• Title/Summary/Keyword: variable selection

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Comparison of vital sign stability and cost effectiveness between midazolam and dexmedetomidine during third molar extraction under intravenous sedation

  • Jun-Yeop, Kim;Su-Yun, Park;Yoon-Sic, Han;Ho, Lee
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.48 no.6
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    • pp.348-355
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    • 2022
  • Objectives: To compare the vital sign stability and cost of two commonly used sedatives, midazolam (MDZ) and dexmedetomidine (DEX). Patients and Methods: This retrospective study targeted patients who underwent mandibular third molar extractions under intravenous sedation using MDZ or DEX. The predictor variable was the type of sedative used. The primary outcome variables were vital signs (heart rate and blood pressure), vital sign outliers, and cost of the sedatives. A vital sign outlier was defined as a 30% or more change in vital signs during sedation; the fewer changes, the higher the vital sign stability. The secondary outcome variables included the observer's assessment of alertness/sedation scale, level of amnesia, patient satisfaction, and bispectral index score. Covariates were sex, age, body mass index, sleeping time, dental anxiety score, and Pederson scale. Descriptive statistics were computed including propensity score matching (PSM). The P-value was set at 0.05. Results: The study enrolled 185 patients, 103 in the MDZ group and 82 in the DEX group. Based on the data after PSM, the two samples had similar baseline covariates. The sedative effect of both agents was satisfactory. Heart rate outliers were more common with MDZ than with DEX (49.3% vs 22.7%, P=0.001). Heart rate was higher with MDZ (P=0.000). The cost was higher for DEX than for MDZ (29.27±0.00 USD vs 0.37±0.04 USD, P=0.000). Conclusion: DEX showed more vital sign stability, while MDZ was more economical. These results could be used as a reference to guide clinicians during sedative selection.

Effects of tongue strength training program combined with oral exercises on swallowing disorder, swallowing ability, and tongue pressure in the elderly (입체조를 병행한 혀 근력운동이 노인의 연하장애와 연하력 및 설압에 미치는 효과)

  • Nam-Suk Kim;Jung-Hwa Lee
    • Journal of Korean society of Dental Hygiene
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    • v.23 no.2
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    • pp.105-113
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    • 2023
  • Objectives: The purpose of this study is to verify the usefulness and practicality of the program in the daily life of the elderly by performing a three-dimensional tongue muscle exercise for the elderly to identify the dysphagia, swallowing ability, and tongue pressure. Methods: The subjects of the study were 29 elderly people aged 65 or older living in Busan, divided into a oral exercises group and tongue strength training program combined with oral exercises group, and operated 16 times for 8 weeks twice a week, and the pre and post-program evaluation was conducted in the 1st and 8th weeks. For variable selection, 7 general characteristics, 5 oral health-related characteristics, 5 Likert scale for swallowing disorder, repetitive swallowing ability test for swallowing power measurement, and tongue pressure measurement was used. Data analysis was conducted using SPSS window program 25.0 version (IBM), general characteristics and homogeneity tests, oral health-related characteristics and homogeneity tests were chi-square test, swallowing disorder, swallowing ability, and change in tongue pressure were paired t-test, Wilcoxon signed rank test, t-test, Mann-Whitney U test for swallowing disorder and changes in swallowing ability and tongue pressure, and Spearman's correlation for the relationship between swallowing disorder and swallowing ability and tongue pressure. Results: As a result of tongue strength training program combined with oral exercise, both relieve swallowing disorder and improve low eating and tongue pressure than oral exercise, and the difference in improvement effects of both relieve swallowing disorder, swallowing ability, and tongue pressure is higher. Conclusions: Based on the results of this study, it is believed that simple and practical oral muscle function reinforcement products and practical use are needed, and institutional devices to seek oral health promotion programs for the elderly are needed.

Investigation of AI-based dual-model strategy for monitoring cyanobacterial blooms from Sentinel-3 in Korean inland waters

  • Hoang Hai Nguyen;Dalgeun Lee;Sunghwa Choi;Daeyun Shin
    • Proceedings of the Korea Water Resources Association Conference
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    • 2023.05a
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    • pp.168-168
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    • 2023
  • The frequent occurrence of cyanobacterial harmful algal blooms (CHABs) in inland waters under climate change seriously damages the ecosystem and human health and is becoming a big problem in South Korea. Satellite remote sensing is suggested for effective monitoring CHABs at a larger scale of water bodies since the traditional method based on sparse in-situ networks is limited in space. However, utilizing a standalone variable of satellite reflectances in common CHABs dual-models, which relies on both chlorophyll-a (Chl-a) and phycocyanin or cyanobacteria cells (Cyano-cell), is not fully beneficial because their seasonal variation is highly impacted by surrounding meteorological and bio-environmental factors. Along with the development of Artificial Intelligence (AI), monitoring CHABs from space with analyzing the effects of environmental factors is accessible. This study aimed to investigate the potential application of AI in the dual-model strategy (Chl-a and Cyano-cell are output parameters) for monitoring seasonal dynamics of CHABs from satellites over Korean inland waters. The Sentinel-3 satellite was selected in this study due to the variety of spectral bands and its unique band (620 nm), which is sensitive to cyanobacteria. Via the AI-based feature selection, we analyzed the relationships between two output parameters and major parameters (satellite water-leaving reflectances at different spectral bands), together with auxiliary (meteorological and bio-environmental) parameters, to select the most important ones. Several AI models were then employed for modelling Chl-a and Cyano-cell concentration from those selected important parameters. Performance evaluation of the AI models and their comparison to traditional semi-analytical models were conducted to demonstrate whether AI models (using water-leaving reflectances and environmental variables) outperform traditional models (using water-leaving reflectances only) and which AI models are superior for monitoring CHABs from Sentinel-3 satellite over a Korean inland water body.

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Network pharmacoligical analysis for selection between Saposhnikoviae Radix and Glehniae Radix focusing on ischemic stroke (방풍(防風)과 해방풍(海防風) 중 뇌경색 연구에 더욱 적합한 약재 선정을 위한 네트워크 약리학적 분석)

  • Jin Yejin;Lim Sehyun;Cho Suin
    • Herbal Formula Science
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    • v.31 no.3
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    • pp.171-182
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    • 2023
  • Objectives : Saposhnikoviae Radix (SR) and Glehniae Radix (GR) have been frequently used in traditional medicine to treat diseases related to 'wind' syndrome, but there have been cases where it has been mixed in a state where the plant of origin is not clear. In this study, to select materials for conducting preclinical cerebral infarction research, the network pharmacology analysis method was used to select suitable medicinal materials for the study. Methods : In this study, a Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) based network pharmacology analysis method was used, and oral bioavailability (OB), drug likeness (DL), Caco-2 and BBB permeability were utilized to select compounds with potential activity. For the values of each variable used in this study, OB ≥ 20%, DL ≥ 0.18, Caco-2 ≥ 0, and BBB ≥ -0.3 were applied, then networks of bioactive compounds, target proteins, and target diseases was constructed. STRING database was used to construct a protein-protein interaction network. Results : It was confirmed that SR rather than GR has various target proteins and target diseases based on network pharmacological analysis using TCMSP database. And it was analyzed that the bioactive compounds only in SR act more on neurovascular diseases, and both drugs are expected to be effectively used for cardiovascular diseases. Conclusions : In our future study, SR will be used in an ischemic stroke mouse model, and the mechanism of action will be explored focusing on apoptosis and cell proliferation.

Active Ageing and Inter-Generational Relationship: Empirical Evidence from Public Job Creation Program for Elderly (적극적 노년생활과 세대 간 가족관계 - 노일일자리사업 데이터를 활용한 실증분석 -)

  • Lee, Suk-Won
    • 한국정책학회보
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    • v.21 no.1
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    • pp.337-361
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    • 2012
  • This study is conducted to provide empirical evidences which support that the problems of social isolation and loneliness of elderly can be alleviated by intervening the inter-generational relationship of the elderly by means of active ageing policy. The major empirical challenge to address this question is the possibility of selection bias caused by reversed causal relationship. To address this challenge, I constructed comparison group with 'Eligible Non-Participants' (ENP), and used instrumental variable method to estimate the empirical model. My findings indicate that inter-generational relationship, both in the aspects of economical solidarity and associational solidarity, is significantly improved as time use pattern of the elderly becomes more active. The improvement effect is intensively observed for the group of elderly who do not live with their adult children. The important policy implication of these findings is that the improvement of inter-generational relationship can be added as a new benefit of active ageing policy.

Effect of inwards FDI on new venture creation, industrialization and economic growth in Russia: A timeseries ARDL approach

  • Kristina, Yuryeva;He, Zhengquan
    • Asia Pacific Journal of Business Review
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    • v.7 no.1
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    • pp.1-21
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    • 2022
  • This research aimed to clarify the impacts casted by inwards FDI on New venture creation, industrialization, and the economic growth of Russia. For all of these variables, data was taken about Russia from the site of The World Bank, and the selected duration was from 1995 to 2019. The total duration of the data taken was from 24 years. The time duration was well enough for applying the A.R.D.L. approach to the time series data of the study. This research used the unit root test to know the presence of the unit root for each variable, the lag order selection was made for the data, the bounds cointegration test was also applied, and ARDL Model was used to know about the different effects. With the help of the results derived, it was observed that the impact of private sector investment on new venture creation is significant. In contrast, foreign direct investment and research and development (R&D) effects on new venture creation are insignificant. It was also observed from the results that the impact of R&D on industrialization in Russia is significant, while the effects of FDI and the impact of private sector investment on industrialization in Russia is insignificant. We have fund that the effect of FDI and the impact of private sector investment on the economic growth of Russia is significant. In contrast, the impact of R&D is insignificant to the economic growth of Russia. The study is of great significance as it has raised the importance of R&D for industrialization, FDI, and PSI for economic growth and new venture creation for developing countries.

The Effect of Human Rights Sensitivity and Perception Level of Patient Rights on Adaptation to the First-year Clinical Practice (임상실습 1년차의 인권감수성, 환자권리에 대한 인식수준이 임상실습적응에 미치는 영향)

  • Jiwon Kim;Je, Nam-Joo;Jeong-seok Hwa
    • Korea Journal of Hospital Management
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    • v.28 no.2
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    • pp.1-8
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    • 2023
  • Purpose: This study was conducted to identify the impact of human rights sensitivity and patient rights awareness of first-year students in clinical practice on clinical practice adaptation and to prepare practical and systematic personality development program education alternatives to foster high-quality medical personnel. Method: As for the research method, an online survey of 155 medical and nursing students from two universities in G-do (76 medical students and 79 nursing students) was conducted, and the collected data were T-test, ANOVA, Scheffe test, Pearson's correlation coefficient and step-by-step multiple regression analysis using SPSS WIN/25.0. Findings: The results of the study are as follows. First, as a result of analyzing the differences in each variable according to general characteristics, human rights sensitivity had a significant impact on gender, patient rights recognition on personality type, and clinical practice adaptation had a significant impact on major selection motivation. Second, the factors affecting the adaptation of first-year college students to clinical practice had a significant impact on extroverted personality and patient rights perception among personality types (regression model results F=6.38 (p<).001), 24.2% explanatory power). Conclusion: This study suggests that education and policy efforts are needed to foster accurate awareness of human rights issues by developing flexible and flexible extracurricular activity programs in the operation of the curriculum to strengthen medical and nursing students' ability to adapt to clinical practice and improve awareness of human rights issues.

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The Impact of Employee's Attributes on Corporate Pension Insurance Products Preference (기업연금보험상품 선호도에 대한 종업원 속성의 영향)

  • Joo, Heon
    • The Korean Journal of Franchise Management
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    • v.7 no.2
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    • pp.27-35
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    • 2016
  • Purpose - The primary objective of this study is to investigate the impact of employee characteristics on employees' preference towards corporate pension products. This study can provide a guidance for maximization of benefits for employees and their affiliated corporation. Employee characteristics include average length of labour, wage system of annual salary, age, types of interest rates and size of corporation. Existing research generally concentrate on vitalizations of corporate pension product raising an imperfection, improvements, tax benefit analysis and legal consideration. Thus, this study intensively analyses the effect of employee attributes on firms' decision for corporate pension products, such as DB(defined benefit) and DC(defined contribution) type. Research design, data, and methodology - The data were collected using self-administrated questionnaire survey on corporate pension products from CEOs or HR directors 250 foreign-invested companies', purchasing pension plans in practice with domestic financial trustees (insurance companies, banks and security companies). Hypotheses testing was conducted using Logistic Regression analysis with SPSS/PC+ 21.0. Results - The findings of the study are as follows. Employees with the long length of labour are more likely to have DB plan; more likely to prefer DC plan with the dividend distribution product regarding the types of interest rate. SMEs(less than 100 employees) are more likely to select DC plan whereas high fluctuation in wage with annual salary has no impacts. In addition, the ages has no significant effect on the preference. Conclusions - This study has examined with the empirical testing that employees' variable attributes and qualities are one of the vital factors for corporation pension plan selection. Currently, majority employees are highly likely to join DB plan and Defined interest types. Corporation with less than 10 employees prefer IRP scheme while most of corporation are intended to join DC plan. In a very near future, corporation more than 300 employees will be required to purchase mandatory plan under national regulation. For maximization of employees' contentment to corporation pension insurance and for complementing the flaws of existing plans, the future studies shall also research in a perspective of employee benefit.

A Study on Bag Purchasing Behaviors and Design Preferences - Focusing on Comparative analysis by Sex and Age group - (가방 구매행동과 디자인 선호도 연구 - 성별과 연령집단에 따른 비교분석을 중심으로 -)

  • Mi-sook Lee
    • Journal of the Korea Fashion and Costume Design Association
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    • v.25 no.3
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    • pp.1-16
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    • 2023
  • The purposes of this study were to investigate bag purchasing behaviors and design preferences of male and female adult consumers, and to find the differences depending on sex and age variable. A survey was conducted on 400 male and female adults from 20s to 50s. The questionnaire consisted of bag purchase behaviors, bag design preferences, and the subjects' demographic characteristics. The data were analyzed by Cronbach's α, factor analysis, x2 test and t-test using SPSS. The results were as follows. First, as bag selection criteria, four factors (practicality, symbolism, aesthetics, and economics) were derived, and adult consumers considered economics as the most important among the factors. As for purchasing information sources, three factors (media, human resources, and store) were derived, and adult consumers considered human resources and store information sources more important than media. The main motive for purchasing bags was age and damage of the owned products, and Internet shopping malls were the most common purchasing place. The average annual cost of purchasing bags was 100,000 to 300,000 won, and the frequency of purchase was about once a year. Second, as bag preference images, four factors (individual, romantic, active, and classic image) were derived, and adult consumers preferred classic images the most. The shoulder bag was the most preferred as the bag shape, and black was the most preferred bag color. For the material, natural leather was the most preferred, and for the size, medium size was the most preferred. Third, bag purchasing behaviors and design preferences showed many significant differences according to the sex and age of the consumers. Therefore, the results of this study suggests that bag companies need to establish product development and marketing strategies in consideration of differences according to the sex and age group of adult consumers.

Achieving Relative Loss Differentiation using D-VQSDDP with Differential Drop Probability (차별적이니 드랍-확률을 갖는 동적-VQSDDP를 이용한 상대적 손실차별화의 달성)

  • Kyung-Rae Cho;Ja-Whan Koo;Jin-Wook Chung
    • Proceedings of the Korea Information Processing Society Conference
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    • 2008.11a
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    • pp.1332-1335
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    • 2008
  • In order to various service types of real time and non-real time traffic with varying requirements are transmitted over the IEEE 802.16 standard is expected to provide quality of service(QoS) researchers have explored to provide a queue management scheme with differentiated loss guarantees for the future Internet. The sides of a packet drop rate, an each class to differential drop probability on achieving a low delay and high traffic intensity. Improved a queue management scheme to be enhanced to offer a drop probability is desired necessarily. This paper considers multiple random early detection with differential drop probability which is a slightly modified version of the Multiple-RED(Random Early Detection) model, to get the performance of the best suited, we analyzes its main control parameters (maxth, minth, maxp) for achieving the proportional loss differentiation (PLD) model, and gives their setting guidance from the analytic approach. we propose Dynamic-multiple queue management scheme based on differential drop probability, called Dynamic-VQSDDP(Variable Queue State Differential Drop Probability)T, is proposed to overcome M-RED's shortcoming as well as supports static maxp parameter setting values for relative and each class proportional loss differentiation. M-RED is static according to the situation of the network traffic, Network environment is very dynamic situation. Therefore maxp parameter values needs to modify too to the constantly and dynamic. The verification of the guidance is shown with figuring out loss probability using a proposed algorithm under dynamic offered load and is also selection problem of optimal values of parameters for high traffic intensity and show that Dynamic-VQSDDP has the better performance in terms of packet drop rate. We also demonstrated using an ns-2 network simulation.