• Title/Summary/Keyword: scattered fluorescence intensity

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Penetration depth and Wave Propagation in Random Media (무질서한 매질에서 침투깊이와 파동 전파)

  • Kim, Ki-Jun;Sung, Ki-Chun
    • Journal of the Korean Applied Science and Technology
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    • v.23 no.1
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    • pp.70-76
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    • 2006
  • The influence of fluorophor, scatterer, absorber in turbid materials by light scattering were interpreted for the scattered fluorescence intensity and wavelength, it is studied the molecular property by laser induced fluorescence spectroscopy. It can be found that the effects of optical property are penentrated in scattering media by the optical $parameters({\mu}s$, ${\mu}a$, ${\mu}t$, ${\gamma}$, ${\rho})$. The value of scattering coefficient ${\mu}s$ is large appeared by means of the increasing particles of scattering, it can be found that the slope appears exponentially as a function of distance from laser source to detector. It may also utilize in designing the best model for oil chemistry, laser medicine and application of medical engineering.

A Study on Spectra of Laser Induced Fluorescence in Phantom (Phantom에서 Laser Induced Fluorescence의 스펙트라에 관한 연구)

  • Kim, Ki-Jun;Sung, Ki-Chun
    • Journal of the Korean Applied Science and Technology
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    • v.16 no.4
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    • pp.329-335
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    • 1999
  • The influences of fluorophor, scatterer, and absorber in turbid material by light scattering were interpreted for the scattered fluorescence intensity and wavelength. The molecular properties have been studied by laser induced fluorescence spectroscopy in phantom. It has been found that the effects of optical properties in scattering media could be investigated by the optical parameters(${\mu}_a$, ${\mu}_a$, ${\mu}_t$). Experimental and Monte Carlo Simulation method for modelling light transport in tissue was applied. The experimental results using a phantom were discussed and compared with those obtained through Monte Carlo Simulation. It may also aid in designing the best model for oil chemistry, medicine and application of medical engineering.

Analysis of Hematoporphyrin Derivative by Design and Manufacture of High Resolution Charge Coupled Device in Spectrometry (분광기에 고 분해능 Charge Coupled Device의 설계 및 제작에 의한 Hematoporphyrin Derivative의 분석)

  • Kim, Ki-Jun
    • Journal of the Korean Applied Science and Technology
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    • v.22 no.1
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    • pp.77-83
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    • 2005
  • The influence of fluorescence, scattering, and absorbance in turbid material by light scattering was interpreted by the scattered fluorescence intensity and wavelength. The effect of optical property in scattering media was investigated. It is very important to study the charge coupled device(CCD) in spectrometry because we can use the molecular energy level, molecular structure, absorption or emission, intermolecular reaction, weakly bound molecular energy, photochemistry, fluorescence and photodynamic therapy. CCD is very essential to study the molecular structure and medical engineering combined laser spectroscopy in the modem physical and chemistry. Accordingly, this study has designed and manufactured the electromagnetic spectrometry with CCD, and has analyzed the hematoporphyrin derivative.

A Study on the Measurements of Beam Wave Propagation and Fluorescence Spectroscopy in Particles Media (입자매질에서 빔파동전파와 형광분광 측정에 관한 연구)

  • Kim, Ki-Jun;Lee, Jou-Youb;Sung, Wan-Mo
    • Journal of the Korean Applied Science and Technology
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    • v.31 no.2
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    • pp.167-175
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    • 2014
  • The influences of fluorescence, scattering, and flocculation in turbid material were interpreted for the scattered fluorescence intensity and wavelength, it has been studied the molecular properties by the spectroscopy of laser induced fluorescence(LIF). The effects of optical properties in scattering media have been found by the optical parameters(${\mu}_s$, ${\mu}_a$, ${\mu}_t$). Flocculation is an important step in many solid-liquid separation processes and is widely used in Photodynamic therapy. The interactions of several colloid particles can come into play which have major effect on the flocculation and LIF process. We measured scattering and fluorescence spectra of the sample for in vitro as function of concentration from lase source to detector. The value of scattering coefficient ${\mu}_s$ is large by means of the increasing particles of scatterer. Therefore, Phorphyrin A is larger than Phorphyrin C in scattering intensity ${\mu}_s$, but Phorphyrin A is smaller than Phorphyrin C in penetration depth ${\delta}$.

A Study on Laser Induced Fluorescence and Coagulation in Particle Transport Mode (입자 이동 방식에서 Laser Induced Fluorescence와 뭉침에 관한 연구)

  • Kim, Ki-Jun
    • Journal of the Korean Applied Science and Technology
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    • v.23 no.4
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    • pp.340-346
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    • 2006
  • The influences of fluorescence, scattering, and flocculation in turbid material by light scattering were interpreted for the scattered fluorescence intensity and wavelength, it has been studied the molecular properties by the spectroscopy of laser induced fluorescence (LIF). The effects of optical properties in scattering media have been found by the optical $parameters({\mu}_s,\;{\mu}_a,\;{\mu}_t)$. Flocculation is an important step in many solid-liquid separation processes and is widely used. When two particles approach each other, interactions of several colloid particles can come into play which may have major effect on the flocculation and LIF process, The value of scattering coefficient ${\mu}_s$ is large by means of the increasing particles of scatterer it has been found that the slope decays exponentially as a function of distance from laser source to detector. It may also aid in designing the best model for oil chemistry, biopharmaceutical products, laser medicine and application of medical engineering on LIF and coagulation in particle transport mode.

The Properties of Beam Intensity Scanner(BInS) in IMRT with Phantom for Three Dimensional Dose Verification

  • Young W. Vahc;Park, Kwangyl;Byung Y. Yi;Park, Kyung R.;Lee, Jong Y.;Ohyun Kwon;Park, Kwangyl;Kim, Keun M.
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.64-64
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    • 2003
  • Objectives: Patient dose verification is clinically the most important parts in the treatment delivery of radiation therapy. The three dimensional(3D) reconstruction of dose distribution delivered to target volume helps to verify patient dose and determine the physical characteristics of beams used in intensity modulated radiation therapy(IMRT). We present Beam Intensity Scanner(BInS) system for the pre treatment dosimetric verification of two dimensional photon intensity. The BInS is a radiation detector with a custom made software for relative dose conversion of fluorescence signals from scintillator. Methods: This scintillator is fabricated by phosphor Gadolinium Oxysulphide and is used to produce fluorescence from the irradiation of 6MV photons on a Varian Clinac 21EX. The digitized fluoroscopic signals obtained by digital video camera will be processed by our custom made software to reproduce 3D relative dose distribution. For the intensity modulated beam(IMB), the BInS calculates absorbed dose in absolute beam fluence, which are used for the patient dose distribution. Results: Using BInS, we performed various measurements related to IMRT and found the followings: (1) The 3D dose profiles of the IMBs measured by the BInS demonstrate good agreement with radiographic film, pin type ionization chamber and Monte Carlo simulation. (2) The delivered beam intensity is altered by the mechanical and dosimetric properties of the collimating of dynamic and/or static MLC system. This is mostly due to leaf transmission, leaf penumbra, scattered photons from the round edges of leaves, and geometry of leaf. (3) The delivered dose depends on the operational detail of how to make multileaf opening. Conclusions: These phenomena result in a fluence distribution that can be substantially different from the initial and calculative intensity modulation and therefore, should be taken into account by the treatment planing for accurate dose calculations delivered to the target volume in IMRT.

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Studies on the Measurements of Optical Parameters in Turbid Material by Light Scattering (혼탁 매질에서 광산란에 의한 광학적 파라미터들의 측정에 관한 연구)

  • Kim, Ki-Jun;Sung, Ki-Chun
    • Journal of the Korean Applied Science and Technology
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    • v.12 no.2
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    • pp.151-156
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    • 1995
  • The influences of fluorophor, scatterer, absorber in turbid material by light scattering were interpreted for the scattered fluorescence intensity and wavelength, it has been studied the molecular properties by laser induced fluorescence spectroscopy. It has been found that the effects of optical properties in scattering media by the optical parameters(${\mu}_{s}$, ${\mu}_{a}$, ${\mu}_{t}$). The value of scattering coefficient ${\mu}_{s}$ is large by means of the increasing particles of scatterer, it has been found that the slope decays exponentially as a function of distance from laser source to detector. It may also aid in designing the best model for oil chemistry, laser medicine and application of medical engineering.

Measurement on the Methotrexate in L-${\alpha}$-Phosphatidylcholine Media by Light Sacttering (L-${\alpha}$-Phosphatidylcholine 매질에서 빔산란에 의한 Methotrexate의 측정)

  • Kim, Ki-Jun;Lee, Joo-Youb
    • Journal of the Korean Applied Science and Technology
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    • v.30 no.2
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    • pp.251-257
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    • 2013
  • The influences of Methotrexate as fluorophor, scatterer, absorber in turbid material by light scattering were interpreted for the scattered fluorescence intensity and wavelength, it has been studied the molecular properties by laser induced fluorescence spectroscopy. It has been found that the effects of optical properties in scattering media by the optical parameters((${\mu}_s$, ${\mu}_a$, ${\mu}_t$). The value of scattering coefficient ${\mu}_s$ is large by means of the increasing particles of L-${\alpha}$-Phosphatidylcholine, it has been found that the slope decays exponentially as a function of depth from laser source to detector. It may also aid in designing the best model for oil chemistry, laser medicine and application of medical engineering.

Verification on Diffusion of Beam Propagation in Randomly Distributed Scattering Medium (무질서하게 분포된 산란매질에서 빔전파의 확산에 관한 검증)

  • Kim, Ki-Jun;Lee, Hoo-Seol
    • Journal of the Korean Applied Science and Technology
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    • v.24 no.4
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    • pp.354-361
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    • 2007
  • The distribution of light in a randomly scattering medium can represent problems found in many area. Particularly, in the clinical application of lasers for Photodynamic therapy(PDT) or in the fluorescence spectroscopy for biological tissue, turbidity plays a very important role. The influences of fluorophor, scatterer, and absorber in turbid material by light scattering were interpreted for the scattered fluorescence intensity and wavelength. The molecular properties have been studied by laser induced fluorescence spectroscopy in scattering medium as tissue. It has been found that the effects of optical properties in scattering media could be investigated by the optical $parameters({\mu}_s$, ${\mu}_a$ ,${\mu}t)$. Experimental and Monte Carlo simulation method for modelling light transport in tissue was applied. The experimental results using a randomly distributed scattering medium were discussed and compared with those obtained through Monte Carlo simulation. It'll be also important in designing the best model for oil chemistry, medicine and application of medical engineering.

A Study on Wave Propagation and Scattering in Purple Membrane and β-carotene (Purple Membrane과 β-carotene에서 산란과 파동전파에 관한 연구)

  • Kim, Ki-Jun;Park, Tae-Sul;Sung, Wan-Mo
    • Journal of the Korean Applied Science and Technology
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    • v.33 no.1
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    • pp.136-142
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    • 2016
  • The influences of fluorescence, scattering, and flocculation in random media were interpreted for the scattered fluorescence intensity and wavelength, it has been studied the molecular properties by the spectroscopy of laser induced fluorescence(LIF). The effects of optical properties in scattering media have been found by the optical parameters(${\mu}_s$, ${\mu}_a$, ${\mu}_t$). Flocculation is an important step in many solid-liquid separation processes and is widely used in Photodynamic therapy. The interactions of several colloid particles can come into play which have major effect on the flocculation and LIF process. We measured scattering and fluorescence spectra of the sample in vitro as function of distance from lase source to detector. The value of scattering coefficient ${\mu}_s$ is and ${\beta}$-carotene were measured as larger values(I, ${\delta}$) by means of closer distance from source to detector.