• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10313-10317
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• 2015

Background: The purpose of the article was to analyze the years of potential life lost (YPLL) of women who died from breast and cervical cancer in the State of Paran$\acute{a}$, Southern Brazil. This was a temporal trend study (2000 to 2010) about the coefficients of mortality and the years of potential life lost in women aged 20 to 70 years. Materials and Methods: Data were obtained through the database of the Department of the Unified Health System (DATASUS) and the National Mortality Information System. Results: There was a loss of 125.075 YPLL due to breast cancer, with an average of 11.370 YPLL. Regarding cervical cancer, the figure obtained was 91.625 YPLL from 2000 to 2010, with an average of 8.329 YPLL. Increased risk of death from breast cancer was observed for women aged 50 to 59 years, with a significant increase among those in the age group from 40 to 49 years. There was an increased rate of cervical cancer among women 40 to 69 years. Conclusions: The risk of death grows with increasing age, being higher from 40 years. Prevention is paramount for both cancers. Thus, preventive measures are required and a reassessment of political strategies should be adopted.

• 보건행정학회지
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• 제19권4호
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• pp.33-52
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• 2009

Health promotion policies have needed to assess in detailed and evidence-based work to set a policy goal and clear future directions of health promotion in Korea. To identify the major factors related with health promotion, we assessed the associations between public health outcome (potential years of life loss, PYLL) and national health determinants. For this purpose, we used a pooled cross sectional time-series regression analysis with corrected fixed effect models involving sixteen member countries of the Organisation for Economic Cooperation and Development during the period 1970 to 2001. The PYLL was positively associated with tobacco and alcohol consumption (model 1 and 2) and calories intake (model 2 and 3) while the PYLL was negatively associated with GDP, fruit and vegetable intake (model 2), number of doctors (model 3), coverage rates of health care security, and elderly population rates (model 4). In conclusion, health behaviors related with tobacco, alcohol, and nutrition were significant health determinants for health outcome. Overall analysis results of this study will provide a guidance toward improved macro- and micro-policy development for future health promotion policy in Korea.

• 한국농공학회논문집
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• 제59권5호
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• pp.109-126
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• 2017

Universal soil loss equation (USLE) is used to estimate soil loss solely or employed in any hydrologic models. Since soil erosion has been an issue in South Korea for decades, the Ministry of Environment enacted a law to regulate soil erosion in 2012, which is the Notification of topsoil erosion status. The notification is composed of preliminary and field investigations, the preliminary investigation suggests to use USLE and provides USLE factors. However, the USLE factors provided in the notification was prepared at least 10 years ago, therefore it is limited to reflect recent climate changes. Moreover the current yearly USLE approach does not provide an opportunity to consider seasonal variation of soil erosion in South Korea. A GIS-based model was therefore applied to evaluate the yearly USLE approach in the notification. The GIS-based model employs USLE to estimate soil loss, providing an opportunity to estimate monthly soil loss with monthly USLE factor databases. Soil loss was compared in five watersheds, which were Geumgang, Hangang, Nakdonggang, Seomjingang, and Yeongsangang watersheds. The minimum difference was found at Seomjingang watershed, the yearly potential soil loss were 40.15 Mg/ha/yr by the notification approach and 34.42 Mg/ha/yr by the GIS-based model using monthly approach. And, the maximum difference was found at Nakdonggang watershed, the yearly potential soil loss were 27.01 Mg/ha/yr by the notification approach and 10.67 Mg/ha/yr by the GIS-based model using monthly approach. As a part of the study result, it was found that the potential soil loss can be overestimated in the notification approach.

• 대한청각학회지
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• 제25권3호
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• pp.138-145
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• 2021

Background and Objectives: This study aimed to evaluate the audiologic results after cochlear implantation (CI) in older patients and the degree of improvement in their quality of life (QoL). Subjects and Methods: Patients over 65 years old who underwent CI at implant center in Bozyaka Training and Research Hospital were included in this study (n=54; 34 males and 20 females). The control group was patient over 65 years old with normal hearing (n=54; 34 males and 20 females). We administered three questionnaires [World Health Organization Quality of Life-BREF (WHOQOL-BREF), World Health Organization Quality of Life-OLD (WHOQOL-OLD)], and Geriatric Depression Scale (GDS) to evaluate the QoL, CIrelated effects on activities of daily life, and social activities in all the subjects. Moreover, correlations between speech recognition and the QoL scores were evaluated. The duration of implant use and comorbidities were also examined as potential factors affecting QoL. Results: The patients had remarkable improvements (the mean score of postoperative speech perception 75.7%) in speech perception after CI. The scores for the WHOQOL-OLD and WHOQOL-BREF questionnaire responses were similar in both the study and control groups, except those for a two subdomains (social relations and social participation). The patients with longer-term CI had higher scores than those with short-term CI use. In general, the changes in GDS scores were not significant (p<0.05). Conclusions: The treatment of hearing loss with CI conferred significant improvement in patient's QoL (p<0.01). The evaluation of QoL can provide multidimensional insights into a geriatric patient's progress and, therefore, should be considered by audiologists.

• Journal of Audiology & Otology
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• 제25권3호
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• pp.138-145
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• 2021

Background and Objectives: This study aimed to evaluate the audiologic results after cochlear implantation (CI) in older patients and the degree of improvement in their quality of life (QoL). Subjects and Methods: Patients over 65 years old who underwent CI at implant center in Bozyaka Training and Research Hospital were included in this study (n=54; 34 males and 20 females). The control group was patient over 65 years old with normal hearing (n=54; 34 males and 20 females). We administered three questionnaires [World Health Organization Quality of Life-BREF (WHOQOL-BREF), World Health Organization Quality of Life-OLD (WHOQOL-OLD)], and Geriatric Depression Scale (GDS) to evaluate the QoL, CIrelated effects on activities of daily life, and social activities in all the subjects. Moreover, correlations between speech recognition and the QoL scores were evaluated. The duration of implant use and comorbidities were also examined as potential factors affecting QoL. Results: The patients had remarkable improvements (the mean score of postoperative speech perception 75.7%) in speech perception after CI. The scores for the WHOQOL-OLD and WHOQOL-BREF questionnaire responses were similar in both the study and control groups, except those for a two subdomains (social relations and social participation). The patients with longer-term CI had higher scores than those with short-term CI use. In general, the changes in GDS scores were not significant (p<0.05). Conclusions: The treatment of hearing loss with CI conferred significant improvement in patient's QoL (p<0.01). The evaluation of QoL can provide multidimensional insights into a geriatric patient's progress and, therefore, should be considered by audiologists.

• Biomolecules & Therapeutics
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• 제10권3호
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• pp.137-141
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• 2002

Taurine, amino acid, chemically known as 2-amino ethane sulphonic acid was discovered more than two hundred years ago from ox bile. it is widely distributed in both mammals and nonmammals. It is found in considerably high amount in hUl11an: a normal adult of 70 kgs contains about 70 grams of taurine. Taurine with this much concentration, is involved in almost all life processes. Its deficiency causes several abnormalities in major organs like brain, eye and heart. Taurine-bone interaction is latest addition to its long list of actions. In bone cells, taurine is also found in high concentration. Taurine is found to help in enhancing the bone tissue formation which is evidenced by increased matrix formation and collagen synthesis. Besides stimulating the bone tissue formation, it also inhibits the bone loss through inhibiting the bone resorption and osteoclast formation. Thus, taurine acts as a double agent. In addition to these two major actions of taurine in bone, it also has beneficial effect in wound healing mld bone repair. Taurine possess radioprotective properties, too. As it is a naturally available molecule, it can be used as a preventive agent. Taurine has a potential to replace bisphosphonates which are currently in use for the inhibition of bone loss but this needs in depth study. As taurine is involved in bone formation and inhibition of bone loss, a detailed study can make it a single marker of bone metabolism. All these taurine-bone interaction is a symbol of their deep involvement but still require further extension to make taurine as a choice for tile sound bone health.

• Architectural research
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• 제7권1호
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• pp.49-54
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• 2005

Conventional studies have focused on the reduction in the water-cement ratio, the use of various admixtures, etc., to ensure the durability of reinforced concrete structures against such deterioration factors as carbonation and chloride attack. However, improvement in the concrete quality alone is not considered sufficient or realistic for meeting the recent demand for a service life of over 100 years. This study intends to improve the durability of reinforced concrete structures by improvement in the reinforcing steel, which has remained untouched due to cost problems, through subtle adjustment of the steel components to keep the cost low. As a fundamental study on the performance of Cr-bearing rebars in steel reinforced concrete structures exposed to corrosive environments, The test specimens were made by installing 8 types of rebars in concretes with a chloride ion content of 0.3, 0.6, 1.2, 2.4 and $24kg/m^3$. Corrosion accelerated curing were then conducted with them. The corrosion resistance of Cr-bearing rebars was examined by measuring crack widths, half-cell potential, corrosion area and weight loss after 155 cycles of corrosion-accelerating curing. The results of the study showed that the corrosion resistance increased as the Cr content increased regardless of the content of chloride ions, and that the Cr-bearing rebars with a Cr content of 5% and 9% showed high corrosion resistance in concretes with a chloride ion content of 1.2 and $2.4kg/m^3$, respectively.

• Steel and Composite Structures
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• 제29권4호
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• pp.527-544
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• 2018

The paper presents the study on a change in modal parameters and structural stiffness of cable-stayed Fiberline Bridge made entirely of Glass Fiber Reinforced Polymer (GFRP) composite used for 20 years in the fjord area of Kolding, Denmark. Due to this specific location the bridge structure was subjected to natural aging in harsh environmental conditions. The flexural properties of the pultruded GFRP profiles acquired from the analyzed footbridge in 1997 and 2012 were determined through three-point bending tests. It was found that the Young's modulus increased by approximately 9%. Moreover, the influence of the temperature on the storage and loss modulus of GFRP material acquired from the Fiberline Bridge was studied by the dynamic mechanical analysis. The good thermal stability in potential real temperatures was found. The natural vibration frequencies and mode shapes of the bridge for its original state were evaluated through the application of the Finite Element (FE) method. The initial FE model was created using the real geometrical and material data obtained from both the design data and flexural test results performed in 1997 for the intact composite GFRP material. Full scale experimental investigations of the free-decay response under human jumping for the experimental state were carried out applying accelerometers. Seven natural frequencies, corresponding mode shapes and damping ratios were identified. The numerical and experimental results were compared. Based on the difference in the fundamental natural frequency it was again confirmed that the structural stiffness of the bridge increased by about 9% after 20 years of service life. Data collected from this study were used to validate the assumed FE model. It can be concluded that the updated FE model accurately reproduces the dynamic behavior of the bridge and can be used as a proper baseline model for the long-term monitoring to evaluate the overall structural response under service loads. The obtained results provided a relevant data for the structural health monitoring of all-GFRP bridge.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2131-2136
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• 2016

Background: Cancer is currently one of the main public health problems all over the world and its economic burden is substantial both for health systems and for society as a whole. To inform priorities for cancer control, we here estimated years of potential life lost (YPLL) and productivity losses due to cancer-related premature mortality in Iran from 2006 to 2010. Materials and Methods: The number of cancer deaths by sex and age groups for top ten leading cancers in Iran were obtained from the Ministry of Health and Medical Education. To estimate the YPLL and the cost of productivity loss due to cancer-related premature mortality, the life expectancy method and the human capital approach were used, respectively. Results: There were 138,228 cancer-related deaths in Iran (without Tehran province) of which 76 % (106,954) were attributable to the top 10 ranked cancers. Some 63 % of total cancer-related deaths were of males. The top 10 ranked cancers resulted in 106,766,942 YPLL in total, 64,171,529 (60 %) in males and 42,595,412 (40%) in females. The estimated YPPLL due to top 10 ranked cancers was 58,581,737 during the period studied of which 32,214,524 (54%) was accounted for in males. The total cost of lost productivity caused by premature deaths because of top 10 cancers was 1.68 billion dollars (US$) from 2006 to 2010, ranging from 251 million dollars in 2006 to 283 million dollars in 2010. Conclusions: This study showed that the economic burden of premature mortality attributable to cancer is significant for Iranian society. The findings provide useful information about the economic impact of cancer for health system policy/decision makers and should facilitate planning of preventive intervention and effective resource allocation.

• International Journal of Concrete Structures and Materials
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• 제2권2호
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• pp.137-143
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• 2008

In recent years, much research work has been performed on durability design and long-term performance of concrete structures in marine environments. In particular, the development of new procedures for probability-based durability design has been shown to provide a more realistic basis for the analysis. This approach has been successfully applied to several new concrete structures, where requirements for a more controlled durability and service life have been specified. For reinforced concrete structures in a marine environment, it is commonly assumed that the dominant degradation mechanism is the corrosion of the reinforcement due to the presence of chlorides. The design approach is based on the verification of durability limit states, examples of which are: depassivation of reinforcement, cracking and spalling due to corrosion, and collapse due to cross section loss of reinforcement. With this design approach the probability of failure can be determined as a function of time. In the present paper, a probability-based durability performance analysis is used in order to demonstrate the importance of the durability design approach of concrete structures in marine environments. In addition, the sensitivity of the various durability parameters affecting and controlling the durability of concrete structures in a marine environment is studied. Results show that the potential of this approach to assist durability design decisions making process is great. Based the crucial information generated, it is possible to prolong the service life of structures while simultaneously optimizing the final design solution.