제성 평가의 활용)

  • Lee, Tae-Jin
    • Journal of Preventive Medicine and Public Health
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    • v.41 no.2
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    • pp.69-73
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    • 2008
  • To curb a rapid increase in expenditures for pharmaceuticals, the Korean government introduced a positive list system and a negotiation process for drug prices at the end of 2006. Economic evaluation of pharmaceuticals has begun to have a pivotal role in the listing and pricing of drugs for the Korean National Health Insurance. There are some points to discuss regarding the use of economic evaluation in the listing and pricing in the context of the Korean system. First, the listing and pricing processes have been fragmented, evoking complaints from pharmaceutical companies and delaying the access of new drugs to patients. Second, there is a concern that the positive list system may limit the range and availability of drugs for patients to choose for treatment. Third, the time schedule for de-listing of existing drugs may not be realistic. Fourth, it is not always easy to provide reliable evidence of cost-effectiveness due to a lack of materials. Fifth, there is no consensus on the range of the ICER (incremental cost-effectiveness ratio) acceptable to the Korean society. In conclusion, in the near future, it will be necessary to evaluate the achievements that the economic evaluation has provided to the Korean society.

Demand Estimation for Manpower to Conduct Economic Evaluation on Pharmaceuticals with the Introduction of Positive List System in Korea (선별등재 도입에 따른 의약품 경제성평가 수행 인력의 수요 추계)

  • Lim, Jae-Young;Lee, Eui-Kyung
    • YAKHAK HOEJI
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    • v.51 no.2
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    • pp.126-132
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    • 2007
  • Demand for manpower of conducting pharmaco-economic evaluation was investigated. The priority order of conducting economic evaluation on the already listed drugs was set by the budget impact for health insurance by the therapeutic groups. Manpower demand was estimated by the Anatomical, Therapeutical, Chemical (ATC) code. The total number of economic evaluation on the already listed drugs is estimated to be 346 cases. Based on these numbers, at least 53${\sim}$102 of full-time-equivalent (FTE) manpower is needed for conducting economic evaluation per year in the following 5 years.

Control Effect of Plant Extracts Mixture on Metcalfa pruinosa (say) (Hemiptera: Flatidae) (식물추출물 혼합물의 미국선녀벌레 방제효과)

  • Lee, Young Su;Lee, Hee A;Lee, Hyun Ju;Choi, Jong Yoon;Lee, Sang-Woo;Lee, Young Soon
    • Korean journal of applied entomology
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    • v.58 no.4
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    • pp.281-282
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    • 2019
  • We have developed a composition containing three kinds of plant extracts (Deris, Citronella, and Cinnamon) and supplements (xanthan gum and silicone-based compounds) having high control effects on Metcalfa pruinosa. This composition had more than 90% of the nymph bug control effect in the ginseng plantation. In addition, since the insecticidal rate is high for other absorptive pests, it is considered that it can be used as a countermeasure against the implementation of the PLS (positive list system).

A Safety Survey on Pesticide Residues in Tropical Fruits Depending on Implementation of Positive List System (Positive List System 도입에 따른 열대과일류의 잔류농약 안전성 조사)

  • Kang, Hyang-Ri;Park, Yong-Bae;Do, Yung-Suk;Jeong, Jin-A;Lee, Seong-Bong;Cho, Sang-Hun;Lee, Hyo-Kyung;Son, Ji-Hee;Lee, Mi-Kyoung;Lee, Byoung-Hoon;Park, Jin-Hee;Yoon, Mi-Hye
    • Journal of Food Hygiene and Safety
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    • v.33 no.4
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    • pp.310-315
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    • 2018
  • Under the "Positive List System (PLS)," a uniform limit of 0.01 mg/kg is applied if the agricultural product does not have a Maximum Residue Limit (MRL) for a pesticide. The purpose of this research is to conduct residual pesticide monitoring on tropical fruits distributed in Gyeonggi-do to investigate the effects of PLS and provide basic materials for establishing MRLs of residual pesticides for tropical fruits produced in Korea. By inspecting 120 tropical fruits distributed in Gyeonggi-do according to Multi-class pesticide multi-residue methods, we detected sevenfruits from threekinds of banana, mangoes, and kiwis with six different residual pesticides. Azoxystrobin and chlorpyrifos were detected from bananas, chlorfenapyr from mangoes, and chlorothalonil, iprodione, and procymidone from kiwis. A single case of chlorfenapyr and chlorothalonil was found with a mango and a kiwi produced in Korea, respectively, and by applying PLS we found that they exceeded the MRL of residual pesticide. Thus, it is necessary to set the MRL of residual pesticides for tropical fruits produced in Korea.

ASTMMETRIC LIGHT CURVE OF W UMa TYPE ECLIPSING BINARY SYSTEM (비대칭 광도곡선을 갖는 W UMa 형 식쌍성)

  • 오규동
    • Journal of Astronomy and Space Sciences
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    • v.11 no.2
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    • pp.196-207
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    • 1994
  • Data on 27 W UMa systems having a asymmetric light curve so called O'Conell effect have been collected. Investigated 27 W UMa systems were classified into 12 positive and 15 negative type according to the shape of its asymmetric light curve. A list of members of the group, their current observational statue, and their physical and evolutional relationship to asymmetric W UMa type binaries are discussed.

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Evaluation of Residues of Fungicide Azoxystrobin in Radish based on Plant Back Interval Experiment (식물후방식재기간(PBI) 시험에 기반한 살균제 Azoxystrobin의 알타리무 중 잔류량 평가)

  • Yoon, Ji Hyun;Lim, Da Jung;Kim, Seon Wook;Kim, In Seon
    • Korean Journal of Environmental Agriculture
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    • v.41 no.1
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    • pp.1-8
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    • 2022
  • BACKGROUND: The pesticide residue in rotational crop is one of the main concerns to agricultural products because it has the potentiality of violating positive list system (PLS). Thus, the crops used for the rotational cultivation should be considered the pesticide residue patterns to meet the PLS guideline. In this study, we evaluated the residue patterns of fungicide azoxystrobin in radish based on plant back interval (PBI) experiment. METHODS AND RESULTS: Azoxystrobin was treated onto greenhouse soil at 217 g a.i./10a in two different regions. Radishes were sown onto the soil 30 and 60 days after azoxystrobin treatment. The soil and plant samples were subjected to a modified QuEChERS method and LC/MS/MS analyses to determine the residues of azoxystrobin. The methods were validated to meet the guidelines of the pesticide residue analysis recommended by the Rural Development Administration, Republic of Korea. Azoxystrobin was dissipated significantly in soil during the experimental period and found as a level less than 0.01 mg/kg in radish 30 and 60 days after treatment. Azoxystrobin residues in radish samples were lower than the maximum residue limit (MRL) for root vegetables. CONCLUSION(S): This study suggests 30 days as a PBI for rotational cultivation of radish in greenhouse soil that had been treated with azoxystrobin at a level of 217 g a.i./10a.

ISO9000 Certification Effect: Evidence from China

  • Liu, Yumin
    • International Journal of Quality Innovation
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    • v.9 no.3
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    • pp.15-27
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    • 2008
  • As a sign of international quality system, ISO9000 certification has been adopted by more and more enterprises. In recent five years, there have been 560,000 certified companies in Europe and America, and there have been more than 390,000 ones in China. It has being attracted many quality scholars' attentions whether ISO9000 certification can bring more benefits to certified companies or not. This paper investigates the ISO9000 certification effect on market performance by the samples from Chinese list companies in shanghai stock exchange. Considering ISO9000 certification as an event, a certification effect model will be set up by means of the event study method, which takes abnormal return rate as a basic indicator to measure the ISO9000 certification effect on Chinese market performance in different event times. Investigation results show that the Chinese certified companies have some positive effects on market performance in the short term. From a long standpoint, the relation between certification and performance has a positive trend.