• 한국통신학회논문지
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• 제24권6A호
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• pp.881-887
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• 1999

In this paper, were introduce two types of equalizers, called equalizer-a and equalizer-b, applying to wireless communications having unknown channel characteristics. The equalizer-a, which has the single sample detector with equalizer system, is developed while the equalizer-b has the partition detectors with the same system used in equalizer-a. The methodologiy we adopt for designing the equalizers is that the sample space is partitioned into finite number of regions by using quantiles, which are estimated by robbins-monro stochastic approximation (RMSA) algorithm, and the coefficients of equalizers are calculated based on nonlinear minimum mean, square error (MMSE) algorithm. Through the computer simulation, the equalizers show much better performance in equiprobably partitioned sample subspaces of observations than the single sample detector and the detector, which has the conventional equalizer, in unquantized observation space under various noise environments.

• 응용통계연구
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• 제11권2호
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• pp.233-246
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• 1998

1995년 가축통계 총조사자료에 기초하여 1998년부터의 향후 5년간의 표본설계를 하였다. 먼저 본 설계에서는 시도별 변이계수가 목표인 점을 고려하여 농가별 사육마리수를 전체사육마리수로 나눈 사육비율을 구한 다음 이를 전수기준과 총화에 이용하였다. 전수농가기준은 전수농가를 제외 한 후 조사구의 축종별 사육비율의 분산이 일정하게 하는 기준을 정하였고, 층화는 네축종중 최 대사육비율이 비슷한 조사구를 complete linkage 방법에 의해 층화하였다. 충의 개수는 층화에 따른 표본개수를 최소화하는 충의 수를 선정하였다. 또한 표본설계과정상의 해결하기 힘들었던 문제점을 열거하였다.

• Journal of the Korean Statistical Society
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• 제3권1호
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• pp.3-12
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• 1974

The two-stage sequential test, suggested by Baker [2] for testing hypotheses $H_0:\mu=\mu_0$ and $H_1:\mu=\mu_1$ of $N(\mu,\sigma^2)$ with the unknown $\sigma^2$ would not be amenable for applications unles some cluses on the choice of the first-stage sample size are available. The study in this paper is intended to shed some light on the size of the first-stage sample. An approximate method is used to estimate an optimal initial sample size that minimizes the average sample number. In brief, the optimal size is a strictly monotone decreasing function of the quantity $(\mu_1-\mu_0)/\sigma$. Empirical and simulation results are used to ascertain the negligible effect of possible errors due to approximations and assumptions used.

• Journal of Acupuncture Research
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• 제21권5호
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• pp.205-218
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• 2004

Objectives : The purpose of this experiment is to study on the anti-cancer, anti-metastasis and immune response improvement effects of Herbal-acupuncture with Carthami Flos infusion solution(CTT-HAS). Methods : We injected Carthami Flos infusion solution into Chung-wan(CV12) of C57BL/6 mouse which is corresponding to human Chung-wan(CV12). We observed its effect on the number of $CD25^{+}/CD4^{+}$, $CD8^{+}/CD3e^{+}$, $CD69^{+}/B220^{+}$, $NK^{+}/CD3e^{+}$ cells in mouse PBMCs, the number of the pulmonary colony, and the effect on MST and ILS of C57BL/6 mice implanted intravenously with B16-F10 melanoma. Results Conclusions : 1. The spleen cells proliferation of the sample groups treated with CTT-HAS extract has increased significantly compared with that of the control group. 2. The percentage of the $CD25^{+}/CD4^{+}$, $CD8^{+}/CD3e^{+}$, $CD69^{+}/B220^{+}$, $NK^{+}/CD3e^{+}$ cells in C57BL/6 mouse PBMCs of the sample groups treated with CTT herbal-acupuncture has increased compared with that of the control group. 3. The lung colony number of the sample groups CTT Herbal-acupuncture has decreased significantly compared with that of the control group. 4. MST and ILS of the sample groups CTT herbal-acupuncture have increased significantly compared with those of the control group.

• Korean Journal of Acupuncture
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• 제21권1호
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• pp.79-93
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• 2004

Objectives and methods : To study on the anti-cancer, anti-metastasis and immune response improvement effects of Herbal-acupuncture with Sinomenii acuti Lignum infusion solution(SAL-HAS), we injected Sinomenii acuti Lignum infusion solution into Joksamni$(ST_{36})$ of C57BL/6 mouse which is corresponding to human Joksamni(ST36). We observed its effect on the number of $CD25^+/CD4^+,\;CD8^+/CD3e^+,\;CD69^+/B220^+,\;NK1.1^+/CD3e^+$ cells in mouse PBMCs(peripheral blood mononuclear cells), the number of the pulmonary colony, and the effect on MST(mean survival time) and ILS(increase in MST over control) of C57BL/6 mice implanted intravenously with B16-F10 melanoma. Results and Conclusions : 1. The spleen cells proliferation of the sample groups treated with SAL-HAS extract has increased significantly compared with that of the control group. 2. The percentage of the $CD25^+/CD4^+,\;CD8^+/CD3e^+,\;CD69^+/B220^+,\;NK1.1^+/CD3e^+$ cells in C57BL/6 mouse PBMCs of the sample groups treated with SAL-HAS has increased compared with that of the control group. 3. The pulmonary colony number of the sample groups SAL-HAS has decreased significantly compared with that of the control group. 4. MST and ILS of the sample groups SAL-HAS have increased significantly compared with those of the control group.

• Korean Journal of Acupuncture
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• 제20권3호
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• pp.115-128
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• 2003

Objectives and methods :　Study the anti-cancer, anti-metastasis and immune response improvement effects of Herbal-acupuncture with Evodiae Fructus infusion solution, we injected Evodiae Fructus infusion solution into Zusanli(St36) of C57BL/6 mouse which is corresponding to human Zusanli(St36). We observed its effect on the number of $CD25^+/CD4^+,\;CD8^+/CD3e^+,\;CD69^+/B220^+,\;NK1.1^+/CD3e^+$ cells in mouse PBMCs, the number of the pulmonary colony , MST and ILS of C57BL/6 mice implanted intravenously with B16-F10 melanoma. Results and Conclusions : The spleen cells proliferation of the sample groups treated with EDR-HAS extract has increased significantly compared with that of the control group. The percentage of the $CD25^+/CD4^+,\;CD8^+/CD3e^+,\;CD69^+/B220^+,\;NK1.1^+/CD3e^+$ cells in C57BL/6 mouse PBMCs of the sample groups treated with EDR herbal-acupuncture has increased compared with that of the control group. The lung colony number of the sample groups treated with EDR herbal-acupuncture has decreased significantly compared with that of the control group. MST and ILS of the sample groups treated with EDR herbal-acupuncture have increased significantly compared with those of the control group.

• 한방안이비인후피부과학회지
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• 제18권1호
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• pp.13-26
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• 2005

Experimental drug was applied to a white male mouse taken ill with allergic contact dermatitis to investigate the effects of Yanghyulsamultanggamibang. 1. In case of skin moisture, when it was checked 72 hours later, there showed up meaningful differences among the normal, control, and sample groups. Especially, the moisture increased more noticeably in the sample group than in the control group. 2. With regards to RBC count in blood, it increased more in the control and sample groups than in the normal group when it was checked both in 24 hours and 72 hours. When it was checked in 48 hours, the number of RBC in the sample group increased the most, and the count in the control group increased more than in the normal group. 3. About the neutrophil rate in WBC count, it increased meaningfully more both on the control and sample groups than in the normal group in 24 hours. When the rate was checked in 48 hours, it increased the most in the sample group, and it increased more in the control group than in the normal group. When in checked72 hours later, it increased substantially more in the control group than both the sample and normal group. 4. As of the lymphocyte rate in WBC count, when measured in 24 hours, it increased in the normal group than in the control and sample groups. In 48 hours, it increased the most in the normal group, and it increased meaningfully more in the control group than in the sample group. 5. Regarding the total IgE, when measured 24 hours later, it increased noticeably more in the normal group than in the control and sample groups. In 48 hours, there showed up substantial differences among the normal, control and sample groups. In particular, it increased meaningfully more in the control group than in the sample group. 6. When the sample of skin tissue was examined, the corneal layer restoration increased more in the sample group than in the normal group. The above-mentioned results prove that Yanghyulsamultanggamibang can be taken when allergic contact dermatitis develops on the skin. Long-term observation afterward is also advised.

• 한국환경성돌연변이발암원학회지
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• 제15권2호
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• pp.115-121
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• 1995

Bacterial mutagenicity of shellfish or canned products of red-muscle fish affected by hot-airdry processings and/or during storages was investigated by Ames preincubation method. Mussel (Mytilus edulis) and surf clam (Tapes japonica) dried under either 40$\circ$C, 50$\circ$C or 60$\circ$C until remained about 25 % water content was stored at 4$\circ$C or 25$\circ$C for 6 months. Commercially available canned product of pacific saury (Cololabis saira) and mackerel saury (Scotnberjaponicus), whose producer or date of manufacture was identical each other, was stored at 25$\circ$C for 6 months. Mutagenic substances from sample (25 g dry weight) were extracted and purified for mutagenicity assay against S. typhitnurium TA98 by the simultaneous distillation extraction (SDE) method (Lee et al. 1955). Mutagenicity of sample was expressed number of revertant per 25 g dry sample. Number of revertant from unheated mussel sample was appeared to be 135, relative to 22 from unheated surf clam sample. Mutagenicity of both shellfish was strongly affected by heat treatment, but a lesser extent by storage conditions, even at 25$\circ$C for 6 months. Revertants of the mussel sample dried at 40$\circ$C, 50$\circ$C, or 60$\circ$C was found to be 227, 779, and 883, respectively. Similar, but lower, mutagenicity was observed from the sample of surf clam dried at 40$\circ$C, 50$\circ$C, or 60$\circ$C than mussel. Mutagenicity of canned pacific saury and mackerel samples was not influenced by storage conditions. Number of revertant from pacific saury was 175 which was relatively higher than 5 from mackerel. Mutagenicity of fresh pacific saury and mackerel samples was significantly higher than that of their counterparts from canned products. These results indicate that mutagenicity of the shellfish was affected by heat treatment (40$\circ$C, 50$\circ$C, or 60$\circ$C) used for drying process, but not much by storage for 6 months at 4$\circ$C or 25$\circ$C and the mutagenicity of canned products of red-muscle fish was not influenced by storage, even at 25$\circ$C for 6 months.

• 대한한방내과학회지
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• 제21권1호
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• pp.74-86
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• 2000

Objectives : This is the experimental paper to study the curative and preventive effects of Dansambohyultang, Methods : Oriental herb medicine for gastro-intestinal disease caused by stress, on the rats put under the stress through starvation, heating and immoblization, the author used four different group; the normal group, which was not put under stress and well fed, and the control group, to which the drug was not administered and put under the stress through starvation, heating and immoblization, the Sample I, to which the drug was administered before they were put under stress, the Sample lI, to which the drug was administered after they were put under stress. Results : When a Masson's trichrome stain method was applied to the control group, a small size of ulcer was found in the fundus and the pylorus, and atrophy was observed in the neck region of mucous membrane. When the drug was administered to the Sample I and the Sample II, the former recovered from the ulcer and atrophy to almost normal and showed better results than the latter. When a Masson's trichrome stain method was applied to the control group, atrophy of mucous membrane was found all over the intestines. When the drug was administered to the Sample I and the Sample ll, the curative and recovered effects was seen in both, but the former showed better results than the latter. After application of Mayer's hematoxylin stain method, the observation of numerical changes of goblet cells in the small intestines showed the most significant decrease in the control group. In the Sample I, the number of the cells in the duodenum, the jejunum and the ileum returned to an almost normal level. In the Sample II, a slight increase was observed only in the ileum. After application of Mayer's hematoxylin stain method, the observation of numerical changes of goblet cell in the large intestines showed a significant decreased in the control group. Both the Sample I and the Sample II showed an increase in the number of goblet cells in comparison with the control group. When a serotonin-immunoreaction test was applied, the control group showed a general decrease in the number of gastro-entero-endocrine cells, The Sample I showed the effect in all over gastro.intestinal tract as compared with control group and the Sample II showed the effect in all over gastro-intestinal tract except the duodenum and the former showed better results than the latter. Conclusion : According to the above results, the regions which are most sensitive to stress were observed to the ileum and the colon. It was concluded that Dansambohyultang has a remedical value particularly on the abnormalities caused by stress in all over gastro-intestinal tract and it was found to be more effective in the Sample I than in the Sample ll. Judging from the fact that the Sample I showed better results than the Sample ll, Dansambohyultang can be said to have a preventive effect more than a curative effect on gastro-intestinal tract disease.

• 한국식품과학회지
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• 제33권1호
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• pp.100-106
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• 2001

본 연구에서는 김치를 동결건조하여 $0^{\circ}C,\;5^{\circ}C,\;28^{\circ}C$에 60일간 저장하면서 동결건조/저장/복원시료와 동결건조/저장/미(未)복원시료의 젖산균수, 관능적 특성, 형태 및 색상의 변화를 관찰하여 다음과 같은 결과를 얻었다. (1) 동결건조/저장/복원시료의 저장 중 젖산균수의 변화를 보면, $0^{\circ}C$와 $5^{\circ}C$의 경우는 젖산균수가 점차 감소하여 10일과 30일 시료가 바로 앞의 시료와 비교하여 유의적인 차이를 보였으며(p<0.05), $28^{\circ}C$의 경우는 10일, 20일, 30일 시료가 각각 바로 앞의 시료와 유의적인 차이를 보였다(p<0.05). (2) 동결건조에 의한 김치의 관능적 특성의 변화를 보면, 표준시료(동결건조하지 않은 시료)와 비교하여 동결건조/복원시료의 전반적인 기호성, 맛, Moistness, Chewiness가 다소 저하하였다. 그러나 동결건조/복원시료의 기호성은 비교적 양호하였다. (3) 동결건조/저장/복원시료의 전반적인 기호성은 10일 시료의 경우 표준시료(동결건조하지 않은 시료)보다 다소 낮았으며, 표준시료와 $0^{\circ}C$, $5^{\circ}C$ 시료 사이에, 그리고 $0^{\circ}C$, $5^{\circ}C$ 시료와 $28^{\circ}C$ 시료 사이에 유의적인 차이가 있었다(p<0.05). 50일 시료의 경우는 $28^{\circ}C$ 시료의 전반적인 기호성이 $28^{\circ}C$/10일 시료보다 현저하게 저하하였다. (4) 동결건조/저장/미복원 시료의 저장 중 관능적 특성의 변화를 보면, 표준시료($0^{\circ}C$ 저장 시료)와 비교하여 $5^{\circ}C$ 시료는 차이가 없었으나, $28^{\circ}C$ 시료는 저장 10일에 전반적인 기호성, 맛, 조직감, Crispness가 저하하기 시작하였고, 50일후에는 냄새, 60일후에는 색상도 표준시료와 차이가 있었다.