• Journal of Sasang Constitutional Medicine
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• v.35 no.4
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• pp.65-71
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• 2023

Objectives This case study aimed to report the improvement of stress-induced generalized primary hyperhidrosis of Soyangin patient. Methods Soyangin patient suffering from daylong generalized primary hyperhidrosis was treated with acupuncture, psychological counseling, and herbal medicine. The severity of hyperhidrosis was measured using Visual Analog Scale (VAS). Results & Conclusions After treatment with Tae-Geuk acupuncture, Dojeokganggi-tang, and psychological counseling, the VAS score of hyperhidrosis was reduced from 10 to 2 during three days of admission. Herbal medicine was prescribed for 30 more days after discharge. The relieved state was maintained when monitored after two months. This case report proposes the potential of Sasang constitutional medicine for stress-induced generalized primary hyperhidrosis.

• The Journal of Internal Korean Medicine
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• v.28 no.3
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• pp.597-607
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• 2007

Backgrounds and Objectives: Primary hyperhidrosis deeply affect a patient's quality of life, resulting in impairments of daily activities, social interactions and occupational activities. The objectives of the study were to assess quality of life(QOL) in patients with primary hyperhidrosis before and after treatment with oriental medicine. Methods : Between December 2006 and July 2007, 26 patients underwent oriental medicine treatment. which consisted of herb medicine. acupuncture and iontophosis (if palmar/plantar hyperhidrosis) treatment. QOL questionnaires comprised of dermatology life quality index (DLQI) and visual analogue scale (VAS) were employed before and after treatment Results : All 26 patients were evaluated. The treatment controlled primary hyperhidrosis in 84.6% of cases. The mean of DLQI score before treatment was 16.65 after treatment mean DLQI score was 8.18. The mean of VAS before treatment was 91.35 after treatment mean VAS was 49.92. QOL in patients with primary hyperhidrosis significantly improved after oriental medicine treatment. The improvements in QOL were similar in patientswith palmar/plantar, head, and systemic hyperhidrosis. Conclusions : Oriental medicine treatment leads to significantly improved QOL in patients with primary hyperhidrosis. Further studies are needed to evaluate the objective efficacy in patients with primary hyperhidrosis before and after oriental medicine treatment.

• The Korean Journal of Pain
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• v.25 no.1
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• pp.28-32
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• 2012

Background: Primary hyperhidrosis is a disorder of excessive sweating, which shares several features with anxiety disorders and has a negative impact on a patient's quality of life. Oral glycopyrrolate is one of the treatments available. There are a few published studies on the use of glycopyrrolate given orally in the treatment of hyperhidrosis. Methods: Thies is study was a review of case notes in a series of 36 patients with primary hyperhidrosis. We made a comparison between the Keller's scale score of a pre-glycopyrrolate medication group and the Keller's scale score f a post-glycopyrrolate medication group. The Milanez de Campos score, Short Form_36 (SF-36) score, Beck Depression Inventory (BDI) score, Beck Anxiety Inventory (BAI) score, and autonomic nervous system (ANS) scale score were also compared between the two groups. Results: In the post-glycopyrrolate medication group, there were declines in Keller's scale, and Milanez de Campos scale score and BAI score (P < 0.001). In addition, there were increases in SF_36 score in the post-glycopyrrolate medication group (P = 0.03) However, no changes were seen in, BDI score and ANS score in the post-glycopyrrolate medication group (P < 0.001). Conclusions: Glycopyrrolate is an effective initial method of treating primary hyperhidrosis that, reduces anxiety and improve patients' quality of life.

• The Journal of Pediatrics of Korean Medicine
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• v.36 no.3
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• pp.75-86
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• 2022

Objectives The purpose of the study is to review the trend of clinical trials conducted in China with oral herbal medicine treatment on childhood primary hyperhidrosis. Methods We searched the randomized controlled trials (RCTs) with oral herbal medicine treatment on childhood primary hyperhidrosis from the China National Knowledge Infrastructure (CNKI). The demographic data, duration of illness, intervention, treatment period, outcome and composition of herbal medicine were analyzed for this study. Results A total of five RCTs were selected and analyzed. The effectiveness of the oral administration of herbal medicines on childhood primary hyperhidrosis was found to be significant. In one study, there was no statistical difference between the treatment group and the control group when curative effect was evaluated two weeks after the intervention; however, the treatment group showed a statistically higher curative effect than the control group at one and two months after intervention, and also one month after the intervention was terminated. Conclusions Oral herbal medicine has been shown to be an effective treatment for childhood primary hyperhidrosis, and it takes at least one month for the administered oral herbal medicines to take effect. However, further well-designed large-scale randomized controlled trials are needed to confirm the efficacy and safety of oral herbal medicines in childhood primary hyperhidrosis.

• The Journal of Internal Korean Medicine
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• v.33 no.3
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• pp.327-337
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• 2012

Objectives : The purpose of this study was to report the clinical effect of short- term admission program on primary palmar/plantar hyperhidrosis in children and adolescents. Methods : Between January 2011 and January 2012, a total of 11 patients with clinical diagnosis of primary palmar/plantar hyperhidrosis were treated with hospitalization which consisted of iontophoresis, electro-acupuncture, herbal medicine, topical therapy and physical therapy. The effects were evaluated as quality of life with dermatology life quality index (DLQI), severity of discomfort using visual analogue scale (VAS), and the patients' subjective satisfaction. We analyzed the patients' improvement before and after admission treatment, as well as six month later. Results : After treatment, the 11 patients' quality of life and severity of discomfort improved significantly. They also were satisfied with oriental treatments for hyper hidrosis. Six months later, 6 of 11 patients had visited the hyperhidrosis clinic. Their symptoms had improved and remained stable. Conclusions : The short-term admission program is effective on primary palmar/plantar hyperhidrosis. Further studies with a larger number of cases will be needed in the future.

• The Journal of Korean Medicine
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• v.33 no.4
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• pp.37-41
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• 2012

Objectives: This study was aimed to establish the clinical features of the patients suffering from hyperhidrosis, who are willing to visit Oriental clinics. Methods: Forty-six patients with primary hyperhidrosis were enrolled in this study classification, body part of perspiration and its severity, and constitutional differentiation were analyzed. Results: 85.1% of patients were 10 to 39 years old. The body part most complained of hyperhidrosis was the hands and feet at 50%. The portion of Teaeumin, Soumin, and Soyangin was 56.6% 21.1%, and 21.7% respectively. Soumin specifically showed a higher frequency of palmar and plantar hyperhidrosis as 90%. The average score of symptoms was $5.1{\pm}1.7$ by a 10-point self- reporting numeric rating scale (NRS). No statistical difference of NRS score was observed regarding gender, Sasang classification, or hyperhidrosis region. Conclusions: This study provides an overview of hyperhidrosis patients visiting an Oriental clinic, and will be helpful in establishing a strategy for the Korean medicine (KM)-based therapeutic development.

• Annals of Clinical Neurophysiology
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• v.14 no.1
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• pp.12-19
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• 2012

Thermoregulatory sweat is principal mean for homeostasis of temperature. Sweat glands have eccrine gland, apocrine gland, and apoeccrine glands. Disorders of sweating are manifested by excess (hyperhidrosis) or deficit (hypohidrosis, anhidrosis) of sweat. Hyperhidrosis can be defined as excessive sweating beyond a level required to maintain normal body temperature. The sweating can be generalized or localized (axilla, palms, soles, palmar-plantar, perineal). Usually hypohidrosis or anhidrosis may be more serious than hyperhidrosis. Hyperhidrosis is usually benign, but interferes with one's daily activities. First step for diagnostic approach for sweating disorders might be dividing them into localized or generalized, and primary or secondary forms. Treatement for hyperhidrosis include topical agents, botulinum toxin A injections, systemic anticholinergics, and sympathectomy.

• The Korean Journal of Pain
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• v.18 no.1
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• pp.92-95
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• 2005

Primary hyperhidrosis, a disorder of unknown etiology, is characterized by excessive uncontrollable sweating, most often of the palm surface of the hands, armpits, groin and feet. To decrease the symptoms of hyperhidrosis, drug therapy, iontophoresis, excision of axillary sweat glands and thoracoscopic sympathectomy have been attempted. A lumbar sympathectomy is one of the available choices for the treatment hyperhidrosis of the lower extremities. A 28-year old female patient presented with excessive sweating of her hands and feet. For the treatment of her foot hyperhidrosis, a bipolar radiofrequency ablation system was used to ablate the lumbar sympathetic ganglion, with a successful result. This modality will receive greater attention as an available alternative to lumbar sympathetic neurolysis.

• The Journal of Internal Korean Medicine
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• v.26 no.4
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• pp.897-903
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• 2005

Excessive sweating, especially hyperhidrosis of palms, solies and axillae, is a distressing problem in the making of a person's social life. Most important in cases of localized hyperhidrosis is the emotional factor. Thoracoscopic sympathectomy is an effective method, but this may result in a postoperatively compensatory hyperhidrosis of facial anhidrosis in the treatment of localized hyperhidrosis. One case of excessive sweating of palms, solies and axillare was observed and treated with the emotional factor taken as primary. This patient was treated with Bokryungbosimtang-gamibang and improvement was seen.

• Journal of Sasang Constitutional Medicine
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• v.26 no.4
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• pp.379-388
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• 2014

Objectives The aim of this study was to report significant improvement of hyperhidrosis after treatment with Hyungbangsabaek-san (荊防瀉白散), in a Soyangin Mangeum Symptomatic pattern Patient. Methods The patients were diagnosed with Soyang Sin-Yeol Du-Tong Mang-Eum Symptomatology(身熱頭痛亡陰證) and treated with Hyungbangsabaek-san(荊防瀉白散). The primary outcome measure for this study were sweat using a questionnaire with visual analogue scale(VAS). Secondary outcome assessment included change of odinary symptoms such as patient's sleep, feces and digestion. Results The symptoms of hyperhidrosis disappeared by the end of the accure period without side effect. Original symptoms were also changed. Conclusions This result show Hyungbangsabaek-san(荊防瀉白散) can be used to treat hyperhidrosis in a Soyangin Heat-related diarrhea accompanied by headache Mangeum(身熱頭痛亡陰) symptomatic pattern patient. Meaning and process of hyperhidrosis are different according to Sasang Constitutions.