• Journal of Institute of Control, Robotics and Systems
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• v.14 no.3
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• pp.318-325
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• 2008

In this paper, a dynamic backoff adjustment method of IEEE 802.15.4 is proposed for time-critical sporadic data in a noisy factory environment. For this, a superframe of IEEE 802.15.4 is applied to a real-time mixed data (periodic data, sporadic data, and non real-time message) transmission in factory communication systems. To guarantee a channel access of real-time sporadic(non-periodic) data, a transmission method using the dynamic backoff is applied to wireless control networks. For the real-time property, different initial BE, CW parameters are used for the dynamic backoff adjustment method. The simulat-ion results show an enhancement of the real-time performance of sporadic emergency data. The proposed method provides the channel access of real-time sporadic data efficiently, and guarantee real-time transmission simultaneously within a limite-d timeframe.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.747-752
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• 2004

Researches about scheduling of the distributed real-time systems have been proposed. However, they have some weak points, not scheduling both sporadic and periodic tasks and messages or being unable to guaranteeing the end-to-end constraints due to omitting precedence relations between sporadic tasks. So this paper proposes a new scheduling method for distributed real-time systems consisting of sporadic and periodic tasks with precedence relations and sporadic and periodic messages, guaranteeing end-to-end constraints. The proposed method is based on a binary search-based period assignment algorithm, an end-to-end laxity-based priority assignment algorithm, and three kinds of schedulability analysis, node, network, and end-to-end schedulability analysis. In addition, this paper describes the application model of sporadic tasks with precedence constraints in a distributed real-time system, shows that existing scheduling methods such as Rate Monotonic (RM) scheduling are not proper to be applied to the system having sporadic tasks with precedence constraints, and proposes an end-to-end laxity-based priority assignment algorithm.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.16
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• pp.7195-7200
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• 2015

Background: Since seventeen employees of an offset printing company in Osaka, Japan developed cholangiocarcinoma it has become recognized as an occupational cancer. This study investigated the differences of clinical features between occupational cholangiocarcinoma and sporadic young-onset cholangiocarcinoma. Materials and Methods: Thirty-four young adults (<50 years old) with sporadic cholangiocarcinoma were extracted from the Rosai Hospital Group database (sporadic group) and their clinical features were compared with those of 17 patients with occupational cholangiocarcinoma (occupational group). Results: The 34 patients in the sporadic group were treated for cholangiocarcinoma at 16 different Rosai hospitals. There were significant differences of age (p<0.01), gender (p<0.01), abnormal laboratory tests (p<0.01), and tumor location (p<0.01) between the two groups. The percentage of patients with abnormal laboratory tests was significantly higher in the occupational group than in the sporadic group (p<0.001). Regional dilation of bile ducts, which is a characteristic of occupational cholangiocarcinoma, was not observed in the sporadic group. Conclusions: No cluster of cholangiocarcinoma cases was identified in the Rosai Hospital database. There were differences of clinical features between occupational and sporadic cholangiocarcinoma, which might be helpful for diagnosing occupational cholangiocarcinoma in the future.

• Journal of Institute of Control, Robotics and Systems
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• v.11 no.2
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• pp.175-185
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• 2005

The scheduling methods of the distributed real-time systems have been proposed. However, they have some weak points. They did not schedule both sporadic and periodic tasks and messages at the same time or did not consider the end-to-end constraints such as precedence relations between sporadic tasks. This means that system scheduling must guarantee the constraints of practical systems and be applicable to them. This paper proposes a new scheduling method that can be applied to more practical model of distributed real-time systems. System model consists of sporadic and periodic tasks with precedence relations and sporadic and periodic messages and has end-to-end constraints. The proposed method is based on a binary search-based period assignment algorithm, an end-to-end laxity-based priority assignment algorithm, and three kinds of schedulability analysis, node, network, and end-to-end schedulability analysis. In addition, this paper describes the application model of sporadic tasks with precedence constraints in a distributed real-time system, shows that existing scheduling methods such as Rate Monotonic scheduling are not proper to be applied to the system having sporadic tasks with precedence constraints, and proposes an end-to-end laxity-based priority assignment algorithm.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1995-1998
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• 2013

Objective: To study the expression of the mismatch repair proteins hMSH2 and nm23 in sporadic colorectal cancer, determine any inter-relationship, and further investigate any clinical significance. Methods: Expression of hMSH2 and nm23 proteins was assessed in 87 colorectal cancer tissues by SP immunohistochemistry, with analysis of survival using follow-up data. Results: In the sporadic colorectal cancer tissues, nm23 protein expression appeared independent of the histological type (P>0.05), but correlated with the invasion depth and lymphatic metastasis (P<0.05). In contrast, hMSH2 protein expression was not significantly correlated with these clinicopathologic features (P>0.05), although it positively correlated with that of nm23 protein in the sporadic colorectal cancers (rs=0.635, P<0.05). Combined expression of the two was found to be related with invasion depth, lymphatic metastasis and prognosis of sporadic colorectal cancer (P<0.05). Conclusion: nm23 protein level was related with the degree of malignancy, and could be used as an index to predict the invasion and metastasis potential. The expression of hMSH2 protein is positively correlated that of nm23 protein, and the combined expression of the two has certain guiding significance for the prognosis of sporadic colorectal cancer.

• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.97-100
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• 1997

Fieldbuses are used as the lowest level communication network for real-time communication in factory automation and process control systems. Data generated from field devices can be divided into three categories: sporadic real-time, periodic real-time and non real-time data. Since these data share one fieldbus network medium, it needs a method that allocate the limited bandwidth of fieldbus network to the sporadic real-time, periodic real-time and non real-time traffic. This paper introduces an implementation method of bandwidth allocation scheme introduced in [51 on PROFIBUS. Using the modified PROFIBUS FDL(Fieldbus Data Link layer), the bandwidth allocation scheme introduced in [51 is verified by the experiments.

• Journal of information and communication convergence engineering
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• v.10 no.4
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• pp.396-404
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• 2012

This paper proposes an analysis method to check the schedulability of a set of sporadic tasks under earliest deadline first (EDF) scheduler. The sporadic task model consists of subtasks with precedence constraints, arbitrary arrival times and deadlines. In order to determine the schedulability, we present an approach to find exact worst case response time (WCRT) of subtatsks. With the technique presented in this paper, we exploit the precedence relations between subtasks in an accurate way while taking advantage of the deadline of different subtasks. Another nice feature of our approach is that it avoids calculation time overhead by exploiting the concept of deadline busy period. Experimental results show that this consideration leads to a significant improvement compared with existing work.

• Proceedings of the KIEE Conference
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• 2004.05a
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• pp.59-61
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• 2004

Researches about scheduling distributed real-time systems have some weak points, not scheduling both sporadic and periodic tasks and messages or being unable to guaranteeing the end-to-end constraints due to omitting precedence relations between sporadic tasks. This paper describes the application model of sporadic tasks with precedence constraints in a distributed real-time system. It is shown that existing scheduling methods such as Rate Monotonic scheduling are not proper to be applied to the system having sporadic tasks with precedence constraints. So this paper proposes an end-to-end laxity-based priority assignment algorithm which considers the practical laxity of a task and allocates a proper priority to a task.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.619-624
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• 2013

Background: Colorectal cancer (CRC) exists in a more common sporadic form and less common hereditary forms, associated with the Lynch syndrome, familial adenomatous polyposis (FAP) and other rare syndromes. Sporadic CRC is believed to arise as a result of close interaction between environmental factors, including dietary and lifestyle habits, and genetic predisposition factors. In contrast, hereditary forms such as those related to the Lynch syndrome result from inheritance of germline mutations of mismatch repair (MMR) genes. However, in certain cases, the influence of low penetrance alleles in familial colorectal cancer susceptibility is also undeniable. Aim: To investigate the genotype frequencies of MLH1 promoter polymorphism -93G>A and to determine whether it could play any role in modulating familial and sporadic CRC susceptibility risk. Methods: A case-control study comprising of 104 histopathologically confirmed CRC patients as cases (52 sporadic CRC and 52 Lynch syndrome patients) and 104 normal healthy individuals as controls was undertaken. DNA was extracted from peripheral blood and the polymorphism was genotyped employing PCR-RFLP methods. The genotypes were categorized into homozygous wild type, heterozygous and homozygous variants. The risk association between these polymorphisms and CRC susceptibility risk was calculated using binary logistic regression analysis and deriving odds ratios (ORs). Results: When risk association was investigated for all CRC patients as a single group, the heterozygous (G/A) genotype showed a significantly higher risk for CRC susceptibility with an OR of 2.273, (95%CI: 1.133-4.558 and p-value=0.021). When analyzed specifically for the 2 types of CRC, the heterozygous (G/A) genotype showed significantly higher risk for sporadic CRC susceptibility with and OR of 3.714, (95%CI: 1.416-9.740 and p-value=0.008). Despite high OR value was observed for Lynch syndrome (OR: 1.600, 95%CI: 0.715-3.581), the risk was not statistically significant (P=0.253). Conclusion: Our results suggest an influence of MLH1 promoter polymorphism -93G>A in modulating susceptibility risk in Malaysian CRC patients, especially those with sporadic disease.

• Journal of Korean Neurosurgical Society
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• v.53 no.1
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• pp.1-5
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• 2013

Objective : The purpose of this study was to evaluate the characteristics and surgical outcomes of familial hemifacial spasm (HFS) and to discuss the role of genetic susceptibility. Methods : Between 2001 and 2011, 20 familial HFS patients with ten different pedigrees visited our hospital. The data from comprehensive evaluation of these patients, including clinical, radiological and electrophysiological data and surgical outcomes were reviewed to characterize familial HFS and to compare the characteristics between familial HFS and sporadic HFS. Results : According to the family tree, the inheritance pattern was difficult to define clearly using these data. Radiologic findings suggested that the vertebral artery (VA) was a more frequent offender in familial HFS than in sporadic cases (35.0% vs. 10.0%, p<0.001). Chi-square test showed that there were no correlation between VA tortuosity and underlying morbidity such as diabetes or hypertension (p=0.391). Eighteen out of 19 patients who underwent microvascular decompression showed no residual spasm. Other features of familial HFS overlap with sporadic cases. These findings suggest that certain genetic susceptibilities rather than hypertension or diabetes may influence vascular tortuosity and HFS development. Conclusion : In this study, familial HFS seems not so different from sporadic cases. Authors thought familial HFS could have heterogeneous etiology. Further study of familial HFS including clinical, anatomic, genetic, and molecular information may help identify a gene or trait that can provide insight into the mechanisms of sporadic and familial HFS.