• Title/Summary/Keyword: ppc

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Subtotal Resection of the Giant Paraprostatic Cyst with Omentalization in a Dog: A Case Report

  • Youngrok Song;Youngsoo Hong;Solji Choi;Woojin Song;Hyunjung Park;Joo-Myoung Lee;Jungha Lee;Jongtae Cheong
    • Journal of Veterinary Clinics
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    • v.40 no.3
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    • pp.230-237
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    • 2023
  • A 6-year-old intact male Cane Corso dog weighing 40 kg with a 2-month history of dysuria, dyschezia, anorexia, intermittent panting, and penile discharge presented to the Veterinary Medical Teaching Hospital of Jeju National University. Examination revealed a giant paraprostatic cyst (PPC) that occupied a large part of the abdomen and caused displacement of organs. Radiography, ultrasound, and computed tomography (CT) scans confirmed that the PPC had spread to the pelvic regions. Subtotal resection was performed, leaving two sites with PPC remnants. One site was the prostate gland, which communicated with, and adhered to, the PPC; the other site was the pelvic region, where the PPC had spread. The reason for leaving two remnants was that an anatomical approach for complete resection was difficult, and to avoid complications associated with prostatic urethra damage. Routine omentalization and castration were performed. Partial cystectomy was performed because of the presence of a diverticulum-like lesion in the ventral part of the urinary bladder. The patient's clinical symptoms, including dysuria, completely resolved, and voluntary urination was possible 1 day post-operatively. Histopathological examination revealed osseous metaplasia of the PPC. The patient was well-managed and had no post-operative complications or recurrence until day 180 of follow-up.

Propofol protects against oxidative-stress-induced COS-7 cell apoptosis by inducing autophagy

  • Yoon, Ji-Young;Baek, Chul-Woo;Kim, Eun-Jung;Park, Bong-Soo;Yu, Su-Bin;Yoon, Ji-Uk;Kim, Eok-Nyun
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.17 no.1
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    • pp.37-46
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    • 2017
  • Background: In oxidative stress, reactive oxygen species (ROS) production contributes to cellular dysfunction and initiates the apoptotic cascade. Autophagy is considered the mechanism that decreases ROS concentration and oxidative damage. Propofol shows antioxidant properties, but the mechanisms underlying the effect of propofol preconditioning (PPC) on oxidative injury remain unclear. Therefore, we investigated whether PPC protects against cell damage from hydrogen peroxide ($H_2O_2$)-induced oxidative stress and influences cellular autophagy. Method: COS-7 cells were randomly divided into the following groups: control, cells were incubated in normoxia (5% $CO_2$, 21% $O_2$, and 74% $N_2$) for 24 h without propofol; $H_2O_2$, cells were exposed to $H_2O_2$ ($400{\mu}M$) for 2 h; $PPC+H_2O_2$, cells pretreated with propofol were exposed to $H_2O_2$; and 3-methyladenine $(3-MA)+PPC+H_2O_2$, cells pretreated with 3-MA (1 mM) for 1 h and propofol were exposed to $H_2O_2$. Cell viability was determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide thiazolyl blue (MTT) reduction. Apoptosis was determined using Hoechst 33342 staining and fluorescence microscopy. The relationship between PPC and autophagy was detected using western blot analysis. Results: Cell viability decreased more significantly in the $H_2O_2$ group than in the control group, but it was improved by PPC ($100{\mu}M$). Pretreatment with propofol effectively decreased $H_2O_2$-induced COS-7 cell apoptosis. However, pretreatment with 3-MA inhibited the protective effect of propofol during apoptosis. Western blot analysis showed that the level of autophagy-related proteins was higher in the $PPC+H_2O_2$ group than that in the $H_2O_2$ group. Conclusion: PPC has a protective effect on $H_2O_2$-induced COS-7 cell apoptosis, which is mediated by autophagy activation.

How to Implement Quality Pediatric Palliative Care Services in South Korea: Lessons from Other Countries (한국 소아청소년 완화의료의 발전 방안 제언: 국외 제공체계의 시사점을 중심으로)

  • Kim, Cho Hee;Kim, Min Sun;Shin, Hee Young;Song, In Gyu;Moon, Yi Ji
    • Journal of Hospice and Palliative Care
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    • v.22 no.3
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    • pp.105-116
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    • 2019
  • Purpose: Pediatric palliative care (PPC) is emphasized as standard care for children with life-limiting conditions to improve the quality of life. In Korea, a government-funded pilot program was launched only in July 2018. Given that, this study examined various PPC delivery models in other countries to refine the PPC model in Korea. Methods: Target countries were selected based on the level of PPC provided there: the United Kingdom, the United States, Japan, and Singapore. Relevant literature, websites, and consultations from specialists were analyzed by the integrative review method. Literature search was conducted in PubMed, Google, and Google Scholar, focusing publications since 1990, and on-site visits were conducted to ensure reliability. Analysis was performed on each country's process to develop its PPC scheme, policy, funding model, target population, delivery system, and quality assurance. Results: In the United Kingdom, community-based free-standing facilities work closely with primary care and exchange advice and referrals with specialized PPC consult teams of children's hospitals. In the United States, hospital-based specialized PPC consult teams set up networks with hospice agencies and home healthcare agencies and provide PPC by designating care coordinators. In Japan, palliative care is provided through several services such as palliative care for cancer patients, home care for technology-dependent patients, other support services for children with disabilities and/or chronic conditions. In Singapore, a home-based PPC association plays a pivotal role in providing PPC by taking advantage of geographic accessibility and cooperating with tertiary hospitals. Conclusion: It is warranted to identify unmet needs and establish an appropriate PPD model to provide need-based individualized care and optimize PPC in South Korea.

PEO/PPC based Composite Solid Electrolyte for Room Temperature Operable All Solid-State Batteries (상온에서 작동되는 전고체전지 용 PEO/PPC 기반의 복합 고체 전해질)

  • Shin, Sohyeon;Kim, Sunghoon;Cho, Younghyun;Ahn, Wook
    • Journal of the Korean Electrochemical Society
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    • v.25 no.3
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    • pp.105-112
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    • 2022
  • For the commercialization of all-solid-state batteries, it is essential to develop a solid electrolyte that can be operable at room temperature, and it is necessary to manufacture all-solid-state batteries by adopting materials with high ionic conductivity. Therefore, in order to increase the ionic conductivity of the existing oxide-based solid, Li7La3Zr2O12 (LLZO) doped with heterogeneous elements was used as a filler material (Al and Nb-LLZO). An electrolyte with garnet-type inorganic filler doped was prepared. The binary metal element and the polymer mixture of poly(ethylene oxide)/poly(propylene carbonate) (PEO/PPC) (1:1) are uniformly manufactured at a ratio of 1:2.4, The electrochemical performance was tested at room temperature and 60 ℃ to verify room temperature operability of the all-solid-state battery. The prepared composite electrolyte shows improved ionic conductivity derived from co-doping of the binary elements, and the PPC helps to improve the ionic conductivity, thereby increasing the capacity of all-solid-state batteries at room temperature as well as 60 ℃. It was confirmed that the capacity retention rate was improved.

A Study on the Influence Factors on Crack Properties of CFRD Face Slab Concrete (CFRD 차수벽 콘크리트의 균열 특성에 미치는 각종 영향요인에 관한 연구)

  • 최세진;임정열;김완영;김무한
    • Journal of the Korea Concrete Institute
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    • v.12 no.6
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    • pp.109-117
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    • 2000
  • CFRD(Concrete Faced Rockfill Dam) face slab concrete has a much capability to occur crack due to drying shrinkage, plastic shrinkage and bad compaction etc. Because of these cracks of concrete induce structural problem and decrease durability of dam, it is need to reduce crack of face slab concrete. This is an experimental study to analyze the influence factors on crack properties of CFRD face slab concrete. For this purpose, various mix proportion of CFRD face slab concrete and concrete using PPF(polypropylene fiber0 and fly ash was selected. And tests for drying shrinkage, bonding strength, water permeability and plastic shrinkage were performed, and then CFRD D and PPC of those mix proportion were placed in CFRD field. According to test results, it was found that the bonding strength of C1(compact sufficiently) was higher about 10~20% than that of C2(compact insufficiently). And the engineering properties of PPC(concrete using PPF) and FAC(concrete using fly ash) were better than those of the others ; the permeability of PPC and FAC after 8 weeks curing was little lower than that of CFRD D, and plastic shrinkage crack of PPC and FAC was lower 40~60% than crack of CFRD D.

Efficient Productivity Evaluation System in Construction Site (건설현장 생산성 측정의 효율적 방안 제시)

  • Jang, Hyo-Won;Kim, Soo-Yong;Kim, Dae-Young
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2007.11a
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    • pp.666-669
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    • 2007
  • 건설 공사에 있어서 생산성은 중요한 의미를 가지고 있다. 하지만 국내 건설현장에서의 샌산성에 대한 인식은 상당히 낮은 것으로 보이며, 건설현장에서의 생산성에 대한 인식변화 및 활성화를 위한 토대를 마련하는 연구는 드물었다고 판단된다. 기존의 생산성 측정에는 많은 방법들이 사용되어지고 있으며, 이러한 측정 기법들은 생산성 측정에 있어서 결과만을 모니터링하고 보다 나은 결과물을 획득하는데 그 목적이 있어왔다. 하지만, 해외의 경우 건설 생산성의 초기투입단계에서의 관리와 노력을 통해 생산성을 향상시키고자 하고 있다. 따라서 본 연구에서는 린 건설에 관련하여 기존의 생산성 측정보다 쉽게 생산성을 측정할수 있고 빠른 피드백을 얻을 수 있는 percent plan complete(PPC)의 기법을 적용한 새로운 생산성 관리가 어떠한 프로세스로 이루어지고 있는지 분석하고 국내 건설 현장의 새로운 생산성 관리 시스템 구축의 기반을 마련코자 한다. PPC는 계획되어진 작업계획의 신뢰성과 생산성을 측정 가능토록 해주며, 린 시스템의 적용이 필주적으로 수반되어야 한다. PPC 측정 후 작업이 실패되었을 경우 그 이유를 파악하고 원인 분석이 이루어져야 한다. 그렇게 된다면 어떤 공정에 대한 결과를 평가할 수 있고 그 과정에서 미래에 발생할수 있는 작업 실패를 예방할 수 있다.

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Pleuroperitoneal communication-associated pleuritis as an uncommon cause of fever of unknown origin in a child on peritoneal dialysis: a case report

  • Juhee Park;Heeyon Yoon;Jiwon Jung;Jina Lee;Joo Hoon Lee
    • Childhood Kidney Diseases
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    • v.27 no.1
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    • pp.46-53
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    • 2023
  • Pleuroperitoneal communication (PPC) is a rare mechanical complication of peritoneal dialysis (PD), which causes dialysate to move from the peritoneal cavity to the pleural cavity, resulting in pleural effusion. Typically, PPC is discovered through pleural effusion in PD patients who are not in volume overload status. A unique characteristic of the pleural effusion caused by PPC is that it is not resolved by increasing ultrafiltration by dialysis. In this report, we present a 7-year-old girl with PD after birth with the history of various infectious PD-related complications, presenting with fever ongoing for 6 months. PPC-associated pleuritis was suspected as the cause of fever, which eventually developed after long-term PD and induced complicated pleural effusion, lung inflammation, and prolonged fever for 6 months.

Needs for Pediatric Palliative Care among Parents of Children with Complex Chronic Conditions (복합만성질환을 가진 자녀를 둔 부모의 소아청소년 완화의료 요구도)

  • Yun, Hyeseon;Hwang, Ae Ran;Kim, Sanghee;Choi, Eun Kyoung
    • Child Health Nursing Research
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    • v.24 no.4
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    • pp.527-536
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    • 2018
  • Purpose: The purpose of this study was to investigate the needs for pediatric palliative care (PPC) among parents of children with complex chronic conditions (CCCs) and to investigate differences in the needs for PPC according to their general characteristics. Methods: A cross-sectional survey was conducted between March 28 and May 18, 2018. Parents (N=96) who had a child under 18 years with a CCC were recruited. Data were analyzed using descriptive statistics, independent t-test, and one-way ANOVA. Results: The overall average need for PPC was $3.58{\pm}0.33$ out of 4.00. In terms of care for the subjects' children, the highest need was physical care, followed by psychosocial and spiritual care. In the sub-dimensions, preservation of physical function received the highest score. Of the items, the highest need was for seizure control. In terms of care for the subjects themselves, the highest need was for psychosocial care, followed by bereavement and spiritual care. In the sub-dimensions, communication received the highest score. Of the items, the highest need was for smooth communication with medical staff. Differences in needs for PPC according to participants' general characteristics were not statistically significant. Conclusion: Medical staff should provide PPC according to the priorities of parents' perceived needs.

Playback Quantity-based Proxy Caching Scheme for Continuous Media Data (재생량에 기반한 연속미디어 데이터 프록시 캐슁 기법)

  • Hong, Hyeon-Ok;Im, Eun-Ji;Jeong, Gi-Dong
    • The KIPS Transactions:PartB
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    • v.9B no.3
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    • pp.303-310
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    • 2002
  • In this paper, we propose a proxy caching scheme that stores a portion of a continuous media object or an entire object on the Internet. The proxy stores the initial fraction of a continuous media object and determines the optimal size of the initial fraction of the continuous media object to be cached based on the object popularity. Under the proposed scheme, the initial latency of most clients and the data transferred from a remote server can be reduced and limited cache storage space can be utilized efficiently. Considering the characteristics of continuous media, we also propose the novel popularity for the continuous media objects based on the amount of the data of each object played by the clients. Finally, we have performed trace-driven simulations to evaluate our caching scheme and the popularity for the continuous media objects. Through these simulations, we have verified that our caching scheme, PPC outperforms other well-known caching schemes in terms of BHR, DSR and replacement and that popularity for the continuous media objects based on the amount of the playback data can enhance the performance of caching scheme.