• Title/Summary/Keyword: risk factor

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Study on Relationship between the Bone Mineral Density and Cardiovascular Risk Factor in the Postmenopausal Women (폐경 후 여성에서 골밀도와 심혈관위험인자의 관련성에 대한 연구)

  • Han, Beom-Hee;Jung, Hong-Ryang
    • The Journal of the Korea Contents Association
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    • v.9 no.10
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    • pp.176-185
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    • 2009
  • The study surveyed 653 people who have been blood pressure measuring and body feature in postmenopausal women received BMD test. The statistical analysis was done using the SPSS 12.0 for windows and the study using comparison analyzed at ANOVA, X 2. linear regression analysis, the following conclusions were made. As a result of analyzing the relationship between BMD and Cardiovascular Risk Factor were found to be a positive significant component(p<0.001) height, weight, BMI. After the analyses of the age, systolic blood pressure, diastolic blood pressure, total cholesterol, high density lipoprotein cholesterol, triglyceride and glucose were shown to be a negative significant component(p<0.001). Weight was the one that was mostly affected BMD(18.7%). As a result of analyzing the relationship between BMD and Cardiovascular Risk Factor had a significant component at all. According to the problem with osteoporosis in women is becoming a major issue in society. The study is considered to be tried to make phased and, better organized to establish preventive strategies and warranted causes of osteoporosis.

The Relationship between Risk Factors for Cardiovascular Disease and Levels of Plasma Total Homocysteine, Folate and Vitamin {TEX}$B_{12}${/TEX} in Koreans

  • Lim, Hyeon-Sook;Heo, Young-Ran
    • Preventive Nutrition and Food Science
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    • v.6 no.1
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    • pp.73-78
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    • 2001
  • The elevation of total plasmahomocysteine is now an established risk factor for cardiovascular disease. Plasma folate and vitamin {TEX}$B_{12}${/TEX} influence Hcy metabolism as cofactors. In this study, we studied the relationship of major risk factors for cardovascular disease, including advanced age, male gender, obesity, hypertension, hyperglycemia, and dislipidemia and plasma homocyteine, folate and vitamin {TEX}$B_{12}${/TEX} levels in Koreans. A total of 195 adult Koreans participated. The subjects were divided into three groups according to how many major conventional risk factors of cardiovascular disease they had: no risk, low risk (1~3 risk factors) and high risk (>3 risk factors) groups. As the number of risk factors increased, the plasma homocysteine levels significantly increase, while the plasma folate levels significantly decreased. The plasma homocysteine levels re higher in males than in females. The subjects with hyperglycemia had higher plasma homocysteine levels than the subjects without the risk factor. Also the subjects with dislipidemia had higher plasma homocysteine levels than the subjects without the risk factor. The plasma folate and vitamin {TEX}$B_{12}${/TEX} levels were significantly lower in males tan females. However, there were no significant differences in plasma folate and vitamin {TEX}$B_{12}${/TEX} levels between the subjects with or without other risk factors. These results indicate that plasma homocysteine levels were positively related with risk factors for cardiovascular disease and plasma folate levels were negatively related with the risk factors for cardiovascular disease. Also, we conclude that plasmahomocysteine levels might be related to the combination of risk factors, rather than an individual risk factor.

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Sasang Constitution may act as a Risk Factor for Hypertension and Pre-hypertension (고혈압 및 전기고혈압 위험요인으로서의 사상체질)

  • Jang, Eunsu;Jeong, Kyoung Sik;Lim, Sueun;Kim, Yunyoung
    • Journal of Sasang Constitutional Medicine
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    • v.34 no.1
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    • pp.37-45
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    • 2022
  • Objectives The purpose of this study was to reveal that Sasang constitution(SC) was associated with hypertension and pre-hypertension and could be a risk factor. Methods We introduced this study to educational personnel in D university in Daejeon, and 275 subjects joined this study. The SC classification was conducted with KS 15 questionnaire. The subjected measured the blood pressure with Jawon medical device automatically after 10 minute rest. The hypertension and pre-hypertension was classified by the guide of the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. The frequency analysis and T-test was used in general characteristics, and chi-square test was also used between SC and pre-hypertension and hypertension. Logistic regression was used to calculate the odds ratios (ORs) and 95% confidence interval (95% CI) for pre-hypertension and hypertension. Results The number of Taeeumin(TE), Soeumin(SE), and Soyangin(SY) was 142, 71, and 61 respectively. There was significantly different in systolic and diastolic blood pressure among SC types(p<.001). The distribution of the normal group, pre-hypertension and hypertension group by SC types was significantly different (p<.001). The ORs of TE was significantly increased (ORs 4.039, 95% CI=2.019-8.082 in pre-hypertension and ORs 4.235, 95% CI=1.581-11.348 in hypertension) compared with SE(p<.001), and after adjusting gender and smoking habit, it was still significantly different(p<.001). Conclusions It is possible that SC, especially TE could be a risk factor both pre-hypertension and hypertension.

An Analysis on the Probability Costs Variation Ranges of the Cost Items from the Risk Factor Model for Construction Phase of Overseas Gas Plant Projects (해외 가스 플랜트 시공단계의 위험요인 모델을 통한 비용 항목별 확률적 비용 변동범위 분석)

  • Kang, Hyun-Wook;Won, Yoo-Man;Kang, Min-Ku;Kim, Yong-Su
    • Journal of the Architectural Institute of Korea Structure & Construction
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    • v.28 no.1
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    • pp.191-198
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    • 2012
  • The purpose of this study is to analyze the Probability Costs variation ranges of the cost items from the risk factor model for construction phase of overseas gas plant projects. For this purpose, the risk factors were first examined through literature reviews and the main risk factors were selected according to its level of significance and occurrence rate through interviews with professionals. The percentage changes in the total construction cost for each main risk factors were computed and applied to the example case from the past. Monte-Carlo Simulation was employed on these results to analyze the probabilistic variation range. The results obtained from the above procedure are as follows. First, there were a total of ten risk factors including the schedule changes for materials procurement, the prolonged construction schedule, the modifications in design, and the changes in materials costs. Second, the variation ranges of the cost items affected by the above risk factors are as follows. The labor costs varied from 7,702 to 7,815 million KRW; the subcontracting costs varied from 83,688 to 85,495 million KRW; the contingency allowances varied from 7,330 to 7,468 million KRW.

Risk factor for pituitary dysfunction in children and adolescents with Rathke's cleft cysts

  • Lim, Han-Hyuk;Yang, Sei-Won
    • Clinical and Experimental Pediatrics
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    • v.53 no.7
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    • pp.759-765
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    • 2010
  • Purpose: This study evaluated the clinical manifestations of and risk factors for pituitary insufficiency in children and adolescents with Rathke's cleft cysts. Methods: Forty-four patients with Rathke's cleft cysts younger than 19 years who visited Seoul National University Children's Hospital between January 1995 and September 2009 were enrolled. Rathke's cleft cysts were confirmed histologically through an operation in 15 patients and by brain magnetic resonance imaging (MRI) in 29 patients. The clinical, hormonal, and imaging features were reviewed retrospectively. Results: The clinical presentation of symptomatic patients was as follows: headache (65%), endocrinopathy (61%), and visual disturbance (19%). Endocrinopathy included central precocious puberty (18%), diabetes insipidus (14%), general weakness (11%), and decreased growth velocity (7%). After surgery, hyperprolactinemia resolved in all patients, but growth hormone insufficiency, hypothyroidism, and diabetes insipidus did not improve. Pituitary insufficiency except gonadotropin abnormality correlated significantly with severe headache, visual disturbance, general weakness, and cystic size. Suprasellar extension of cysts and high signals in the T2-weighted image on brain MRI were related to hypothyroidism, hypocortisolism, and diabetes insipidus. Multivariable linear regression analysis showed that only general weakness was a risk factor for pituitary insufficiency ($R^2$=0.549). Conclusion: General weakness is a risk factor for pituitary insufficiency in patients with Rathke's cleft cysts. When a patient with a Rathke's cleft cyst complains of general weakness, the clinician should evaluate pituitary function and consider surgical treatment.

Development of the Structural Model of Adolescent's Risk Behavior (청소년의 위험행동 구조모형 구축)

  • Park, Hyun-Sook;Jung, Sun-Young
    • Journal of Korean Academy of Nursing
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    • v.41 no.3
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    • pp.364-373
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    • 2011
  • Purpose: In this study the fitness of a path model for the relationship among biological risk disposition, sociocultural risk factors, self-control, parent-adolescent communication, and risk behavior in adolescents was examined. Methods: The participants were 387 adolescents. The data were analyzed with the PASW 18.0 and AMOS 18.0 programs. Results: Sociocultural risk factors, self-control, and parent-adolescent communication showed a direct effect on risk behavior for adolescents, while biological risk disposition and sociocultural risk factor showed an indirect effect on risk behavior for adolescents. The modified path model of adolescents' risk behavior was showed a good fit with the model ($X^2$/df=2.37, GFI=.95, AGFI=.92, RMSEA=.06 [.05

Health Behavior Factors Related Type 2 Diabetes by Obesity for Health Promotion in Adolescents (청소년 건강증진교육을 위한 비만여부에 따른 당뇨병 관련 건강행태)

  • Paek, Kyung-Won;Chun, Ki-Hong
    • Journal of the Korean Society of School Health
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    • v.21 no.2
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    • pp.61-73
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    • 2008
  • Purpose: Several health behavior factors affect the incidence of type 2 diabetes. Especially, obesity, which causes insulin resistance, is the most important determinant of diabetes. Therefore, we expect the risk factors associated with insulin resistance and type 2 diabetes are affected by obesity and, additionally, the related factors with diabetes caused by obesity can be controlled. Methods: This study used data collected from the 2001 Korea National Health and Nutrition Examination Survey (KNHANES). A stratified multistage probability sampling method was applied and the final sample included 5,500 subjects over 30 years old who had completed necessary health examinations and health behaviors survey. Results: The risk factors associated with type 2 diabetes are affected by obesity. According to logistic regression model stratified by body mass index (BMI) and sex, abdominal obesity and age were the significant risk factors of diabetes regardless of sex and BMI. However, drinking, smoking, total energy consumption, and protein consumption were risk factors for women with normal BMI, while carbohydrate consumption was a risk factor for man with normal BMI. Sleeping hours affected diabetes for women with obesity and fiber consumption was a risk factor for both women and men with obesity. In addition, statistically the family history of diabetes was a significant risk factor only in the group with normal weight, not in the group with obesity. Conclusion: The study results will provide information for implementing a regional initiative of type 2 diabetes prevention by BMI.

Factors Associated with Unplanned Hospital Readmission (서울시 소재 한 대학병원 퇴원환자의 재입원 관련요인)

  • Lee, Eun-Whan;Yu, Seung-Hum;Lee, Hae-Jong;Kim, Suk-Il
    • Korea Journal of Hospital Management
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    • v.15 no.4
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    • pp.125-142
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    • 2010
  • Objective : To determine demographic, clinical, health care utilization factors predicting unplanned readmission(within 28 days) to the hospital. Methods : A case-control study was conducted from January to December 2009. Multiple logistic regression was used to examine risk factors for readmission. 180 patients who had been readmitted within 28 days and 1,784 controls were recruited from an university hospital in Seoul. Results : Six risk factors associated with readmission risk were identified and include mail sex, medical service rather than surgical service, number of comorbid diseases, type of patient's room, lenth of stay, number of admissions in the prior 12 months. Conclusions : One of the association with readmission risk identified was the number of hospital admissions in the previous year. This factor may be the only risk factor necessary for assessing prior risk and has the additional advantage of being easily accessible from computerized medical records without requiring other medical record review. This risk factor may be useful in identifying a group at high readmission risk, which could be targeted in intervention studies. Multiple risk factors intervention approach should be considered in designing future prevention strategies.

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A comparison of Multilayer Perceptron with Logistic Regression for the Risk Factor Analysis of Type 2 Diabetes Mellitus (제2형 당뇨병의 위험인자 분석을 위한 다층 퍼셉트론과 로지스틱 회귀 모델의 비교)

  • 서혜숙;최진욱;이홍규
    • Journal of Biomedical Engineering Research
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    • v.22 no.4
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    • pp.369-375
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    • 2001
  • The statistical regression model is one of the most frequently used clinical analysis methods. It has basic assumption of linearity, additivity and normal distribution of data. However, most of biological data in medical field are nonlinear and unevenly distributed. To overcome the discrepancy between the basic assumption of statistical model and actual biological data, we propose a new analytical method based on artificial neural network. The newly developed multilayer perceptron(MLP) is trained with 120 data set (60 normal, 60 patient). On applying test data, it shows the discrimination power of 0.76. The diabetic risk factors were also identified from the MLP neural network model and the logistic regression model. The signigicant risk factors identified by MLP model were post prandial glucose level(PP2), sex(male), fasting blood sugar(FBS) level, age, SBP, AC and WHR. Those from the regression model are sex(male), PP2, age and FBS. The combined risk factors can be identified using the MLP model. Those are total cholesterol and body weight, which is consistent with the result of other clinical studies. From this experiment we have learned that MLP can be applied to the combined risk factor analysis of biological data which can not be provided by the conventional statistical method.

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Knowledge, Compliance and Levels of Risk Factor Recognition for Needlestick Injuries in Student Nurses (간호대학생의 주사침 자상에 대한 지식, 이행 및 위험인식)

  • Park Sun-Nam;Lee Eun-Young;Kim Kyung-Mi;Han Suk-Jung
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.12 no.3
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    • pp.337-346
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    • 2005
  • Purpose: The purpose of this study was to investigate the levels in student nurse of knowledge, compliance and risk factor recognition for needlestick injuries. Method: Nine hundred and thirty eight(938) student nurse from 3 universities and 3 junior colleges participated in this study. Completed questionnaires were collected between October and November 2004. They were analyzed by using the descriptive statistics and $x^2$-test, t-test with the SAS program, Results: There were no significant differences in the general characteristics of participants between the two groups-Needlestick Injury(NSI) group and non-Needle stick Injury(non-NSI) group. The scores for knowledge levels of treatment after needle stick injuries and the risk factor recognition level were significantly higher in the NSI group. The scores for performance level as to handling and using needles after needlestick injuries were significantly higher in the non-NSI group. Conclusion: It is necessary to develop a preventive program to decrease the needlestick injury rate among student nurse.

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